CN103028076B - Traditional Chinese medicine composition for treating liver cirrhosis - Google Patents
Traditional Chinese medicine composition for treating liver cirrhosis Download PDFInfo
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- CN103028076B CN103028076B CN201210562015.8A CN201210562015A CN103028076B CN 103028076 B CN103028076 B CN 103028076B CN 201210562015 A CN201210562015 A CN 201210562015A CN 103028076 B CN103028076 B CN 103028076B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating liver cirrhosis. The traditional Chinese medicine composition for treating the liver cirrhosis comprises the following Chinese herbal raw materials in part by weight: 10-40 parts of codonopsis pilosula, 10-30 parts of poria cocos, 10-30 parts of fried rhizoma atractylodis, 5-20 parts of fructus amomi, 5-25 parts of rhizoma atractylodis, 5-20 parts of apricot kernel, 5-25 parts of agastache rugosus, 10-30 parts of root of red-rooted salvia, 10-40 parts of white paeony root, 10-50 parts of astragalus, 10-30 parts of hawthorn, 5-20 parts of red tangerine peel, 5-25 parts of officinal magnolia bark, 5-20 parts of medlar, 5-20 parts of turtle shell and 5-20 parts of licorice. The traditional Chinese medicine composition has effects of soothing liver and Qi, promoting blood circulation, removing blood stasis, nourishing Yin, soothing liver, softening and removing hard lumps, promoting diuresis and eliminating swelling, and is significant and reliable in therapeutic effect on the liver cirrhosis, wide in medicinal component source, simple and convenient in preparation, mild in medicinal nature and free of toxic side effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of liver cirrhosis.
Background technology
Liver cirrhosis (hepatic cirrhosis) is clinical common chronic progressive external hepatopathy, or diffusivity hepatic injury that repeated action form long-term by one or more causes of disease.In China, great majority are posthepatitic cirrhosis, and small part is alcoholic cirrhosis and Cirrhosis In Schistosomiasis.In histopathology, there are widely hepatic necrosis, remaining hepatocyte nodular regeneration, connective tissue proliferation and fiber every formation, cause lobules of liver structural deterioration and pseudolobuli to form, liver distortion gradually, hardening and develop into liver cirrhosis.Western medical treatment generally adopts antibiotic etc to carry out cycle therapy single or associating, although this artificial cycle therapy takes effect obviously, but also can only solve temporary transient problem, and antibiotic is to liver, gallbladder, cardiovascular, cerebrovascular, and clotting mechanism all there is certain side effect.
The traditional Chinese medical science thinks, liver cirrhosis often shows as the syndromes such as the resistance of blood stasis network, the insufficiency of the spleen stagnation of QI, the hepatic and renal YIN deficiency in clinical.In treatment, be main mainly with depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, yin nourishing easing the affected liver, hard masses softening and resolving, inducing diuresis to remove edema.
According to theory of Chinese medical science, for the pathogeny of liver cirrhosis, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Carry out the deficiency that cycle therapy liver cirrhosis is cured the symptoms, not the disease and side effect is large single or associating in order to overcome in prior art by antibiotic etc, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment liver cirrhosis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of liver cirrhosis, is characterized in that: its raw material of Chinese medicine by following weight portion forms: Radix Codonopsis 10-40 part, Poria 10-30 part, Rhizoma Atractylodis Macrocephalae (parched) 10-30 part, Fructus Amomi 5-20 part, Rhizoma Atractylodis 5-25 part, Semen Armeniacae Amarum 5-20 part, Herba Pogostemonis 5-25 part, Radix Salviae Miltiorrhizae 10-30 part, Radix Paeoniae Alba 10-40 part, Radix Astragali 10-50 part, Fructus Crataegi 10-30 part, Exocarpium Citri Rubrum 5-20 part, Cortex Magnoliae Officinalis 5-25 part, Fructus Lycii 5-20 part, Carapax Trionycis 5-20 part, Radix Glycyrrhizae 5-20 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of liver cirrhosis, is characterized in that: its raw material of Chinese medicine by following weight portion forms: 30 parts of Radix Codonopsis, 20 parts, Poria, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of Fructus Amomis, 15 parts of Rhizoma Atractylodis, 10 parts, Semen Armeniacae Amarum, 15 parts of Herba Pogostemoniss, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of the Radix Paeoniae Albas, 40 parts of the Radixs Astragali, 20 parts of Fructus Crataegis, 10 parts of Exocarpium Citri Rubrums, 15 