CN102921076A - Injection sleeve group - Google Patents

Injection sleeve group Download PDF

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Publication number
CN102921076A
CN102921076A CN2012104524399A CN201210452439A CN102921076A CN 102921076 A CN102921076 A CN 102921076A CN 2012104524399 A CN2012104524399 A CN 2012104524399A CN 201210452439 A CN201210452439 A CN 201210452439A CN 102921076 A CN102921076 A CN 102921076A
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China
Prior art keywords
optical fiber
pin
tissue
detection device
injection
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CN2012104524399A
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Chinese (zh)
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江台安
张寅�
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Individual
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Individual
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Priority to CN2012104524399A priority Critical patent/CN102921076A/en
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Abstract

The invention provides an injection sleeve group which comprises a hollow primary needle used for puncturing an individual tissue, and a draw-change type hollow secondary needle, wherein at least one optical fiber is arranged in a central hole of the secondary needle. The draw-change type hollow secondary needle provided with the optical fiber is inserted into the hollow primary needle to form a puncturing sleeve group by means of combination of the primary needle and the secondary needle; the optical fiber is connected to a light source and a light detection device which detects optical properties of the individual tissue so as to provide state information of the tissue; and the puncturing sleeve group is inserted into an individual, and by means of the state information of the tissue provided by the light detection device, a position where a sharp end of the puncturing sleeve group reaches can be judged and read. The injection sleeve group can accurately place an injection catheter on a specific position in a body of a subject, improves accuracy of a surgery or an anesthesia surgery, and reduces surgical risks of patients.

Description

Injection cover group
Technical field
The present invention relates to a kind of injection cover group, be applied to Minimally Invasive Surgery, the spinal cord peridural anesthesia is organized these clinical operations of identification, and such as postoperative analgesia or painless delivery, intestinal glues glutinous differentiation etc. in the abdominal operation.
Background technology
Mostly must rely on clinically at present anesthesia doctor's experience and technology to judge whether puncture needle arrives spinal epidural cavity.The anesthesia doctor removes to feel or experience the resistance of ligamenta flava by hands, be used as first important index with this.And the resistance of ligamenta flava is different and different along with age, sex and build etc., and for example, old old man's ligamenta flava elasticity is relatively poor.The anemia of pregnant woman who seldom moves or fat people, the resistance that its ligamenta flava tissue causes also may be less.If the anesthesia doctor feel of adding at that time is in poor shape, make the doctor be not easy impression and judge, just may wear out dura mater and cause operative failure, cause patient that the sequela such as headache are arranged after surgery.
Therefore, expectation can have a kind of effectively auxiliary detector, can be with the auxiliary judgment foundation of objective and science, help the anesthesia doctor when implementing peridural anesthesia, except relying on subjective experience and technology, other more objective standard and judgments also can be arranged, to increase the correctness of auxiliary doctor's detecting.
Summary of the invention
For this reason, technical problem to be solved by this invention is: a kind of injection cover group, utilize a quantifiable optical characteristics of judging standard detecting tissue, the reflected light values that tissue is subject to the rear gained of different wave length irradiation is quantized, so that improvement is performed a surgical operation or the degree of accuracy of anesthesia surgery, and reduces patient's operation risk.
