CN103007571B - Alcohol-recyclable medicine extracting device and process thereof - Google Patents
Alcohol-recyclable medicine extracting device and process thereof Download PDFInfo
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- CN103007571B CN103007571B CN201210554045.4A CN201210554045A CN103007571B CN 103007571 B CN103007571 B CN 103007571B CN 201210554045 A CN201210554045 A CN 201210554045A CN 103007571 B CN103007571 B CN 103007571B
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Abstract
The invention discloses an alcohol-recyclable medicine extracting device and a process thereof. A liquid outlet of a first extracting tank is communicated with a liquid inlet of a first concentrator, and a thick liquid outlet of the first concentrator is communicated with a thick liquid inlet of an alcohol precipitation tank; a steam inlet is arranged at the lower portion of the alcohol precipitation tank, heated steam is directly fed into the alcohol precipitation tank through the steam inlet for heating precipitation, and alcohol steam after being evaporated enters into an alcohol condenser through an air outlet on the alcohol precipitation tank for condensation recycle. The device is suitable for extracting and purifying medicine active components in medicines through a solvent method and capable of recycling the alcohol contained in contamination precipitation during the purification.
Description
Technical field
The medicament extracting device and the technique thereof that the present invention relates to a kind of recyclable ethanol, belong to pharmaceutical equipment technical field.
Background technology
It is the process that the active constituents of medicine in the natural goodses such as animal, plant and mineral matter is extracted that medicine extracts, and wherein, the active constituents of medicine that plant contains has unique advantage to treatment disease, thereby the extraction of medicinal plants active component receives much concern.Medicine extraction method comprises solvent method, the way of distillation and sublimed method, and the applicable surface of latter two method is narrow, it is high to consume energy, thereby can not generally use the industrial extract by solvents medicines that adopt more.Solvent method is to utilize " similar mixing " principle, according to the character of active constituents of medicine, selects appropriate solvent to extract the method for active constituents of medicine, and common solvent has water, ethanol, acetone, benzene and benzinum etc.
Active constituents of medicine majority has hydrophily, when extracting hydrophilic medicament active component, often adopt these two kinds of water and ethanol nontoxic, pollute little and segregative solvent.As Chinese patent CN102552363A discloses a kind of method with alcohol extract mother chrysanthemum Chinese traditional medicine active component, after being pulverized, mother chrysanthemum raw material adds ethanolic solution, be placed in multi-function extractor, heating pressurised extraction 1-3 time, each 2h, extract merges filtration, obtain total extract, by total extract reduced pressure concentration, make after mother chrysanthemum concentrate high speed centrifugation, the dry Flos Chrysanthemi Indici extract that obtains.And for example, Chinese patent literature CN101711790A discloses a kind of method that water extracts wild walnut Chinese catalpa skin Chinese traditional medicine active component, Juglans mandshurica bark is added after 5 times of weight water soaking 24h, be heated to 100 ℃ of lasting 30min, filter, filter residue repeats to extract once, after twice filtrate is mixed and heating and concentrate.In ethanol extract in above-mentioned technology and water extract, except containing active constituents of medicine, also contain the impurity such as starch, polysaccharide and protein, the existence of these impurity can reduce the purity of active component in extract, thereby need to further remove above-mentioned impurity.
In order to remove above-mentioned impurity, conventionally with ethanol, extract is further purified, Chinese patent literature CN101045134A discloses a kind of preparation method who treats atherosclerotic pharmaceutical composition, first bulk drug is added and in multi-function extractor, heat decoction together with water, after filtration, obtain filtrate I, to adding water in the dregs of a decoction, decoct again once, filter and obtain filtrate II; Filtrate I, II are merged to heating in input dual-effect concentrator and be condensed into thick paste; Thick paste is inserted and in Alcohol-settling tank, is added ethanol cooling and stirring, get after standing supernatant after filtration, the concentrated and dry active component powder that obtains.Above-mentioned technology adds ethanol and in Alcohol-settling tank, carries out purifying in the water extract after concentrated, active constituents of medicine enters in the supernatant of Alcohol-settling tank, contamination precipitation is in Alcohol-settling tank bottom simultaneously, realized the object that extract is further purified, but still contain a large amount of ethanol in the precipitation of Alcohol-settling tank bottom, if directly precipitation is discarded, will certainly cause the waste of ethanol raw material.
Summary of the invention
Technical problem to be solved by this invention is that prior art extract is further purified and in rear remaining precipitation, still contains a large amount of ethanol and cannot be recycled, and has caused the waste of raw material; And then a kind of medicament extracting device and technique thereof that can reclaim ethanol in Alcohol-settling tank precipitation proposed.
