CN102949531A - Health-care product tablet for treating acne and preparation method thereof - Google Patents

Abstract

The invention discloses a health-care product tablet for treating acne and a preparation method of the health-care product tablet. The health-care product tablet contains the following raw material medicinal components in parts by weight: 30 parts of flos lonicerae, 30 parts of dandelion, 15 parts of herba corydalis bungeanae, 9 parts of radix scutellariae, 9 parts of cortex phellodendri, 9 parts of fructus gardeniae, 15 parts of radix rehmanniae, 15 parts of cortex moutan, 15 parts of radix salviae miltiorrhizae, 15 parts of radix arnebiae seu lithospermi, 9 parts of spina gleditsiae and 9 parts of radix angelicae. The related health-care product tablet in the invention has the effects of dispelling wind and dissipating heat, eliminating pathogenic factors, resolving dampness and clearing heat, regulating vital energy and moistening dryness, clearing heat and removing toxicity and cooling blood and dissipating blood stasis, and is used for treating the symptoms including acne, etc. A traditional Chinese medicinal composition of the health-care product tablet has the advantages of being fast to absorb, high in bioavailability, fast in speed of reaching the effective blood concentration, accurate in qualification and stable in quality, free from dependency and the like, and conventional equipment can finish the production of the health-care product tablet.

Description

A kind of troche of health products that is used for the treatment of acne and preparation method thereof

Technical field

The invention belongs to field of health care products, relate to a kind of troche of health products for the treatment of Acne treatment, particularly a kind of troche of health products that is used for the treatment of acne and preparation method thereof.

Background technology

Acne is the normal physiological phenomenon of a kind of adolescence, multiple adolescence man, the pilosebaceous chronic inflammation disease of woman be born in, got acne a lot of people can not be worked normally with study, because the age of long acne just in time is the period that they take notice of own appearance most.Chinese medicine claims acne to be: " rosacea caused by lung-wind ", " pimples ", how partially contain because of the body heat in blood or insufficiency of the spleen phlegm-damp in stop, meet again the pungent delicious food of diet, fried barbecue, the product of the large hot tonifying YANG of nourishing, or exopathogen invading the interior heat-transformation, psychentonia, cosmetics are improper etc., cause damp-heat gluing each other, interior-heat dryness of the intestine, blood stasis heat-transformation.At present, a lot of products of the existing Acne treatment in market are cured the symptoms, not the disease, and reach the effective blood drug concentration time long, easily form dependency, and toxic and side effects is large, and dosage is large.And product of the present invention has overcome above shortcoming, have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.

Summary of the invention

The purpose of this invention is to provide a kind of troche of health products that is used for the treatment of acne and preparation method thereof, it has wind-dispelling heat-dissipating, leads tiltedly and goes out, and the removing dampness heat clearing away is regulated the flow of vital energy and moisturized, heat-clearing and toxic substances removing, and the loose effect of becoming silted up of removing heat from blood is used for the diseases such as acne.

Technical scheme of the present invention is: design a kind of troche of health products that is used for the treatment of acne, it is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 15 parts of Herba Violaes, 9 parts of Radix Scutellariaes, 9 parts of Cortex Phellodendris, 9 parts of Fructus Gardeniaes, 15 parts in the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Spina Gleditsiae, 9 parts of the Radixs Angelicae Dahuricae.

Above-mentioned a kind of preparation method that is used for the treatment of the troche of health products of acne, it may further comprise the steps:

1) by following weight ratio weighting raw materials: 30 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 15 parts of Herba Violaes, 9 parts of Radix Scutellariaes, 9 parts of Cortex Phellodendris, 9 parts of Fructus Gardeniaes, 15 parts in the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Spina Gleditsiae, 9 parts of the Radixs Angelicae Dahuricae;

2) get above-mentioned 12 flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.

Advantage of the present invention is: the Chinese medicinal tablet that contains among the present invention has wind-dispelling heat-dissipating, leads tiltedly and goes out, and the removing dampness heat clearing away is regulated the flow of vital energy and moisturized, heat-clearing and toxic substances removing, and the loose effect of becoming silted up of removing heat from blood is used for the diseases such as acne.Wherein the monarch drug Flos Lonicerae has the anti inflammatory detoxication effect in the prescription, and carbuncle furuncle, acute appendicitis lung abscess are had stronger loose carbuncle detumescence, heat-clearing and toxic substances removing, antiinflammation.Herba Taraxaci is sweet, and little hardship is cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.The Herba Violae clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.The Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.The Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication is except the hectic fever due to YIN-deficiency clearind deficient heat.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.The Cortex Moutan clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.Radix Arnebiae (Radix Lithospermi) cures mainly removing heat from blood, invigorates blood circulation the detoxifcation rash.Be used for that the heat in blood poison is contained, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood is used for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.

