CN103041100A - Traditional Chinese medicine preparation for treatment of hypomenorrhea and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treatment of hypomenorrhea and preparation method thereof Download PDFInfo
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- CN103041100A CN103041100A CN2012105403758A CN201210540375A CN103041100A CN 103041100 A CN103041100 A CN 103041100A CN 2012105403758 A CN2012105403758 A CN 2012105403758A CN 201210540375 A CN201210540375 A CN 201210540375A CN 103041100 A CN103041100 A CN 103041100A
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Abstract
The present invention discloses a traditional Chinese medicine preparation for treatment of hypomenorrhea and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation includes: semen cuscutae, eucommia ulmoides, rehmannia glutinosa, dogwood, Chinese wolfberry, Chinese angelica, astragalus mongholicus, Chinese yam, peach kernel, ligusticum wallichii and poria. The traditional Chinese medicine preparation for treatment of hypomenorrhea has the efficacy of tonifying kidney and nourishing blood, augmenting qi and regulating menstruation, and is a traditional Chinese medicine composition which is safe and reliable, without any side effects, high in usage rate of the active ingredients, and quick in effect.
Description
Technical field
The invention belongs to Chinese medicine composition, relate to a kind of Chinese medicine preparation for the treatment of hypomenorrhea and preparation method thereof.
Background technology
Hypomenorrhea is that menstrual cycle is normal, and menstrual blood volume obviously reduces, or the deficiency of time 2 days of passing through, and very person's drop is clean person.Ancient books has title " a small amount of menses and menstruating unsmoothly ", " water purification is few ", " very few through measuring ".It is generally acknowledged that Hypomenorrhea is hypomenorrhea in 20ml.The general cycle of primary disease is still normal, but sometimes also unusual with the cycle and see, measures fewly such as companion in advance, and the later stage companion measures few, and the latter often is the prodrome of amenorrhea.The hypomenorrhea that causes behind the disease such as uterine hypoplasia, hypogonadism and the family planning operation in the western medicine can be treated with reference to primary disease.The primary disease pathogeny has void that reality is arranged.Void person is many because of the damage of essence insufficiency of blood, and sea of blood virtual loss, the weary source of menses are appointed in punching; Reality person is many by stopping in the blood stasis, or stagnation of phlegm-damp, and punching is appointed and is jammed, hematogenous blockage and hypomenorrhea.The traditional Chinese medical science is divided the pattern of syndrome Coryza Treated by Syndrome Differentiation such as nephrasthenia syndrome, syndrome of deficiency of blood, syndrome of blood stasis, phlegm-damp card clinically, obtains good curative effect.The medicine for the treatment of in the market hypomenorrhea is a lot, and some curative effects are all arranged.But effect is not very good.Invent again effective Chinese medicine composition of a kind of i.e. safety, be significant.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of hypomenorrhea, it have tonify Qi of the kidney, the effect of nourishing blood for regulating menstruation.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine preparation for the treatment of hypomenorrhea is made by each raw material of following weight portion: Semen Cuscutae 15-25 part, Cortex Eucommiae 5-15 part, Radix Rehmanniae Preparata 10-30 part, Fructus Corni 5-15 part, Fructus Lycii 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 15-30 part, Semen Persicae 3-9 part, Rhizoma Chuanxiong 3-9 part, Poria 5-15 part.
Preferably, each parts by weight of raw materials is: 20 parts of Semen Cuscutae, 10 parts of the Cortexs Eucommiae, 20 parts in Radix Rehmanniae Preparata, 10 parts of Fructus Corni, 10 parts of Fructus Lyciis, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 20 parts of Rhizoma Dioscoreaes, 6 parts in Semen Persicae, 6 parts of Rhizoma Chuanxiongs, 10 parts in Poria.
Pharmacological action:
Semen Cuscutae: acrid-sweet flavor, property is flat.Enter liver, kidney channel.Invigorating the liver and kidney is arranged, beneficial marrow, the effect that makes eye bright.Control soreness of waist and knee joint, seminal emission is quenched one's thirst, dripping urination, and order is dark.
