CN102895500A - 一种治疗胆道炎的中药 - Google Patents
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Abstract
本发明涉及一种治疗胆道炎的中药，由以下重量配比的药材制备而成：沉香8份、血竭6份、羚羊角8份、海马4份、夏枯草12份、金腰9份、金樱子10份、制马钱子14份、何首乌9份、天青地白12份、三颗针6份、百合12份。临床实验证明，本发明能够安全有效治疗胆道炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗胆道炎的中药。
背景技术
胆道炎症以胆管炎症为主者称胆管炎（cholangitis），以胆囊炎症为主者称胆囊炎（cholecystitis）。两者常同时发生，其病因、发病机制以及病理变化大致相同，多是在胆汁淤积的基础上继发细菌（主要为大肠杆菌、副大肠杆菌和葡萄球菌等）感染所致。细菌可经淋巴道或血道到达胆道，也可从肠道经十二指肠乳头逆行进入胆道。在我国以后者更为常见。可分为急性和慢性两种类型。
对于胆道炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
沉香【来源】 为双子叶植物药瑞香科乔木植物沉香Aquilaria agallocha 或白木香A. sinensis (Lour.) Gilg 在受到自然界的伤害或受到人为破坏以后在自我修复的过程中分泌出的油脂受到真菌的感染，所凝结成的分泌物。【功能主治】降气温中，暖肾纳气。治气逆喘息，呕吐呃逆，脘腹胀痛，腰膝虚冷，大肠虚秘，小便气淋，男子精冷。
血竭【来源】别名：骐驎竭、海蜡、麒麟血、木血竭。棕榈科植物麒麟竭果实和藤茎中的树脂。【功能主治】内服活血散瘀，定痛，外用止血生肌，敛疮。主治：①淤血经闭、痛经，产后瘀阻。②症瘕痞块，胸腹刺痛。③跌打损伤，淤血肿痛。④外伤出血，溃疡不敛。
羚羊角【来源】羚羊，脊椎动物门，哺乳纲，偶蹄目，洞角科，别名高鼻羚羊。年均可捕捉，捕得后，将角从基部锯下。削成薄片，或磨成粉末备用。【功能主治】平肝息风；清肝明目；凉血解毒。用于高热惊痫，神昏痉厥，子痫抽搐，癫痫发狂，头痛眩晕，目赤翳障，温毒发斑，痈肿疮毒。
海马【来源】为海龙科动物克氏海马、刺海马、大海马、斑海马或日本海马除去内脏的全体。【功能主治】补肾壮阳，消症瘕。主治：肾虚阳痿、难产、症瘕、疔疮肿毒等症。连翘【来源】连翘为木犀科植物连翘的果实，内含挥发油，连翘酚，黄酮甙，生物碱等；【功能主治】连翘有广谱抗菌作用，抗炎、镇吐、利尿和强心；所含黄酮甙能增强毛细血管的致密度，其性微寒，味苦，清热解毒，散结消肿，适用于温热，丹毒，斑疹，痈疡肿毒及过敏性紫癜等。
夏枯草 【来源】夏枯草为唇形科植物夏枯草的花卉或全草，内含三萜皂甙及其甙元齐墩果酸，挥发油及维生素，氯化钾等。【功能主治】其性寒，味苦、辛，功能清肝火，散郁结，降血压，适用于肝火上炎所致的目赤肿痛，目珠疼痛，羞明流泪、头痛、眩晕等；用于痰火郁结所致的瘰疠，瘿瘤等。
金腰【来源】虎耳草科金腰Chrysosplenium grayanum Maxim.，以全草入药。【功能主治】排脓解毒。外用治黑头疔疮。
金樱子【来源】常绿蔓性灌木，无毛根皮提制栲胶；果实入药。【功能主治】止咳平喘，抗痉挛，有利尿、补肾作用；抗菌消炎，降血脂。叶有解毒消肿作用；根药用，能活血散瘀、拔毒收敛、祛风驱湿。
制马钱子【来源】马钱科植物云南马钱的干燥成熟种子。主要成分是士的宁。【功能主治】治伤寒热病，咽喉痹痛，消痞块，散血热，消肿毒。治痈疽，恶疮。
何首乌【来源】为蓼科多年生缠绕藤本植物。根细长，末端成肥大的块根，外表红褐色至暗褐色。植物的块根、藤茎及叶均可供药用。【功能主治】解毒、润肠通便、消痈；补益精血、乌须发、强筋骨、补肝肾。 促进造血功能 ，增强免疫功能 。
天青地白【来源】于菊科植物日本鼠曲草全草。甘，凉。【功能主治】解表，清热，明目，利尿的功效。治疗感冒，咳嗽，头痛，喉痛，目赤翳鄣，小便热闭，淋浊，白带，痈肿，疔疮。
三颗针【来源】于小檗科植物刺黑珠、毛叶小檗、黑石珠等的根皮或茎皮。性寒，微苦。【功能主治】清热，利湿，散瘀的功效。治疗赤痢，黄疸，咽痛，目赤，跌打损伤。
百合【来源】百合科百合属多年生草本球根植物，其花、鳞状茎均可入药，是一种药食兼用的花卉。【功能主治】性微寒平，具有清火、润肺、安神的功效。
发明内容
本发明旨在提供一种治疗胆道炎的中药，通过选择合适的药材及其配比，达到安全有效治愈胆道炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗胆道炎的中药，其特征在于，由以下重量配比的药材制备而成：沉香8份、血竭6份、羚羊角8份、海马4份、夏枯草12份、金腰9份、金樱子10份、制马钱子14份、何首乌9份、天青地白12份、三颗针6份、百合12份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年6月-2011年10月间共收集67例胆道炎的门诊患者，年龄12-48岁，病程0.5-4年。随机分为：治疗组45例，空白组22例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) |
| 治疗组 | 45 | 5（11.1%） | 34（75.6%) | 6(13.3%) | 86.7% |
| 空白组 | 22 | 0 | 3（13.6%） | 19（86.4%） | 13.6% |
可见，本发明制得的药物能够安全有效治胆道炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：沉香8克、血竭6克、羚羊角8克、海马4克、夏枯草12克、金腰9克、金樱子10克、制马钱子14克、何首乌9克、天青地白12克、三颗针6克、百合12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗胆道炎。口服，每日分早晚两次服用。
具体实施例2
称取：沉香8克、血竭6克、羚羊角8克、海马4克、夏枯草12克、金腰9克、金樱子10克、制马钱子14克、何首乌9克、天青地白12克、三颗针6克、百合12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗胆道炎。口服，每日分早晚两次服用。
具体实施例3
称取：沉香8克、血竭6克、羚羊角8克、海马4克、夏枯草12克、金腰9克、金樱子10克、制马钱子14克、何首乌9克、天青地白12克、三颗针6克、百合12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗胆道炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗胆道炎的中药，其特征在于，由以下重量配比的药材制备而成：沉香8份、血竭6份、羚羊角8份、海马4份、夏枯草12份、金腰9份、金樱子10份、制马钱子14份、何首乌9份、天青地白12份、三颗针6份、百合12份。
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