So, the invention provides a kind of injection cover group that the syringe needle positioning function is provided, it utilizes the different optical characteristic of differentiating individual tissue to locate syringe needle, comprising: a middle aircraft carrier pin is used for the individual tissue of puncture; Gap pin in the swapping type comprises an optical fiber at least in its center hole, one of optical fiber end is connected to a light source and a smooth detection device, and this sub-pin is to be seated in the aforementioned middle aircraft carrier pin; A light detection device is used for the individual optical characteristics of organizing of detecting; And a light source, provide aforementioned smooth detection device required incident light source.It is single fiber, multicore fiber bundle, Y shape optical fiber beam or a plurality of optical fiber that the present invention injects the optical fiber in it of gap pin in the swapping type in the cover group, this optical fiber be can allow the light that sends from light source be communicated to sub-needle tip thorn to tissue, and reflected light that will this tissue is conveyed to light detection device.When this optical fiber only has when a branch of, this single beam is fine to be needed simultaneously as conduction incident illumination and catoptrical medium; If this number of fibers can be the importing approach of incident illumination with the optical fiber designs of a part then greater than for the moment, another part then is designed to catoptrical derivation approach.Because different tissue, because the difference of its constituent can show different optical characteristics, for example, light absorption value all can be different under different lambda1-wavelengths from reflected light values, so the light detection device that the present invention injects in the cover group utilizes this principle, the detecting group of individuals is woven in reflected light values or the fluorescent value ratio of different wave length, assists the position of judging that described female pin and sub-needle tip arrived with the information that this tissue aspect is provided.Further, if this will be injected the cover group when being applied to peridural anesthesia, then the research of reality is found according to the present invention, and the better reflected light values ratio that can whether arrive in order to differentiate needle point spinal epidural cavity is to be that the reflected light values of arbitrary wavelength among 610nm ~ 810nm is the reflected light values of arbitrary wavelength among 400nm ~ 600nm divided by lambda1-wavelength by lambda1-wavelength.And further, if take be organized in lambda1-wavelength in 610nm ~ 810nm the reflected light values during arbitrary wavelength divided by lambda1-wavelength the reflected light values during as 400nm ~ 600nm, then drawn ratio can be conducive to more greatly and differentiate the position of spinal epidural cavity.But in practical application, because at present can to send wavelength be wherein a kind of wavelength among the 610nm-810nm and the light source of the wherein a kind of wavelength among the 400nm-600nm for existing ready-made low-power other semiconductor lasers product or high brightness LED, therefore adopt the incident illumination of this two wavelength also can be comparatively convenient.
Light detection device among the present invention is to be set up on their own by user, makes it when the puncture needle needle point arrives particular organization, makes the attention device of its connection initiatively send the signal that puts in place, allows attention device inform user with flash of light or song.
The present invention injects substituting the formula pin and then can be drawn out of in the cover group when it arrives destination organization, and is replaced by an injection catheter, and after injection catheter was sent in the subject along female pin smoothly, female pin also was removed subsequently, to finish the storing of injection catheter.Aforementioned injection catheter is general injection catheter, the liquid infusions such as foreign substance such as anesthetics or normal saline solution can be entered in the subject.
In the method for described locating injection syringe needle, the optical characteristics that this light detection device is detected is that material is at the reflected light values ratio of different wave length, and user can set up this light detection device on their own, make it when judging that described puncture cover group arrives destination organization, can inform user with sound and light signal or other warning ways.In this, the user gets final product the formula pin of substituting that will contain optical fiber and extracts out and with an injection catheter it is replaced, and more female pin is detached subsequently, can accurately injection catheter be placed in thus the ad-hoc location in the subject.In addition, this method also can be organized disclosed various assembly by described cover and finishes.
Description of drawings
Fig. 1 is human body ridge vertical section schematic diagram outwardly;
Fig. 2 is optical fiber detecting mode schematic diagram;
Fig. 3 is for respectively organizing reflectance spectrum through the result schematic diagram to gained after the correction of light source light spectrum;
Fig. 4 is holocentric fibre bundle type light detection device running circuit diagram of the present invention;
Fig. 5 is multicore fiber bundle type light detection device running circuit diagram of the present invention.
The specific embodiment
Following embodiment further specifies the present invention.
Because different tissues can show different optical characteristics because of the difference of its constituent, for example light absorption value all can be different under different lambda1-wavelengths from reflected light values, therefore utilize this principle, traditional peridural anesthesia in conjunction with the optical detecting method, is improved the degree of accuracy of anesthesia surgery.
Fig. 1 is the human body ridge vertical section schematic diagram of (posterior) outwardly, vertebrae do not paint into, but linked groups's relative position anatomically shows with English alphabet.The pin of peridural anesthesia represents with blue pointed cone.Periosteum membrane is the periosteum of vertebrae, not necessarily can run in the progradation of pin.
