CN103006465A - Delousing and acarid expelling preparation for animals - Google Patents
Delousing and acarid expelling preparation for animals Download PDFInfo
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- CN103006465A CN103006465A CN 201210511709 CN201210511709A CN103006465A CN 103006465 A CN103006465 A CN 103006465A CN 201210511709 CN201210511709 CN 201210511709 CN 201210511709 A CN201210511709 A CN 201210511709A CN 103006465 A CN103006465 A CN 103006465A
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Abstract
The invention discloses a delousing and acarid expelling preparation for animals. The delousing and acarid expelling preparation comprises the following components in parts by weight: 0.03 to 0.05 part of pyrethrin, 0.15 to 0.25 part of piperonyl butoxide, 0.5 to 1 part of hydrogenated cocoglycerides, 0.00012 part of Kathon (methyl chloride isothiazolinone and methyl isothiazolinone) and 70 to 85 parts of deionized water. According to the delousing and acarid expelling preparation, pollution-free natural pyrethrin is used as an active substance; in a process of bathing a pet, the pyrethrin can greatly expel fleas and louses and can quickly palsy insects and make acarids lose the eating capacity, so that delousing and acarid expelling effects can be achieved; and after being used, the delousing and acarid expelling preparation is not retained, so that side effects on people and the pet are avoided.
Description
Technical field
The present invention relates to a kind of animal and drive the demodicid mite preparation with removing lice.
Background technology
Along with the acceleration of Chinese society expanding economy and urbanization process, the upsurge of raising pets is surging forward in China city.But the thing followed is pet body is easy to parasitic various insect outward, such as louse, acarid and flea etc., sometimes also can carry the kind pathogenic bacteria, and the harm house pet is healthy, also may cause the cross infection of people, animal disease.
At present, house pet is washed and protects main employing shampoo both at home and abroad, wherein mainly adopt international too controversial surfactant: (1) 6501 cocos nucifera oil diglycollic amide is used as detergent, foaming promoter, thickening agent, this raw material may produce nitrous acid, cause producing in human body inferior ammonium nitrate, inferior ammonium nitrate is one of most important chemical carcinogen; (2) mainly as cleaning agent, thickening agent and reduction system zest, this raw material is introduced the by-product monoxone to CAB cocos nucifera oil acyl hydroxypropyl betanin in process of production, and monoxone has severe toxicity.
Therefore, existing house pet, and the animal removing lice such as poultry to drive the demodicid mite kind more single, and mostly contain poisonous and harmful substance.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of natural, plant, safety of the preparation take natural pyrethrum as raw material, the house pet of environmental protection to drive the demodicid mite preparation with removing lice.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of animal drives the demodicid mite preparation with removing lice, comprises following component according to weight percent meter:
Pyrethrin, 0.03 part-0.05 part;
Piperonyl butoxide, 0.15 part-0.25 part;
Cocos nucifera oil glyceride, 0.5 part-1 part;
KF88 (methylchloroisothiazandnone and Methylisothiazolinone), 0.00012 part;
Deionized water, 70 parts-85 parts.
Above-mentioned animal drives the demodicid mite preparation with removing lice and is made into shampoo.Animal drives the demodicid mite shampoo with removing lice, also comprises following material:
Polyoxyethylene lauryl ether sodium sulfate, 10 parts-15 parts;
Cocos nucifera oil acyl hydroxy sulfo lycine, 5 parts-8 parts;
Coconut monoethanol amide, 1.2 parts-2 parts;
SAS, 2 parts-3 parts;
Sodium lauryl sulphate, 1 part-3 parts;
Alkyl polyglucoside, 2 parts-3 parts;
Glycol distearate, 1 part-2 parts;
Polyquaternary ammonium salt-7,1 parts-1.5 parts;
Polyquaternium-10,0.1 part-0.3 part;
Propylene glycol, 0.5 part-1 part;
The guar gum hydroxypropyl-trimethyl ammonium chloride, 0.1 part-0.3 part;
Citric acid, 0.2 part-0.5 part;
Essence, 0.3 part-0.5 part.
Above-mentioned animal drives the demodicid mite preparation with removing lice and is made into spray or propellant, also comprises following material:
Cremophor RH40,2 parts-3 parts;
Tween 20,2 parts-3 parts;
The oil-soluble azone, 0.1 part-0.5 part;
Disodiumedetate, 0.1 part-0.2 part.
It is active substance that the present invention adopts precious internationally recognized safest pollution-free natural pyrethrin, and natural pyrethrum extracts from Pyrethrum.
Natural pyrethrum has the extremely strong effect of driveing to flea and louse, can benumb rapidly and knock down insecticide, thereby and can make acarid lose the effect that the feed ability plays the expeling acarid, simultaneously, adopt gentle sterilization formulation, can effectively alleviate scytitis, eliminate fungus-caused various animal skin problem, it is glossy that the special moisturizing composition that adds and water solublity lanoline can make hair moisten.
