CN203090115U - Injection kit - Google Patents

Abstract

The utility model provides an injection kit comprising a hollow main needle for puncturing an individual tissue, and an extraction type hollow secondary needle, wherein a central hole of the extraction type hollow secondary needle at least comprises an optical fiber. The extraction type secondary needle containing the optical fiber is inserted into the hollow main needle to combine a puncturing set; the optical fiber is connected to an optical source and an optical detector, and the optical detector is used for detecting the optical characteristics of the individual tissue so as to provide information of the tissue state sample; and the puncturing set is inserted into the individual, and the reaching position of the tip of the puncturing set is judged through the information of the tissue state sample provided by the optical detector. According to the injection kit disclosed by the utility model, an injection catheter can be precisely placed at a specific position inside the body of a person to be tested; and the precision of an operation or an anesthesia operation is improved, and the operation risk of a patient is reduced.

Description

Injection cover group

Technical field

This utility model relates to a kind of injection cover group, is applied to Minimally Invasive Surgery, and the spinal cord peridural anesthesia is organized these clinical operations of identification, as postoperative analgesia or painless delivery, and the resolution of sticking glutinous differentiation tumor of abdominal operation midgut and normal structure etc.

Background technology

Mostly must rely on anesthesia doctor's experience and technology to judge whether puncture needle arrives spinal epidural cavity at present clinically.The anesthesia doctor removes to feel or experience the resistance of ligamenta flava by hands, is used as first important index with this.And the resistance of ligamenta flava is different and different along with age, sex and build etc., and for example, old old man's ligamenta flava elasticity is relatively poor.Seldom Yun Dong anemia of pregnant woman or fat people, the resistance that its ligamenta flava tissue is caused is also possible less.If the anesthesia doctor feel of adding at that time is in poor shape, make the doctor be not easy impression and judge, just may wear out dura mater and cause operative failure, cause patient that sequela such as headache are arranged after surgery.

Therefore, expectation can have a kind of effectively auxiliary detector, can be with the auxiliary judgment foundation of objective and science, help the anesthesia doctor when implementing peridural anesthesia, except relying on subjective experience and technology, other more objective standard and foundations also can be arranged, to increase the correctness of auxiliary doctor's detecting.

The utility model content

For this reason, technical problem to be solved in the utility model is: a kind of injection cover group, utilize one quantifiablely to judge standard detecting optical properties of tissue, the reflected light values or the fluorescent value that tissue are subjected to different wave length irradiation back gained are quantized, so that improvement is performed a surgical operation or the degree of accuracy of anesthesia surgery, and reduces patient's operation risk.

So this utility model provides a kind of injection cover group that the syringe needle positioning function is provided, it utilizes the different optical characteristic of differentiating individual tissue to locate syringe needle, comprising: a middle aircraft carrier pin, and individual tissue is used to puncture; Gap pin in the swapping type comprises an optical fiber at least in its center hole, one of optical fiber end is connected to a light source and a smooth detection device, and this sub-pin is to be seated in the aforementioned middle aircraft carrier pin; A light detection device is used to detect individual optical properties of tissue; And a light source, provide aforementioned lights detection device required incident light source.Its interior optical fiber of gap pin is single fiber, multicore fiber bundle, Y shape optical fiber beam or a plurality of optical fiber in the swapping type in this utility model injection cover group, this optical fiber be can allow the light that sends from light source be communicated to sub-needle tip thorn to tissue, and reflected light that will this tissue is conveyed to light detection device.When this optical fiber has only when a branch of, this single beam is fine to be needed simultaneously as conduction incident illumination and catoptrical media; If this number of fibers can be the importing approach of incident illumination with the optical fiber designs of a part then greater than for the moment, another partly then is designed to catoptrical derivation approach.

Because different tissue, because of the difference of its constituent can show different optical characteristics, for example, light absorption value all can be different under different lambda1-wavelengths with reflected light values, so the light detection device that the present invention injects in the cover group utilizes this principle, the detecting individuality is organized in the reflected light values or the fluorescent value ratio of different wave length, assists the position of judging that described female pin and sub-needle tip arrived with the information that this tissue aspect is provided.Further, if this will be injected the cover group when being applied to peridural anesthesia, the discovering of reality according to the present invention then can be to be that the reflected light values of arbitrary wavelength among 610nm ~ 810nm is the reflected light values of arbitrary wavelength among 400nm ~ 600nm divided by lambda1-wavelength by lambda1-wavelength in order to differentiate preferable reflected light values ratio that whether needle point arrive spinal epidural cavity.And further, if to be organized in lambda1-wavelength is reflected light values when the reflected light values during arbitrary wavelength is 400nm ~ 600nm divided by lambda1-wavelength among 610nm ~ 810nm, then the ratio that is drawn can help differentiating the position of spinal epidural cavity more greatly and.But in practical application, because it is the wherein a kind of wavelength among the 610nm-810nm and the light source of the wherein a kind of wavelength among the 400nm-600nm that at present existing ready-made low-power other semiconductor lasers product or high brightness LED can send wavelength, therefore adopt the incident illumination of this two wavelength also can be comparatively convenient.

