CN103055137B - 一种治疗慢性胰腺炎的中药 - Google Patents
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Abstract
本发明涉及一种治疗慢性胰腺炎的中药，由以下重量配比的药材制备而成：川芎12份、五灵脂10份、鸡血藤9份、牛膝12份、茺蔚子12份、金腰10份、当归14份、何首乌14份、百合12份、天门冬12份、玉竹10份。临床实验证明，本发明能够安全有效治疗慢性胰腺炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗慢性胰腺炎的中药。
背景技术
慢性胰腺炎是指胰腺实质的坏死、出血、脂肪坏死等引起的局部及全身多器官一系列的损害。本病病情危重，死亡率极高。急性胰腺炎是常见的急腹症之一。急性胰腺炎不仅是胰腺的局部炎症病变，而且是涉及多个脏器的全身性疾病。慢性胰腺炎是由于胆道疾病或酒精中毒等因素导致的胰腺实质进行性损害和纤维化，常伴钙化、假性囊肿及胰岛细胞减少或萎缩。主要表现为腹痛、消瘦、营养不良、腹泻或脂肪痢，后期可出现腹部包块、黄疸和糖尿病等。
对于慢性胰腺炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
川芎【来源】伞形科植物川芎Ligusticum chuanxiong Hort.的干燥根茎，栽后第2年5月下旬至6月上旬，挖出根茎，抖掉泥土，除去茎叶，炕干。【功能主治】活血祛瘀；行气开郁；祛风止痛，疗头痛之首选药物。月经不调；经闭痛经；产后瘀滞腥痛；症瘕肿块；胸胁疼痛；头痛眩晕；风寒湿痹；跌打损伤。
五灵脂【来源】为鼯鼠科动物橙足鼯鼠Trogopterus Xanthipes Mi lne-Edwards或飞鼠科动物小飞鼠Pteromys volans L.的干燥粪便。全年可收采。将砂石、泥土等杂质除净。【功能主治】活血散瘀，炒炭止血。用于心腹淤血作痛，痛经，血瘀经闭，产后淤血腹痛；炒炭治崩漏下血；外用治跌打损伤，蛇、虫咬伤。
鸡血藤【来源】豆科植物密花豆Spatholobus suberectus Dunn的干燥藤茎。【功能主治】性甘，温。归肝、肾经。功能主治：补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。
牛膝【来源】苋科植物牛膝Achyranthes bidentata Bl.的干燥根。牛膝根拣去杂质，洗净，润软，去芦，切段，晒干。酒牛膝：取牛膝段，用黄酒喷淋拌匀，闷润后，置锅内炒至微干，取出放凉即得。【功能主治】补肝肾；强筋骨；活血通经；引火(血)下行；利尿通淋。
茺蔚子【来源】该品为唇形科植物益母草Leonurus japonicus Houtt.的干燥成熟果实。秋季果实成熟时采割地上部分，晒干，打下果实，除去杂质。【功能主治】活血调经，清肝明目。用于月经不调，经闭，痛经，目赤翳障，头晕胀痛。
金腰【来源】虎耳草科金腰Chrysosplenium grayanum Maxim.，以全草入药。【功能主治】排脓解毒。外用治黑头疔疮。
当归【来源】学名：Angelica sinensis，多年生草本植物，茎带紫色。各地均有栽培。根可入药，是最常用的中药之一。【功能主治】抗缺氧、调节机体免疫功能、抗癌、护肤美容、补血活血、抑菌、抗动脉硬化。
何首乌【来源】为蓼科多年生缠绕藤本植物。根细长，末端成肥大的块根，外表红褐色至暗褐色。植物的块根、藤茎及叶均可供药用。【功能主治】解毒、润肠通便、消痈；补益精血、乌须发、强筋骨、补肝肾。促进造血功能，增强免疫功能
百合【来源】百合科百合属多年生草本球根植物，其花、鳞状茎均可入药，是一种药食兼用的花卉。【功能主治】性微寒平，具有清火、润肺、安神的功效。
天门冬【来源】百合科植物。又名天冬。性寒，味甘，微苦。具有养阴清热，润肺滋肾的功效。【功能主治】用于治阴虚发热、咳嗽吐血、肺痈、咽喉肿痛、消渴、便秘等病症。
玉竹【来源】为百合科多年生草本植物。根茎横走，肉质黄白色，密生多数须根。晒干，或蒸透后，揉至半透明，晒干，切厚片或段用。【功能主治】滋阴润肺；养胃生津。燥咳；劳嗽；热病阴液耗伤之咽干口渴；内热消渴；阴虚外感；头昏眩晕；筋脉挛痛。
发明内容
本发明旨在提供一种治疗慢性胰腺炎的中药，通过选择合适的药材及其配比，达到安全有效治愈慢性胰腺炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗慢性胰腺炎的中药，其特征在于，由以下重量配比的药材制备而成：川芎12份、五灵脂10份、鸡血藤9份、牛膝12份、茺蔚子12份、金腰10份、当归14份、何首乌14份、百合12份、天门冬12份、玉竹10份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年11月-2011年9月间共收集85例慢性胰腺炎的门诊患者。随机分为：治疗组60例，空白组25例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
可见，本发明制得的药物能够安全有效治慢性胰腺炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：川芎12克、五灵脂10克、鸡血藤9克、牛膝12克、茺蔚子12克、金腰10克、当归14克、何首乌14克、百合12克、天门冬12克、玉竹10克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗慢性胰腺炎。口服，每日分早晚两次服用。
具体实施例2
称取：川芎12克、五灵脂10克、鸡血藤9克、牛膝12克、茺蔚子12克、金腰10克、当归14克、何首乌14克、百合12克、天门冬12克、玉竹10克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗慢性胰腺炎。口服，每日分早晚两次服用。
具体实施例3
称取：川芎12克、五灵脂10克、鸡血藤9克、牛膝12克、茺蔚子12克、金腰10克、当归14克、何首乌14克、百合12克、天门冬12克、玉竹10克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗慢性胰腺炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗慢性胰腺炎的中药，其特征在于，由以下重量配比的药材制备而成：川芎12份、五灵脂10份、鸡血藤9份、牛膝12份、茺蔚子12份、金腰10份、当归14份、何首乌14份、百合12份、天门冬12份、玉竹10份。
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| 《慢性胰腺炎的中医辨治》;王喜媚;《时珍国医国药》;20031231;第14卷(第4期);第229页 * |
| 中医药在慢性胰腺炎治疗中的作用;梁晓强等;《中国临床康复》;20061220;第10卷(第47期);第124-126页 * |
| 中医辨证分型治疗慢性胰腺炎;余在先等;《中国医药科学》;20110831;第1卷(第16期);第100-101页 * |
| 余在先等.中医辨证分型治疗慢性胰腺炎.《中国医药科学》.2011,第1卷(第16期),第100-101页. |
| 梁晓强等.中医药在慢性胰腺炎治疗中的作用.《中国临床康复》.2006,第10卷(第47期),第124-126页. |
| 王喜媚.《慢性胰腺炎的中医辨治》.《时珍国医国药》.2003,第14卷(第4期),第. |
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