CN102885998B - 一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 - Google Patents
一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 Download PDFInfo
- Publication number
- CN102885998B CN102885998B CN201210433146.6A CN201210433146A CN102885998B CN 102885998 B CN102885998 B CN 102885998B CN 201210433146 A CN201210433146 A CN 201210433146A CN 102885998 B CN102885998 B CN 102885998B
- Authority
- CN
- China
- Prior art keywords
- parts
- tumor radiotherapy
- pharmaceutical composition
- medicine composition
- radiotherapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 41
- 238000001959 radiotherapy Methods 0.000 title claims abstract description 32
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 26
- 239000000203 mixture Substances 0.000 title claims abstract description 9
- 229940079593 drug Drugs 0.000 title claims description 18
- 210000001185 bone marrow Anatomy 0.000 title abstract description 6
- 230000003405 preventing effect Effects 0.000 title abstract description 4
- 230000001629 suppression Effects 0.000 title abstract 3
- 240000000599 Lentinula edodes Species 0.000 claims abstract description 9
- 235000001715 Lentinula edodes Nutrition 0.000 claims abstract description 9
- 239000007788 liquid Substances 0.000 claims description 30
- 210000000582 semen Anatomy 0.000 claims description 26
- 230000003039 myelosuppressive effect Effects 0.000 claims description 14
- 239000008194 pharmaceutical composition Substances 0.000 claims description 13
- 238000011282 treatment Methods 0.000 claims description 13
- 230000002265 prevention Effects 0.000 claims description 11
- 241000756943 Codonopsis Species 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 6
- 241000605447 Anemarrhena Species 0.000 claims description 5
- 241000545442 Radix Species 0.000 claims description 5
- 239000009636 Huang Qi Substances 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 201000011510 cancer Diseases 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 4
- 230000001965 increasing effect Effects 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 3
- 230000009467 reduction Effects 0.000 abstract description 3
- 244000144730 Amygdalus persica Species 0.000 abstract description 2
- 244000077995 Coix lacryma jobi Species 0.000 abstract description 2
- 241000830535 Ligustrum lucidum Species 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 230000004083 survival effect Effects 0.000 abstract description 2
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 241000756042 Polygonatum Species 0.000 abstract 1
- 235000008737 Polygonatum biflorum Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 210000000265 leukocyte Anatomy 0.000 description 17
- 239000012567 medical material Substances 0.000 description 16
- 210000003714 granulocyte Anatomy 0.000 description 9
- 238000004321 preservation Methods 0.000 description 9
- 230000007812 deficiency Effects 0.000 description 8
- 230000003448 neutrophilic effect Effects 0.000 description 8
- 206010011224 Cough Diseases 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 206010065553 Bone marrow failure Diseases 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 5
- 239000000706 filtrate Substances 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 230000035922 thirst Effects 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 210000001772 blood platelet Anatomy 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 201000006549 dyspepsia Diseases 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 230000002607 hemopoietic effect Effects 0.000 description 3
- 230000036407 pain Effects 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 206010040943 Skin Ulcer Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 208000031971 Yin Deficiency Diseases 0.000 description 2
- 208000019790 abdominal distention Diseases 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 238000001415 gene therapy Methods 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 201000002364 leukopenia Diseases 0.000 description 2
- 231100001022 leukopenia Toxicity 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 230000003439 radiotherapeutic effect Effects 0.000 description 2
- 238000007086 side reaction Methods 0.000 description 2
- 231100000019 skin ulcer Toxicity 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 206010001580 Albuminuria Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 235000011446 Amygdalus persica Nutrition 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000605445 Anemarrhena asphodeloides Species 0.000 description 1
- 208000032467 Aplastic anaemia Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241000208671 Campanulaceae Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241000007126 Codonopsis pilosula Species 0.000 description 1
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010013789 Dry throat Diseases 0.000 description 1
