CN102948679A - Multifunctional mildew removal feed premixing agent with physical, chemical and biological mildew removal functions - Google Patents
Multifunctional mildew removal feed premixing agent with physical, chemical and biological mildew removal functions Download PDFInfo
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- CN102948679A CN102948679A CN2012102254107A CN201210225410A CN102948679A CN 102948679 A CN102948679 A CN 102948679A CN 2012102254107 A CN2012102254107 A CN 2012102254107A CN 201210225410 A CN201210225410 A CN 201210225410A CN 102948679 A CN102948679 A CN 102948679A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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Abstract
The invention discloses a multifunctional mildew removal feed premixing agent integrating physical, chemical and biological mildew removal functions. The multifunctional mildew removal feed premixing agent comprises the following components by weight parts: 0.8-1.5 parts of vitamin E, 0.4-1.2 parts of vitamin B1, 0.4-1.2 parts of vitamin B2, 0.1-0.2 part of vitamin B6, 0.1-0.2 part of vitamin B12, 300-450 parts of calcium propionate, 15-20 parts of copper sulfate, 0.3-0.5 part of mannan oligosaccharide, 0.5-0.8 part of antioxidant, 1-5 parts of food calling factors, and 519.4-681.4 parts of montmorillonite. The multifunctional mildew removal feed premixing agent has the effects of mildew removal, detoxication, toxicant elimination, soothing of the liver and the gallbladder, food calling, digestion promotion, immunological enhancement and the like.
Description
Technical field
The present invention relates to field of fodder, relate in particular to and a kind ofly have physics and chemistry and biological take off the mould multi-functional mould feed preblending agent that takes off.
Background technology
FAO (Food and Agriculture Organization of the United Nation) (FAO) investigation shows that the grain in the whole world 25% is subject to the pollution of mycotoxin.Mycotoxin contamination has brought huge economic loss to grain-production person, livestock and poultry cultivation person and food and feed processing enterprise.Show according to the investigation to Chinese mixed feed and feedstuff in 2003, the ratio that corn is polluted by T-2 toxin, aflatoxin, FT, ochratoxin is respectively up to 88%, 84%, 77% and 60%, all contain zearalenone and vomitoxin in nearly all corn sample, and all contain above six kinds of main mycotoxins in the mixed fodder sample more than 90%! Feeding can be caused livestock and poultry the phenomenons such as immunity reduces, disease increases, the speed of growth slows down to occur by the feed of mould contamination, occurs dead when serious.
In the past few decades, the output of Chinese animal food increases steadily, and meat, egg, milk yield had reached respectively 7,925 ten thousand tons, 2,765 ten thousand tons and 3,570 ten thousand tons in 2010.The quality of food and security have determined the market value of product, thereby it is more and more important to become.Because mycotoxin is one of key factor that affects Production of Livestock and Poultry power and product quality, the pollution of therefore controlling mycotoxin is very crucial.
Summary of the invention
The object of the present invention is to provide and a kind ofly have physics and chemistry and biological take off the mould multi-functional mould feed preblending agent that takes off, its purpose is: prevent the generation of Mycotoxins in Feed, the growth of mould fungus inhibition, prolong the storage period of feed, avoid livestock and poultry to be adversely affected, promote growth of animal; Improve colony's feed intake, efficiency of feed utilization and the speed of growth, reduce the generation of intestines problem; Reduce the Probability of ketosis of dairy cows and energy ingredient and the calcium ion of supplement feed.
The multi-functional mould feed preblending agent that takes off provided by the invention, its main component is vitamin E, Cobastab
1, Cobastab
2, calcium propionate and copper sulphate.In addition, also contain an amount of Cobastab
6, Cobastab
12, montmorillonite, manna oligosacchride, antioxidant and food calling factor etc.Each composition weight proportion is: vitamin E 0.8～1.5g/kg, Cobastab
10.4～1.2g/kg, Cobastab
20.4～1.2g/kg, Cobastab
60.1～0.2g/kg, Cobastab
120.1～0.2g/kg, calcium propionate 300～450g/kg, copper sulphate 15～20g/kg, manna oligosacchride 0.3～0.5g/kg, antioxidant 0.5～0.8g/kg, the food calling factor 1～5g/kg, montmorillonite 519.4～681.4g/kg.