For solving the problems of the technologies described above, the invention provides a kind of medicament extracting device of recyclable ethanol, comprise
The first extractor, is provided with solvent inlet and liquid outlet on described the first extractor;
The first inspissator, is provided with inlet and magma outlet on described the first inspissator, the liquid outlet of described the first extractor is connected with the inlet of described the first inspissator;
Alcohol-settling tank, is provided with magma import and supernatant outlet on described Alcohol-settling tank, the magma outlet of described the first inspissator is connected with the magma import of described Alcohol-settling tank;
On described Alcohol-settling tank, be provided with for heating the heater block of contamination precipitation in this tank;
Alcohol condenser, is provided with air inlet and liquid outlet on described alcohol condenser, on described Alcohol-settling tank, is provided with gas outlet, and the gas outlet of described Alcohol-settling tank is connected with the air inlet of described alcohol condenser.
Described heater block comprises that described steam inlet is arranged on the bottom of described Alcohol-settling tank for the steam inlet of vapours is provided in described Alcohol-settling tank.
Also comprise First Heat Exchanger, be provided with inlet and liquid outlet on described First Heat Exchanger, the liquid outlet of described First Heat Exchanger is connected with the solvent inlet of described the first extractor;
Medium storage tank, on described medium storage tank, be provided with inlet and liquid outlet, on described the first inspissator, be provided with media outlet, the media outlet of described the first inspissator is connected with the inlet of described medium storage tank, and the liquid outlet of described medium storage tank is connected with the inlet of described First Heat Exchanger.
Also comprise the second heat exchanger, on described the second heat exchanger, be provided with inlet, liquid outlet, air inlet and gas outlet, on described the first inspissator, be provided with gas outlet and air inlet, the gas outlet of described the first inspissator is connected with the air inlet of described the second heat exchanger, the gas outlet of described the second heat exchanger is connected with the air inlet of described the first inspissator, and the liquid outlet of described the second heat exchanger is connected with the inlet of described First Heat Exchanger.
Also comprise alcohol inspissator, be provided with inlet and magma outlet on described alcohol inspissator, the supernatant outlet of described Alcohol-settling tank and the inlet of described alcohol inspissator are connected.
Also comprise concentration detector, low alcohol storage tank, high alcohol storage tank and rectifying column, on described alcohol inspissator, be provided with the outlet of alcohol liquid, on described concentration detector, low alcohol storage tank and high alcohol storage tank, be provided with inlet and liquid outlet, on described rectifying column, be provided with inlet and the outlet of high alcohol; The inlet of described concentration detector is connected with the alcohol liquid outlet of described alcohol inspissator, the liquid outlet of described concentration detector is selected one by adjustable valve body and is connected with the inlet of described low alcohol storage tank and the inlet of described high alcohol storage tank, the liquid outlet of described low alcohol storage tank is connected with the inlet of described rectifying column, and the high alcohol outlet of described rectifying column is connected with the inlet of described high alcohol storage tank; The liquid outlet of described alcohol condenser is connected with the inlet of described low alcohol storage tank.
On described Alcohol-settling tank, be provided with the import of alcohol liquid, the liquid outlet of described high alcohol storage tank is connected with the alcohol liquid import of described Alcohol-settling tank.
Also comprise the second extractor, on described the second extractor, be provided with solvent inlet and liquid outlet, the inlet of the liquid outlet of described the second extractor and described alcohol inspissator is connected; The 3rd heat exchanger, is provided with inlet and liquid outlet on described the 3rd heat exchanger, and the liquid outlet of described the 3rd heat exchanger is connected with the solvent inlet of described the second extractor.
The liquid outlet of described the second heat exchanger is connected with the inlet of described the 3rd heat exchanger.
The liquid outlet of described high alcohol storage tank is connected with the inlet of described the 3rd heat exchanger.
On described the second extractor, be provided with the second return-flow system, described the second return-flow system comprises the second reflux condenser, the second filter element and the second reflux pump; On described the second reflux condenser, be provided with air inlet and gas outlet, on described the second filter element, be provided with inlet and liquid outlet, on described the second reflux pump, be provided with inlet and liquid outlet, the top of described the second extractor is provided with gas outlet and air inlet, bottom are provided with the outlet of slag liquid and clear liquid import; The gas outlet of described the second extractor is connected with the air inlet of described the second reflux condenser, and the gas outlet of described the second reflux condenser is connected with the air inlet of described the second extractor; The slag liquid outlet of described the second extractor is connected with the inlet of described the second filter element, the liquid outlet of described the second filter element is connected with the inlet of described the second reflux pump, and the liquid outlet of described the second reflux pump is connected with the clear liquid import of described the second extractor; Connect on the pipeline of the gas outlet of described the second reflux condenser and the air inlet of described the second extractor and be provided with a liquid outlet, this liquid outlet is connected with the inlet of described low alcohol storage tank.
