CN103071038A - Medicine composition for treating cervical spondylosis - Google Patents
Medicine composition for treating cervical spondylosis Download PDFInfo
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- CN103071038A CN103071038A CN2013100335462A CN201310033546A CN103071038A CN 103071038 A CN103071038 A CN 103071038A CN 2013100335462 A CN2013100335462 A CN 2013100335462A CN 201310033546 A CN201310033546 A CN 201310033546A CN 103071038 A CN103071038 A CN 103071038A
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Abstract
The invention relates to a medicine composition for treating cervical spondylosis through taking traditional Chinese medicines as raw materials. A method comprises the steps that selected and cleanly-washed semen persicae, carthamus tinctorius, radix angelicae dahuricae, chrysanthemum, selfheal and radix ophiopogonis are taken, mixed uniformly and decocted with water; the quantity of the added water is 2-4 times the weight of the medicines; extraction is conducted for 3 times, 1h each time; decocted liquids are merged and filtered; a filtrate is concentrated into thick paste with relative density of above 1.30 (at 60 DEG C); the thick paste is subjected to pressure reduction drying at 60-80 DEG C, and smashed into 80-100-mesh powder; and conventional medicine auxiliary materials are added, and prepared into capsules according to the conventional method. The medicine composition consists of the traditional Chinese medicines, and has effects of activating blood circulation, promoting qi circulation, expelling wind, relieving exterior syndromes, eliminating dampness and alleviating pain. The medicine composition takes effects rapidly and is small in side effect, and the cervical spondylosis does not recur easily when the medicine composition is used for treating the cervical spondylosis.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of cervical spondylosis, particularly relate to a kind of pharmaceutical composition of the treatment cervical spondylosis for preparing take Chinese medicine as crude drug.
Background technology
Cervical spondylosis refers to that the plump hypertrophy of degeneration of cervical intervertebral disc, cervical vertebra and neck injury etc. cause hyperosteogeny of cervical vertebra, or prolapse of intervertebral disc, ligament thicken, and stimulates or compressing cervical spinal, cervical region are neural, blood vessel and produce the clinical syndrome of series of symptoms.Main manifestations is neck and shoulder pain, dizziness headache, upper limb numbness, amyotrophy, the two lower limb spasm of severe patient, difficulty in walking, even quadriplegia, and paralysis appears in the defecation obstacle.Multiple at middle-aged and elderly people, male's sickness rate is higher than the women.
Treatment to cervical spondylosis mainly is divided into naturopathy and Drug therapy, naturopathy mainly comprises the methods such as traction, physical therapy, operation, wherein most patients adopt traction, physical therapy more, operation only is applied to serious sufferer, traction in the naturopathy and physical therapy are expectant treatment, take effect slow, treatment time is long, and Drug therapy adopts Western medicine more, side effect is large, is difficult for long-time the use.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of cervical spondylosis, this pharmaceutical composition by Chinese medicine form have blood-activating and qi-promoting, dispersing wind, relieving exterior syndrome, the effect of damp-clearing pain-relieving can play instant effect, little, the difficult purpose that recurs of side effect to the treatment of cervical spondylosis.
Pharmaceutical composition of the present invention is that the medicine by following parts by weight is that crude drug prepares:
Semen Persicae 10~20 Flos Carthamis 10~20 Radixs Angelicae Dahuricae 10~20
15~30 Radix Ophiopogonis 15~30 of Flos Chrysanthemi 10~30 Spica Prunellaes.
Preferably, pharmaceutical composition of the present invention is that the medicine by following parts by weight is that crude drug prepares:
Semen Persicae 12~15 Flos Carthamis 14~16 Radixs Angelicae Dahuricae 12~15
20~25 Radix Ophiopogonis 20~25 of Flos Chrysanthemi 18~22 Spica Prunellaes.
Aforementioned pharmaceutical compositions can be made any peroral dosage form on the pharmaceutics, such as pill, tablet, powder etc., the preferred dosage form of the present invention is capsule.
The concrete preparation method of medicine of the present invention being made capsule is:
1), said medicine is decocted with water by described parts by weight mix homogeneously, amount of water is 2~4 times of drug weight, extracts each 0.5~1.5 hour 1~3 time;
2), merge above-mentioned decocting liquid, filter, filtrate is concentrated into relative density thick paste of (60 ℃) more than 1.30,
3), with thick paste at 60~80 ℃ of lower drying under reduced pressure, be ground into 80~100 purpose medicated powder, add the conventional medicine adjuvant, make according to a conventional method capsule.
