CN102895472A - Topical combination medicament for treating dental ulcer and preparation method thereof - Google Patents

Topical combination medicament for treating dental ulcer and preparation method thereof Download PDF

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CN102895472A
CN102895472A CN2012103682342A CN201210368234A CN102895472A CN 102895472 A CN102895472 A CN 102895472A CN 2012103682342 A CN2012103682342 A CN 2012103682342A CN 201210368234 A CN201210368234 A CN 201210368234A CN 102895472 A CN102895472 A CN 102895472A
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ulcer
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CN102895472B (en
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史培德
史弘千
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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a topical combination medicament for treating dental ulcer and a preparation method thereof. The medicament is prepared from the following raw materials in parts by weight: 14-20 parts of pearl, 2-5 parts of calculus bovis, 5-10 parts of borneol, 10-15 parts of indigo naturalis, 15-20 parts of dried alum, 10-15 parts of borax, 5-10 parts of daemonorops draco, 5-10 parts of cinnabar and 100-200 parts of sesame oil. According to the invention, the formulating prescription compatibility is appropriate and rigorous; the preparation method is unique; the adopted raw materials are Chinese herbal medicine, have no side effect, and do not bring with sequelae; moreover, the topical combination medicament for treating dental ulcer takes effect rapidly, is short in treatment course, is high in treatment rate, and is low in expense, and has unique treatment efficacy for repeated paroxysmal aphtha, root mucosa ulcer, buccal mucosa ulcer, lip mucosa ulcer and lingual mucosa ulcer.

