CN102920836A - Traditional Chinese medicine composite for treating immune thrombocytopenic purpura - Google Patents
Traditional Chinese medicine composite for treating immune thrombocytopenic purpura Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composite for treating immune thrombocytopenic purpura. The traditional Chinese medicine composite is prepared from the following raw materials in parts by weight: 10-30 parts of cornu bubali, 10-30 parts of indigo naturalis, 10-30 parts of lithospermum, 10-30 parts of pseudo-ginseng, 10-30 parts of selaginella tamariscina, 10-30 parts of angelica sinensis, 1-5 parts of ginseng, 10-30 parts of astragalus mongholicus, 10-30 parts of rehmannia root, 1-5 parts of antler slices, 10-30 parts of tortoise shell, 1-5 parts of placenta hominis, 10-15 parts of radix salviae miltiorrhizae, 10-30 parts of polygonum cuspidatum and 10-20 parts of cortex moutan. The traditional Chinese medicine composite is prepared into powder, pills, pastes or tablets by weighing the raw materials in the weight proportion and using a conventional traditional Chinese preparation method. The traditional Chinese medicine composite is high in components and is quantitatively blended; the dosage form can be powder, pills, pastes or tablets; and the medicines are matched with each other, the composite has the functions of replenishing qi to invigorate the spleen, governing the blood, tonifying kidney to perform spermatogenesis and culture the blood, promoting blood circulation to remove blood stasis to generate new blood, so that the human immunocompetence can be obviously improved, the micro-circulation is improved, the blood cells are increased, and the worries and the poor reaction of the patients caused by hormonotherapy of western medicine and spleen cutting are improved.
Description
Technical field
The present invention relates to Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of immunologic thrombocytopenic purpura.
Background technology
Purpura is more common clinically sign, often causes because platelet counts reduces, therefore the general term thrombocytopenic purpura.Wherein common with immunologic thrombocytopenic purpura, though the thrombotic thrombocytopenic purpura sickness rate is lower, mortality rate is higher.Idiopathic thrombocytopenic purpura is considered to agnogenic hemorrhage in the past always, and large quantity research has in recent years confirmed that primary disease is relevant with immunoreation, therefore should be called idiopathic thrombocytopenic purpura (also being called for short ITP).The Hematologic Features of primary disease is thrombocytopenia in the peripheral blood, and platelet surface is combined with antiplatelet antibody, and platelet life span shortens, but the bone marrow megakaryocyte compensatory increases and the thrombocytopoiesis obstacle.
In the prior art, the method for the treatment of immunologic thrombocytopenic purpura is a lot.Wherein, modal method is hormonotherapy and the Splenectomy for treating method of Western medicine, but all has side effect, the trouble and worry that can bring or untoward reaction.Therefore, the Study of Traditional Chinese Medicine prescription becomes those skilled in the art's important selection.
Summary of the invention
For the prior art above shortcomings, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of immunologic thrombocytopenic purpura, with the hormonotherapy of improving Western medicine with cut spleen to trouble and worry and untoward reaction that the patient brings, solve the slow defective of other Chinese Herbs.
Realize above-mentioned purpose, the present invention adopts following technical scheme: a kind of Chinese medicine composition for the treatment of immunologic thrombocytopenic purpura, and it is to be made by the following portions by weight proportioning raw materials:
Cornu Bubali 10-30 part; Indigo Naturalis 10-30 part; Radix Arnebiae (Radix Lithospermi) 10-30 part; Radix Notoginseng 10-30 part; Roll up white 10-30 part; Radix Angelicae Sinensis 10-30 part; Radix Ginseng 1-5 part; Radix Astragali 10-30 part; Radix Rehmanniae 10-30 part; Cornu Cervi tablet 1-5 part; Carapax Et Plastrum Testudinis 10-30 part; Placenta Hominis 1-5 part; Radix Salviae Miltiorrhizae 10-15 part; Rhizoma Polygoni Cuspidati 10-30 part; Cortex Moutan 10-20 part;
The preparation method of described Chinese medicine composition takes by weighing raw material by above-mentioned weight proportion, makes powder, pill, cream system, tablet with the conventional preparation method of Chinese medicine.
