CN102998440A - Dry chemical multinomial detecting device - Google Patents
Dry chemical multinomial detecting device Download PDFInfo
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- CN102998440A CN102998440A CN2012105812660A CN201210581266A CN102998440A CN 102998440 A CN102998440 A CN 102998440A CN 2012105812660 A CN2012105812660 A CN 2012105812660A CN 201210581266 A CN201210581266 A CN 201210581266A CN 102998440 A CN102998440 A CN 102998440A
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Abstract
The invention relates to a device for detecting biochemical indexes of human bodies, in particular to a dry chemical multinomial detecting device. The dry chemical multinomial detecting device is fast in detecting speed, high in efficiency, convenient to operate, simple to manufacture, and lower in cost, and can detect multiple projects simultaneously. The dry chemical multinomial detecting device comprises a bottom lining card, wherein an adding sample filtering area, a sample flow pad and a plurality of bumps are arranged on the bottom lining card, the adding sample filtering area contacts with the sample flow pad, a reaction area is arranged on each bump, reaction areas comprise at least a set of reaction film, one end of the reaction film is fixed on the bump, and the other end of the reaction film is located above the sample flow pad.
Description
Technical field
The present invention relates to a kind of device for the detection of human body biochemical indicator, particularly relate to the multinomial pick-up unit of a kind of dry chemical.
Background technology
As everyone knows, the multinomial pick-up unit of dry chemical is a kind of device for the detection of human body biochemical indicator, and is significant for clinical diagnose; At present, the detection of every biochemical indicator is finished according to the relevant former reason Biochemical Analyzer of detection of measured object and corresponding detection kit control usually in the blood, and its application is comparatively extensive.
In recent years, the development of dry chemical detection technique becomes a novel biochemical inspection technology rapidly.The dry chemical detection technique is accepted by clinical labororatory take its unique performance, becomes the new force of clinical biochemical check routine and emergency treatment testing; Compare with classic method, it have simple to operate, speed fast, pollute less, the result stablizes the plurality of advantages such as accurate; The mode that dry chemical detects, each chemistry that normally will participate in reacting, biological reagent be wiring solution-forming in proportion, is added on the solid phase reaction carrier, can be used for after drying clinical detection.In the testing process, the chemical agent dissolves speed of using in the dry chemical detection method is fast, local concentration is high, reaction velocity is fast, simultaneously, can guarantee that some reagent maintain a long-term stability under solid dry material state.
Existing technology and its defective that detects for the human body biochemical indicator is as follows:
The tradition method of inspection: the volume of Biochemical Analyzer own is large, need the professional to configure reagent, and sample needs that pre-service (centrifugal etc.), pattern detection time are long, the operation relative complex.
Dry chemical scrip: testing cost wants high detection efficient lower than classic method, and test strips (or bleed) once can only detect single single project.
Dry chemical detecting plate: although function is comparatively comprehensive, it is high that the relative dry chemical scrip of detection efficiency is wanted, and it exists manufacture craft too complicated, high cost.
Summary of the invention
For solving the problems of the technologies described above, the invention provides that a kind of detection speed is fast, efficient is high, easy and simple to handle, can detect simultaneously a plurality of projects simultaneously, and make simple, the multinomial pick-up unit of dry chemical that relative cost reduces.
The multinomial pick-up unit of dry chemical of the present invention, comprise the end liner card, be provided with application of sample filtrating area, sample flow pad and a plurality of projection on the described end liner card, described application of sample filtrating area contacts with the sample flow pad, be provided with reaction zone on each projection in described a plurality of projection, described reaction zone comprises at least one group reaction film, and an end of reaction film is fixed on the projection, and the other end of described reaction film is positioned at the top of described sample flow pad.
The multinomial pick-up unit of dry chemical of the present invention, described application of sample filtrating area comprises diffusion layer, sample pad and hemofiltration film, and described diffusion layer is positioned at the top of sample pad, and described sample pad is positioned at the top of hemofiltration film; Described diffusion layer, sample pad and hemofiltration film are bonded together by bonding piece, and described diffusion layer, sample pad and hemofiltration film be bonded on the end liner card by bonding piece, and described sample flow pad is positioned at the below of described hemofiltration film.