Described optical fiber is single fiber, multicore fiber bundle, Y shape optical fiber beam or a plurality of optical fiber, and the optical fiber group of wherein inserting gap pin in the swapping type can be a whole piece or is divided into several sections and is combined into an optical fiber group.

Injection cover group also comprises:

One smooth detection device is used to detect individual optical properties of tissue; And

One light source provides aforementioned lights detection device required incident light source;

Wherein, described smooth detection device and light source are connected with optical fiber in the described sub-pin.

Described smooth detection device is used to detect the ratio that individuality is organized in the different wave length reflected light values.

Described light source can provide the light of two or more different wave lengths.

Described light source is a laser light.

Light detection device in this utility model is to be set up on their own by user, makes it when the puncture needle needle point arrives particular organization, makes the attention device of its connection initiatively send the signal that puts in place, allows attention device inform user with flash of light or song.

Substituting the formula pin and when its arrival destination organization, then can be drawn out of in this utility model injection cover group, and replaced by an injection catheter, after injection catheter was sent in the subject along female pin smoothly, female pin also was removed subsequently, to finish the storing of injection catheter.Aforementioned injection catheter is general injection catheter, liquid infusions such as foreign substance such as anesthetics or normal saline solution can be gone in the subject.

In the method for described locating injection syringe needle, the optical characteristics that this light detection device is detected is the reflected light values ratio of material at different wave length, and user can set up this light detection device on their own, make it when judging that described puncture cover group arrives destination organization, can inform user with sound and light signal or other warning ways.In this, the user gets final product the formula pin of substituting that will contain optical fiber and extracts out and with an injection catheter it is replaced, and more female pin is detached subsequently, can accurately injection catheter be placed in the intravital ad-hoc location of experimenter thus.In addition, this method also can be organized disclosed various assembly by described cover and finishes.

Description of drawings

Fig. 1 is a human body ridge vertical section sketch map outwardly;

Fig. 2 is optical fiber detecting mode sketch map;

Fig. 3 is for respectively organizing reflectance spectrum through the result schematic diagram to gained after the correction of light source light spectrum;

Fig. 4 is this utility model holocentric fibre bundle type light detection device running circuit diagram;

Fig. 5 is this utility model multicore fiber bundle type light detection device running circuit diagram.

The specific embodiment

Following embodiment further specifies the present invention.

Because different tissues can show different optical characteristics because of the difference of its constituent, for example light absorption value all can be different under different lambda1-wavelengths with reflected light values, therefore utilize this principle, traditional peridural anesthesia in conjunction with the optical detecting method, is improved the degree of accuracy of anesthesia surgery.

Fig. 1 is the human body ridge vertical section sketch map of (posterior) outwardly, vertebrae do not paint into, but linked groups's relative position anatomically shows with English alphabet.The pin of peridural anesthesia is represented with blue pointed cone.Periosteum membrane is the periosteum of vertebrae, not necessarily can run in the progradation of pin.

Embodiment 1: utilize optical detecting to organize the injection cover group of aspect

Inject in the cover group in the present invention, female pin is to adopt general syringe needle, is a hollow design, can insert sub-pin of the present invention in it and also agree with mutually, and female needle tip can puncture into as skin, muscle, fat or biological tissues such as mucosa, ligamenta flava.Sub-pin is similarly a hollow design, but its center then is to insert fibre bundle, and at sub-pin with optical cement with optical fiber and sub-pin gummed, the external form of its pin is worn into the shape that is complementary with female pin, the optical fiber of end is then received on light source and light detection device and the necessary control circuit in addition.

Fig. 2 is a detecting mode sketch map of the present invention, the light that light source 210 is sent among the figure imports optical fiber in the sub-pin 270 by lens 220,230 or suitable Optical devices, shine on tissue 240, and the light that tissue is reflected can be transferred to light detection device 250 by another arm 280 of Y shape optical fiber beam, the device of light detection afterwards transfers to the signal that is detected on the processor 260 again, datumization in addition on processor 260 is to provide the user as basis for estimation.