parts of Cortex Magnoliae Officinalis, 10 parts of Fructus Lyciis, 10 parts of Carapax Trionycis, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Codonopsis has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Rhizoma Atractylodis Macrocephalae (parched) has effect of dampness row water, QI invigorating, strengthening the spleen and stomach; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; Rhizoma Atractylodis have drying damp and strengthening spleen effect; Effect that Semen Armeniacae Amarum has expelling phlegm for arresting cough, numbness is opened in the intestine moistening of relievining asthma, the therapeutic method to keep the adverse QI flowing downwards; Herba Pogostemonis has eliminating turbid pathogen with aromatics, the preventing or arresting vomiting that whets the appetite, deliver effect of expelling summer-heat; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Fructus Crataegi has effect of promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, phlegm reduction of blood circulation promoting; Exocarpium Citri Rubrum has effect of expectorant, promoting the circulation of QI, alleviating distention in middle-JIAO, eliminating stagnation; Cortex Magnoliae Officinalis has dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards except full effect; Fructus Lycii has effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Carapax Trionycis has nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except the effect of steaming; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, complements each other using, and has synergism, and effect of long memorial liver and qi, blood circulation promoting and blood stasis dispelling, yin nourishing easing the affected liver, hard masses softening and resolving, inducing diuresis to remove edema, reaches treating both the principal and secondary aspects of a disease to the treatment of liver cirrhosis altogether.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 90%, cure rate 61.7%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for liver cirrhosis, its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 30g, Poria 20g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Fructus Amomi 10g, Rhizoma Atractylodis 15g, Semen Armeniacae Amarum 10g, Herba Pogostemonis 15g, Radix Salviae Miltiorrhizae 20g, Radix Paeoniae Alba 30g, Radix Astragali 40g, Fructus Crataegi 20g, Exocarpium Citri Rubrum 10g, Cortex Magnoliae Officinalis 15g, Fructus Lycii 10g, Carapax Trionycis 10g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for liver cirrhosis, its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 20g, Poria 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Fructus Amomi 12g, Rhizoma Atractylodis 10g, Semen Armeniacae Amarum 5g, Herba Pogostemonis 20 g, Radix Salviae Miltiorrhizae 30g, Radix Paeoniae Alba 20g, Radix Astragali 30g, Fructus Crataegi 10g, Exocarpium Citri Rubrum 15g, Cortex Magnoliae Officinalis 5g, Fructus Lycii 20g, Carapax Trionycis 12g, Radix Glycyrrhizae 15g.
Embodiment 3
Treat a Chinese medicine composition for liver cirrhosis, its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 10g, Poria 25g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Fructus Amomi 20g, Rhizoma Atractylodis 12g, Semen Armeniacae Amarum 20g, Herba Pogostemonis 10g, Radix Salviae Miltiorrhizae 10g, Radix Paeoniae Alba 25g, Radix Astragali 20g, Fructus Crataegi 15g, Exocarpium Citri Rubrum 20g, Cortex Magnoliae Officinalis 10g, Fructus Lycii 5g, Carapax Trionycis 15g, Radix Glycyrrhizae 20g.
Embodiment 4
Treat a Chinese medicine composition for liver cirrhosis, its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 40g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 30g, Fructus Amomi 5g, Rhizoma Atractylodis 25g, Semen Armeniacae Amarum 15g, Herba Pogostemonis 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 40g, Radix Astragali 10g, Fructus Crataegi 30g, Exocarpium Citri Rubrum 5g, Cortex Magnoliae Officinalis 25g, Fructus Lycii 12g, Carapax Trionycis 20g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a Chinese medicine composition for liver cirrhosis, its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 25g, Poria 15g, Rhizoma Atractylodis Macrocephalae (parched) 25g, Fructus Amomi 15g, Rhizoma Atractylodis 5g, Semen Armeniacae Amarum 12g, Herba Pogostemonis 5g, Radix Salviae Miltiorrhizae 25g, Radix Paeoniae Alba 10g, Radix Astragali 50g, Fructus Crataegi 25g, Exocarpium Citri Rubrum 12g, Cortex Magnoliae Officinalis 20g, Fructus Lycii 15g, Carapax Trionycis 5g, Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 5 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Second decocts, and adds water and does not have approximately 4 centimetres of powder, after water boils, decocts 15～20 minutes.Decoct extracting juice twice, merge.
