CN102961369A - New medicinal application of curdione - Google Patents
New medicinal application of curdione Download PDFInfo
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- CN102961369A CN102961369A CN 201210486958 CN201210486958A CN102961369A CN 102961369 A CN102961369 A CN 102961369A CN 201210486958 CN201210486958 CN 201210486958 CN 201210486958 A CN201210486958 A CN 201210486958A CN 102961369 A CN102961369 A CN 102961369A
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- curdione
- hypertension
- medicinal application
- blood pressure
- new medicinal
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention belongs to the field of biomedicine, relates to new application of curdione serving as a Chinese medicinal extract in hypertension resistance in vivo, and also describes a curdione-containing medicinal composition for preventing and treating hypertension.
Description
Technical field
The invention belongs to biomedicine field, relate to the new purposes of antihypertensive function in the curdione body.
Background technology
Hypertension (hypertensive disease) is a kind of chronic disease take the lasting rising of arteriotony as main manifestations, often cause the pathological changes of the vitals such as the heart, brain, kidney and corresponding consequence occurs, hypertension belongs to " headache ", " dizzy " category of the traditional Chinese medical science.The blood pressure standard that World Health Organization's suggestion is used is: the normal adult systolic pressure should be less than or equal to 140 mmHg, and diastolic pressure is less than or equal to 90 mmHg; Systolic pressure is between 141-159 mmHg, and diastolic pressure is borderline hypertension between 91-94 mmHg.
Doctor trained in Western medicine is emphasized individualized treatment, and the traditional Chinese medical science is then paid attention to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Western medicine hypertension adopts the index treatment, often too is concerned about an index of hypertension therapeutic, i.e. blood pressure values index, and under treatment-resistant, it is normal to seem the blood pressure index, in fact easily repeatedly.On theory of Chinese medical science, Chinese medicine because row neutralization, in just, the road of middle row, in hypertensive control, the conditioning viscera function is prevented and treated complication, and its relatively unique " treating both the principal and secondary aspects of a disease " advantage is arranged.Treatment by Chinese herbs mainly is environment in the blood disorderly in adjusting body, repairs impaired blood vessel wall, improves oxygen content, recovers injured cranial nerve cell, the adjustment vital organs of the human body, and qi blood balance, dredging the meridian reaches equilibrium between yin and yang.Common blood pressure lowering Chinese patent medicine has An ' gong blood pressure-reducing ball, Chinese hawthorn blood-pressure-reducing capsule, compound recipe antelope angle hypertension pill, chiang ya wan, chrysanthemum publicly price-reduction tabletting, Bezoar pill for lowering blood pressure etc.; Common Chinese hypotensor has Ramulus Uncariae Cum Uncis, Folium Apocyni Veneti, Radix Puerariae, the Radix Astragali etc.
Summary of the invention
The object of the present invention is to provide the new purposes of curdione in resisting hypertension.
Further, be used for preventing and treating the hypertensive pharmaceutical composition that contains curdione.
Curdione can effectively reduce blood pressure, and controls preferably the systolic pressure of spontaneous hypertensive rat (SHR).
The specific embodiment
Embodiment 1. curdione hypotensive activities
Curdione is available from Shenyang Long Pu Science and Technology Ltd., purity＞90% in the present embodiment.
10～12 week spontaneous hypertensive rats in age (SHR) are pressed the blood pressure grouping, and concrete dosage sees Table 1, and administration is the arteria caudalis pressure measurement after 7 days.
Statistical analysis: measurement data mean+SD
Expression, t check between relatively employing group of data between two groups.Take P＜0.05 as the significance standard.
The result: curdione can effectively reduce the SHR rat blood pressure, and relatively there were significant differences (P＜0.05) with model control group, sees Table 1.
Table 1. curdione successive administration is on the impact of SHR rat blood pressure
Compare with model control group
△P＜0.05.
Claims (2)
1. the new purposes of a Chinese medicine extract is characterized in that: the new purposes of antihypertensive function in the curdione body.
2. the new purposes of a kind of Chinese medicine extract according to claim 1 is characterized in that: be used for preventing and treating the hypertensive pharmaceutical composition that contains curdione.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210486958 CN102961369A (en) | 2012-11-26 | 2012-11-26 | New medicinal application of curdione |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210486958 CN102961369A (en) | 2012-11-26 | 2012-11-26 | New medicinal application of curdione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102961369A true CN102961369A (en) | 2013-03-13 |
Family
ID=47791989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210486958 Pending CN102961369A (en) | 2012-11-26 | 2012-11-26 | New medicinal application of curdione |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102961369A (en) |
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2012
- 2012-11-26 CN CN 201210486958 patent/CN102961369A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130313 |