The technique that described device extracts for medicine, comprises
Medicinal material and solvent are added in the first extractor and decocted, and the extract obtaining is inputted in the first inspissator concentrated, and the magma after concentrated is sent in Alcohol-settling tank and purified, and the liquid of purifying out is discharged and collected by supernatant outlet; With heater, heat remaining precipitation in described Alcohol-settling tank, the gas outlet by described Alcohol-settling tank after the ethanol evaporation in precipitation enters in alcohol condenser, and alcohol vapour is discharged and reclaimed by the liquid outlet of described alcohol condenser after condensation.
The present invention compares and has following beneficial effect with prior art scheme:
(1) medicament extracting device of recyclable ethanol of the present invention is provided with for heating the heater block of contamination precipitation in tank body on Alcohol-settling tank, and the alcohol condenser being connected with the gas outlet of Alcohol-settling tank; After purification process in Alcohol-settling tank completes, start to heat the precipitation in tank body by heater block, make the ethanol evaporation in precipitation become steam, alcohol vapour enters in alcohol condenser and carries out condensation after discharge the gas outlet on Alcohol-settling tank, and the ethanol liquid that condensation is got off is discharged and reclaimed by the liquid outlet of alcohol condenser.Avoid the ethanol in prior art Alcohol-settling tank precipitation cannot be recycled utilization, caused the problem of wastage of material.
(2) medicament extracting device of recyclable ethanol of the present invention, described heater block comprises that described steam inlet is arranged on the bottom of described Alcohol-settling tank for the steam inlet of vapours is provided in described Alcohol-settling tank.After purification process in Alcohol-settling tank finishes, by steam inlet, in Alcohol-settling tank, directly pass into hot water vapour, to heat the precipitation that contains ethanol in Alcohol-settling tank, make the ethanol after gasification enter in alcohol condenser condensation to reclaim ethanol by gas outlet.Passing into steam not only can be for providing enough moisture in Alcohol-settling tank, a large amount of ethanol evaporation are taken out of, and the mode of heating efficiency that steam directly contacts with precipitated phase is higher, and can homogeneous heating deposit surperficial, the ethanol that its surface has is evaporated in a large number.
(3) medicament extracting device of recyclable ethanol of the present invention, also comprises the medium storage tank being connected with the first inspissator and First Heat Exchanger respectively.In the situation that the solvent phase using in the cooling medium of the first inspissator and the first extractor is same, through the used cooling medium of the first inspissator, still there is certain temperature, being inputted First Heat Exchanger further inputs in the first extractor after heating again, can reduce bulk drug consumption to device external energy in decoction process, and effectively the used cooling medium of reuse, has saved cost.
(4) medicament extracting device of recyclable ethanol of the present invention, also comprise the second heat exchanger, on described the second heat exchanger, be provided with inlet, liquid outlet, air inlet and gas outlet, on described the first inspissator, be provided with gas outlet and air inlet, the gas outlet of described the first inspissator is connected with the air inlet of described the second heat exchanger, the gas outlet of described the second heat exchanger is connected with the air inlet of described the first inspissator, and the liquid outlet of described the second heat exchanger is connected with the inlet of described First Heat Exchanger.Utilize the steam heat in the first inspissator to heat the solvent in the second heat exchanger, after further heating in the solvent input First Heat Exchanger after heating, the solvent as the first extractor is used again afterwards, can reduce medicinal material and decoct the consumption to external energy in leaching process, effectively utilized the heat of steam in the first inspissator, and the steam after heat-shift also can be flow back in the first inspissator by the second heat exchanger, for final collection and treatment.