Embodiment 2: utilize the pig experiment of puncturing

In pilot study(perspective study) in, take off linked groups after earlier others being done the piglets experiment and slaughtering piglets, obtain the reflectance spectrum of variant tissue in the mode of Fig. 2.Light source is an xenon lamp among the figure, and lens import light source in the one microscopical object lens, makes light be focused into a point, imports in the arm of a Y shape fibre bundle.The optical fiber of this fibre bundle is arranged as bottom-right graph: the center a branch of part 270 of light color be a travel path of incident light, and dark six to restraint parts 280 be reflected light path from organizing on every side, comes out to enter a spectrogrph from another arm of Y shape optical fiber.Spectrogrph is organized reflectance spectrum input computer with this.Fig. 3 is the result of the reflectance spectrum process of each tissue to gained after the correction of light source light spectrum.

Learnt that by Fig. 3 if with the reflected light values of the 650nm reflected light values divided by 532nm, the ratio of ligamenta flava is all greater than 3 in arbitrary tissue, remaining tissue is all less than 2, and thus, this just can become the excellent method that the ligamenta flava position is discerned in an identification.In the experiment of reality, we expect that once pin enters spinal epidural cavity this ratio will inevitably descend suddenly (light can be from the spinal dura mater surface reflectance, and its ratio is less than 2), just pin can be stopped this moment advancing, because of needle point has arrived desired empty cavity position.At this moment just sub-pin can be extracted out, carry out the storing of epidural cavities conduit pipe.Among Fig. 3, substantially, 650nm should be big to the ratio of 532nm than 650nm to the ratio of 580nm, and the reason why we select 650nm and 532nm wavelength is to have the low-power other semiconductor lasers of ready-made commercial product to use.

Embodiment 3: the design of light detection device

Fig. 4 realizes our purpose with the detecting system that above photoelectric subassembly of conclusion work is integrated.

Control circuit 420 among Fig. 4 is two groups of lasers of may command, with 650nm, 532nm is that example is done anti-phase mutually regulating type pulse output, just when 650nm laser light source 431 was opened, 532nm laser light source 441 just was closed condition (OFF State), and vice versa.These two groups of laser light are divided into twice optical path 450 and 460 via optical path 430, optical path 440 through behind the spectroscope 435.Light can enter optical fiber 451 through lens or suitable optical module 437 at optical path 450 and be led into tissue, and turning back to lens or suitable optical module 437, spectroscope 436 along original route after reflection reflexes to lens or suitable optical module 438 again.Delivering to light detection device 472 after lens or suitable optical module 438 are collected light makes prime and amplifies back repeated transmission to general amplifier 473 signal is done filtering and amplification.Afterwards, just deliver to control circuit 420 and do relevant signal processing, with 650 nm the ratio of 530 nm is presented on the signal display 410 at last.Simultaneously, also can establish an alert news threshold values on circuit, just when 650 nm surpassed 3 to the ratio of 532 nm, control circuit 420 just sent a kind of sound alert news; When this ratio is reduced to 2 down suddenly by 3, send another alert news again.The former is that the caution probe has reached ligamenta flava, and the latter warns probe and reached spinal epidural cavity.Send 650 nm or 532 nm light to the tissue simultaneously, also that it is a part of light mat reflecting mirror 461 of spectroscope 436 is directed at another light detection device 462 and amplifies signal, with the monitoring as light intensity.

The structure of Fig. 4 is different with Fig. 2, and reason is in pilot study(perspective study) in, our usefulness be thicker Y shape fibre bundle.But, can't resembling among the figure two, the fibre bundle that design is divided in the cavity that multi beam penetrates sub-pin at the sub-pin of the anesthesia of reality.Therefore, we will use (a) single plastic optical fiber, or (b) oversensitive glass optical fiber bundle, single bundle optical fiber do incident simultaneously and receive the media of reflection signal.So, the interface of relevant optical module must coating anti reflection film.

Fig. 5 is that another is selected, and just the number of fibers in sub-pin is greater than under one the situation, and we can allow the optical fiber of a part only bring the leaded light of making light source, and the optical fiber of another part is then brought the leaded light of organizing reflected light to enter light detection device.Its operation principle is similar to Fig. 4.

The main idea of the present invention is to utilize the difference of each organizational groups composition of organism, each tissue has the optical characteristics of different absorptions and reflection and fluorescence Raman to the light of different wave length, utilize the light source of several different-wavebands to be projeced in the biological tissue through optical fiber, differentiate optical properties of tissue and come the identification puncture needle in which kind of tissue or can reach specific location purpose accurately on the surface of biological tissue, organ, carry out specific treatment or operation again.