The Cortex Eucommiae: Gan Weixin, temperature.Have invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.The yin nourishing of enriching blood, the effect of life essence-filling, marrow-benefitting.Be used for blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, the disease such as pass out semen, quench one's thirst.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Liver and kidney tonifying is restrained astringent or styptic treatment for spontaneous sweating controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping and is only collapsed hidroschesis, also has in addition promoting the production of body fluid to quench thirst.Be used for the soreness of waist and knee joint dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses menoxenia, profuse sweating collapse.Interior-heat is quenched one's thirst.
Fructus Lycii: sweet in the mouth, property is flat.Return liver, kidney, lung meridian.The effect that nourishing the liver, nourishing kidney, lung moistening are arranged.Control caused by liver and kidney deficiency, have a dizzy spell, visual deterioration, soreness of the waist and knees, seminal emission is quenched one's thirst, cough due to consumptive disease.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth, suffering.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Astragali: nature and flavor, sweet, tepor.Return lung, spleen, liver, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.The spleen reinforcing nourishing the stomach is arranged, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling is arranged, loosening bowel to relieve constipation, the effect of relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting is arranged, the effect of wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Poria: sweet in the mouth, light, property is flat.GUIXIN warp, lung meridian, spleen channel, kidney channel.The effect that diuretic, eliminating dampness by diuresis diuresis are arranged.Control dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine.
The used various raw materials of the present invention can be bought from market and obtain, and its specification is that pharmaceutical grade or food stage all can.
Another technical problem to be solved by this invention provides a kind of preparation method for preparing above-mentioned Chinese medicinal capsule.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of preparation method for the treatment of the Chinese medicine preparation of hypomenorrhea comprises:
(1) getting the Cortex Eucommiae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Rhizoma Chuanxiong, Poria, begin percolation after 48 hours with soak with ethanol light to color, and the collection percolate is concentrated into extractum, and is for subsequent use;
Medicinal residues and Semen Cuscutae, Fructus Corni, Fructus Lycii, Semen Persicae, the Rhizoma Dioscoreae of (2) getting (1) gained merge; Water decocted 1 hour, left standstill, and collected and collecting decoction, was concentrated into extractum, and is for subsequent use;
(3) add 95% ethanol at above-mentioned (2) gained extractum and make that to contain alcohol be 70%, fully stir, leave standstill, centrifugal, the supernatant Recycled ethanol, normal pressure is condensed into thick paste;
(4) (1) and (3) gained is merged, add appropriate amount of starch, mixing, reduced vacuum is dry, pulverizes, granulate, drying, granulate is recorded capsule, and get final product.
In the above-mentioned preparation method, the concentration of alcohol that soaks in the step (1) is 90%.
The multiple that step (2) decocts water is 10 times.
Being concentrated into relative density in the step (3) is that 1.08-1.10 (50 ℃~60 ℃) extractum is for subsequent use.
Use the Chinese medicinal capsule of this method preparation, that its advantage is is rapid-action, bioavailability is high, take with easy to carry, can carry out the quality testing of qualitative, quantitative, good stability.Avoided the harmful effect of adjuvant.
The specific embodiment
Embodiment 1
Take by weighing each raw material (unit: g): Semen Cuscutae 20, the Cortex Eucommiae 10, Radix Rehmanniae Preparata 20, Fructus Corni 10, Fructus Lycii 10, Radix Angelicae Sinensis 10, the Radix Astragali 30, Rhizoma Dioscoreae 20, Semen Persicae 6, Rhizoma Chuanxiong 6, Poria 10 by following weight.