Vitamin is the essential micro-content organism of animal body, plays an important role in growth of animal, metabolism, growth course.Cobastab
1Has the effect that improves a poor appetite, keeps neural normal activity; Cobastab
2Participating in the metabolism of carbohydrate, protein, nucleic acid and fat, can improve body to the utilization rate of protein, promote animal growth, simultaneously, participate in the growth metabolism of cell, is the necessary nutrient of body tissue metabolism and reparation; Vitamin E can promote the secretion of pituitary gonadotropic hormone, promotes generation and the activity of sperm, increases ovarian function, and ovarian follicle is increased, and lutein cell increases and strengthen the effect of progesterone, also can improve lipid-metabolism simultaneously.
Calcium propionate is the safe and reliable feed mould inhibitor that FAO's approval is used.In acid medium, all kinds of moulds, gram-Negative bacillus or aerobic bacillus there are stronger inhibitory action, can also suppress the generation of aflatoxin, and harmless to saccharomycete; In addition, this product is the same with other fat can be absorbed by people and animals by metabolism, and supplies with the essential calcium of people and animals.
Montmorillonite has powerful adsorption capacity to mycotoxin, has been widely used in feed and has taken off mould.Used montmorillonite is nanometer materials among the present invention, granularity is 30～300nm, large 100 times of the common goods of surface area ratio, has extremely strong interlayer ion exchanging orientation adsorption capacity, to the absorption affinity of aflatoxin, zearalenone, hyperplasia fusarium, reddish brown ochratoxin etc. all more than 90%, various mycotoxins can be fixed and lose pathogenecity, excrete with enterocinesia; Simultaneously, can with alimentary canal mucus protein electrostatical binding, increase the mucus amount and also improve the mucus quality, improve cohesive force and the elasticity of mucus, thereby gastrointestinal mucosal played protection and repair, promote the absorption of nutriment.
Copper sulphate has important effect to animal body, adds copper sulphate in daily ration, can effectively prevent and treat the symptoms such as livestock and poultry anaemia, tetraparesis, bone undergrowth, arthrocele, osteoporosis, growth retardation, heart failure, stomach and intestine disorder; Also can promote the growth of livestock and poultry and aquatic livestock, strengthen resistance against diseases, improve efficiency of feed utilization; Also can improve wool production and improve the hair quality sheep, pig is had similar antibiotic growth promoting function.
The specific embodiment
The present invention is described in further detail by following examples.Need to prove: following embodiment is illustrative, rather than restrictive, can not limit protection scope of the present invention with following embodiment.
Embodiment 1
A kind of have physics and chemistry and biological take off the mould multi-functional mould feed preblending agent that takes off, and every 1kg product consists of the following composition: vitamin E 0.8g, Cobastab
10.5g, Cobastab
20.45g, Cobastab
60.1g, Cobastab
120.1g, calcium propionate 300g, copper sulphate 15g, manna oligosacchride 0.4g, antioxidant 0.5g, food calling factor 3g, all the other are montmorillonite.
A kind of have physics and chemistry and biological take off mould multi-functional production method of taking off mould feed preblending agent, may further comprise the steps:
A, by the prescription requirement take by weighing various raw materials;
B, with vitamin E, Cobastab
1, Cobastab
2, Cobastab
6, Cobastab
12, calcium propionate, copper sulphate, manna oligosacchride, antioxidant and the food calling factor mix, and obtains once mixture;
C, in once mixture, add montmorillonite and mix, namely obtain finished product.