The multinomial pick-up unit of dry chemical of the present invention also comprises cover plate, and described cover plate is fixedly mounted on the top of described end liner card, and is provided with the hole of arranging in pairs or groups mutually with application of sample filtrating area and reaction zone at described cover plate.
The multinomial pick-up unit of dry chemical of the present invention, described cover plate fastens together by buckle and end liner.
The multinomial pick-up unit of dry chemical of the present invention, described end liner card and cover plate are made by the high rigidity hydrophobic polymeric material.
The multinomial pick-up unit of dry chemical of the present invention, described end liner card and cover plate are made by tygon or Polyvinylchloride or polypropylene or polycarbonate or organic glass.
The multinomial pick-up unit of dry chemical of the present invention, described sample flow pad is sticking to be contained on the described end liner card.
Compared with prior art beneficial effect of the present invention is: be provided with the end liner card, be provided with application of sample filtrating area, sample flow pad and a plurality of projection on the end liner card, the application of sample filtrating area contacts with the sample flow pad, be provided with reaction zone on each projection in a plurality of projections, reaction zone comprises at least one group reaction film, and an end of reaction film is fixed on the projection, and the other end of reaction film is positioned at the top of sample flow pad.Like this, can carry out by the application of sample filtrating area filtration of blood sample, whole blood at the application of sample filtrating area after filtering, in the serum (or blood plasma) measured object with serum (or blood plasma) below the sample flow pad is passed to each reaction zone, control through the particular detection instrument, press down the reaction film of reaction zone, reaction film contacts with serum (or blood plasma) on the sample flow pad, measured object in the serum (or blood plasma) with chromogenic reaction can occur after the chemical reagent on the reaction film contacts, the reaction film variable color, again by the optical detection elements (light source on the particular detection instrument, sensor), change color on the detection reaction film, and then calculate the concentration of measured object; This process detection speed is fast, efficient is high, easy and simple to handle, can detect simultaneously a plurality of projects simultaneously, and make simply, relative cost reduces.
Description of drawings
Fig. 1 is the structural representation that the multinomial pick-up unit of dry chemical of the present invention does not contain cover plate;
Fig. 2 is that the plan structure schematic diagram is looked on the left side of Fig. 1;
Fig. 3 is the structural representation of the multinomial pick-up unit cover plate of dry chemical of the present invention.
Embodiment
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following examples are used for explanation the present invention, but are not used for limiting the scope of the invention.
As shown in Figure 1, the multinomial pick-up unit of dry chemical of the present invention, comprise end liner card 1, be provided with application of sample filtrating area 2, sample flow pad 3 and a plurality of projection 4 on the end liner card, application of sample filtrating area contact with the sample flow pad (way of contact herein is the application of sample filtrating area, and stack contacts with the sample flow pad), be provided with reaction zone 5 in a plurality of projections on each projection, reaction zone comprises at least one group reaction film, and an end of reaction film is fixed on the projection, and the other end of reaction film is positioned at the top of sample flow pad; Like this, can carry out by the application of sample filtrating area filtration of blood sample, whole blood at the application of sample filtrating area after filtering, in the serum (or blood plasma) measured object with serum (or blood plasma) below the sample flow pad is passed to each reaction zone, control through the particular detection instrument, press down the reaction film of reaction zone, reaction film contacts with serum (or blood plasma) on the sample flow pad, measured object in the serum (or blood plasma) with chromogenic reaction can occur after the chemical reagent on the reaction film contacts, the reaction film variable color, again by the optical detection elements (light source on the particular detection instrument, sensor), change color on the detection reaction film, and then calculate the concentration of measured object; This process detection speed is fast, efficient is high, easy and simple to handle, can detect simultaneously a plurality of projects simultaneously, and make simply, relative cost reduces.