Description

A kind of externally applied compound medicinal for the treatment of oral ulcer and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of externally applied compound medicinal for the treatment of oral ulcer
And preparation method thereof.
Background technology
Oral ulcer is called again " aphtha ", is the superficial ulcer that occurs on the oral mucosa, and large big or small from the grain of rice to Semen Glycines, the circular or oval of I, ulcer surface are recessed, congested on every side.Ulcer has the characteristics such as periodicity, recurrent and self limiting, is apt to occur in lip, cheek, lingual margin etc.The cause of disease and mechanism of causing a disease are still indefinite.Inducement may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in its generation, development.Treatment is mainly take topical therapeutic as main, and severe patient needs whole body therapeutic.Modern medicine thinks that primary disease is how relevant with factors such as psychentonia, endocrine disturbance, malnutrition, infection, heredity, immunologic dysfunction, digestive system disease.The traditional Chinese medical science is thought the generation of primary disease, and exopathogenic factor is take pyretic toxicity as main; Endogenous cause of ill mostly is feelings will internal injury, due to the eating and drinking without temperance, chamber overstrain.
Adopt of the treatment of primary disease taken the vitamin drug treatment more both at home and abroad at present, its effect can not be satisfactory, cures the symptoms, not the disease, and treatment cycle is long, occurred the Chinese patent medicine for the treatment of primary disease on the market, and effect is not ideal.
Summary of the invention
The purpose of this invention is to provide a kind of medicine of imitating fast, short treating period, treatment oral ulcer that cure rate is high.
For realizing purpose of the present invention, existing according to following technical scheme.This medicine is made by the raw material of following weight portion proportioning:
14-20 parts of Margaritas, 2-5 parts of Calculus Boviss, 5-10 parts of Borneolum Syntheticums, 10-15 parts of Indigo Naturaliss, 15-20 parts of dried Alumens, 10-15 parts of Boraxs, 5-10 parts of Sanguis Draxonis, 5-10 parts in Cinnabaris, 100-200 parts of Oleum sesami.
The fill a prescription weight proportion of best each raw material of the present invention is:
17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums, 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs, 7 parts of Sanguis Draxonis, 7 parts in Cinnabaris, 150 parts of Oleum sesami.
Preparation method of the present invention is: take by weighing respectively above-mentioned each medicine by prescription, then grind respectively, with Oleum sesami mix homogeneously furnishing pasty state, be.
Medicine of the present invention is according to the theory of Chinese medical discrimination, and is many because of long-pending on the heart-fire in conjunction with primary disease, and spleen-heat is wet contains, and hyperactivity of fire caused by deficiency of YIN, fumigation are in mouth, and intenseness of heat meat is rotten, due to the immunologic hypofunction.Therefore treating primary disease should heat-clearing and toxic substances removing, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, hemostasia and promoting granulation, just can receive treating both the principal and secondary aspects of a disease, be difficult for the radical cure effect of recurrence.
The side separates:
Margarita: tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula makes eye bright, removing toxic substances and promoting granulation.Control palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, the sore throat aphtha, order is given birth to cataracta, and skin infection does not close up for a long time.
Calculus Bovis: clear away heart-fire, eliminating phlegm is had one's ideas straightened out, cool liver, endogenous wind stopping, detoxifcation.Be used for the calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
Borneolum Syntheticum: logical all keys, loose stagnated fire, removing nebula makes eye bright, reducing swelling and alleviating pain.Control the apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha.
Indigo Naturalis: nature and flavor are salty-cold, heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion.Cure mainly: the epidemic febrile disease intenseness of heat, macule is spitted blood, is spat blood, the pharyngalgia aphtha, pediatric epilepsy scared, skin ulcer is swollen, erysipelas, snake bite and insect sting.
Dried Alumen: expectorant, dampness, antidiarrheal, hemostasis, detoxifcation, parasite killing.Control dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.
Borax: sweet, salty, cold.The external heat-clearing and toxic substances removing, detumescence, anticorrosion; Removing heat from the lung and dissipating phlegm for oral administration.Be used for acute tonsillitis, pharyngolaryngitis, laryngopharynx swelling and pain, aphtha of the mouth and tongue, stomatitis, gingivitis, otitis media.
Sanguis Draxonis: have promoting blood circulation to remove blood stasis, analgesic therapy, the effect of hemostasia and promoting granulation.Control continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.
Cinnabaris: it is relieving convulsion to clear away heart-fire, and the detoxifcation of calming the nerves is used for palpitation and being susceptible to fright, insomnia and dreamful sleep, and epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.
Oleum sesami: lower three warmers pyretic toxicity, logical intestine and small intestine, too fat to move, the granulation promoting of the disappearing pain relieving of putting on flesh.
Using method of the present invention is: an amount of directly the applying of medicine of the present invention smeared and affected part.Administration every day 2 to 3 times, patients with mild can be cured in general 12 hours, can cure in the general 2-7 of severe patient days.
The present invention be the inventor on the basis of secret prescription handed down in the family from generation to generation, in conjunction with oneself for many years summary of clinical experience, get through repeatedly testing, so this medicine for external use has unique curative effect to obstinate oral ulcer.It adopts multiple Chinese herbal medicine synergy, and comprehensive measure makes the active ingredient rapid permeability focus of medicine, eliminates patient part pain, promotes the ulcer spot healing.Its prescription compatibility is proper, rigorous, and preparation method is unique, adopts and is Chinese herbal medicine, and is without any side effects, do not stay sequela, and instant effect, short treating period, cure rate is high, expense is little.Repeated relapsing aphtha, root of the tooth mucosal ulcer, buccal mucosa ulcer, Mucosa of lip ulcer, periglottis ulcer there is unique curative effect.
Be the therapeutic effect of surperficial medicine of the present invention to oral ulcer, the inventor has carried out system's clinical observation to 298 routine intractable oral cavity ulcers, and its curative effect statistical result is as follows:
Contrast before and after table 1 dental ulcer treatment
Figure DEST_PATH_IMAGE001
Wherein, intractable oral cavity ulcer age of onset reckling 3 years old, the maximum 70 years old, male's 116 examples, women's 182 examples.
Show that from above-mentioned clinical statistics data the present invention alleviates patient's symptom and complication successful to the control state of an illness.
The specific embodiment:
Take by weighing following medicine by prescription:
17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums, 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs, 7 parts of Sanguis Draxonis, 7 parts in Cinnabaris, 150 parts of Oleum sesami.
Preparation method of the present invention is: take by weighing respectively above-mentioned each medicine by prescription, then grind respectively, evenly mix with Oleum sesami, be.
Model case:
Case 1, Liu, the man, 30 years old, the Shangqiu City people suffered from acute stomatitis, upper lower lip ulcer, also there are two place's ulcer in the Sublingual, babble at that time, tongue can not extending port outside.Go hospitalize not feel any better, the difficulty of not only having a meal, the also difficulty of speaking was used external used medicine of the present invention 2 days upon somebody's introduction, and ulcer disappears, recovery from illness.
Case 2, Wang, the man, 20 years old, Yong Cheng people from city, upper lip is taken back, and ulcer appears in side and appearance is hardened.Introduce through me, once lip was bitten in the past, bad during later fashion, fail to heal fully always, increased the weight of in nearly one month, what occur festering and touching hardens, and pain is obvious, and color is blackening gradually.I am afraid of to cancerate, and come that I go out medically, and the application of the invention external used medicine affected part every day administration 5 times used for 2 weeks continuously, ulcer, scleroma transference cure.
Case 3, Mrs Liu, 55 years old, the retired cadre suffered from periglottis ulcer, and ulcer appears in the tip of the tongue position, once uses antibiotic therapy after one week, body part ulcer occurs again, hurt like hell, the difficulty of speaking, take food, the application of the invention external used medicine 3 days, recovery from illness.
Case 4, Li Dan, the woman, 3 years old, there were several pieces of 0.5-1 centimeter ulcer in the several months oral cavity always since 2000, and hurt like hell is invalid with medical antibiotic therapy, the recovery from illness in 3 days of the application of the invention external used medicine.
Case 5, Chen man, 57 years old, people from Yucheng.Ate Caulis Sacchari sinensis before one week and eat cut chamber buccal mucosa, ulcer occurs, ate the Pianomide first quarter moon and do not heal, contain in addition cydiodine and lose effect, the recovery from illness in 5 days of the application of the invention external used medicine.
Case 6, Mrs Jia, 40 years old, the Shangqiu City people, the mucosa that the wisdom teeth dental caries in the upper right corner goes to burn neural rear 2 days that tooth next doors for the first time begins ulcer, take Chinese patent medicine, vitamin B2, vitamin C and the Vitamains With Minerals Tablets state of an illness and do not feel any better, the recovery from illness in 7 days of the application of the invention external used medicine.