Treat a Chinese medicine composition for liver cirrhosis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 60 examples, 35～65 years old age.
Two, usage and dosage: when clinical practice, the amounts of components in compositions is taken the circumstances into consideration increase and decrease according to patient's body weight and age.Potion on the one, the about 300ml of twice extracting juice of decocting, point morning, evening take for twice.It within seven days, is a course for the treatment of.
Three, criterion of therapeutical effect:
(1) recovery from illness: sings and symptoms disappears or substantially disappears;
(2) effective: sings and symptoms is most of to take a turn for the better;
(3) effective: a sings and symptoms part takes a turn for the better;
(4) invalid; Sings and symptoms is all not improved, and symptom is as front.
Four, therapeutic effect: in this clinical observation case, take medicine 3-10 the course for the treatment of, recovery from illness 37 examples, effective 10 examples, effective 7 examples, invalid 6 examples.During treatment, there is not toxic and side effects.
Five, model case:
Case 1:
In certain, man, 56 years old.Disease is seen: emaciated physique, and lethargy, pain under rib, oliguria with reddish urine, constipation with dry stool, dysphoria with smothery sensation, bitter taste, thirst but no desire to drink, complexion is dark and not damp, and liver palm is obvious, and abdominal part swells and exceeds chest, hard by it.Examine as liver cirrhosis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom disappears substantially, and women's head-ornaments extremity are all without edema, and food is received normal, and face is glossy, and spirit takes a turn for the better, and continues to take 3 courses for the treatment of, and symptom disappears completely.
Case 2:
Zhang, man, 63 years old.Liver cirrhosis is for 3 years.When medical: health lassitude and weak, the complexion of being afraid of cold is gloomy, and all day is listless, anorexia.Take 3 courses for the treatment of of pharmaceutical treatment prepared by Chinese medicine composition of the present invention, symptom is eased, and continues to take 4 courses for the treatment of, and symptom disappears completely, cures.Follow up a case by regular visits to so far without recurrence.
Claims (1)
1. a Chinese medicine composition for the treatment of liver cirrhosis, is characterized in that: its raw material of Chinese medicine by following weight proportion forms: Radix Codonopsis 30g, Poria 20g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Fructus Amomi 10g, Rhizoma Atractylodis 15g, Semen Armeniacae Amarum 10g, Herba Pogostemonis 15g, Radix Salviae Miltiorrhizae 20g, Radix Paeoniae Alba 30g, Radix Astragali 40g, Fructus Crataegi 20g, Exocarpium Citri Rubrum 10g, Cortex Magnoliae Officinalis 15g, Fructus Lycii 10g, Carapax Trionycis 10g, Radix Glycyrrhizae 10g.
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| CN201210562015.8A CN103028076B (en) | 2012-12-23 | 2012-12-23 | Traditional Chinese medicine composition for treating liver cirrhosis |
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| CN201210562015.8A CN103028076B (en) | 2012-12-23 | 2012-12-23 | Traditional Chinese medicine composition for treating liver cirrhosis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101759436B1 (en) * | 2015-05-22 | 2017-07-19 | 성균관대학교산학협력단 | Composition comprising Pogostemonis Herba extract for preventing or treating liver damage |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103828882A (en) * | 2014-02-11 | 2014-06-04 | 陆开云 | Water chestnut spleen tonifying sesame cake and preparation method thereof |
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| CN101406656A (en) * | 2008-10-23 | 2009-04-15 | 李艳 | Medicament for treating hepatic cirrhosis with hypoproteinemia after hepatitis |
| CN101884764A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating chronic hepatitis splenomegaly or cirrhosis splenomegaly |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406656A (en) * | 2008-10-23 | 2009-04-15 | 李艳 | Medicament for treating hepatic cirrhosis with hypoproteinemia after hepatitis |
| CN101884764A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating chronic hepatitis splenomegaly or cirrhosis splenomegaly |
Non-Patent Citations (2)
| Title |
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| 中药治疗肝硬化腹水体会;郭海涛;《云南中医中药杂志》;20091231;第30卷(第11期);第77-78页 * |
| 郭海涛.中药治疗肝硬化腹水体会.《云南中医中药杂志》.2009,第30卷(第11期),第77-78页. |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101759436B1 (en) * | 2015-05-22 | 2017-07-19 | 성균관대학교산학협력단 | Composition comprising Pogostemonis Herba extract for preventing or treating liver damage |
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