Natural pyrethrum sees that light slowly resolves into water and CO in the shampoo of the present invention
2, therefore with use such as the shampoo of its preparation and spray afterwards noresidue the people doted on have no side effect, be internationally recognized safest pollution-free natural insecticide.
Because pyrethrin is comprised of the six kinds of materials with insecticidal activity that extract in the pyrethrum flowers, so good disinsection effect, is difficult for developing immunity to drugs.Pyrethrin has the effect of paralysis insecticide nervus centralis, and fast for killing insects by touching agent so parasite killing speed, fatality rate is high, and working concentration is low.Pyrethrin has parasite killing and environmental protection two large functions, and any chemical insecticide can't be compared.
The specific embodiment
Embodiment 1
A kind of animal drives the demodicid mite preparation with removing lice, comprises following component according to weight percent meter:
Pyrethrin, 0.03 part-0.05 part;
Piperonyl butoxide, 0.15 part-0.25 part;
Cocos nucifera oil glyceride, 0.5 part-1 part;
KF88 (methylchloroisothiazandnone and Methylisothiazolinone), 0.00012 part;
Deionized water, 70 parts-85 parts.
Embodiment 2
A kind of animal drives the demodicid mite shampoo with removing lice, comprises following component according to weight percent meter:
Pyrethrin, 0.03 part-0.05 part;
Piperonyl butoxide, 0.15 part-0.25 part;
Cocos nucifera oil glyceride, 0.5 part-1 part;
KF88 (methylchloroisothiazandnone and Methylisothiazolinone), 0.00012 part;
Deionized water, 70 parts-85 parts;
Polyoxyethylene lauryl ether sodium sulfate, 10 parts-15 parts;
Cocos nucifera oil acyl hydroxy sulfo lycine, 5 parts-8 parts;
Coconut monoethanol amide, 1.2 parts-2 parts;
SAS, 2 parts-3 parts;
Sodium lauryl sulphate, 1 part-3 parts;
Alkyl polyglucoside, 2 parts-3 parts;
Glycol distearate, 1 part-2 parts;
Polyquaternary ammonium salt-7,1 parts-1.5 parts;
Polyquaternium-10,0.1 part-0.3 part;
Propylene glycol, 0.5 part-1 part;
The guar gum hydroxypropyl-trimethyl ammonium chloride, 0.1 part-0.3 part;
Citric acid, 0.2 part-0.5 part;
Essence, 0.3 part-0.5 part.
Embodiment 3
A kind of animal drives demodicid mite spray or propellant with removing lice, comprises following component according to weight percent meter:
Pyrethrin, 0.03 part-0.05 part;
Piperonyl butoxide, 0.15 part-0.25 part;
Cocos nucifera oil glyceride, 0.5 part-1 part;
KF88 (methylchloroisothiazandnone and Methylisothiazolinone), 0.00012 part;
Deionized water, 70 parts-85 parts;
Cremophor RH40,2 parts-3 parts;
Tween 20,2 parts-3 parts;
The oil-soluble azone, 0.1 part-0.5 part;
Disodiumedetate, 0.1 part-0.2 part.
Embodiment 4
The new veterinary drug development of Qingdao Agricultural University is driven the demodicid mite shampoo with Research on Safety Assessment to removing lice of the present invention the vermiontic prevention effect of house pet has been carried out experimental study.
Result of the test is reported as follows:
1 material
1.1 given the test agent
Removing lice drives the demodicid mite shampoo and is provided by Qingdao Magic Pet Products Co., Ltd., and commercially available similar import shampoo for pets is product in contrast.
The apparatuses such as Olympus biological microscope, anatomical lens, beaker, microscope slide, coverslip, operating scissors, plate, stopwatch.
1.2 experimental animal
Clinical definite infects vermiontic domestic pets dog, the cats such as louse, flea totally 30 examples.
2 methods
2.1 common epizoa killing effect is observed
Infection there is the pet dog of louse, flea, uses for after the examination shampoo, observe its clinical symptoms in 24-72h, to judge the epizoa infection conditions.Take galley proof, the ectozoic kind of microscopy and quantity thereof are chosen polypide, the microscopy survival condition, stiff without activeness person declare do dead.
Use rear seven days difference of appointment property Ah Bai scraping pathological material of disease microscopy to making a definite diagnosis the house pet that suffers from acaricide, observe the active situation of acarid and the clinical symptoms of house pet thereof.
The criterion of shampoo for pets insect esexpeling test effect:
Cure: after the course for the treatment of, all clinical symptom disappearance, it is normal that pet activity recovers, and checks to have no pathogen and pathogen Excreta.