The traditional Chinese medical science thinks that cervical spondylosis mostly is wind-cold damp pathogen and takes advantage of a weak point richly mutually with QI and blood, or on ordinary days fall sick from overwork, the muscles and bones strain, the QI and blood knot that becomes silted up is given birth in the phlegm-damp, the venation ridge due to obstructed, so the Therapeutic Principle is blood-activating and qi-promoting, dispersing wind, relieving exterior syndrome, damp-clearing pain-relieving.In the prescription of the present invention, Semen Persicae, Flos Carthami have activating blood circulation to dissipate blood stasis, the phoenix pain relieving of dispelling; The Flos Chrysanthemi dispelling wind and heat pathogens, suppressing the hyperactive liver makes eye bright; The Radix Angelicae Dahuricae dispels the wind, dampness, detumescence, pain relieving; Spica Prunellae liver heat removing, eliminating stagnation, diuresis; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.All medicines share blood-activating and qi-promoting, dispersing wind, relieving exterior syndrome, and damp-clearing pain-relieving is used for the treatment of cervical spondylosis, the characteristics that have instant effect, have no side effect.
For further investigating clinical efficacy and the safety of medicine of the present invention, select 102 routine Patients with Cervical Spondylopathies that the curative effect of medicine of the present invention has been carried out clinical observation, male's 55 examples, women's 47 examples in 102 examples, minimum 25 years old of age, maximum 58 years old, the course of disease is the shortest 3 months, and was the longest 6 months.102 routine patients are divided into treatment group and matched group, treatment group 55 people, matched group 47 people.
Diagnostic criteria
1. chronic strain or trauma history are arranged, or cervical vertebra congenital malformation, cervical vertebra degeneration are arranged;
2. there are neck, shoulder and back ache, headache and dizzy, neck board is hard, upper limb numbness;
3. the cervical region movable function is limited, and often there is tenderness at upper angle in the pathological changes cervical spine, Ipsilateral scapula, can touch strip scleroma, can have the upper limb muscular strength to weaken and amyotrophy, and the brachial plexus distraction test is positive.The pressure head test is positive;
4.X taking the photograph sheet, the line normotopia shows, the uncovertebral joint hypertrophy, and mouth-open can have the cutter shape prominent partially askew, and the side position is taken the photograph sheet and is shown that cervical curvature straightens, and narrowing of intervertebral space has hyperosteogeny or ligament calcification, and loxosis is taken the photograph the visible intervertebral foramina of sheet and is diminished.CT and magnetic resonance examination are meaningful to qualitative level diagnosis.
Therapeutic Method
Treatment group adopts the capsule of medicine of the present invention to treat, and takes each 3 every day 2 times;
Matched group adopts the cervicodynia sheet to treat every day 3 times, each 4.
Criterion of therapeutical effect
Cure: original various disease disappears, and muscular strength is normal, and neck, limb functional recover are normal, can participate in and normally work and work;
Take a turn for the better: original various sx↓, neck, shoulder and back ache alleviate, and neck, limb function improve;
Do not heal: symptom is without improvement.
The curative effect comparative result sees Table 1 after two groups of case treatments.
?
Curative effect relatively after the table 1 liang group case treatment
Group | The example number | Cure n(%) | Improvement n(%) | N(% more) | Total effective rate n(%) |
Matched group | 47 | 15(31.9) | 17(36.2) | 15(31.9) | 32(68.1) |
Treatment group | 55 | 35(63.7) | 18(32.7) | 2(3.6) | 53(96.4) |
Statistical result showed, the treatment group curative effect obviously is better than matched group, and two group differences are remarkable,
P<0.05.
The specific embodiment
Embodiment 1
Get Semen Persicae 100g, Flos Carthami 100g that selected, clear water cleans, Radix Angelicae Dahuricae 100g, Flos Chrysanthemi 100g, Spica Prunellae 150g, Radix Ophiopogonis 150g, the said medicine mix homogeneously is decocted with water, amount of water is 2~4 times of drug weight, extracts each 0.5 hour 3 times; Merge above-mentioned decocting liquid, filter, filtrate is concentrated into relative density thick paste of (60 ℃) 1.30 or more, and thick paste at 60 ℃ of lower drying under reduced pressure, is ground into 80~100 purpose medicated powder, and interpolation conventional medicine adjuvant is made capsule according to a conventional method.