The embodiment 1 described multi-functional mould feed preblending agent that takes off is applicable to feed and takes off mould, piglet and chick etc.Adding proportion is 0.1%.
Embodiment 2
A kind of have physics and chemistry and biological take off the mould multi-functional mould feed preblending agent that takes off, and every 1kg product consists of the following composition: vitamin E 0.8g, Cobastab
10.4g, Cobastab
20.4g, Cobastab
60.1g, Cobastab
120.1g, calcium propionate 350g, copper sulphate 17g, manna oligosacchride 0.3g, antioxidant 0.6g, food calling factor 5g, all the other are montmorillonite.
Production method is with embodiment 1.
The embodiment 2 described multi-functional mould feed preblending agents that take off are applicable to pork pig, broiler chicken and laying hen etc.Adding proportion is 0.1%.
Embodiment 3
A kind of have physics and chemistry and biological take off the mould multi-functional mould feed preblending agent that takes off, and every 1kg product consists of the following composition: vitamin E 1g, Cobastab
10.4g, Cobastab
20.4g, Cobastab
60.2g, Cobastab
120.2g, calcium propionate 400g, copper sulphate 18g, manna oligosacchride 0.5g, antioxidant 0.6g, food calling factor 2g, all the other are montmorillonite.
Production method is with embodiment 1.
The embodiment 3 described multi-functional mould feed preblending agents that take off are applicable to boar, plant chicken, milk cow and ermine fox etc.Adding proportion is 0.1%.
1 one kinds of test examples have physics and chemistry and biological taking off mould multi-functionally taken off mould feed preblending agent to the impact of piglet growth performance.
1. materials and methods
1.1 for examination pig and grouping
Two processing are established in this test, and each processes three repetitions, according to the principle of " parity is consistent, body weight is close, male and female half and half ", with 60 random packet of health " DLY " tri-crossbreeding of 28 ages in days wean.Test is 4 weeks by a definite date.The conventional compound premix of control group fed, the basal diet composition sees Table 1.This adds embodiment 1 described premix to test group on control group basal diet basis.
The composition of table 1 basal diet
| Corn/% | 56.15 | Choline Chloride/% | 0.10 |
| Expanded soybean/% | 8.00 | Salt/% | 0.10 |
| Dregs of beans/% | 16.00 | Trace mineral supplement/% | 2.00 |
| Fish meal/% | 5.50 | Antibiotic/% | 0.02 |
| Milk powder/% | 3.00 | Wheat bran/% | 2.00 |
| Rapeseed oil/% | 2.00 | Rapeseed dregs/% | 3.00 |
| Calcium carbonate/% | 0.60 | Sweet flavouring agent/% | 0.11 |
| Calcium monohydrogen phosphate/% | 1.00 | Sodium acid carbonate/% | 0.50 |
| B B-complex/% | 0.08 | Amount to | 100.00 |
1.2 basal diet and feeding and management
Test pig is beaten overbit, feed in same semi-open double-row hog house.Duration of test, all pig free choice feeding and drinking-water, well-ventilated in the house, temperature and humidity is controlled according to raising rules, in time clears up fecaluria, and carries out disinfection.
1.3 performance test
Record the situations such as test pig appetite, spirit, ight soil, morbidity every day, record the feed intake of every day.Weekly weighing test pig body weight, calculate following production performance index:
Feed intake (ADFI): the surplus material of the front receipts of feeding every morning, clearing in a day are once;
Daily gain (ADG): weigh weekly once, survey weekly average daily gain;
Material anharmonic ratio (F/G): average feed intake (kg)/weekly average weight gain (kg) weekly;
Diarrhea rate (diarrhea ratio): a diarrhoea number/total number of test.
1.4 data are processed
Test data represents with average ± standard deviation, carries out one-way analysis of variance.All data are carried out Treatment Analysis with SPSS statistics software.
