CN102988683A - Kidney and spleen tonifying pill for preventing and treating osteoporosis - Google Patents
Kidney and spleen tonifying pill for preventing and treating osteoporosis Download PDFInfo
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- CN102988683A CN102988683A CN2012103911816A CN201210391181A CN102988683A CN 102988683 A CN102988683 A CN 102988683A CN 2012103911816 A CN2012103911816 A CN 2012103911816A CN 201210391181 A CN201210391181 A CN 201210391181A CN 102988683 A CN102988683 A CN 102988683A
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Abstract
The invention provides a kidney and spleen tonifying pill for preventing and treating osteoporosis. The pill is prepared by uniformly mixing, crushing and pelleting the following components in parts by weight: 8 to 15 parts of astragalus, 8 to 12 parts codonopsis pilosula, 8 to 12 parts of fried bighead atractylodes rhizome, 8 to 12 parts of fried yam, and 30 to 60 parts of chondroitin sulfate. The product has good effect of preventing and treating osteoporosis.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to the osteoporotic Yishen Jianpi ball of a kind of control.
Background technology
Osteoporosis (osteoporosis) is a kind of systemic osteopathia, it is characterized in that the bone amount descends and the fine structure of bone destroys, the fragility that shows as bone increases, thereby the danger of fracture greatly increases, even also easily fracture in slight wound or the atraumatic situation.Osteoporosis is a kind of chronic disease due to multifactor.Before fracture occurs, usually without Special Clinical Manifestation.The women is more than the male for this disease, is common in postmenopausal women and old people.Along with the increase of China's aging population, the osteoporosis sickness rate is in ascendant trend, all is a health problem that merits attention in China and even the whole world.
Motherland's medical science think primary disease generation, the development and " kidney qi " closely related, " the contrary opinion of transferring of Plain Questions " said: " kidney is not given birth to; then marrow can not be expired ", " Plain Questions six joints are hidden and resembled opinion " said: " kidney person, the master stings the dominator of storing essence; smart part is also; its Hua Zaifa, and it fills at bone " ", therefore its employing invigorating the kidney and strengthening the bones, invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral are all obtained preferably effect.
The traditional Chinese medical science adopts differentiation of symptoms and signs for classification of syndrome, for different types, adopts the prescription of suiting the medicine to the illness.As adopting the prescription of nourishing the liver and kidney, bone and muscle strengthening for deficiency of the liver and kidney, such as square medicine: chien pu hu chien wan: 2 parts of Colla Plastri Testudinis, 2 parts of Colla cornus cervis, 2 parts of Tigris shins (now use Os Canitis generation), 2 parts of Radix Polygoni Multiflori, 2 parts of Radix Cyathulaes, 2 parts of the Cortexs Eucommiae, 2 parts of Herba Cynomoriis, 2 parts of Radix Angelicae Sinensis, 2 parts of Radix Rehmanniae Preparata, 2 parts of Radix Clematidis, 1 part of Cortex Phellodendri, 1 part of Radix Ginseng, 1 part of Rhizoma Et Radix Notopterygii, 1 part of the Radix Paeoniae Alba, 1 part of the Rhizoma Atractylodis Macrocephalae, 1.5 parts of great river Radix Aconiti Lateralis Preparatas, Mel is an amount of.Grind and be smalls, refined honey ball such as Semen phaseoli radiati are large).Every 10 grams that take, light salt brine send down every day 2~3 times on an empty stomach.
Adopt the prescription of Yishen Jianpi for yang deficiency of spleen and stomache, such as square medicine: SHENLING BAISHU SAN is closed Yougui Yin, the kidney-Yang-Reinkforcing Decotion: Semen Nelumbinis (peeling) 500 grams, and Semen Coicis 50 restrains, contracting Fructus Amomi 50 grams, Radix Platycodonis (stir-fry makes buff) 50 grams, (Sucus Zingberis soaks Semen Lablab Album, peeling, little stir-fry) 75 grams, Poria 100 grams, Radix Ginseng 100 grams, Radix Glycyrrhizae (stir-fry) 100 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Rhizoma Dioscoreae 100 grams.Grind and be smalls, each serving 6 grams, Fructus Jujubae is fried in shallow oil soup and is taken.
Adopt the prescription of blood-activating and qi-promoting, removing obstruction in the collateral to relieve pain for qi stagnation and blood stasis type, such as square medicine: Traditional Chinese medicine decoction for treating-ache and expelling atagnate: Radix Gentianae Macrophyllae 3 grams, Rhizoma Chuanxiong 6 grams, Semen Persicae 9 grams, Flos Carthami 9 grams, Radix Glycyrrhizae 6 grams, Rhizoma Et Radix Notopterygii 3 grams, Myrrha 6 grams, Radix Angelicae Sinensis 9 grams, Oletum Trogopterori (stir-fry) 6 grams, Rhizoma Cyperi 3 grams, Radix Achyranthis Bidentatae 9 grams, Pheretima 6 grams.Be decocted in water for oral dose, avoid cold and uncooked food greasy, be not taken by pregnant women.
Chondroitin sulfate (Chondroitin sulfate) is present in the animal cartilage in a large number, is the acid mucopolysaccharide that extracts preparation from animal tissue.Chondroitin sulfate is a kind of of glycosaminoglycans, by D-glucuronic acid and N-acetylamino galactosamine with β-1, the polysaccharide that the repetition disaccharide unit that the 4-glycosidic bond is formed by connecting forms, and at C-4 position or the C-6 position hydroxyl of N-acetylamino galactosamine Sulfation occurs, be mainly used in arthritis, eye drop etc., studies show that, chondroitin sulfate can promote osteoblast hypertrophy and new bone formation." the sulfated compound chrondroitin is to the therapeutical effect of rats with osteoporosis for scientific and technical literature
" (Liu Xiuju, Zhang Jixian, Mu Zhongxiang etc., " food and pharmaceutical " 05 phase in 2008) study the effect that the sulfated compound chrondroitin is treated the rats with osteoporosis of Induced by Retinoic Acid, the result shows, compare with model group, high, the middle dosage group of sulfated compound chrondroitin can significantly increase rat body weight, improves bone mineral content and bone density, reduces serum alkaline phosphatase (ALP) level, and can significantly improve the biomechanical parameter of femur, rats with osteoporosis there is therapeutical effect.