Embodiment 2
Get Semen Persicae 200g, Flos Carthami 200g that selected, clear water cleans, Radix Angelicae Dahuricae 200g, Flos Chrysanthemi 300g, Spica Prunellae 300g, Radix Ophiopogonis 300g, the said medicine mix homogeneously is decocted with water, amount of water is 2~4 times of drug weight, extracts each 1.5 hours 3 times; Merge above-mentioned decocting liquid, filter, filtrate is concentrated into relative density thick paste of (60 ℃) 1.30 or more, and thick paste at 60~80 ℃ of lower drying under reduced pressure, is ground into 80~100 purpose medicated powder, and interpolation conventional medicine adjuvant is made capsule according to a conventional method.
Embodiment 3
Get Semen Persicae 140g, Flos Carthami 150g that selected, clear water cleans, Radix Angelicae Dahuricae 140g, Flos Chrysanthemi 200g, Spica Prunellae 220g, Radix Ophiopogonis 230g, the said medicine mix homogeneously is decocted with water, amount of water is 2~4 times of drug weight, extracts each 1 hour 3 times; Merge above-mentioned decocting liquid, filter, filtrate is concentrated into relative density thick paste of (60 ℃) 1.30 or more, and thick paste at 60~80 ℃ of lower drying under reduced pressure, is ground into 80~100 purpose medicated powder, and interpolation conventional medicine adjuvant is made capsule according to a conventional method.
Claims (2)
1. pharmaceutical composition for the treatment of cervical spondylosis is that the medicine by following parts by weight is that crude drug prepares:
Semen Persicae 10~20 Flos Carthamis 10~20 Radixs Angelicae Dahuricae 10~20
15~30 Radix Ophiopogonis 15~30 of Flos Chrysanthemi 10~30 Spica Prunellaes.
2. the pharmaceutical composition for the treatment of cervical spondylosis according to claim 1 is that the medicine by following parts by weight is that crude drug prepares:
Semen Persicae 12~15 Flos Carthamis 14~16 Radixs Angelicae Dahuricae 12~15
20~25 Radix Ophiopogonis 20~25 of Flos Chrysanthemi 18~22 Spica Prunellaes.
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1478521A (en) * | 2003-05-16 | 2004-03-03 | 石新民 | Medicine for relaxing muscles and tendons and activiating colleterals and pain dispelling |
CN1660168A (en) * | 2004-02-23 | 2005-08-31 | 张梦麟 | Formula of Chinese traditional medicine for core of health care pillow |
CN101020004A (en) * | 2007-03-19 | 2007-08-22 | 殷彬 | Migraine treating Chinese medicine |
CN101229356A (en) * | 2008-01-10 | 2008-07-30 | 骆峰 | External wad for treating cervical spondylosis |
CN202287453U (en) * | 2011-10-25 | 2012-07-04 | 晓健科技(大连)有限公司 | Traditional Chinese Medicinal pillow for treating cervical spondylosis |
-
2013
- 2013-01-29 CN CN2013100335462A patent/CN103071038A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1478521A (en) * | 2003-05-16 | 2004-03-03 | 石新民 | Medicine for relaxing muscles and tendons and activiating colleterals and pain dispelling |
CN1660168A (en) * | 2004-02-23 | 2005-08-31 | 张梦麟 | Formula of Chinese traditional medicine for core of health care pillow |
CN101020004A (en) * | 2007-03-19 | 2007-08-22 | 殷彬 | Migraine treating Chinese medicine |
CN101229356A (en) * | 2008-01-10 | 2008-07-30 | 骆峰 | External wad for treating cervical spondylosis |
CN202287453U (en) * | 2011-10-25 | 2012-07-04 | 晓健科技(大连)有限公司 | Traditional Chinese Medicinal pillow for treating cervical spondylosis |
Non-Patent Citations (3)
Title |
---|
任晓丹: "补阳还五汤临床运用", 《四川中医》 * |
刘晋熹: ""辩证分型治疗椎动脉型颈椎病的疗效观察"", 《中国医药指南》 * |
葛楠: ""浅谈杨国英治病特点"", 《内蒙古中医药》 * |
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