2. result of the test
Duration of test, each is organized test pig and incidence all do not occurred, searches for food, ight soil etc. is all normal.But compare with the control group test pig, test group piglet grazing speed is obviously very fast, and hair color is brighter, and Incidence of Diarrhea is lower.Each group weightening finish of duration of test, search for food and the situation such as Incidence of Diarrhea sees Table 2 and table 3.
Table 2 test group and control group production performance are relatively
| Index/kg | ? | The last week | The first two week | First three week | Around front | The full phase |
| Daily gain | Control group | 0.216±0.009 a | 0.243±0.005 a | 0.282±0.012 a | 0.307±0.022 a | 0.314±0.013 a |
| Daily gain | Test group | 0.223±0.015 a | 0.261±0.019 a | 0.310±0.029 a | 0.354±0.025 b | 0.356±0.014 B |
| Feed intake | Control group | 0.423±0.022 a | 0.502±0.018 a | 0.603±0.013 a | 0.669±0.026 a | 0.734±0.024 a |
| Feed intake | Test group | 0.396±0.020 a | 0.497±0.012 a | 0.584±0.017 a | 0.673±0.019 a | 0.738±0.017 a |
| Feedstuff-meat ratio | Control group | 1.96±0.09 a | 2.07±0.09 a | 2.14±0.12 a | 2.19±0.17 a | 2.34±0.12 a |
| Feedstuff-meat ratio | Test group | 1.78±0.14 b | 1.85±0.14 b | 1.89±0.12 b | 1.91±0.18 b | 2.07±0.09 B |
Table 3 test group and control group weightening finish are compared with diarrhea rate
| Index | Control group | Test group |
| First starting weight/kg | 8.15±0.20 a | 8.11±0.13 a |
| End weight/kg | 20.33±0.89 a | 22.21±1.27 b |
| Diarrhea rate/% | 10.00 | 3.33 |
Annotate: the data shoulder marker tape of different disposal has identical lowercase alphabet differential different not remarkable (p ﹥ 0.05), with different lowercase alphabet differentials different significantly (p ﹤ 0.05), when lowercase and capitalization do not represent difference extremely significantly (p ﹤ 0.01) simultaneously.
As can be seen from the above table, whole duration of test, control group and test group feed intake are without obvious difference, but from 4th week, the test group weight gain of piglets is obviously very fast, compares significant difference (p ﹤ 0.05) with control group; Duration of test, control group piglet daily gain is 0.314kg, and test group is 0.356kg, and the two compares difference extremely significantly (p ﹤ 0.01), and gaining effect is obvious.In the whole process of the test, the control group feedstuff-meat ratio all is significantly higher than test group, illustrates that test group pig starter feed utilization rate is higher, and gaining effect is obvious.
In sum, compare with present commercially available feed pre-mixing material, embodiment 1 is described multi-functionally to be taken off mould feed pre-mixing material and can obviously improve the speed of growth of weanling pig, improves efficiency of feed utilization, reduce the grice diarrhoea incidence, have the effect that significantly improves weaned piglets.
2 one kinds of test examples have physics and chemistry and biological taking off mould multi-functionally taken off mould feed preblending agent to the impact of performance in layers.
1. materials and methods
1.1 for examination animal and grouping
Test selects 120 body conditions good, laying rate and body weight close 35 age in week commoity layer roman, be divided at random two groups of test group and control groups, the control group fed corn-soybean meal diet, composition sees Table 1, test group is added embodiment 2 described premixes.
Table 1 basal diet forms
| Composition | Content/% | Composition | Content/% |
| Corn | 56.0 | The alcohol albumen powder | 5.0 |
| Dregs of beans | 14.6 | Corn protein powder | 2.0 |
| The dish dregs of rice | 3.4 | Stone flour | 8.2 |
| Peanut cake | 3.0 | Zeolite | 1.0 |
| Fish meal | 2.0 | Calcium monohydrogen phosphate | 1.8 |
| Dusty yeast | 2.4 | Premix | 0.6 |
1.2 feeding and management
In experimental period, immune programme for children carries out immunity routinely.Two groups of chickens all adopt identical conventional method to raise.Illumination every day keeps 16h, and humiture is suitable in the house.Regularly receive egg every day, Egg Production of Laying Hens quantity, egg size, feed consumption, recording occurring continuously two months respectively organized in record.