This technical scheme can be used specific light source irradiation tissue, and identification tissue oxygenation amount, or bioluminescence reach distinguishing of harmful structure, the effect that the diagnoses and treatment that progresses greatly is treated.

For example, be example with sticking the sticking of Wicresoft's abdominal operation midgut, the middle-aged women great majority all have the sticking glutinous phenomenon of intestinal, must beat an air-filled pore at abdominal part earlier before Minimally Invasive Surgery, allow abdominal part inflate, and convenient operation is carried out.Be stained with glutinous place if first hole of doctor is beaten at intestinal, this moment, intestines were damaged at once, and Minimally Invasive Surgery is promptly failed.Sufferer must be opened the large tracts of land wound at abdominal part, and this is not that the doctor expects at once.The doctor is stained with glutinous phenomenon in a organized way if with using the described technical scheme of present embodiment, with regard to this technology, just can find that immediately signal is unusual in the piercing process when first inflates the hole at cutter, has both exempted the risk of Minimally Invasive Surgery failure by changing punch position so.

Again for example, in the emergency and severe disease first aid, the doctor can not find sufferer table superficial part position blood vessel through regular meeting, uses the described technical scheme of present embodiment, so, and by observing the optical characteristics difference between blood vessel wall and the muscular tissue, the tram that can tell blood vessel fast.

Again for example, certain drug precisely is shipped to particular tissue surface or in-house application.Certain drug index target medicine, the gold nanoparticle ball, fluorescence medicament etc., use the described technical scheme of the embodiment of the invention, by with drug delivery to specific tumors, long-time growth of following the trail of the living animal interior tumor cell reaches the reaction to Drug therapy, even comes traget antibody, small-molecule drug to observe distribution and metabolism in animal body by fluorescence.

Be that real case is described in detail the present embodiment technical scheme with spinal dura mater anesthesia below:

Spinal dura mater anesthesia (epidural anesthesia) is injected local anesthetic in the spinal epidural cavity (epidural space), spinal nerves is done the reversibility blocking-up, to obtain the method for anaesthetic effect, be also referred to as spinal dura mater Interruption (epidural block), this is one of normal half body anesthesia of using of surgical operation.For the anesthesia doctor, when carrying out this anesthesia surgery, the problem of most critical is exactly the position that is accurately to differentiate spinal epidural cavity.At first with the viewpoint of anatomical physiology, as shown in Figure 1, spinal epidural cavity is a potential chamber between spinal dura mater (dural mater) and ligamenta flava (ligamentum flavum), be a very narrow cavity, the detecting when also therefore causing this anesthesia of execution and the degree of difficulty of location.This cavity has the different difference of width because of people's build is different with the age again, and is normal, and the wideest at waist center place, its width is 3 ~ 6mm, and only is 1 ~ 5mm at middle chest.If wear out dura mater accidentally, gently then can cause the headache of patient's postoperative (post-dural puncture headache, sequela such as PDPH), heavy then the danger of infringement spinal cord is arranged, the therefore importance that correctly punctures as can be known.

The present invention is described in detail, and tangible example is arranged, and any people who possesses basic skills in this field can both use it and do and variously substitute, modifies or improve, but clearly, these all can not separate with spirit of the present invention and invention scope.

Therefore, though should be appreciated that according to preferred embodiment and arbitrarily characteristics specifically disclose the present invention, know the content that this skill person still can revise and change wherein to be disclosed, suchlike modifications and variations are still in the present invention's claim.The above only is preferred embodiment of the present invention, and is in order to restriction the present invention, within the spirit and principles in the present invention not all, any modification of being done, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (6)

1. an injection cover group is characterized in that, comprising:

A middle aircraft carrier pin, individual tissue is used to puncture; And

Gap pin in the swapping type comprises an optical fiber at least in its center hole.

2. injection cover group according to claim 1 is characterized in that, the formula pin of substituting that wherein contains optical fiber is drawn out of when female pin arrives the particular organization position, and is replaced by an injection catheter.

3. injection cover group according to claim 1, it is characterized in that, described optical fiber is single fiber, multicore fiber bundle, Y shape optical fiber beam or a plurality of optical fiber, and the optical fiber group of wherein inserting gap pin in the swapping type can be a whole piece or is divided into several sections and is combined into an optical fiber group.

4. injection cover group according to claim 1 is characterized in that, also comprises:

One smooth detection device is used to detect individual optical properties of tissue; And

One light source provides aforementioned lights detection device required incident light source;

Wherein, described smooth detection device and light source are connected with optical fiber in the described sub-pin.

5. injection cover group according to claim 4 is characterized in that described light source can provide the light of two or more different wave lengths.

6. injection cover group according to claim 5 is characterized in that described light source is a laser light.

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