(5) medicament extracting device of recyclable ethanol of the present invention, also comprises concentration detector, low alcohol storage tank, high alcohol storage tank and rectifying column.The liquid outlet of described high alcohol storage tank is connected with the alcohol liquid import of described Alcohol-settling tank, the inlet of described the 3rd heat exchanger.The alcoholic solvent of collecting out in alcohol inspissator is after concentration detector detects, and high concentration alcohol deposits in high alcohol storage tank, and low concentration alcohol deposits in low alcohol storage tank; Low concentration alcohol in low alcohol storage tank is after rectifying column fractionation, and the high concentration alcohol unloading fractionating out enters in high alcohol storage tank.Alcohol in high alcohol storage tank can be done solvent use by direct reuse in the second extractor and Alcohol-settling tank, has reduced and has installed right total alcohol consumption, has reduced pollution, has saved cost.
(6) medicament extracting device of recyclable ethanol of the present invention, connects on the pipeline of the gas outlet of described the second reflux condenser and the air inlet of described the second extractor and is provided with a liquid outlet, and this liquid outlet is connected with the inlet of described low alcohol storage tank.After leaching process finishes, the dregs of a decoction in heating the second extractor, enter condensation in the second reflux condenser after alcohol liquid evaporation wherein, are introduced in low alcohol storage tank and are preserved afterwards, thereby reclaimed a large amount of alcohol liquid in the extractor dregs of a decoction by pipeline, have saved cost of material.
Accompanying drawing explanation
For content of the present invention is more easily understood, the present invention is further detailed content of the present invention with the specific embodiment by reference to the accompanying drawings;
Fig. 1 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 1;
Fig. 2 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 2;
Fig. 3 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 3;
Fig. 4 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 4;
Fig. 5 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 5;
Fig. 6 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 6;
Fig. 7 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 7;
Fig. 8 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 8;
Fig. 9 is the flow chart of the medicament extracting device of recyclable ethanol described in the embodiment of the present invention 9.
The specific embodiment
embodiment 1
Described in the present embodiment, the medicament extracting device of recyclable ethanol as shown in Figure 1, comprises the first extractor, on described the first extractor, is provided with solvent inlet and liquid outlet; The first inspissator, is provided with inlet and magma outlet on described the first inspissator, the liquid outlet of described the first extractor is connected with the inlet of described the first inspissator; Alcohol-settling tank, is provided with magma import and supernatant outlet on described Alcohol-settling tank, the magma outlet of described the first inspissator is connected with the magma import of described Alcohol-settling tank;
On described Alcohol-settling tank, be provided with for heating the heater block of contamination precipitation in this tank body; Alcohol condenser, is provided with air inlet and liquid outlet on described alcohol condenser, on described Alcohol-settling tank, is provided with gas outlet, and the gas outlet of described Alcohol-settling tank is connected with the air inlet of described alcohol condenser.
When said apparatus is used, medicinal material and solvent are added in the first extractor and decocted, the extract obtaining is inputted in the first inspissator concentrated, and the magma after concentrated is sent in Alcohol-settling tank and purified, and the liquid of purifying out is discharged and collected by supernatant outlet; With heater block, heat remaining precipitation in described Alcohol-settling tank, the gas outlet by described Alcohol-settling tank after the ethanol evaporation in precipitation enters in alcohol condenser, and alcohol vapour is discharged and reclaimed by the liquid outlet of described alcohol condenser after condensation.
embodiment 2
The present embodiment is on the basis of above-described embodiment, and as shown in Figure 2, further heater block is set to for steam inlet and the vapours source of vapours are provided in described Alcohol-settling tank, and described steam inlet is arranged on the bottom of described Alcohol-settling tank.By steam inlet, directly the vapours in vapours source is passed in Alcohol-settling tank, to heat the remaining precipitation of Alcohol-settling tank, the ethanol evaporation condensation of being convenient in precipitation is reclaimed; Wherein the vapours in the present embodiment is 130 ℃ of following water vapours.
Described in the present embodiment, the medicament extracting device of recyclable ethanol also comprises the first extract storage tank, for storing by the first extractor output, further concentrated extract is not also able to do in time, on described the first extract storage tank, be provided with inlet and liquid outlet, the liquid outlet of described the first extractor is connected with the inlet of described the first extract storage tank, and the liquid outlet of described the first extract storage tank is connected with the inlet of described the first inspissator.
First Heat Exchanger, is provided with inlet and liquid outlet on described First Heat Exchanger, the liquid outlet of described First Heat Exchanger is connected with the solvent inlet of described the first extractor, and First Heat Exchanger is conveyed into the solvent of the first extractor for preheating.