Compared to existing technology, the present invention has following beneficial effect:
Treatment by Chinese herbs ITP determined curative effect of the present invention, safety, few side effects; And prescription is superior, from thousands of kinds of Chinese medicines the screening and go out ten five tastes, quantitatively be mixed, dosage form is powder, pill, unguentum, tablet.Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis invigorating the spleen and replenishing QI nourish blood, take the photograph blood in the compositions; Cornu Cervi tablet, Placenta Hominis, the strong marrow of Carapax Et Plastrum Testudinis Zishen fill fine, with activated bone marrow hemopoietic, the stable platelet that promotes; The Radix Rehmanniae, Cortex Moutan, Carapax Et Plastrum Testudinis, Cornu Bubali, Rhizoma Polygoni Cuspidati, Indigo Naturalis replenishing YIN and removing heat removing pathogenic heat from blood and toxic substance from the body are to control the absurd row of its inclined to one side YinXuXueRe, the card that the blood oozing from the body openings or subcuta neous tissue arteries and veins is outer; Radix Salviae Miltiorrhizae, Radix Notoginseng, the white promoting blood flow and remove blood stasis and stop bleeding of volume, and do not hinder fresh blood.
All medicines share, and have replenishing QI to invigorate the spleen, system blood, and kidney-tonifying sperm-generating nourishes blood, and the blood circulation promoting and blood stasis dispelling tissue regeneration promoting is taken the photograph the merit of blood.Can significantly improve the human body immunity, improve microcirculation, promote platelet, improve the hormonotherapy of Western medicine and cut trouble and worry and the untoward reaction that spleen brings to the patient.
By to the hundreds of routine clinical observation on the therapeutic effect of immunologic thrombocytopenic purpura, effective percentage reaches 92%, and inefficiency is 8%.The present invention has instant effect, and relapse rate is low, and medical expense is few, the long-term taking advantage such as also have no adverse reaction.Simultaneously, chronic aplastic anemia anemia, leukopenia also there is preferably therapeutic effect.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further detail.
Concrete prescription sees table:
| Prescription | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| Cornu Bubali | 10 | 10 | 15 | 30 | 20 |
| Indigo Naturalis | 10 | 10 | 10 | 30 | 15 |
| Radix Arnebiae (Radix Lithospermi) | 10 | 10 | 15 | 30 | 20 |
| Radix Notoginseng | 10 | 10 | 10 | 18 | 30 |
| Volume is white | 10 | 10 | 15 | 18 | 30 |
| Radix Angelicae Sinensis | 30 | 30 | 30 | 20 | 30 |
| Radix Ginseng | 5 | 5 | 5 | 1 | 3 |
| The Radix Astragali | 30 | 30 | 30 | 10 | 25 |
| The Radix Rehmanniae | 15 | 20 | 20 | 30 | 20 |
| Cornu Cervi tablet | 5 | 5 | 5 | 1 | 3 |
| Carapax Et Plastrum Testudinis | 10 | 10 | 10 | 30 | 18 |
| Placenta Hominis | 5 | 5 | 5 | 1 | 3 |
| Radix Salviae Miltiorrhizae | 10 | 10 | 10 | 15 | 12 |
| Rhizoma Polygoni Cuspidati | 10 | 10 | 15 | 30 | 15 |
| Cortex Moutan | 10 | 10 | 10 | 20 | 15 |
Two, the making of Chinese medicine composition can be chosen one of following method wantonly:
1, by above-mentioned part by weight proportioning, makes pill.
2, by above-mentioned part by weight proportioning, make unguentum.