2. result of the test
Table 2 control group and test group performance in layers are relatively
| Project | Control group | Test group |
| Laying rate/% | 78.62±2.41 a | 88.57±3.29 b |
| Average egg weight/g | 59.02±0.89 a | 59.33±0.91 a |
| Day egg production/g/ only | 46.71±1.25 a | 49.04±1.45 a |
| Daily ingestion amount/g/ only | 117.52±4.47 a | 118.81±5.26 a |
| Feedstuff-egg ratio | 2.54±0.12 a | 2.38±0.24 b |
| Death rate/% | 5.00 | 3.33 |
Annotate: represent that with data line lowercase difference person two groups of data compare significant difference (p ﹤ 0.05), identical person represents that two groups of data compare difference not remarkable (p ﹥ 0.05).
As can be seen from Table 2, the control group laying rate is 78.62%, and test group is 88.57%, and test group contrast group improves 12.65%, and the two compares significant difference (p ﹤ 0.05).The control group feedstuff-egg ratio is 2.54, is significantly higher than test group (2.38), and the multi-functional laying rate that mould feed preblending agent can significantly improve laying hen of taking off is described, simultaneously, but the Effective Raise price of deed.
3 one kinds of test examples have physics and chemistry and biological taking off mould multi-functionally taken off mould feed preblending agent to the impact of reproduction performance of gestation sow.
1. materials and methods
1.1 for examination pig and grouping
Select close 40 of the sows of growing up of parity (2～3 tire), body condition, be divided into successively 2 groups according to the breeding order, 20 every group, identical Duroc boars remating.
1.2 feeding and management
Duration of test, the test sow diets is corn-soybean meal diet.With reference to NRC(1998) " nutritional need of pig ", basal diet such as the table 1 of design experiment pig.This adds embodiment 3 described premixes to the test group sow diets on the basis of control group basal diet.
The composition of table 1 basal diet
| The gestation daily ration | The lactation daily ration | |
| Corn/% | 58 | 59 |
| Wheat bran/% | 23 | 18 |
| Dregs of beans/% | 13 | 17 |
| Fish meal/% | 2 | 2 |
| Premix/% | 4 | 4 |
1.3 detection index
The product of every group of test sow young mean alive, nascent litter weight, first repiece counterpoise, wean in 28 days young number alive and weight of weaning litter are detected, and analyze the comprehensive index of reproduction of respectively organizing sow.
2. result of the test
Duration of test, the test sow is diseases not all, and the situations such as diet, spirit are all normal, the situation such as generation miscarriage.Test group and the control group sow condition of production see Table 2.
Table 2 control group and test group sow condition of production contrast table
| Index | Control group | Test group |
| Test sow/head | 20 | 20 |
| Produce the young mean/head of living | 10.5±1.9 a | 11.2±1.9 a |
| Nascent litter weight/kg | 14.36±2.56 a | 16.77±2.27 b |
| First repiece counterpoise/kg | 1.38±0.06 a | 1.47±0.10 b |
| Young number weaned in 28 days | 9.4±2.19 a | 10.8±2.12 b |
| 28 days weight of weaning litters | 65.91±8.27 a | 76.65±8.50 b |
| The comprehensive index of reproduction of sow | 109.55 | 124.45 |
Annotate: represent that with data line lowercase difference person two groups of data compare significant difference (p ﹤ 0.05), identical person represents that two groups of data compare difference not remarkable (p ﹥ 0.05);
Annotate: the comprehensive index of reproduction SPI=2.67NBA+1.87N of sow
28+ 0.97W
28, NBA is for producing the young number of living, N in the formula
28, W
28Be 28 days nests respectively wean young number and litter weight.