Embodiment 1: utilize optical detecting to organize the injection cover group of aspect
Inject in the cover group in the present invention, female pin is to adopt general syringe needle, is a hollow design, can insert sub-pin of the present invention in it and also agree with mutually, and female needle tip can puncture into such as skin, muscle, fat or the biological tissues such as mucosa, ligamenta flava.Sub-pin is similarly a hollow design, but its center then is to insert fibre bundle, and at sub-pin with optical cement with optical fiber and sub-pin gummed, the external form of its pin is worn into the shape that is complementary with female pin, the optical fiber of another end is then received on the control circuit of light source and light detection device and necessity.
Fig. 2 is detecting mode schematic diagram of the present invention, the light that light source 210 sends among the figure by lens 220,230 or suitable Optical devices import optical fiber in the sub-pin 270, shine on tissue 240, and the light that tissue reflects can be transferred to by another arm 280 of Y shape optical fiber beam light detection device 250, afterwards light detection device again with the signal transmission that detects to processor 260, in addition datumization on processor 260 is to provide the user as basis for estimation.
Embodiment 2: utilize the pig experiment of puncturing
In pilot study(perspective study) in, take off linked groups after first others being done the piglets experiment and slaughtering piglets, obtain the reflectance spectrum of variant tissue in the mode of Fig. 2.Light source is xenon lamp among the figure, and lens import light source in the one microscopical object lens, makes light be focused into a point, imports in the arm of a Y shape fibre bundle.The optical fiber arrangement of this fibre bundle such as bottom-right graph: light color a branch of part 270 in center be travel path of incident light, and dark six bundle parts 280 are the reflected light path from organizing on every side, out enters a spectrogrph from another arm of Y shape optical fiber.Spectrogrph is organized reflectance spectrum input computer with this.Fig. 3 is that the reflectance spectrum process of each tissue is to the result of gained after the correction of light source light spectrum.
Learnt by Fig. 3, if in arbitrary tissue with the reflected light values of the 650nm reflected light values divided by 532nm, the ratio of ligamenta flava is all greater than 3, remaining tissue is all less than 2, thus, this just can become the excellent method of an identification identification ligamenta flava position.In the experiment of reality, we expect once pin enters spinal epidural cavity, and this ratio will inevitably descend suddenly (light can be from the spinal dura mater surface reflection, and its ratio is less than 2), and just can stop pin propelling this moment, because needle point has arrived desired empty cavity position.At this moment just sub-pin can be extracted out, carry out the storing of epidural cavities conduit pipe.Among Fig. 3, substantially, 650nm should be larger to the ratio of 532nm than 650nm to the ratio of 580nm, and the reason why we select 650nm and 532nm wavelength is to have the low-power other semiconductor lasers of ready-made commercial product to use.
Embodiment 3: the design of light detection device
Fig. 4 realizes our purpose with the detecting system that above photoelectric subassembly of conclusion work is integrated.
Control circuit 420 among Fig. 4 is to control two groups of lasers, do mutually anti-phase regulating type pulse output as an example of 650nm, 532nm example, namely when 650nm laser light source 431 was opened, 532nm laser light source 441 just was closed condition (OFF State), and vice versa.These two groups of laser light are divided into twice optical path 450 and 460 via optical path 430, optical path 440 through behind the spectroscope 435.Light can enter optical fiber 451 through lens or suitable optical module 437 at optical path 450 and be led into tissue, and turning back to lens or suitable optical module 437, spectroscope 436 along original route after reflection reflexes to lens or suitable optical module 438 again.Delivering to light detection device 472 after lens or suitable optical module 438 are collected light does to reach general amplifier 473 after prime is amplified again signal is done filtering and amplification.Afterwards, just deliver to control circuit 420 and do relevant signal processing, with 650 nm the ratio of 530 nm is presented on the signal display 410 at last.Simultaneously, also can establish an alert news threshold values on circuit, namely when 650 nm surpassed 3 to the ratio of 532 nm, control circuit 420 just sent a kind of sound alert news; When this ratio is reduced to 2 down suddenly by 3, send again another alert news.The former is that the caution probe has reached ligamenta flava, and the latter warns probe and reached spinal epidural cavity.Send 650 nm or 532 nm light to the tissue simultaneously, spectroscope 436 also light mat reflecting mirror 461 that it is a part of is directed at another light detection device 462 and amplifies signal, with the monitoring as light intensity.