(1) getting the Cortex Eucommiae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Rhizoma Chuanxiong, Poria, to begin percolation after 48 hours with 90% soak with ethanol light to color, collects percolate, is concentrated into extractum, for subsequent use;
Medicinal residues and Semen Cuscutae, Fructus Corni, Fructus Lycii, Semen Persicae, the Rhizoma Dioscoreae of (2) getting (1) gained merge; Boiled 1 hour with 10 times of decoctings, leave standstill, collect and collecting decoction, be concentrated into extractum, for subsequent use;
(3) add 95% ethanol at above-mentioned (2) gained extractum and make that to contain alcohol be 70%, fully stir, leave standstill, centrifugal, it is that 1.08-1.10 (50 ℃~60 ℃) extractum is for subsequent use that supernatant Recycled ethanol, normal pressure are concentrated into relative density;
(4) (1) and (3) gained is merged, add appropriate amount of starch, mixing, reduced vacuum is dry, pulverizes, granulate, drying, granulate is recorded capsule, and get final product.
Embodiment 2
Take by weighing each raw material (unit: g): Semen Cuscutae 25, the Cortex Eucommiae 12, Radix Rehmanniae Preparata 20, Fructus Corni 12, Fructus Lycii 10, Radix Angelicae Sinensis 10, the Radix Astragali 25, Rhizoma Dioscoreae 20, Semen Persicae 6, Rhizoma Chuanxiong 6, Poria 12 by following weight.
(1) getting the Cortex Eucommiae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Rhizoma Chuanxiong, Poria, to begin percolation after 48 hours with 90% soak with ethanol light to color, collects percolate, is concentrated into extractum, for subsequent use;
Medicinal residues and Semen Cuscutae, Fructus Corni, Fructus Lycii, Semen Persicae, the Rhizoma Dioscoreae of (2) getting (1) gained merge; Boiled 1 hour with 10 times of decoctings, leave standstill, collect and collecting decoction, be concentrated into extractum, for subsequent use;
(3) add 95% ethanol at above-mentioned (2) gained extractum and make that to contain alcohol be 70%, fully stir, leave standstill, centrifugal, it is that 1.08-1.10 (50 ℃~60 ℃) extractum is for subsequent use that supernatant Recycled ethanol, normal pressure are concentrated into relative density;
(4) (1) and (3) gained is merged, add appropriate amount of starch, mixing, reduced vacuum is dry, pulverizes, granulate, drying, granulate is recorded capsule, and get final product.
Claims (6)
1. a Chinese medicine preparation for the treatment of hypomenorrhea is made by each raw material of following weight portion: Semen Cuscutae 15-25 part, Cortex Eucommiae 5-15 part, Radix Rehmanniae Preparata 10-30 part, Fructus Corni 5-15 part, Fructus Lycii 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Astragali 20-40 part, Rhizoma Dioscoreae 15-30 part, Semen Persicae 3-9 part, Rhizoma Chuanxiong 3-9 part, Poria 5-15 part.
2. a kind of Chinese medicine preparation for the treatment of hypomenorrhea according to claim 1, it is characterized in that the weight portion of each raw material is: 20 parts of Semen Cuscutae, 10 parts of the Cortexs Eucommiae, 20 parts in Radix Rehmanniae Preparata, 10 parts of Fructus Corni, 10 parts of Fructus Lyciis, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 20 parts of Rhizoma Dioscoreaes, 6 parts in Semen Persicae, 6 parts of Rhizoma Chuanxiongs, 10 parts in Poria.
3. a kind of preparation method for the treatment of the Chinese medicine preparation of hypomenorrhea according to claim 1 and 2 comprises the steps:
(1) getting the Cortex Eucommiae, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Rhizoma Chuanxiong, Poria, begin percolation after 48 hours with soak with ethanol light to color, and the collection percolate is concentrated into extractum, and is for subsequent use;
Medicinal residues and Semen Cuscutae, Fructus Corni, Fructus Lycii, Semen Persicae, the Rhizoma Dioscoreae of (2) getting (1) gained merge; Water decocted 1 hour, left standstill, and collected and collecting decoction, was concentrated into extractum, and is for subsequent use;
(3) add 95% ethanol at above-mentioned (2) gained extractum and make that to contain alcohol be 70%, fully stir, leave standstill, centrifugal, the supernatant Recycled ethanol, normal pressure is condensed into thick paste;
(4) (1) and (3) gained is merged, add appropriate amount of starch, mixing, reduced vacuum is dry, pulverizes, granulate, drying, granulate is recorded capsule, and get final product.