As can be seen from Table 2, control group and test group are on average produced the young number of living and are respectively 10.5 and 11.2, and when weaning to 28 ages in days, the young number of living is respectively 9.4 and 10.8, and test group contrast group is high by 14.89%, the two significant difference (p ﹤ 0.05).The nascent litter weight of control group is 14.36kg, and test group is 16.77kg, improves 16.78%, and the two is compared and is significant difference (p ﹤ 0.05); Simultaneously, test group piglet growth speed is obviously very fast, and when weaning to 28 ages in days, average litter weight is 76.65kg, and control group is the two difference of 65.91kg extremely significantly (p ﹤ 0.01).
In sum, compare with common premix product, add embodiment 3 described premixes in the in-pig daily ration and can obviously improve sow reproductive performance and promote the suckling pig growth, reduce the piglet death rate, have obvious economic benefit.
Claims (3)
1. one kind has physics and chemistry and biological takes off the mould multi-functional mould feed preblending agent that takes off, and it is characterized in that main component is vitamin E, Cobastab
1, Cobastab
2, calcium propionate and copper sulphate; In addition, also contain Cobastab
6, Cobastab
12, montmorillonite, manna oligosacchride, antioxidant and food calling factor etc.
2. the multi-functional mould feed preblending agent that takes off claimed in claim 1 is characterized in that the weight proportion of mentioned component is as follows: 0.8～1.5 part of vitamin E, Cobastab
10.4～1.2 parts, Cobastab
20.4～1.2 parts, Cobastab
60.1～0.2 part, Cobastab
120.1～0.2 part, 300～450 parts of calcium propionates, 15～20 parts in copper sulphate, 0.3～0.5 part of manna oligosacchride, 0.5～0.8 part of antioxidant, 1～5 part of the food calling factor, all the other weight are supplied by montmorillonite, and concrete content is 519.4～681.4 parts.
3. claim 1 or the 2 described multi-functional mould feed preblending agents that take off is characterized in that both can directly applying to the feed that goes mouldy, and also can make an addition to the control that is used for livestock and poultry in the feeds of the animals such as livestock and poultry.
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| CN104686798A (en) * | 2015-01-25 | 2015-06-10 | 山东绿都安特动物药业有限公司 | Multifunctional mildew removal feed premix with physical, chemical and biological mildew removal function |
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| CN105639062A (en) * | 2014-11-11 | 2016-06-08 | 天津嘉瑞生物科技有限公司 | Special feed additive for mink and fox as well as preparation method thereof |
| CN110353093A (en) * | 2019-08-30 | 2019-10-22 | 襄阳求是动物科技有限公司 | Comprehensive detoxification AFB1Broiler fodder and preparation method thereof |
| CN115812854A (en) * | 2022-05-07 | 2023-03-21 | 中国农业大学 | Feed additive and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104664133A (en) * | 2013-12-03 | 2015-06-03 | 天津市中敖饲料有限公司 | Special vitamin feed additive for egg-type breeding chicken and preparation method for special vitamin feed |
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| CN104686798A (en) * | 2015-01-25 | 2015-06-10 | 山东绿都安特动物药业有限公司 | Multifunctional mildew removal feed premix with physical, chemical and biological mildew removal function |
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| CN105010760B (en) * | 2015-08-14 | 2018-11-06 | 安吉高纯蒙脱石有限公司 | A kind of wide spectrum feed montmorillonite takes off mould dose and preparation method thereof and application method |
| CN110353093A (en) * | 2019-08-30 | 2019-10-22 | 襄阳求是动物科技有限公司 | Comprehensive detoxification AFB1Broiler fodder and preparation method thereof |
| CN115812854A (en) * | 2022-05-07 | 2023-03-21 | 中国农业大学 | Feed additive and application thereof |
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