Health product of the present invention have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.

The specific embodiment

The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.

Embodiment 1

Described Chinese medicine preparation adopts following steps to make:

1) by following weight ratio weighting raw materials: 30 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 15 parts of Herba Violaes, 9 parts of Radix Scutellariaes, 9 parts of Cortex Phellodendris, 9 parts of Fructus Gardeniaes, 15 parts in the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Spina Gleditsiae, 9 parts of the Radixs Angelicae Dahuricae;

2) get above-mentioned 12 the flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, the filtration, be concentrated into relative density 1.10-1.20(80 ℃) thick paste, spray drying, for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.

The below is the clinical observation of Chinese medicine composition tablet (hereinafter to be referred as the embodiment 1) Acne treatment of this troche of health products preparation that is used for the treatment of acne of the present invention

1 data and method

1.1 physical data

Select patients with acne 80 examples receive treatment voluntarily, at 18～37 years old age, the mean age is 26.09 years old, and the course of disease 1 month is to 10a.Be divided at random treatment group 1, treatment group 2, treatment group 3, matched group, every group of 20 examples; Each is organized the patient age symptom and consists of without significant difference.Has comparability (P〉0.05).

1.2 Therapeutic Method

The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, one time 2,30 is a course for the treatment of.Treatment group 2 is used viaminate capsule, Huabang Pharmaceutical Co., Ltd., Chongqing, and each 25mg takes 3 every day; Treatment group 3 is used spironolactone, and Hangzhou Minsheng Pharmaceutical Group Co produces, each 20mg, and 2 times/d, 1 month is 1 course for the treatment of.

2 results

2.1 curative effect determinate standard

Observe treatment front and back skin lesion situation by 9 grades of point-scores of 3 degree.Treat 9 grades of front 3 degree, every l level is chosen as 1 minute.After the treatment, every reduction l level deducts 1 minute, if all disappearance then is 0 minute.

Mark * 100% before therapeutic index (%)=(mark after mark before the treatment-treatment)/treatment

Clinical cure: therapeutic index reaches more than 95%; Produce effects: therapeutic index 60%.95%.Effectively therapeutic index 20% one 59%; Invalid: therapeutic index＜20%.

2.2 therapeutic outcome

	Cure	Produce effects	Take a turn for the better	Invalid	Effective percentage
						Contrast				20	0
Treatment group 1	9	6	4	1	95%
						Treatment group 2	7	7	4	2	90%
Treatment group 3	6	8	3	3	85%

3 discuss

Modern medicine mainly is the androgen effect to the pathogenetic understanding of acne, and smegma increases, microbial action and inflammatory reaction in the pilosebaceous unit.Though acne can have a strong impact on Quality of Life as decreasing not threat to life of capacitive disease.Studies show that the affected degree of patients with acne psychology and asthma, epilepsy, diabetes chronic diseases are suitable.Adopt Chinese medicine to import administration, take the Chinese medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs as guideline, the prescription in conjunction with clinical treatment experience is by the effect of Serum Testosterone Levels, inhibition smegma and broad-spectrum antiseptic antiinflammatory in the control agent, thereby clinical symptoms and sign are alleviated or disappear, reach the healing purpose.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.

Claims (2)

1. troche of health products that is used for the treatment of acne is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 15 parts of Herba Violaes, 9 parts of Radix Scutellariaes, 9 parts of Cortex Phellodendris, 9 parts of Fructus Gardeniaes, 15 parts in the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Spina Gleditsiae, 9 parts of the Radixs Angelicae Dahuricae.

2. a kind of preparation method that is used for the treatment of the troche of health products of acne according to claim 1, it may further comprise the steps:

1) by following weight ratio weighting raw materials: 30 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 15 parts of Herba Violaes, 9 parts of Radix Scutellariaes, 9 parts of Cortex Phellodendris, 9 parts of Fructus Gardeniaes, 15 parts in the Radix Rehmanniae, 15 parts of Cortex Moutans, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Spina Gleditsiae, 9 parts of the Radixs Angelicae Dahuricae;

2) get above-mentioned 12 flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol; Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.