Three, proven case:
1, Chen, woman, 35 years old.First visit on July 1 in 2008.The patient occurred through the row first quarter moon unclean before 1 year, gynaecological examination is normal, and is light red through color, and amount is many, dizziness, tinnitus, weak, two skin of lower extremity ecchymosis.Be diagnosed as idiopathic thrombocytopenic purpura in certain county people's hospital.The platelet 15 * 10 of having a blood test
9/ L, after usefulness XUEKANG KOUFUYE prednisone was treated February, the dermal ecchymosis went down, and 5 Japanese sides are clean through row, dizzy, weak alleviating.The platelet 102 * 10 of having a blood test
9/ L rises to normally.The oral gradually decrement of prednisone, when taking to 10mg on the 1st, skin is observed again new ecchymosis, and menstrual phase extends to 12 only.The platelet 25 * 10 of having a blood test
9/ L.Dizzy weak the increasing the weight of of patient, lack of appetite, timid cold, the nocturia frequency, shallow complexion is slept poor.To Chongqing large hospital diagnosis and treatment, the routine of having a blood test: WBC7.6 * 10
9/ L, Hb132g/L; PLT21 * 10
9/ L, bone marrow aspiration are diagnosed as " idiopathic thrombocytopenic purpura ", and the blood coagulation spectrum is normal, and cardiopulmonary are normal, and the liver spleen is little.Give hormone, add immunosuppressant treatment.Hormone side effect is too large but the patient worries, and last time hormone therapy is unsuccessfully refused medication in addition, is illustrated in the here tcm diagnosis and treatment by the people.Card is seen: patient's shallow complexion, and lassitude, dizzy weak, tinnitus, the cold of fear of cold limb, nocturia is frequent, lack of appetite, xerostomia is tasteless, the skin of lower extremity ecchymosis, thin white fur of tongue, pale tongue, thready pulse is number slightly.Tcm diagnosis: blood disorder (flesh [blood is ugly] L ü).Card belongs to spleen kidney two and loses asthenia of essence and blood, QI failing to control blood.Prescription: ginseng sees the above table embodiment 1; Be mixed with pill by above-mentioned part by weight, take 20 days after, the patient cables it: dizzy weak alleviating, the skin of lower extremity ecchymosis reduces.Advise it to continue and take 15 days, the examination platelet.Further consultation on August 5 in 2008: the patient has rosy cheeks, and spirit is rather good, and dizziness is weak obviously to alleviate, and skin of lower extremity stasis of blood class disappears substantially, the platelet 88 * 10 of having a blood test
9/ L, effect is remarkable, continues to take to chase after January and controls.JIUYUE was examined on the 10th in 2008, and all diseases of patient disappear, and strong such as ordinary person, the platelet of having a blood test shows: PLT113 * 10
9/ L recovers normal, and the patient required after treatment 2 months.After 2 years, former patient is with friend to come here to diagnose a disease, and the platelet of announcement keeps normal, again without other discomfort always after treatment by Chinese herbs last time.
2, Zhang, woman, 5 years old, first visit on July 1 in 2010.Infant is because of thrombocytopenic purpura in May, 1.Recently, aggravation is moved in the Chongqing large hospital.The routine of having a blood test is shown: WBC9.52 * 10
9/ L, N:0.10, L:0.84; RBC:3.59 * 10
12/ L, Hb99g/L; PLT30 * 10
9/ L.Bone marrow smear: meet thrombocytopenic purpura (ITP).Diagnosis: chronic thombocytopenic purpura, granulocytopenia? give prednisone 5mg, 2 times on the 1st, in conjunction with symptomatic treatment.The routine of having a blood test after 1 week is shown: WBC10.6 * 10
9/ L, N:0.05, L:0.75; Hb100g/L; PLT102 * 10
9/ L, infant body temperature, breathing, heart rate are normal, the liver spleen is little, and two skin of lower extremity are dispersed in the old ecchymosis.Leave hospital and continue to take prednisone 5mg/ time, a twice-daily, D-Cal 0.3g/ time, a twice-daily.The infant state of an illness occurs again repeatedly after two weeks, and new petechia appears in two skin of lower extremity, lassitude, and dizzy weak, the decreased food intake of receiving is few.Move in certain large hospital, the routine of having a blood test is shown: WBC7.10 * 10
9/ L, N:0.47, L:0.41; RBC:4.2 * 10
12/ L, Hb89g/L; PLT21 * 10
