CN102920824A - Liniment for treating bedsore and preparation method thereof - Google Patents

Abstract

The invention relates to liniment for treating bedsore, which is prepared by using Chinese and Western medicaments as raw material drugs. The liniment is prepared by a method comprising the following steps: grinding selected golden thread, golden cypress, common cephalanoplos herb, tribulusterrestris and lightyellow sophora root into powder of 100-120 meshes; immersing for one week with purified water; filtering to obtain filtrate 1; adding 10g of chloramphenicol into the filtrate 1; and sterilizing and disinfecting to obtain the liniment product. The liniment consisting of Chinese and Western medicaments has the functions of inhibiting bacteria and sterilizing, and promoting blood circulation to remove stasis, and can achieve the bedsore treatment aims of quick response and no relapse.

Description

A kind of liniment for the treatment of decubital ulcer and preparation method thereof

Technical field

The present invention relates to a kind of liniment that is used for the treatment of decubital ulcer, particularly relate to a kind of liniment of the treatment decubital ulcer for preparing take Chinese medicine and western medicine as crude drug.The invention still further relates to the preparation method of this liniment.

Background technology

Decubital ulcer (claiming again pressure ulcer, pressure ulcer) is because the long-term pressurized of local organization, continuous ischemia, anoxia, malnutrition occur and causes tissue fester's necrosis.Decubital ulcer is a kind of clinical common complication, and disease is rapid, very easily recurrence after the healing, and severe patient may cause various fatal diseases, has become one of the most serious complication of bed patient.

Clinical minute three phases of decubital ulcer, erythema device, blister phase and ulcerative stage, the state of an illness increases the weight of step by step, and more Therapeutic Method adopts the disinfection medicine to cooperate wound surface to recover medicine and treats, but existing medication effect is general, very easily recurrence after the treatment.

Summary of the invention

The purpose of this invention is to provide a kind of liniment that is used for the treatment of decubital ulcer, this medicine forms the effect with antibacterial sterilization, blood circulation promoting and blood stasis dispelling by Chinese medicine and western medicine, can play instant effect, repeatedly purpose not to the treatment of decubital ulcer.

Simultaneously, another object of the present invention provides the preparation method of liniment of the present invention.

Medicine of the present invention is that the medicine by following parts by weight is that crude drug prepares:

Rhizoma Coptidis 1～5 Cortex Phellodendri 2～7 Herba Cirsiis 2～8

Fructus Atriplicis Sibiricae 4～9 Radix Sophorae Flavescentiss 2～8 chloromycetin 1～7.

Preferably, medicine of the present invention is that the medicine by following parts by weight is that crude drug prepares:

Rhizoma Coptidis 2～4 Cortex Phellodendris 4～5 Herba Cirsiis 4～6

Fructus Atriplicis Sibiricae 5～7 Radix Sophorae Flavescentiss 4～6 chloromycetin 2～4.

The traditional Chinese medical science thinks that decubital ulcer is many because of deficient qi and blood, and qi depression to blood stasis causes, the prolonged illness bed, and pressurized position stagnation of QI-blood, blood vessels are obstructed, the meridians obstruct, deficiency of both QI and blood is invaded in the malicious heresy, and the mistake of muscle muscles and bones is supported the rotten one-tenth skin ulcer of then bursting, and touching difficulty is more.The Therapeutic Principle should be sterilization sterilization, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing.The Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication; The Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication; Herba Cirsii removing blood stasis to reduce swelling, antibacterial; Fructus Atriplicis Sibiricae circulation of qi promoting removing blood stasis; The Radix Sophorae Flavescentis heat clearing away is except dry, antibacterial; The chloromycetin bacteriostasis and sterilization.All medicines share, heat-clearing and toxic substances removing, and blood circulation promoting and blood stasis dispelling, bacteriostasis and sterilization is used for the treatment of decubital ulcer, has instant effect, repeatedly characteristics not.

The preparation method of liniment of the present invention comprises the following steps:

1) get 1～5 part of Rhizoma Coptidis, 2～7 parts of Cortex Phellodendris, 2～8 parts of Herba Cirsiis, 4～9 parts of Fructus Atriplicis Sibiricaees, 2～8 parts of Radix Sophorae Flavescentiss, be ground into 100-120 order powder, add in 40～60 parts of pure water and to soak a week, filter and obtain filtrate 1;

2) add 1～7 part in chloromycetin in filtrate 1, the sterilization virus killing makes liniment.

Preferably, the preparation method of liniment of the present invention comprises the following steps:

1) get 2～4 parts of Rhizoma Coptidis, 4～5 parts of Cortex Phellodendris, 4～6 parts of Herba Cirsiis, 5～7 parts of Fructus Atriplicis Sibiricaees, 4～6 parts of Radix Sophorae Flavescentiss, be ground into 100-120 order powder, add in 40～60 parts of pure water and to soak a week, filter and obtain filtrate 1;

2) add 2～4 parts in chloromycetin in filtrate 1, the sterilization virus killing makes liniment product.

Above-mentioned liniment can further be processed into the exterior-applied formulations such as liniment, unguentum according to conventional method, the preferred dosage form of the present invention is liniment.

For further investigating clinical efficacy and the safety of medicine of the present invention, select 69 routine patients with bedsore that the curative effect of medicine of the present invention has been carried out clinical observation.All cases all according to the diagnostic criteria of " disease of tcm Standardization of diagnosis and curative effect ", is diagnosed as decubital ulcer.