Medium storage tank, on described medium storage tank, be provided with inlet and liquid outlet, on described the first inspissator, be provided with media outlet, the media outlet of described the first inspissator is connected with the inlet of described medium storage tank, and described medium storage tank is used for storing the used cooling medium of the first inspissator; The liquid outlet of described medium storage tank is connected with the inlet of described First Heat Exchanger, the solvent phase using in the cooling medium of the first inspissator and the first extractor, is directly delivered to after First Heat Exchanger heating the used cooling medium with uniform temperature in the first inspissator for the first extractor simultaneously.
embodiment 3
The present embodiment is on the basis of above-described embodiment, also comprise as shown in Figure 3 the second heat exchanger, on described the second heat exchanger, be provided with inlet, liquid outlet, air inlet and gas outlet, on described the first inspissator, be provided with gas outlet and air inlet, the gas outlet of described the first inspissator is connected with the air inlet of described the second heat exchanger, the gas outlet of described the second heat exchanger is connected with the air inlet of described the first inspissator, and the liquid outlet of described the second heat exchanger is connected with the inlet of described First Heat Exchanger.After the second heat exchanger utilizes the vapours in the first inspissator that cold solvent is heated, solvent is sent in the first extractor and is used through the further heating of First Heat Exchanger; After the used vapours of the second heat exchanger is cooling, again send back in the first inspissator, for the solvent in recovered steam.
embodiment 4
The present embodiment is on the basis of above-described embodiment, as shown in Figure 4, also comprise low alcohol storage tank, on described low alcohol storage tank, be provided with inlet, the liquid outlet of described alcohol condenser is connected with the inlet of described low alcohol storage tank, and the ethanol being flowed out by alcohol condenser liquid outlet is directly sent in low alcohol storage tank and preserved;
Alcohol inspissator, on described alcohol inspissator, be provided with inlet and magma outlet, the supernatant outlet of described Alcohol-settling tank and the inlet of described alcohol inspissator are connected, and the medicine feed concentration after being purified by Alcohol-settling tank is lower, need enter in alcohol inspissator and again concentrate, to obtain the medicine of high concentration;
Supernatant storage tank, on described supernatant storage tank, be provided with inlet and liquid outlet, the supernatant outlet of described Alcohol-settling tank and the inlet of described supernatant storage tank are connected, the liquid outlet of described supernatant storage tank is connected with the inlet of described alcohol inspissator, by the medicine feed liquid after Alcohol-settling tank is purified, had little time to enter in alcohol inspissator when concentrated, deposit in supernatant storage tank and preserve.
embodiment 5
The present embodiment is on the basis of above-described embodiment, as shown in Figure 5, also comprise concentration detector, high alcohol storage tank and rectifying column, on described alcohol inspissator, be provided with the outlet of alcohol liquid, on described low alcohol storage tank, be provided with liquid outlet, on described concentration detector and high alcohol storage tank, be provided with inlet and liquid outlet, on described rectifying column, be provided with inlet and the outlet of high alcohol; The inlet of described concentration detector is connected with the alcohol liquid outlet of described alcohol inspissator, the liquid outlet of described concentration detector is selected one by adjustable valve body and is connected with the inlet of described low alcohol storage tank and the inlet of described high alcohol storage tank, the liquid outlet of described low alcohol storage tank is connected with the inlet of described rectifying column, and the high alcohol outlet of described rectifying column is connected with the inlet of described high alcohol storage tank; The alcohol liquid being reclaimed by alcohol inspissator after concentration detector detects, by application valve body by high concentration alcohol liquid send in high alcohol storage tank, low concentration alcohol liquid sends in low alcohol storage tank; The high concentration alcohol of alcohol liquid in low alcohol storage tank after rectifying column rectifying separation is sent in high alcohol storage tank and is preserved.
On described Alcohol-settling tank, be provided with the import of alcohol liquid, the liquid outlet of described high alcohol storage tank is connected with the alcohol liquid import of described Alcohol-settling tank, and the high concentration alcohol liquid in high alcohol storage tank can be directly used as the solvent of Alcohol-settling tank.
embodiment 6
The present embodiment, on the basis of above-described embodiment, as shown in Figure 6, also comprises the second extractor, on described the second extractor, is provided with solvent inlet and liquid outlet; The second extract storage tank, on described the second extract storage tank, be provided with inlet and liquid outlet, the inlet of the liquid outlet of described the second extractor and described the second extract storage tank is connected, and the liquid outlet of described the second extract storage tank is connected with the inlet of described alcohol inspissator; The 3rd heat exchanger, is provided with inlet and liquid outlet on described the 3rd heat exchanger, and the liquid outlet of described the 3rd heat exchanger is connected with the solvent inlet of described the second extractor; The liquid outlet of described the second heat exchanger is connected with the inlet of described the 3rd heat exchanger.By when the second extractor, the second extractor storage tank and the 3rd heater being set, can realizing carry out medicine extraction in the first extractor, in the second extractor, carry out the process of alcohol extracting medicine, thereby improved the efficiency that medicine extracts; The second heat exchanger also can be used for heating cold alcohol liquid, and the alcohol liquid after heating is sent into the second extractor and used as solvent after the 3rd heater further heats.