The structure of Fig. 4 is different from Fig. 2, and reason is in pilot study(perspective study) in, our usefulness be thicker Y shape fibre bundle.But at the sub-pin of the anesthesia of reality, can't resembling among the figure two, the fibre bundle that design is divided in the cavity that multi beam penetrates sub-pin.Therefore, we will use (a) single plastic optical fiber, or (b) oversensitive glass optical fiber bundle, single beam optical fiber do simultaneously incident and receive the medium of reflection signal.So, the interface of relevant optical module must coating anti reflection film.
Fig. 5 is that another is selected, namely in the situation that the number of fibers in the sub-pin greater than one, we can allow the optical fiber of a part only bring the leaded light of making light source, the optical fiber of another part is then brought the leaded light of organizing reflected light to enter light detection device.Its operation principle is similar to Fig. 4.
The main idea of the present invention is to utilize each tissue of organism to form the difference of part, each tissue has the optical characteristics of different absorptions and reflection and fluorescence Raman to the different wave length line, utilize the light source of several different-wavebands to be projeced in the biological tissue through optical fiber, which kind of tissue is the optical characteristics of differentiating tissue come the identification puncture needle in or can reach accurately specific location purpose on the surface of biological tissue, organ, specifically treats or performs the operation.
This technical scheme can be used specific light source irradiation tissue, and identification tissue oxygenation amount, or bioluminescence reach distinguishing of harmful structure, the effect that the diagnoses and treatment that progresses greatly is treated.
For example, intestinal is sticking glutinous as example in Wicresoft's abdominal operation, and the middle-aged women great majority have the sticking glutinous phenomenon of intestinal, must beat an air-filled pore at abdominal part first before Minimally Invasive Surgery, allows the abdominal part inflation, and convenient the operation carried out.Be stained with glutinous place if the doctor beats in first hole at intestinal, this moment, intestines were damaged at once, and Minimally Invasive Surgery i.e. failure.Sufferer must be opened the large tracts of land wound at abdominal part, and this is not that the doctor expects at once.If the doctor with regard to this technology, just can find that immediately signal is unusual in the piercing process with using the described technical scheme of the present embodiment when first inflates the hole at cutter, be stained with in a organized way glutinous phenomenon, the risk of both having exempted the Minimally Invasive Surgery failure by changing punch position so.
Again for example, in the emergency and severe disease first aid, the doctor often can not find sufferer table superficial part position blood vessel, uses the described technical scheme of the present embodiment, so, and by observing the optical characteristics difference between blood vessel wall and the muscular tissue, the tram that can tell fast blood vessel.
Again for example, specific medication precisely is shipped to particular tissue surface or in-house application.Specific medication index target medicine, the gold nanoparticle ball, fluorescence medicament etc., use the described technical scheme of the embodiment of the invention, by with drug delivery to specific tumors, long-time growth of following the trail of the living animal interior tumor cell reaches the reaction to Drug therapy, even comes traget antibody, small-molecule drug to observe distribution and metabolism in animal body by fluorescence.
The below is described in detail the present embodiment technical scheme take spinal dura mater anesthesia as real case:
Spinal dura mater anesthesia (epidural anesthesia) is injected local anesthetic in the spinal epidural cavity (epidural space), spinal nerves is done the reversibility blocking-up, to obtain the method for anaesthetic effect, be also referred to as spinal dura mater Interruption (epidural block), this is one of normal half body anesthesia of using of surgical operation.For the anesthesia doctor, when carrying out this anesthesia surgery, the problem of most critical is exactly the position that is accurately to differentiate spinal epidural cavity.At first with the viewpoint of anatomical physiology, as shown in Figure 1, spinal epidural cavity is a potential chamber between spinal dura mater (dural mater) and ligamenta flava (ligamentum flavum), a very narrow cavity, the detecting when also therefore causing this anesthesia of execution and the degree of difficulty of location.This cavity has the different difference of width because people's build is different with the age again, and is normal, and the widest at waist center place, its width is 3 ~ 6mm, and only is 1 ~ 5mm at middle chest.If accidentally wear out dura mater, gently then can cause the sequela such as patient's Headache (post-dural puncture headache, PDPH), heavy then the danger of infringement spinal cord is arranged, the therefore importance of correct puncture as can be known.
