CN103002909B - 包含含有至少一个cxxc基序的多肽和异源抗原的药物组合物及其用途 - Google Patents
包含含有至少一个cxxc基序的多肽和异源抗原的药物组合物及其用途 Download PDFInfo
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- CN103002909B CN103002909B CN201180017201.7A CN201180017201A CN103002909B CN 103002909 B CN103002909 B CN 103002909B CN 201180017201 A CN201180017201 A CN 201180017201A CN 103002909 B CN103002909 B CN 103002909B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/145—Rhabdoviridae, e.g. rabies virus, Duvenhage virus, Mokola virus or vesicular stomatitis virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K2039/525—Virus
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13023—Virus like particles [VLP]
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
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- Virology (AREA)
- Public Health (AREA)
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- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Engineering & Computer Science (AREA)
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- Pulmonology (AREA)
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- Tropical Medicine & Parasitology (AREA)
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- Biomedical Technology (AREA)
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- AIDS & HIV (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10305317 | 2010-03-29 | ||
| EP10305317.9 | 2010-03-29 | ||
| PCT/EP2011/054866 WO2011120994A1 (en) | 2010-03-29 | 2011-03-29 | Pharmaceutical compositions comprising a polypeptide comprising at least one cxxc motif and heterologous antigens and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103002909A CN103002909A (zh) | 2013-03-27 |
| CN103002909B true CN103002909B (zh) | 2016-06-29 |
Family
ID=42312972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180017201.7A Expired - Fee Related CN103002909B (zh) | 2010-03-29 | 2011-03-29 | 包含含有至少一个cxxc基序的多肽和异源抗原的药物组合物及其用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9801927B2 (enExample) |
| EP (2) | EP3156068B1 (enExample) |
| JP (1) | JP5942296B2 (enExample) |
| KR (1) | KR101866301B1 (enExample) |
| CN (1) | CN103002909B (enExample) |
| AR (1) | AR081809A1 (enExample) |
| BR (1) | BR112012024872B1 (enExample) |
| CA (1) | CA2792174C (enExample) |
| ES (1) | ES2619077T3 (enExample) |
| SG (1) | SG183977A1 (enExample) |
| UY (1) | UY33297A (enExample) |
| WO (1) | WO2011120994A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2476435T (pt) | 2006-08-11 | 2018-03-05 | Life Sciences Res Partners Vzw | Péptidos imunogénicos e a sua utilização em distúrbios imunitários |
| US8999346B2 (en) | 2008-02-14 | 2015-04-07 | Life Sciences Research Partners Vzw | Immunogenic control of tumours and tumour cells |
| WO2009101204A2 (en) * | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Elimination of immune responses to viral vectors |
| US9248171B2 (en) * | 2008-02-14 | 2016-02-02 | Imcyse Sa | Immunogenic peptides and their use in transplantation |
| CA2715611C (en) | 2008-02-14 | 2018-03-13 | Life Sciences Research Partners Vzw | Immunotherapy targeting intracellular pathogens |
| WO2009101206A2 (en) * | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Strategies to prevent and/or treat immune responses to soluble allofactors |
| RU2615460C2 (ru) | 2010-11-25 | 2017-04-04 | Имнейт Сарл | Иммуногенные пептиды для применения в профилактике и/или лечении инфекционных заболеваний, аутоиммунных заболеваний, иммунных ответов на аллогенные факторы, аллергических заболеваний, опухолей, отторжения трансплантата и иммунных ответов против вирусных векторов. используемых для генной терапии или генной вакцинации |
| GB201201511D0 (en) | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
| US9457096B2 (en) | 2012-07-06 | 2016-10-04 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Concet) | Protozoan variant-specific surface proteins (VSP) as carriers for oral drug delivery |
| JP2014212722A (ja) * | 2013-04-24 | 2014-11-17 | 学校法人加計学園 | 八面体構造を有するb型肝炎ウイルス様粒子結晶 |
| GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
| GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
| US10729791B2 (en) * | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
| EP3352782B1 (en) | 2015-09-25 | 2021-03-31 | ImCyse SA | Improved methods and compounds for eliminating immune responses to therapeutic agents |
| KR20240015731A (ko) | 2016-04-19 | 2024-02-05 | 임시스 에스에이 | 신규 면역원성 CD1d 결합 펩티드 |
| JP7102430B2 (ja) | 2017-03-09 | 2022-07-19 | アンシス・エスア | 糖尿病の治療のためのペプチド及び方法 |
| EP4144752A1 (en) * | 2021-09-02 | 2023-03-08 | Sorbonne Universite | Viral-like particles for the treatment or prevention of an infection by a coronaviridae virus |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002034893A2 (en) * | 2000-10-26 | 2002-05-02 | Genopoïetic | Synthetic viruses and uses thereof |