embodiment 7
The present embodiment is on the basis of above-described embodiment, and as shown in Figure 7, the liquid outlet of described high alcohol storage tank is connected with the inlet of described the 3rd heat exchanger, and the solvent that the high concentration alcohol liquid after recovery can be used as the second extractor after the 3rd heater heating is used.
embodiment 8
The present embodiment, on the basis of above-described embodiment, as shown in Figure 8, is provided with the second return-flow system on described the second extractor, and described the second return-flow system comprises the second reflux condenser, the second filter element and the second reflux pump; On described the second reflux condenser, be provided with air inlet and gas outlet, on described the second filter element, be provided with inlet and liquid outlet, on described the second reflux pump, be provided with inlet and liquid outlet, the top of described the second extractor is provided with gas outlet and air inlet, bottom are provided with the outlet of slag liquid and clear liquid import; The gas outlet of described the second extractor is connected with the air inlet of described the second reflux condenser, and the gas outlet of described the second reflux condenser is connected with the air inlet of described the second extractor; The slag liquid outlet of described the second extractor is connected with the inlet of described the second filter element, the liquid outlet of described the second filter element is connected with the inlet of described the second reflux pump, and the liquid outlet of described the second reflux pump is connected with the clear liquid import of described the second extractor; The medicine steam of the second extractor internal upper part is got back in tank again after by the second reflux condenser condensation, so that medicine steam refluxes; Meanwhile, the medicine feed liquid of extractor bottom is transmitted back in extractor by the second reflux pump after the second filter element filters, and makes the medicine feed liquid in tank also obtain backflow; The medicament active composition of backflow by medicine steam and medicine feed liquid in can medicinal material dissolves more in solvent, finally obtains the drug extract of high concentration.
Connect on the pipeline of the gas outlet of described the second reflux condenser and the air inlet of described the second extractor and be provided with a liquid outlet, this liquid outlet is connected with the inlet of described low alcohol storage tank; Drug extract in the first extractor still contains a large amount of available alcohol after deriving in the dregs of a decoction of tank base, the heating dregs of a decoction evaporate by the second reflux condenser condensation alcohol wherein, and the alcohol liquid of condensation is sent into low alcohol storage tank and preserved.
On described the first extractor, be provided with the first return-flow system, described the first return-flow system comprises the first reflux condenser, the first filter element and the first reflux pump; On described the first reflux condenser, be provided with air inlet and gas outlet, on described the first filter element, be provided with inlet and liquid outlet, on described the first reflux pump, be provided with inlet and liquid outlet, the top of described the first extractor is provided with gas outlet and air inlet, bottom are provided with the outlet of slag liquid and clear liquid import; The gas outlet of described the first extractor is connected with the air inlet of described the first reflux condenser, and the gas outlet of described the first reflux condenser is connected with the air inlet of described the first extractor; The slag liquid outlet of described the first extractor is connected with the inlet of described the first filter element, the liquid outlet of described the first filter element is connected with the inlet of described the first reflux pump, and the liquid outlet of described the first reflux pump is connected with the clear liquid import of described the first extractor.In like manner, the first return-flow system can make medicine steam and the medicine feed liquid in the first extractor reflux fully, thereby more medicament active composition in medicinal material is dissolved into solvent, finally obtains the drug extract of high concentration.
embodiment 9
The present embodiment is on the basis of above-described embodiment, as shown in Figure 9, also comprise cooling medium collecting tank, on described cooling medium collecting tank, be provided with inlet, on described the first extractor, First Heat Exchanger, the first inspissator, the second extractor, the 3rd heat exchanger, alcohol inspissator and rectifying column, be provided with cooling medium outlet; The cooling medium outlet of described the first extractor, First Heat Exchanger, the first inspissator, the second extractor, the 3rd heat exchanger, alcohol inspissator and rectifying column is all connected with the inlet of described cooling medium collecting tank.The cooling medium of above-mentioned heat transmission equipment is identical, and the most used cooling medium is sent into the preservation of cooling medium collecting tank.