4. a kind of preparation method for the treatment of the Chinese medicine preparation of hypomenorrhea according to claim 3 is characterized in that, the concentration of alcohol that soaks in the step (1) is 90%.
5. a kind of preparation method for the treatment of the Chinese medicine preparation of hypomenorrhea according to claim 3 is characterized in that, the multiple that step (2) decocts water is 10 times.
6. a kind of preparation method for the treatment of the Chinese medicine preparation of hypomenorrhea according to claim 3 is characterized in that, being concentrated into relative density in the step (3) is that 1.08-1.10 (50 ℃~60 ℃) extractum is for subsequent use.
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105362682A (en) * | 2015-11-25 | 2016-03-02 | 张立 | External-use medicine for treating hypomenorrhea |
CN105412491A (en) * | 2016-01-15 | 2016-03-23 | 青岛辰达生物科技有限公司 | Pharmaceutic preparation for treating hypomenorrhea and endometritis |
CN105497398A (en) * | 2016-01-14 | 2016-04-20 | 青岛辰达生物科技有限公司 | Medicine composition for treating ureaplasma urealyticum infection accompanying hypomenorrhea |
CN105497426A (en) * | 2016-01-20 | 2016-04-20 | 黄庆辉 | Traditional Chinese medicine for treating blood-insufficiency hypomenorrhea |
CN105833191A (en) * | 2016-05-18 | 2016-08-10 | 汤华淑 | Traditional Chinese medicine composition for treating hypomenorrhea |
CN105833033A (en) * | 2016-05-18 | 2016-08-10 | 刘昌红 | Traditional Chinese medicine composition for treating hypomenorrhea |
CN110898136A (en) * | 2019-11-19 | 2020-03-24 | 安徽医科大学第一附属医院 | Traditional Chinese medicine composition for treating vitreous body and preparation method thereof |
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CN101085153A (en) * | 2007-06-26 | 2007-12-12 | 北京艺信堂医药研究所 | Traditional Chinese medicine preparation for treating hypomenorrhea |
CN101703666A (en) * | 2009-11-16 | 2010-05-12 | 孔德旺 | Chinese medicinal composition for treating irregular menstruation |
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CN101085152A (en) * | 2007-06-26 | 2007-12-12 | 北京艺信堂医药研究所 | Traditional Chinese medicine for treating hypomenorrhea |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105362682A (en) * | 2015-11-25 | 2016-03-02 | 张立 | External-use medicine for treating hypomenorrhea |
CN105497398A (en) * | 2016-01-14 | 2016-04-20 | 青岛辰达生物科技有限公司 | Medicine composition for treating ureaplasma urealyticum infection accompanying hypomenorrhea |
CN105412491A (en) * | 2016-01-15 | 2016-03-23 | 青岛辰达生物科技有限公司 | Pharmaceutic preparation for treating hypomenorrhea and endometritis |
CN105497426A (en) * | 2016-01-20 | 2016-04-20 | 黄庆辉 | Traditional Chinese medicine for treating blood-insufficiency hypomenorrhea |
CN105833191A (en) * | 2016-05-18 | 2016-08-10 | 汤华淑 | Traditional Chinese medicine composition for treating hypomenorrhea |
CN105833033A (en) * | 2016-05-18 | 2016-08-10 | 刘昌红 | Traditional Chinese medicine composition for treating hypomenorrhea |
CN110898136A (en) * | 2019-11-19 | 2020-03-24 | 安徽医科大学第一附属医院 | Traditional Chinese medicine composition for treating vitreous body and preparation method thereof |
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