9/ L gives the symptomatic treatments such as platelet transfusion.Parents of hospitalized children is worried very much, noses about everywhere this sick method for the treatment of.Introduce here to require the Chinese medicine diagnosis and treatment by friend.Examine and see: the infant hair is sparse, and shallow complexion is omited edema, pale lips, and lassitude is off one's feed, and lazy speech happiness is sleeping, and yellow urine is hard and dry, thin white fur of tongue, pale tongue, deep-thready pulse.Tcm diagnosis: blood disorder (flesh blood is ugly).Ginseng sees the above table embodiment 2, is mixed with unguentum by above-mentioned part by weight and takes.After taking 30 days, infant comes further consultation, and the routine of having a blood test is shown: WBC6.5 * 10
9/ L, RBC:4.3 * 10
12/ L, Hb125g/L; PLT68 * 10
9/ L (platelet).Spirit is better, has rosy cheeks, and head has grown soft of many black, and the lower limb ecchymosis begins to disappear, food can, two is just normal.Parents with Children is the automatic stop hormone, still requires treatment by Chinese herbs, and continuing takes 2 months.15 days three October in 2010 examined, and the platelet of having a blood test shows: PLT125 * 10
9/ L recovers normal, and infant is again without other discomfort, and new ecchymosis does not appear in two skin of lower extremity yet.It can consider drug withdrawal, but Parents with Children is feared its recurrence, still requires to cure 3 months.After 1 year, infant goes home to celebrate a festival with its father and mother, and the spy comes here to visit, and this disease of announcement heals, and daughter prepares to go to school.
3, Liu: woman, 36 years old, first visit on May 24 in 2004.The patient went out to celebrate a festival on March 8th, 2002, suddenly dizziness, cardiopalmus, fall in ground, unconscious, repeatedly exhale sum to pinch its family members afterwards and press among the people, wake up as usual afterwards, do not draw attention and treat.The patient was recurred again and was fainted on August 2nd, 2004, and weak after waking up, lack of appetite is breathed hard, and cardiopalmus is moved in certain county people's hospital, is diagnosed as thrombocytopenia.Its routine blood test shows: WBC4.5 * 10
9/ L, RBC:3.25 * 10
12/ L, Hb90g/L; PLT21 * 10
9/ L
The liver spleen is little, doubts the blood spectrum normal, and cardiopulmonary are normal, give XUEKANG KOUFUYE, and compound recipe soap tablet, the symptomatic treatments such as platelet transfusion be after January, the platelet of having a blood test: PLT85 * 10
9/ L, Hb125g/L; WBC4.7 * 10
9/ L, symptom takes a turn for the better and leaves hospital.Since economic conditions, the not continuous medicine of using of patient.On October 2nd, 2004, the patient faints suddenly in being on duty on the way, and is unconscious, after the colleague is sent to hospital emergency, changes Chengdu front three hospital treatment over to.When being admitted to hospital, the routine of having a blood test is shown: WBC4.7 * 10
9/ L, RBC:3.6 * 10
12/ L, Hb85g/L; PLT18 * 10
9/ L, the liver spleen is little, and the blood coagulation spectrum is normal.Bone marrow aspiration diagnosis: idiopathic thrombocytopenic purpura.Give platelet transfusion, human γ-globulin, the symptomatic treatments such as oral meticorten, after 20 days, platelet is always in 15-22 * 10
9/ L fluctuation, the patient is weak, cardiopalmus, lack of appetite, skin of lower extremity ecchymosis.Main examine the doctor and require the patient to perform to cut spleen operation mental preparation, but patient and family members thereof disagree with and cut spleen and initiatively leave hospital.On December 5th, 2004, come upon somebody's introduction here to require to use Chinese medicine.Card is seen: patient's lassitude, shallow complexion, lip is light without the pool, lack of appetite, xerostomia, drink cold, large constipation, the menstruation first quarter moon is unclean, two skin of lower extremity ecchymosis present, thin white fur of tongue, thready pulse summary number.Tcm diagnosis: blood disorder, card belongs to deficiency of both QI and YIN, asthenia of essence and blood, bleeding due to blood-heat.Ginseng sees the above table embodiment 3, is mixed with pill by above-mentioned mass ratio, takes 30 days.Further consultation on January 10 in 2005, the platelet 75 * 10 of having a blood test
9/ L, all proofs are aobvious to be alleviated, and advises it to continue and takes 2 months, notes not flu, prohibits raw food, distantly related thing.25 days three March in 2005 examined, the platelet 210 * 10 of having a blood test
9/ L, strong such as ordinary person, the consideration drug withdrawal, but the patient still requires to chase after and controls 3 months to consolidate it.In May, 2007, former patient lends the poor here of just coming, the over the past two years repeatedly check of announcements, and platelet keeps normally always, and this disease recurs again.