The first extractor in above-described embodiment, the first extract storage tank, the first inspissator, First Heat Exchanger, the second heat exchanger, Alcohol-settling tank, supernatant storage tank, the second extractor, the second extract storage tank, alcohol inspissator, the 3rd heat exchanger, rectifying column, alcohol condenser and other storage tanks and condenser etc. are commercially available equipment.
Although the present invention has carried out detailed elaboration by above-mentioned specific embodiment to it; but; those skilled in the art should be understood that any form that does not exceed claim protection domain made on this basis and the variation of details, all belong to invention which is intended to be protected.
Claims (1)
1. a medicament extracting device for recyclable ethanol, comprises
The first extractor, is provided with solvent inlet and liquid outlet on described the first extractor;
The first inspissator, is provided with inlet and magma outlet on described the first inspissator, the liquid outlet of described the first extractor is connected with the inlet of described the first inspissator;
Alcohol-settling tank, is provided with magma import and supernatant outlet on described Alcohol-settling tank, the magma outlet of described the first inspissator is connected with the magma import of described Alcohol-settling tank;
It is characterized in that,
On described Alcohol-settling tank, be provided with for heating the heater block of contamination precipitation in this tank;
Alcohol condenser, is provided with air inlet and liquid outlet on described alcohol condenser, on described Alcohol-settling tank, is provided with gas outlet, and the gas outlet of described Alcohol-settling tank is connected with the air inlet of described alcohol condenser;
First Heat Exchanger, is provided with inlet and liquid outlet on described First Heat Exchanger, the liquid outlet of described First Heat Exchanger is connected with the solvent inlet of described the first extractor;
Medium storage tank, on described medium storage tank, be provided with inlet and liquid outlet, on described the first inspissator, be provided with media outlet, the media outlet of described the first inspissator is connected with the inlet of described medium storage tank, and the liquid outlet of described medium storage tank is connected with the inlet of described First Heat Exchanger.
2. device according to claim 1, is characterized in that, described heater block comprises that described steam inlet is arranged on the bottom of described Alcohol-settling tank for the steam inlet of vapours is provided in described Alcohol-settling tank.
3. device according to claim 1 and 2, it is characterized in that, also comprise the second heat exchanger, on described the second heat exchanger, be provided with inlet, liquid outlet, air inlet and gas outlet, on described the first inspissator, be provided with gas outlet and air inlet, the gas outlet of described the first inspissator is connected with the air inlet of described the second heat exchanger, the gas outlet of described the second heat exchanger is connected with the air inlet of described the first inspissator, and the liquid outlet of described the second heat exchanger is connected with the inlet of described First Heat Exchanger.
4. device according to claim 3, is characterized in that, also comprises alcohol inspissator, is provided with inlet and magma outlet on described alcohol inspissator, and the supernatant outlet of described Alcohol-settling tank and the inlet of described alcohol inspissator are connected.
5. device according to claim 4, it is characterized in that, also comprise concentration detector, low alcohol storage tank, high alcohol storage tank and rectifying column, on described alcohol inspissator, be provided with the outlet of alcohol liquid, on described concentration detector, low alcohol storage tank and high alcohol storage tank, be provided with inlet and liquid outlet, on described rectifying column, be provided with inlet and the outlet of high alcohol; The inlet of described concentration detector is connected with the alcohol liquid outlet of described alcohol inspissator, the liquid outlet of described concentration detector is selected one by adjustable valve body and is connected with the inlet of described low alcohol storage tank and the inlet of described high alcohol storage tank, the liquid outlet of described low alcohol storage tank is connected with the inlet of described rectifying column, and the high alcohol outlet of described rectifying column is connected with the inlet of described high alcohol storage tank; The liquid outlet of described alcohol condenser is connected with the inlet of described low alcohol storage tank.
6. device according to claim 5, is characterized in that, is provided with the import of alcohol liquid on described Alcohol-settling tank, and the liquid outlet of described high alcohol storage tank is connected with the alcohol liquid import of described Alcohol-settling tank.
7. according to the device described in claim 4 or 5 or 6, it is characterized in that, also comprise the second extractor, on described the second extractor, be provided with solvent inlet and liquid outlet, the inlet of the liquid outlet of described the second extractor and described alcohol inspissator is connected; The 3rd heat exchanger, is provided with inlet and liquid outlet on described the 3rd heat exchanger, and the liquid outlet of described the 3rd heat exchanger is connected with the solvent inlet of described the second extractor.
8. device according to claim 7, is characterized in that, the liquid outlet of described the second heat exchanger is connected with the inlet of described the 3rd heat exchanger.