Claims (3)

1. externally applied compound medicinal for the treatment of oral ulcer, it is to be made by the raw material of following weight portion proportioning:
14-20 parts of Margaritas, 2-5 parts of Calculus Boviss, 5-10 parts of Borneolum Syntheticums, 10-15 parts of Indigo Naturaliss, 15-20 parts of dried Alumens, 10-15 parts of Boraxs, 5-10 parts of Sanguis Draxonis, 5-10 parts in Cinnabaris, 100-200 parts of Oleum sesami.
2. a kind of externally applied compound medicinal for the treatment of oral ulcer according to claim 1 is characterized in that the weight ratio of each raw material is: 17 parts of Margaritas, 3 parts of Calculus Boviss, 7 parts of Borneolum Syntheticums; 13 parts of Indigo Naturaliss, 17 parts of dried Alumens, 13 parts of Boraxs; 7 parts of Sanguis Draxonis, 7 parts in Cinnabaris, 150 parts of Oleum sesami.
3. a kind of preparation method for the treatment of the externally applied compound medicinal of oral ulcer according to claim 1 and 2 is characterized in that: take by weighing respectively above-mentioned each medicine by prescription, then grind respectively, with Oleum sesami mix homogeneously furnishing pasty state, be.
CN201210368234.2A 2012-09-28 2012-09-28 Topical combination medicament for treating dental ulcer and preparation method thereof Expired - Fee Related CN102895472B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758505A (en) * 2015-04-02 2015-07-08 成都市飞龙水处理技术研究所青白江第一分所 Internal medicine for treating child ptyalism and preparation method of internal medicine
CN104758328A (en) * 2015-04-02 2015-07-08 成都市飞龙水处理技术研究所青白江第一分所 Powder medicine for treating severe glossitis and preparation method of powder medicine
CN105434662A (en) * 2015-12-31 2016-03-30 吕丽梅 Traditional Chinese medicine preparation for treating aphthous ulcer
CN105832942A (en) * 2016-06-03 2016-08-10 温红卫 Traditional Chinese medicine powder for treating aphtha and recurrent aphtha and preparation method thereof
CN106421493A (en) * 2016-11-30 2017-02-22 唐文龙 Traditional Chinese medicine preparation for treating dental ulcer
CN110339282A (en) * 2019-07-31 2019-10-18 吉林大学 Chinese medicine composition and preparation method thereof for treating recurrent aphthous ulcer

Citations (2)

* Cited by examiner, † Cited by third party
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CN1476885A (en) * 2003-06-10 2004-02-25 王印雄 Nianmoyankuiling for curing mucositis mucitis and its preparation
CN102038815A (en) * 2010-12-22 2011-05-04 于馥源 Oral ulcer powder

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1476885A (en) * 2003-06-10 2004-02-25 王印雄 Nianmoyankuiling for curing mucositis mucitis and its preparation
CN102038815A (en) * 2010-12-22 2011-05-04 于馥源 Oral ulcer powder

Non-Patent Citations (1)

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Title
张杰: "中医药治疗复发性口疮研究进展", 《河南中医学院学报》, vol. 1, no. 1, 31 January 2003 (2003-01-31), pages 85 - 88 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758505A (en) * 2015-04-02 2015-07-08 成都市飞龙水处理技术研究所青白江第一分所 Internal medicine for treating child ptyalism and preparation method of internal medicine
CN104758328A (en) * 2015-04-02 2015-07-08 成都市飞龙水处理技术研究所青白江第一分所 Powder medicine for treating severe glossitis and preparation method of powder medicine
CN105434662A (en) * 2015-12-31 2016-03-30 吕丽梅 Traditional Chinese medicine preparation for treating aphthous ulcer
CN105832942A (en) * 2016-06-03 2016-08-10 温红卫 Traditional Chinese medicine powder for treating aphtha and recurrent aphtha and preparation method thereof
CN106421493A (en) * 2016-11-30 2017-02-22 唐文龙 Traditional Chinese medicine preparation for treating dental ulcer
CN110339282A (en) * 2019-07-31 2019-10-18 吉林大学 Chinese medicine composition and preparation method thereof for treating recurrent aphthous ulcer

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