As shown in Figure 2, the multinomial pick-up unit of dry chemical of the present invention, application of sample filtrating area comprise diffusion layer 21, sample pad 22 and hemofiltration film 23, and diffusion layer is positioned at the top of sample pad, and sample pad is positioned at the top of hemofiltration film; Diffusion layer, sample pad and hemofiltration film are bonded together by bonding piece 24, and diffusion layer, sample pad and hemofiltration film are bonded on the end liner card by bonding piece, the sample flow pad is positioned at the below of hemofiltration film, the application of sample filtrating area is in order to carry out filtration treatment to whole blood sample herein, separate and obtain serum (or blood plasma), can select as required commercially available sample loading material, the Whole Blood Filtration material, such as glass fiber material of different pore size etc., diffusion layer in the application of sample filtrating area, sample pad and hemofiltration film can according to detecting needs, solidify or coated chemical reagent or the auxiliary reagent relevant with test reaction; Like this, can reach the purpose of optimizing reaction system or promotion serum sample flowability.
As shown in Figure 3, the multinomial pick-up unit of dry chemical of the present invention also comprises cover plate 6, and cover plate is fixedly mounted on the top of end liner card, and on the cover board is provided with the hole of arranging in pairs or groups mutually with application of sample filtrating area and reaction zone; Cover plate prevents from coming off in order to fastening application of sample filtrating area, sample flow pad, reaction zone, all designs the hole so that application of sample operation and instrument detect at application of sample filtrating area and each reaction zone center.
The multinomial pick-up unit of dry chemical of the present invention, cover plate fastens together by buckle and end liner, and like this, the chucking of being more convenient for is fixing.
The multinomial pick-up unit of dry chemical of the present invention, end liner card and cover plate are made by the high rigidity hydrophobic polymeric material.
The multinomial pick-up unit of dry chemical of the present invention, end liner card and cover plate are made by tygon or Polyvinylchloride or polypropylene or polycarbonate or organic glass, in an embodiment of the present invention, mainly adopt makrolon material to make.
The multinomial pick-up unit of dry chemical of the present invention, the sample flow pad is sticking to be contained on the end liner card.
The multinomial pick-up unit of dry chemical of the present invention, reaction zone comprises many group reactions film, and the stack of many group reactions film is fixed together.
The multinomial pick-up unit of dry chemical of the present invention, in the design of reaction zone and reaction film, the quantity of reaction film is carried out design alternative according to the test item needs, and reaction zone is set all on each projection, like this, each reaction zone that forms in a plurality of reaction zones detects a physiochemical indice, therefore the multinomial pick-up unit of dry chemical can be bled to one simultaneously and be carried out the many index detection, the reaction film of mentioning among the present invention is a kind of macromolecule member material, in order to the required main chemical reagent of fixing bearing test reaction.Its material can but be not limited to commercially available nitrocellulose filter, polysulfone membrane, polyester film, polycarbonate membrane, all-glass paper etc.
The multinomial pick-up unit of dry chemical of the present invention, diffusion layer, sample pad and hemofiltration film have used respectively the glass fiber material of different pore size and thickness, the auxiliary reagents such as surfactant wherein have been coated with in advance on the sample pad, the sample flow pad is a kind of very thin glass fiber material in the present embodiment, be cut into tee T, the stack of one end and sample application zone contact, the serum (or blood plasma) that the absorption whole blood sample obtains after filtering, first after vertical transmission again lateral transport to each reaction zone.
The above only is preferred implementation of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the technology of the present invention principle; can also make some improvement and modification, these improve and modification also should be considered as protection scope of the present invention.
Claims (8)
1. multinomial pick-up unit of dry chemical, it is characterized in that, comprise the end liner card, be provided with application of sample filtrating area, sample flow pad and a plurality of projection on the described end liner card, described application of sample filtrating area contacts with the sample flow pad, is provided with reaction zone on each projection in described a plurality of projections, and described reaction zone comprises at least one group reaction film, and an end of reaction film is fixed on the projection, and the other end of described reaction film is positioned at the top of described sample flow pad.
2. the multinomial pick-up unit of dry chemical as claimed in claim 1 is characterized in that, described application of sample filtrating area comprises diffusion layer, sample pad and hemofiltration film, and described diffusion layer is positioned at the top of sample pad, and described sample pad is positioned at the top of hemofiltration film; Described diffusion layer, sample pad and hemofiltration film are bonded together by bonding piece, and described diffusion layer, sample pad and hemofiltration film be bonded on the end liner card by bonding piece, and described sample flow pad is positioned at the below of described hemofiltration film.