| WO2006093516A2 (en) * | 2004-06-22 | 2006-09-08 | The Regents Of The University Of California | Peptide-coated nanoparticles with graded shell compositions |
| WO2008094197A2 (en) * | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6165469A (en) * | 1988-01-13 | 2000-12-26 | University Of Virginia | Recombinant Entamoeba histolytica lectin subunit peptides and reagents specific for members of the 170 kD subunit multigene family |
| DE60041042D1 (de) * | 1999-03-12 | 2009-01-22 | Aventis Pasteur | Chlamydia antigene und deren korrespondierende dna fragmente und verwendungen davon |
| EP2392345A3 (en) | 2002-07-18 | 2012-03-07 | Cytos Biotechnology AG | Hapten-carrier conjugates comprising virus like particles and uses thereof |
| DE502004010408D1 (de) | 2004-07-02 | 2009-12-31 | Schoelly Fiberoptic Gmbh | Vorrichtung und verwendung der vorrichtung zur aufnahme und verarbeitung eines bildes |
| WO2006026746A2 (en) | 2004-08-31 | 2006-03-09 | The Government Of United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to separate and expand antigen-specific t cells |
| GB0426641D0 (en) * | 2004-12-03 | 2005-01-05 | Bioactive Protein Delivery The | Protein delivery system |
| WO2007122388A2 (en) | 2006-04-13 | 2007-11-01 | Midatech Limited | Nanoparticles containing three various ligands for providing immune responses against infectious agents |
| PT2476435T (pt) * | 2006-08-11 | 2018-03-05 | Life Sciences Res Partners Vzw | Péptidos imunogénicos e a sua utilização em distúrbios imunitários |
| EP2199301A1 (en) * | 2008-12-19 | 2010-06-23 | DKFZ Deutsches Krebsforschungszentrum | Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or fragment thereof |
-
2011
- 2011-03-29 CN CN201180017201.7A patent/CN103002909B/zh not_active Expired - Fee Related
- 2011-03-29 JP JP2013501816A patent/JP5942296B2/ja not_active Expired - Fee Related
- 2011-03-29 EP EP16002285.1A patent/EP3156068B1/en active Active
- 2011-03-29 UY UY0001033297A patent/UY33297A/es active IP Right Grant
- 2011-03-29 KR KR1020127028358A patent/KR101866301B1/ko not_active Expired - Fee Related
- 2011-03-29 CA CA2792174A patent/CA2792174C/en active Active
- 2011-03-29 SG SG2012066791A patent/SG183977A1/en unknown
- 2011-03-29 BR BR112012024872-3A patent/BR112012024872B1/pt active IP Right Grant
- 2011-03-29 ES ES11710794.6T patent/ES2619077T3/es active Active
- 2011-03-29 WO PCT/EP2011/054866 patent/WO2011120994A1/en not_active Ceased
- 2011-03-29 EP EP11710794.6A patent/EP2552476B1/en active Active
- 2011-03-29 US US13/636,482 patent/US9801927B2/en active Active
- 2011-03-29 AR ARP110101036A patent/AR081809A1/es not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002034893A2 (en) * | 2000-10-26 | 2002-05-02 | Genopoïetic | Synthetic viruses and uses thereof |
| WO2006093516A2 (en) * | 2004-06-22 | 2006-09-08 | The Regents Of The University Of California | Peptide-coated nanoparticles with graded shell compositions |
| WO2008094197A2 (en) * | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
Non-Patent Citations (3)
| Title |
|---|
| Conformationally correct expression of membrane-anchored Toxoplasma gondii SAG1 in the primitive protozoan Giardia duodenalis;Matthias Marti et al;《INFECTION AND IMMUNITY》;20021231;第70卷(第2期);全文 * |
| Protective Immunity against Streptococcus mutans Infection in Mice after Intranasal Immunization with the Glucan-Binding Region of S. mutans Glucosyltransferase;CHRISTINA JESPERSGAARD et al;《INFECTION AND IMMUNITY》;19991231;第67卷(第12期);全文 * |
| Systemic and Local Antibody Response in Mice Induced by a Recombinant Peptide Fragment from Giardia Zamblia Variant Surface Protein (VSP) H7 Produced by a Salmonella typhimwium Vaccine Strain;S. STAGER, B. GOTTSTEIN et al;《Intemnarionoi Journal for Parasilology》;19971231;第27卷(第8期);摘要、第968页右栏第2段 * |
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| CA2792174C (en) | 2019-09-24 |
| KR20130063497A (ko) | 2013-06-14 |
| CA2792174A1 (en) | 2011-10-06 |
| UY33297A (es) | 2011-09-30 |
| KR101866301B1 (ko) | 2018-06-11 |
| BR112012024872B1 (pt) | 2022-01-11 |
| JP2013523686A (ja) | 2013-06-17 |
| EP2552476A1 (en) | 2013-02-06 |
| JP5942296B2 (ja) | 2016-06-29 |
| CN103002909A (zh) | 2013-03-27 |
| EP2552476B1 (en) | 2016-12-07 |
| AR081809A1 (es) | 2012-10-24 |
| EP3156068B1 (en) | 2021-11-03 |
| US9801927B2 (en) | 2017-10-31 |
| EP3156068A1 (en) | 2017-04-19 |
| WO2011120994A1 (en) | 2011-10-06 |
| US20130095133A1 (en) | 2013-04-18 |
| BR112012024872A2 (enExample) | 2017-08-15 |
| SG183977A1 (en) | 2012-10-30 |
| ES2619077T3 (es) | 2017-06-23 |
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