5 pairs of thrombocytopenia of embodiment 4 and embodiment all have obvious curative effects.
Need to prove at last, above embodiment is only in order to illustrate technical scheme of the present invention but not the restriction technologies scheme, although the applicant has been described in detail the present invention with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, those are made amendment to technical scheme of the present invention or are equal to replacement, and do not break away from aim and the scope of the technical program, all should be encompassed in the middle of the claim scope of the present invention.
Claims (3)
1. a Chinese medicine composition for the treatment of immunologic thrombocytopenic purpura is characterized in that, it is to be made by the following portions by weight proportioning raw materials:
Cornu Bubali 10-30 part; Indigo Naturalis 10-30 part; Radix Arnebiae (Radix Lithospermi) 10-30 part;
Radix Notoginseng 10-30 part; Roll up white 10-30 part; Radix Angelicae Sinensis 10-30 part;
Radix Ginseng 1-5 part; Radix Astragali 10-30 part; Radix Rehmanniae 10-30 part;
Cornu Cervi tablet 1-5 part; Carapax Et Plastrum Testudinis 10-30 part; Placenta Hominis 1-5 part;
Radix Salviae Miltiorrhizae 10-15 part; Rhizoma Polygoni Cuspidati 10-30 part; Cortex Moutan 10-20 part.
2. the Chinese medicine composition of described treatment immunologic thrombocytopenic purpura according to claim 1, described raw material weight umber proportioning is: 5 parts of Radix Ginsengs, 30 parts of the Radixs Astragali, 15 parts in the Radix Rehmanniae, 5 parts of Cornu Cervi tablets, 10 parts of Carapax Et Plastrum Testudiniss, 5 parts of Placenta Hominiss, 10 parts of Indigo Naturaliss, 10 parts of Cornu Bubalis, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Polygoni Cuspidati, 10 parts of Cortex Moutans, 30 parts of Radix Angelicae Sinensis, white 10 parts of volume, 10 parts of Radix Notoginseng, 10 parts of Radix Arnebiae (Radix Lithospermi)s.
3. a preparation method for the treatment of the Chinese medicine composition of immunologic thrombocytopenic purpura takes by weighing raw material by above-mentioned weight proportion, makes powder, pill, cream system or tablet with the conventional preparation method of Chinese medicine.
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Cited By (3)
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| CN103720916A (en) * | 2014-01-17 | 2014-04-16 | 张桂清 | Tea extract for relieving thrombocytopenic purpura caused by radiation and preparation method thereof |
| CN105963392A (en) * | 2016-07-04 | 2016-09-28 | 上海世道健康科技有限公司 | Traditional Chinese medicine composition, preparation and preparation method and purpose thereof |
| CN108186809A (en) * | 2018-02-06 | 2018-06-22 | 丁樱 | A kind of clearing away heat to stop bleeding particle and preparation method thereof |
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| CN108186809A (en) * | 2018-02-06 | 2018-06-22 | 丁樱 | A kind of clearing away heat to stop bleeding particle and preparation method thereof |
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| CN102920836B (en) | 2014-05-07 |
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