- 206010013908 Dysfunctional uterine bleeding Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 description 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 description 1
- 201000001431 Hyperuricemia Diseases 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 108010002386 Interleukin-3 Proteins 0.000 description 1
- 108090001005 Interleukin-6 Proteins 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 241000207834 Oleaceae Species 0.000 description 1
- 241001633680 Polygonatum odoratum Species 0.000 description 1
- 240000002381 Prunus davidiana Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 102000013275 Somatomedins Human genes 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010043458 Thirst Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 206010047531 Visual acuity reduced Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 239000006053 animal diet Substances 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 210000003995 blood forming stem cell Anatomy 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000003177 cardiotonic effect Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- MDZKJHQSJHYOHJ-UHFFFAOYSA-N crataegolic acid Natural products C1C(O)C(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MDZKJHQSJHYOHJ-UHFFFAOYSA-N 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 210000000222 eosinocyte Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 201000005577 familial hyperlipidemia Diseases 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- MDZKJHQSJHYOHJ-LLICELPBSA-N maslinic acid Chemical compound C1[C@@H](O)[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MDZKJHQSJHYOHJ-LLICELPBSA-N 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000037306 mature skin Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 208000007442 rickets Diseases 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 208000018556 stomach disease Diseases 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210433146.6A CN102885998B (zh) | 2012-11-05 | 2012-11-05 | 一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210433146.6A CN102885998B (zh) | 2012-11-05 | 2012-11-05 | 一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102885998A CN102885998A (zh) | 2013-01-23 |
CN102885998B true CN102885998B (zh) | 2014-01-22 |
Family
ID=47529815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210433146.6A Active CN102885998B (zh) | 2012-11-05 | 2012-11-05 | 一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102885998B (zh) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1180792C (zh) * | 2000-01-26 | 2004-12-22 | 中国石化集团齐鲁石油化工公司 | 防治白细胞减少症的中药制剂及制备工艺 |
CN1177598C (zh) * | 2001-05-24 | 2004-12-01 | 解建国 | 治疗恶性肿瘤放化疗副反应的药物及其制备方法 |
CN101181412B (zh) * | 2007-11-21 | 2011-11-23 | 翟慧 | 一种内服治疗白细胞减少症的中药 |
CN101632819B (zh) * | 2009-08-03 | 2011-05-11 | 杨春玲 | 一种对抗肺癌化疗后骨髓抑制的制剂 |
-
2012
- 2012-11-05 CN CN201210433146.6A patent/CN102885998B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN102885998A (zh) | 2013-01-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102319407B (zh) | 一种治疗胃下垂的中药及其提取方法 | |
CN102319408B (zh) | 一种健脾化湿治疗胃下垂的中药及其提取方法 | |
CN105920514A (zh) | 治疗代谢综合征的中药组合物 | |
CN104171204A (zh) | 一种调理大肠癌的茶 | |
CN101961401B (zh) | 一种具有减肥降脂健脾功效的复方中药组合物 | |
CN103736072B (zh) | 一种治疗过敏性鼻炎的药物及其制备方法 | |
CN106177053A (zh) | 一种包含青钱柳叶和陈皮的降血糖保健组合物 | |
CN102805843B (zh) | 一种治疗胃痛的药物及其制备方法 | |
CN103550506A (zh) | 一种用于放疗中配合使用的中药组合物 | |
CN102698210A (zh) | 一种健脾益气治疗胃下垂的中药 | |
CN102973895A (zh) | 一种治疗神经性呕吐的中药组合物 | |
CN102327572B (zh) | 一种平补元气治疗胃下垂的中药 | |
CN106177477A (zh) | 一种用于降血糖、降血脂和降血压的保健组合物 | |
CN102406793B (zh) | 一种治疗消化性溃疡的药物组合物 | |
CN102885998B (zh) | 一种预防或治疗肿瘤放疗引起的骨髓抑制的药物组合物 | |
CN102716426A (zh) | 一种补气养阴治疗胃下垂的中药 | |
CN105876713A (zh) | 一种养血美容富硒胡萝卜龟苓膏及其制备方法 | |
CN105902897A (zh) | 一种治疗胰腺癌的药物制剂及其用途 | |
CN105106634A (zh) | 一种治疗急性阑尾炎的中药制剂及其应用 | |
CN105213876A (zh) | 一种治疗失眠药物及其制作方法 | |
CN102274358B (zh) | 一种治疗月经提前量多乳房胀痛血块多的中药 | |
CN106038994A (zh) | 一种辅助降糖的食药及其制备方法 | |
CN108210839B (zh) | 一种辅助治疗中晚期肝癌腹水的中药 | |
CN105687474A (zh) | 癌症患者化疗期间服用的制剂及制备方法 | |
CN105106783A (zh) | 一种治疗慢性阑尾炎的中药组合物及其应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Mei Inventor after: Yang Xiaofeng Inventor before: Liu Lianhua Inventor before: Yang Xiaofeng |
|
COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: LIU LIANHUA YANG XIAOFENG TO: ZHANG MEI YANG XIAOFENG |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: NANTONG HAOYOUXIAN AQUATIC FOOD CO., LTD. Free format text: FORMER OWNER: CHEN XINGWANG Effective date: 20140728 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 276017 LINYI, SHANDONG PROVINCE TO: 226200 NANTONG, JIANGSU PROVINCE |
|
TR01 | Transfer of patent right |
Effective date of registration: 20140728 Address after: 226200 Qidong City, Jiangsu Province, Lu Lu, the Marine Economic Development Zone, four Patentee after: Nantong good and fresh aquatic food Co., Ltd. Address before: Three village Chu Dun Zhen 276017 Shandong province Linyi city Luozhuang District No. 89 group Patentee before: Chen Xingwang |