Therapeutic Method

Adopt the liniment of medicine of the present invention to treat, every day 3 times, smear the affected part.7 days is a course for the treatment of, uses altogether 2 courses for the treatment of.

Criterion of therapeutical effect

According to the criterion of therapeutical effect of " disease of tcm Standardization of diagnosis and curative effect ", cure: the brown erythema disappears, or the wound healing that festers; Take a turn for the better: erythema does not disappear entirely, or the skin ulcer face slough that festers comes off, granulation, and the skin ulcer face dwindles gradually; Do not heal: the open sore part increases, and it is more than to fester.

Efficacy result sees Table 1 after all cases treatment.

Curative effect after the treatment of table 1 all cases

Group	The example number	Cure n(%)	Improvement n(%)	N(% more)	Total effective rate n(%)
						All cases	69	40（58）	27（39）	2（3）	67（97）

Concrete case

Liu so-and-so, the man, 83 years old, be unable to leave the bed all to fester to decubital ulcer 4 years to two buttocks because of encephalopathy before 7 years, bring into use external used medicine of the present invention in February, 2012 after recovery from illness in 7 days, so far recurrence.

Feng so-and-so, the man, 79 years old, 3 years causes were suffered from encephalopathys and general paralysis, formed decubital ulcer to the both sides buttocks, brought into use external used medicine of the present invention on October 8th, 2011, medication recovery from illness in 5 days, so far recurrence.

Feng so-and-so, the woman 76 years old, because of encephalopathy bed 4 years, brings into use external used medicine of the present invention, medication afterwards recovery from illness in 9 days, so far recurrence on August 8th, 2011.

Lee so-and-so, the woman, 78 years old, because of suffer from hypertension to general paralysis for 6 years, bring into use external used medicine of the present invention on April 8th, 2012, medication afterwards recovery from illness in 9 days, so far recurrence.

Willow so-and-so, the man, 81 years old, suffer from the encephalopathy panplegia, two buttocks festered and had a surplus in 4 years, brought into use external used medicine of the present invention on August 3rd, 2012, medication afterwards recovery from illness in 7 days, so far recurrence.

The specific embodiment

Embodiment 1

Get selected Rhizoma Coptidis 10g, Cortex Phellodendri 20g, Herba Cirsii 40g, Fructus Atriplicis Sibiricae 50g, Radix Sophorae Flavescentis 40g, be ground into 100-120 order powder, add in the 400g pure water and soak a week, filter and obtain filtrate 1;

Add chloromycetin 10g again in filtrate 1, the sterilization virus killing makes liniment product.

Embodiment 2

Get selected Rhizoma Coptidis 50g, Cortex Phellodendri 70 g, Herba Cirsii 60 g, Fructus Atriplicis Sibiricae 70g, Radix Sophorae Flavescentis 60g, be ground into 100-120 order powder, add in the 600g pure water and soak a week, filter and obtain filtrate 1;

Add chloromycetin 70g again in filtrate 1, the sterilization virus killing makes liniment product.

Embodiment 3

Get selected Rhizoma Coptidis 30g, Cortex Phellodendri 50 g, Herba Cirsii 50 g, Fructus Atriplicis Sibiricae 60g, Radix Sophorae Flavescentis 50g, be ground into 100-120 order powder, add in the 500g pure water and soak a week, filter and obtain filtrate 1;

Add chloromycetin 30g again in filtrate 1, the sterilization virus killing makes liniment product.

Claims (4)

1. liniment for the treatment of decubital ulcer is that the medicine by following portions by weight is crude drug, prepares:

Rhizoma Coptidis 1～5 Cortex Phellodendri 2～7 Herba Cirsiis 2～8

Fructus Atriplicis Sibiricae 4～9 Radix Sophorae Flavescentiss 2～8 chloromycetin 1～7.

2. the preparation method of the liniment of the described treatment decubital ulcer of claim 1 may further comprise the steps:

1) get 1～5 part of Rhizoma Coptidis, 2～7 parts of Cortex Phellodendris, 2～8 parts of Herba Cirsiis, 4～9 parts of Fructus Atriplicis Sibiricaees, 2～8 parts of Radix Sophorae Flavescentiss, be ground into 100-120 order powder, add in 40～60 parts of pure water and to soak a week, filter and obtain filtrate 1;

2) add 1～7 part in chloromycetin in filtrate 1, the sterilization virus killing makes liniment product.

3. the liniment for the treatment of decubital ulcer according to claim 1 is that the medicine by following portions by weight is crude drug, prepares:

Rhizoma Coptidis 2～4 Cortex Phellodendris 4～5 Herba Cirsiis 4～6

Fructus Atriplicis Sibiricae 5～7 Radix Sophorae Flavescentiss 4～6 chloromycetin 2～4.

4. the preparation method of the liniment for the treatment of decubital ulcer claimed in claim 3 may further comprise the steps:

1) get 2～4 parts of Rhizoma Coptidis, 4～5 parts of Cortex Phellodendris, 4～6 parts of Herba Cirsiis, 5～7 parts of Fructus Atriplicis Sibiricaees, 4～6 parts of Radix Sophorae Flavescentiss, be ground into 100-120 order powder, add in 40～60 parts of pure water and to soak a week, filter and obtain filtrate 1;

2) add 2～4 parts in chloromycetin in filtrate 1, the sterilization virus killing makes liniment product.