Effectively: after the course for the treatment of, all clinical symptom reliefs, but do not return to the premorbid state, check that pathogen and the excremental quantity of pathogen obviously reduce.
Invalid: after the course for the treatment of, clinical symptoms is without significant change even increase the weight of, and checks that pathogen and pathogen Excreta have no minimizing.
2.2 killing in vitro epizoa test
To place plate from the epizoa that the house pet body surface captures, will be divided into sample for the examination shampoo simultaneously, be positioned in the plate rubber belt sealing plate.Under 22 ℃ of the room temperatures, under anatomical lens, per hour observe 1 time, behind the Continuous Observation 6h, observe 1 time to 48h every 6h, observe shampoo for pets to the effect of polypide.Matched group does not use shampoo.Be judged to death so that parasite limbs and claw are motionless and stiff.
3 testing results
3.1 to common epizoa killing effect
Choose the pet dog that infects clinically louse, holy ectoparasite disease, cat totally 25 examples.Case ectoparasite disease Clinical symptoms is obvious, and animal shows as dysphoria, scratches where it itches, scratches everywhere and rub, and checks that Rhizoma Imperatae section can find louse, holy Excreta.
Use for the examination shampoo, behind 24h, observe its clinical response, 19 pet dog clinical symptom disappearance wherein, without scratching where it itches phenomenon, diet is had a rest and is all recovered normal, give pet bathing after 24h check that again Rhizoma Imperatae section does not find louse, flea Excreta; 3 pet dog clinical symptoms obviously alleviate, and diet is had a rest basic recovery normally, and the rear 24h that has a bath checks and finds only to have a small amount of louse, holy Excreta; 3 pet dog are used for clinical symptoms after the examination shampoo without significant change.Drive away louse, flea effect relatively with the contrast of selling on the market with shampoo, contrast is 78% with the clinical case cure rate of shampoo, effective percentage 88%, and the trial product effect is suitable with being subjected to.
Choose and infect clinically the ectozoic pet dog of demodicid mite class, cat totally 5 examples.Infect around the house pet eye socket of acaricide, the nose depilation obviously, pigementation appears in part house pet depilation position skin.Take galley proof, visible acarid live body behind the microscopy.Use takes the galley proof microscopy to observe acarid activity situation behind 7d for the examination shampoo again, obviously reduces and reduction before finding acarid quantity, activity and using shampoo, shows for the examination shampoo good to the clinical result of use of house pet acaricide.
3.2 killing in vitro epizoa effect
Amount to 15 from clinical onset case body surface crawl louse, flea, will be wherein 10 place plate, simultaneously shampoo for pets is divided into sample, also place in the plate, be made as experimental group: other 5 place in the plate, and group is used respectively the rubber belt sealing plate in contrast, under 22 ℃ of the room temperatures, in dissecting Microscopic observation.Criterion: the motionless Bing Only of polypide limbs and claw directly is judged to death.
Test group Continuous Observation 5h, louse, flea mobility descend in the plate, and all dead behind the 12h, limbs are stiff, and without movable, limbs shrink agglomerating subsequently; 5 parasite 12h are showed no unusually in the contrast plate, and are movable normal.The in vitro tests result shows that tested shampoo for pets is respond well to expeling louse, holy epizoa.
Claims (5)
1. an animal drives the demodicid mite preparation with removing lice, it is characterized in that: comprise following component according to the parts by weight meter:
Pyrethrin, 0.03 part-0.05 part;
Piperonyl butoxide, 0.15 part-0.25 part;
Cocos nucifera oil glyceride, 0.5 part-1 part;
KF88 (methylchloroisothiazandnone and Methylisothiazolinone), 0.00012 part;
Deionized water, 70 parts-85 parts.
2. animal according to claim 1 drives the demodicid mite preparation with removing lice, it is characterized in that: also comprise following material:
Polyoxyethylene lauryl ether sodium sulfate, 10 parts-15 parts;
Cocos nucifera oil acyl hydroxy sulfo lycine, 5 parts-8 parts;
Coconut monoethanol amide, 1.2 parts-2 parts;
SAS, 2 parts-3 parts;
Sodium lauryl sulphate, 1 part-3 parts;
Alkyl polyglucoside, 2 parts-3 parts;
Glycol distearate, 1 part-2 parts;
Polyquaternary ammonium salt-7,1 parts-1.5 parts;
Polyquaternium-10,0.1 part-0.3 part;
Propylene glycol, 0.5 part-1 part;
The guar gum hydroxypropyl-trimethyl ammonium chloride, 0.1 part-0.3 part;
Citric acid, 0.2 part-0.5 part;
Essence, 0.3 part-0.5 part.
3. animal according to claim 2 drives the demodicid mite preparation with removing lice, it is characterized in that: be made into shampoo.