9. device according to claim 8, is characterized in that, the liquid outlet of described high alcohol storage tank is connected with the inlet of described the 3rd heat exchanger.
10. device according to claim 8 or claim 9, is characterized in that, on described the second extractor, be provided with the second return-flow system, described the second return-flow system comprises the second reflux condenser, the second filter element and the second reflux pump; On described the second reflux condenser, be provided with air inlet and gas outlet, on described the second filter element, be provided with inlet and liquid outlet, on described the second reflux pump, be provided with inlet and liquid outlet, the top of described the second extractor is provided with gas outlet and air inlet, bottom are provided with the outlet of slag liquid and clear liquid import; The gas outlet of described the second extractor is connected with the air inlet of described the second reflux condenser, and the gas outlet of described the second reflux condenser is connected with the air inlet of described the second extractor; The slag liquid outlet of described the second extractor is connected with the inlet of described the second filter element, the liquid outlet of described the second filter element is connected with the inlet of described the second reflux pump, and the liquid outlet of described the second reflux pump is connected with the clear liquid import of described the second extractor; Connect on the pipeline of the gas outlet of described the second reflux condenser and the air inlet of described the second extractor and be provided with a liquid outlet, this liquid outlet is connected with the inlet of described low alcohol storage tank.
The technique that described in 11. claims 1, device extracts for medicine, comprises
Medicinal material and solvent are added in the first extractor and decocted, and the extract obtaining is inputted in the first inspissator concentrated, and the magma after concentrated is sent in Alcohol-settling tank and purified, and the liquid of purifying out is discharged and collected by supernatant outlet; With heater, heat remaining precipitation in described Alcohol-settling tank, the gas outlet by described Alcohol-settling tank after the ethanol evaporation in precipitation enters in alcohol condenser, and alcohol vapour is discharged and reclaimed by the liquid outlet of described alcohol condenser after condensation.
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| CN103007571B true CN103007571B (en) | 2014-09-10 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106256338A (en) * | 2016-07-25 | 2016-12-28 | 湖北梦阳药业股份有限公司 | A kind of raw white kalgan lamb skin takes liquid production line |
| CN107961560A (en) * | 2017-11-28 | 2018-04-27 | 山东华品生物科技有限公司 | Chinese traditional medicine purification device and method |
| CN108379873B (en) * | 2018-04-11 | 2020-12-08 | 华东理工大学 | Device for recovering ethanol in traditional Chinese medicine extraction process |
| CN111905404A (en) * | 2020-09-02 | 2020-11-10 | 上海复旦复华药业有限公司 | Method for removing residual ethanol from tripterygium wilfordii alcohol extraction residues |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1070341A (en) * | 1992-07-25 | 1993-03-31 | 青海省第三制药厂 | The production method of the extraction process of ZANGYINCHEN effective ingredient, equipment and ZANGYINCHEN tablet |
| CN101045134A (en) * | 2007-04-26 | 2007-10-03 | 江苏南星药业有限责任公司 | Method for preparing medicine to treat atherosclerosis |
| CN201558315U (en) * | 2009-12-22 | 2010-08-25 | 上海悦胜芜湖药业有限公司 | Preparation system of Chinese medicine of Yupingfeng extract ointment |
| CN102527066A (en) * | 2012-02-23 | 2012-07-04 | 李晓云 | Multifunctional hot reflux extracting and concentrating unit |
| CN202315399U (en) * | 2011-11-15 | 2012-07-11 | 三门峡广宇生物制药有限公司 | Ethanol extraction tank |
-
2012
- 2012-12-19 CN CN201210554045.4A patent/CN103007571B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1070341A (en) * | 1992-07-25 | 1993-03-31 | 青海省第三制药厂 | The production method of the extraction process of ZANGYINCHEN effective ingredient, equipment and ZANGYINCHEN tablet |
| CN101045134A (en) * | 2007-04-26 | 2007-10-03 | 江苏南星药业有限责任公司 | Method for preparing medicine to treat atherosclerosis |
| CN201558315U (en) * | 2009-12-22 | 2010-08-25 | 上海悦胜芜湖药业有限公司 | Preparation system of Chinese medicine of Yupingfeng extract ointment |
| CN202315399U (en) * | 2011-11-15 | 2012-07-11 | 三门峡广宇生物制药有限公司 | Ethanol extraction tank |
| CN102527066A (en) * | 2012-02-23 | 2012-07-04 | 李晓云 | Multifunctional hot reflux extracting and concentrating unit |
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