The present invention is described in detail, and obvious example is arranged, and any people who possesses basic skills in this field can both use it and do and variously substitute, modifies or improve, but clearly, these all can not separate with spirit of the present invention and invention scope.
Therefore, although should be appreciated that according to preferred embodiment and arbitrarily characteristics specifically disclose the present invention, know this skill person and still can revise and change the content that wherein discloses, suchlike modifications and variations are still in the present invention's claim.The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (7)

1. an injection cover group is characterized in that, comprising:
A middle aircraft carrier pin is used for the individual tissue of puncture; And
Gap pin in the swapping type comprises an optical fiber at least in its center hole.
2. injection cover group according to claim 1 is characterized in that, the formula pin of substituting that wherein contains optical fiber is drawn out of when female pin arrives the particular organization position, and is replaced by an injection catheter, and wherein injection catheter is general injection catheter.
3. injection cover group according to claim 1, it is characterized in that, described optical fiber is single fiber, multicore fiber bundle, Y shape optical fiber beam or a plurality of optical fiber, and the optical fiber group of wherein inserting gap pin in the swapping type can be a whole piece or is divided into several sections and is combined into an optical fiber group.
4. injection cover group according to claim 1 is characterized in that, also comprises:
One smooth detection device is used for the individual optical characteristics of organizing of detecting; And
One light source provides aforementioned smooth detection device required incident light source;
Wherein, described smooth detection device and light source are connected with optical fiber in the described sub-pin.
5. injection cover group according to claim 4 is characterized in that, described smooth detection device detects group of individuals and is woven in different wave length reflected light values ratio, assists to judge the location of described female pin and sub-needle tip with the information that this tissue aspect is provided.
6. injection cover group according to claim 4 is characterized in that, described light source can provide two or more different wave lengths.
7. injection cover group according to claim 6 is characterized in that, described light source is laser light.
CN2012104524399A 2012-11-13 2012-11-13 Injection sleeve group Pending CN102921076A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61261009A (en) * 1985-05-15 1986-11-19 Kawasumi Lab Inc Resin-curing process
JP2000312719A (en) * 1999-04-30 2000-11-14 Kazuhiro Ishizaka Light emitting type injection needle
CN1481908A (en) * 2003-07-18 2004-03-17 黄益富 Fiberoptic slider and transfusable fiberoptic needle using the same
TW200916135A (en) * 2007-10-15 2009-04-16 Univ Nat Yang Ming Spinal cord's epidural space detection by using fiber optic technology
CN201977895U (en) * 2011-01-30 2011-09-21 张清月 Gland syringe with light-guide puncture function
CN203090115U (en) * 2012-11-13 2013-07-31 江台安 Injection kit

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61261009A (en) * 1985-05-15 1986-11-19 Kawasumi Lab Inc Resin-curing process
JP2000312719A (en) * 1999-04-30 2000-11-14 Kazuhiro Ishizaka Light emitting type injection needle
CN1481908A (en) * 2003-07-18 2004-03-17 黄益富 Fiberoptic slider and transfusable fiberoptic needle using the same
TW200916135A (en) * 2007-10-15 2009-04-16 Univ Nat Yang Ming Spinal cord's epidural space detection by using fiber optic technology
CN201977895U (en) * 2011-01-30 2011-09-21 张清月 Gland syringe with light-guide puncture function
CN203090115U (en) * 2012-11-13 2013-07-31 江台安 Injection kit

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Application publication date: 20130213