4. animal according to claim 1 drives the demodicid mite preparation with removing lice, it is characterized in that: also comprise following material:
Cremophor RH40,2 parts-3 parts;
Tween 20,2 parts-3 parts;
The oil-soluble azone, 0.1 part-0.5 part;
Disodiumedetate, 0.1 part-0.2 part.
5. animal according to claim 4 drives the demodicid mite preparation with removing lice, it is characterized in that: be made into spray or propellant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210511709 CN103006465A (en) | 2012-12-04 | 2012-12-04 | Delousing and acarid expelling preparation for animals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210511709 CN103006465A (en) | 2012-12-04 | 2012-12-04 | Delousing and acarid expelling preparation for animals |
Publications (1)
| Publication Number | Publication Date |
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| CN103006465A true CN103006465A (en) | 2013-04-03 |
Family
ID=47955935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210511709 Pending CN103006465A (en) | 2012-12-04 | 2012-12-04 | Delousing and acarid expelling preparation for animals |
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| CN (1) | CN103006465A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103315921A (en) * | 2013-06-28 | 2013-09-25 | 广州丹奇日用化工厂有限公司 | Shower gel |
| CN106361611A (en) * | 2016-11-07 | 2017-02-01 | 成都绿金生物科技有限责任公司 | Insect and acarus killing shampoo for animals and preparation method thereof |
| CN106491399A (en) * | 2016-11-07 | 2017-03-15 | 成都绿金生物科技有限责任公司 | A kind of removing lice drives demodicid mite spray and preparation method thereof |
| CN106619309A (en) * | 2017-01-09 | 2017-05-10 | 杭州科润生物科技有限公司 | Pet nursing agent and preparation method thereof |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
| CN108030703A (en) * | 2017-12-20 | 2018-05-15 | 广东多尼斯生物科技有限公司 | Nano silver antibacterial itch-stopping bactericidal shampoo for pets and its production method |
| CN108042397A (en) * | 2017-12-20 | 2018-05-18 | 广东多尼斯生物科技有限公司 | Fluffy lasting shampoo for pets and its production method |
| CN108379129A (en) * | 2018-05-15 | 2018-08-10 | 淳安县千岛湖佳蔚日用品有限公司 | A kind of deinsectization shampoo for pets and preparation method thereof |
| CN109221111A (en) * | 2018-09-14 | 2019-01-18 | 柯林森·哈德罗·休 | It is a kind of for treating the drug of poultry louse |
| WO2020047991A1 (en) * | 2018-09-03 | 2020-03-12 | 范俊 | Use of anti-acarid additive in daily chemical products |
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2012
- 2012-12-04 CN CN 201210511709 patent/CN103006465A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103315921B (en) * | 2013-06-28 | 2014-10-22 | 广州丹奇日用化工厂有限公司 | Shower gel |
| CN103315921A (en) * | 2013-06-28 | 2013-09-25 | 广州丹奇日用化工厂有限公司 | Shower gel |
| CN106491399B (en) * | 2016-11-07 | 2019-11-19 | 成都绿金生物科技有限责任公司 | One kind driving mite spray and preparation method thereof except lice |
| CN106361611A (en) * | 2016-11-07 | 2017-02-01 | 成都绿金生物科技有限责任公司 | Insect and acarus killing shampoo for animals and preparation method thereof |
| CN106491399A (en) * | 2016-11-07 | 2017-03-15 | 成都绿金生物科技有限责任公司 | A kind of removing lice drives demodicid mite spray and preparation method thereof |
| CN106619309A (en) * | 2017-01-09 | 2017-05-10 | 杭州科润生物科技有限公司 | Pet nursing agent and preparation method thereof |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
| CN107049868B (en) * | 2017-05-03 | 2020-06-05 | 中国农业科学院兰州畜牧与兽药研究所 | Disinfecting detergent for pets and preparation method thereof |
| CN108030703A (en) * | 2017-12-20 | 2018-05-15 | 广东多尼斯生物科技有限公司 | Nano silver antibacterial itch-stopping bactericidal shampoo for pets and its production method |
| CN108042397A (en) * | 2017-12-20 | 2018-05-18 | 广东多尼斯生物科技有限公司 | Fluffy lasting shampoo for pets and its production method |
| CN108379129A (en) * | 2018-05-15 | 2018-08-10 | 淳安县千岛湖佳蔚日用品有限公司 | A kind of deinsectization shampoo for pets and preparation method thereof |
| WO2020047991A1 (en) * | 2018-09-03 | 2020-03-12 | 范俊 | Use of anti-acarid additive in daily chemical products |
| CN109221111A (en) * | 2018-09-14 | 2019-01-18 | 柯林森·哈德罗·休 | It is a kind of for treating the drug of poultry louse |
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Application publication date: 20130403 |