3. the multinomial pick-up unit of dry chemical as claimed in claim 1 is characterized in that, also comprises cover plate, and described cover plate is fixedly mounted on the top of described end liner card, and is provided with the hole of arranging in pairs or groups mutually with application of sample filtrating area and reaction zone at described cover plate.
4. the multinomial pick-up unit of dry chemical as claimed in claim 3 is characterized in that, described cover plate fastens together by buckle and end liner.
5. such as claim 3 or the multinomial pick-up unit of 4 described dry chemical, it is characterized in that, described end liner card and cover plate are made by the high rigidity hydrophobic polymeric material.
6. the multinomial pick-up unit of dry chemical as claimed in claim 5 is characterized in that, described end liner card and cover plate are made by tygon or Polyvinylchloride or polypropylene or polycarbonate or organic glass.
7. the multinomial pick-up unit of dry chemical as claimed in claim 1 is characterized in that, described sample flow pad is sticking to be contained on the described end liner card.
8. the multinomial pick-up unit of dry chemical as claimed in claim 1 is characterized in that, described reaction zone comprises many group reactions film, and the stack of many group reactions film is fixed together.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105812660A CN102998440A (en) | 2012-12-28 | 2012-12-28 | Dry chemical multinomial detecting device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105812660A CN102998440A (en) | 2012-12-28 | 2012-12-28 | Dry chemical multinomial detecting device |
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| CN102998440A true CN102998440A (en) | 2013-03-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012105812660A Pending CN102998440A (en) | 2012-12-28 | 2012-12-28 | Dry chemical multinomial detecting device |
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| CN (1) | CN102998440A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105223349A (en) * | 2014-07-01 | 2016-01-06 | 艾博生物医药(杭州)有限公司 | A kind of device detecting sample |
| CN109490535A (en) * | 2018-10-22 | 2019-03-19 | 湖北洁源检测有限公司 | A kind of multi-channel synchronous immunochromatography detection system and detection method |
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| CN102288746A (en) * | 2011-07-12 | 2011-12-21 | 英科新创(厦门)科技有限公司 | Blood screening joint detection card |
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| CN102321730A (en) * | 2011-06-23 | 2012-01-18 | 泰普生物科学（中国）有限公司 | Joint vaginitis detection kit |
| CN102323399A (en) * | 2011-09-16 | 2012-01-18 | 苏州生物医学工程技术研究所 | Multilayer film dry chemical reagent tablet for detecting alanine aminotransferase |
| CN202126405U (en) * | 2011-04-11 | 2012-01-25 | 深圳市博卡生物技术有限公司 | Dry chemical detecting plate |
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Patent Citations (10)
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| US20070031972A1 (en) * | 2005-08-05 | 2007-02-08 | Attar Amir J | Detection of poisons in materials such as food using colorimetric detection |
| CN101261270A (en) * | 2007-03-09 | 2008-09-10 | 中国人民解放军军事医学科学院微生物流行病研究所 | Immunity-chromatography multiple detection test paper disk and immunity-chromatography multiple detection method |
| CN201392340Y (en) * | 2009-04-21 | 2010-01-27 | 山东博科生物产业有限公司 | Multi-item test reagent card |
| CN201903547U (en) * | 2010-11-29 | 2011-07-20 | 深圳市博卡生物技术有限公司 | Rapid detection test strip |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105223349A (en) * | 2014-07-01 | 2016-01-06 | 艾博生物医药(杭州)有限公司 | A kind of device detecting sample |
| CN109490535A (en) * | 2018-10-22 | 2019-03-19 | 湖北洁源检测有限公司 | A kind of multi-channel synchronous immunochromatography detection system and detection method |
| CN109490535B (en) * | 2018-10-22 | 2022-03-25 | 湖北洁源检测有限公司 | Multichannel synchronous immunochromatography detection system and detection method |
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Application publication date: 20130327 |