There is no at present the drug regimen of Chinese medicine and chondroitin sulfate is studied.
Summary of the invention
The invention provides the osteoporotic Yishen Jianpi ball of a kind of control, adopt Chinese medicine and the chondroitin sulfate combined treatment osteoporosis of Yishen Jianpi for yang deficiency of spleen and stomache.
The concrete technical scheme of the present invention is as follows:
The osteoporotic Yishen Jianpi ball of a kind of control, by Radix Astragali 8-15 part of weight portion, Radix Codonopsis 8-12 part, Rhizoma Atractylodis Macrocephalae (parched) 8-12 part, Rhizoma dioscoreae (parched) 8-12 part and chondroitin sulfate 30-60 part mix homogeneously, through pulverizing, pill and get final product.
Above-mentioned Yishen Jianpi ball, preferably by 15 parts of the Radixs Astragali of weight portion, 12 parts of Radix Codonopsis, 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 12 parts of Rhizoma dioscoreae (parched)s and 60 parts of mix homogeneously of chondroitin sulfate, through pulverizing, pill and get final product.
The specific embodiment
Below in conjunction with instantiation technical scheme of the present invention is described further, helps to understand the present invention, but do not limit content of the present invention.
Embodiment 1
Take by weighing Radix Astragali 8g, Radix Codonopsis 8g, Rhizoma Atractylodis Macrocephalae (parched) 8g, Rhizoma dioscoreae (parched) 8g is dry, adds chondroitin sulfate 30g, pulverizes the 80-100 mesh sieve, mix homogeneously.Molding, transfer mulse an amount of, general ball press the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, and total number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, that the general system of medicated powder is complete.With the pill that makes through steam drying, the granulate packing, by the about 6g packing of 50 of every pouches, per 10 bags is 1 box, sealing and get final product.
Embodiment 2
Take by weighing Radix Astragali 12g, Radix Codonopsis 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Rhizoma dioscoreae (parched) 10g, drying adds chondroitin sulfate 45g, pulverizes the 80-100 mesh sieve, mix homogeneously.Molding, transfer mulse an amount of, general ball press the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, and total number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, that the general system of medicated powder is complete.With the pill that makes through steam drying, the granulate packing, by the about 6g packing of 50 of every pouches, per 10 bags is 1 box, sealing and get final product.
Embodiment 3
Take by weighing Radix Astragali 15g, Radix Codonopsis 12g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Rhizoma dioscoreae (parched) 12g, drying adds chondroitin sulfate 60g, pulverizes the 80-100 mesh sieve, mix homogeneously.Molding, transfer mulse an amount of, general ball press the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, and total number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, that the general system of medicated powder is complete.With the pill that makes through steam drying, the granulate packing, by the about 6g packing of 50 of every pouches, per 10 bags is 1 box, sealing and get final product.
Claims (2)
1. the osteoporotic Yishen Jianpi ball of control is characterized in that the Radix Astragali 8-15 part by weight portion, Radix Codonopsis 8-12 part, and Rhizoma Atractylodis Macrocephalae (parched) 8-12 part, Rhizoma dioscoreae (parched) 8-12 part and chondroitin sulfate 30-60 part mix homogeneously are through pulverizing, pill and get final product.
2. Yishen Jianpi ball as claimed in claim 1 is characterized in that by 15 parts of the Radixs Astragali of weight portion, 12 parts of Radix Codonopsis, and 12 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 12 parts of Rhizoma dioscoreae (parched)s and 60 parts of mix homogeneously of chondroitin sulfate, through pulverizing, pill and get final product.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1466976A (en) * | 2002-07-11 | 2004-01-14 | 武汉健民药业集团股份有限公司 | Medicine for preventing and curing rachitis and osteoporosis and method for preparing the same |
CN101156928A (en) * | 2006-03-12 | 2008-04-09 | 李佳旺 | A Subhealth treating Chinese medicine composition and method of making the same |
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2012
- 2012-10-16 CN CN2012103911816A patent/CN102988683A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1466976A (en) * | 2002-07-11 | 2004-01-14 | 武汉健民药业集团股份有限公司 | Medicine for preventing and curing rachitis and osteoporosis and method for preparing the same |
CN101156928A (en) * | 2006-03-12 | 2008-04-09 | 李佳旺 | A Subhealth treating Chinese medicine composition and method of making the same |
Non-Patent Citations (4)
Title |
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刘秀菊等: "复方硫酸软骨素对大鼠骨质疏松症的治疗作用", 《食品与药品》, vol. 10, no. 05, 10 May 2008 (2008-05-10) * |
曹译等: "鹿茸硫酸软骨素蛋白聚糖的分离纯化研究", 《生物学杂志》, vol. 23, no. 05, 25 October 2006 (2006-10-25), pages 30 - 2 * |
杨红云等: "骨质疏松症中医辨证分型与治疗", 《现代中西医结合杂志》, vol. 21, no. 19, 31 July 2012 (2012-07-31) * |
王军等: "补肾为主治疗骨质疏松症", 《云南中医学院学报》, vol. 22, no. 02, 20 June 1999 (1999-06-20) * |
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Application publication date: 20130327 |