CN102885058A - Emamectin benzoate microemulsion pesticide and production technology thereof - Google Patents

Abstract

The invention discloses an emamectin benzoate microemulsion pesticide and a production technology thereof. The emamectin benzoate microemulsion pesticide comprises the following compositions in percentage by weight: 0.5-0.6% of emamectin benzoate, 8-12% of methanol, 3-5% of nonylphenol polyoxyethylene ether, 3-5% of tristyrylphenol polyoxyethylene polyoxypropylene ether, 3-5% of phenethyl cumylphenol polyoxyethylene ether and the rest amount of water; the preparation method comprises the steps of weighing, adding raw materials, stirring and other steps; the emamectin benzoate microemulsion pesticide and the production technology thereof have the advantages that the dosage form is stable, the decomposition rate is lower than 1%, the stability of the pesticide is higher than the stability of missible oil; the synergy is remarkable, the pesticide effect is improved by 30%, the formula is simple, and the production is convenient.

Description

A kind of Affirm (Merck Co.) microemulsion insecticide and production technology thereof

Technical field

The present invention relates to a kind of insecticide, specifically a kind of Affirm (Merck Co.) microemulsion insecticide and production technology thereof belong to the micro emulsion field of pesticides.

Background technology

Microemulsion is comprised of liquid pesticide, surfactant, water, stabilizing agent etc., belong to thermodynamics through the time stable dispersion, mainly take water as medium, do not contain or contain less organic solvent, thereby do not fire not quick-fried, production operation, storing is safe, low in the pollution of the environment, saves a large amount of organic solvents; The pesticide dispersion degree is high, reaches the miniaturization degree, and the agricultural chemicals particle is generally 0.1～0.01 micron, and outward appearance is similar to transparent or sub-translucent liquid; Good dispersion in water is strong to the target body permeability, adhesive force good.

Yet, the problems such as layering, crystallization, muddiness, floccule often appear in present microemulsion product in market, particularly in-20 ℃ the north, such as areas such as Heilungkiang, the Inner Mongol, also the phenomenon of freezing can occur, thereby greatly affect the development of this formulation in technical field of pesticide.In addition, the organic solvent that adds in the microemulsion--stupid kind solvent such as toluene, dimethylbenzene and stupid etc., environmental pollution is serious.Simultaneously, in the field of pesticides in the microemulsion, such as organophosphorus insecticide, pyrethrin pesticide, carbamate etc. the higher outstanding problem of resolution ratio can appear also.

Summary of the invention

In order to address the above problem, the invention provides a kind of Affirm (Merck Co.) microemulsion insecticide and production technology thereof, after adding methyl alcohol, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, phenethyl cumenyl phenol polyethenoxy ether, the product forms that obtains is stable, and good disinsection effect, synergy is remarkable, and the preparation method is simple.

Technical scheme of the present invention is:

A kind of Affirm (Merck Co.) microemulsion insecticide is grouped into by the one-tenth of following percetage by weight:

0.5-0.6% Affirm (Merck Co.), 8-12% methyl alcohol, 3-5% polyoxyethylene nonylphenol ether, 3-5% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 3-5% phenethyl cumenyl phenol polyethenoxy ether, excess water are supplied;

Preferably, the one-tenth by following percetage by weight is grouped into:

0.57% Affirm (Merck Co.), 10% methyl alcohol, 4% polyoxyethylene nonylphenol ether, 4% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 4% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

Avermectin, English name Avermectins, to have desinsection, kill ten hexa-atomic Macrocyclic lactone compounds of mite, eelworm-killing activity by university's large village intelligence in the Japanese north etc. and the class that U.S. Merck company at first develops, produced by streptomyces griseus Streptomyces avermitilis fermentation in the streptomycete, Avermectin is agricultural Insecticidal and acaricidal agent for animals, macrolide disaccharide compounds.Avermectin has insects and mites tags and stomach poison function and faint fumigation action is arranged, and lethal effect is slower.But residual less at plant surface.Avermectin is a kind of antibiotics insecticidal/acaricidal agent of efficient, wide spectrum.It is comprised of one group of macrolides compound, and active substance is AVERMECTIN, and mite class and insect are had stomach toxicity and action of contace poison.Spray leaf surface and can decompose rapidly dissipation, be present in the tissue and have conduction but infiltrate active ingredient long period in the plant parenchyma, the insect that takes food harm in evil mite and the plant tissue is had long residual effect.

Described Affirm (Merck Co.) is emamectin-benzoate, be called for short first dimension salt, it is a kind of new and effective semisynthetic antibiotics insecticide that begins to synthesize from the fermented product AVERMECTIN B1, it has super-high-efficient, low toxicity (preparation is closely nontoxic), low-residual, the nuisanceless characteristics that wait biopesticide, with Avermectin at first insecticidal activity improved 3 orders of magnitude, active high to the larva of lepidopterous insects and other many insects, existing stomach poison function is double action of contace poison again, (has good effect under 0.084 ~ 2g/ha) at low-down dosage, and in the process of pest control, beneficial insect is not injured, be conducive to the integrated control to insect, enlarge in addition insecticidal spectrum, reduced the toxicity to people and animals.

Described polyoxyethylene nonylphenol ether has another name called OP-10, and this product has good infiltration, emulsification, dispersion, antiacid, alkali resistant, anti-hard water, anti-reduction, oxidation resistance, in the present invention as emulsifier and stabilizing agent;

Described methyl alcohol claims again " another name for " or " another name for ", is the colourless volatile liquid of alcohol smell that has, for the manufacture of formaldehyde and agricultural chemicals etc., and as the denaturant of organic extractant and alcohol etc.;

Described triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, cas 99734-09-5, molecular formula C ₃₀H ₂₄O ^.(C ₂H ₄O) N, model 1601 in the present invention as emulsifier and stabilizing agent, reduces resolution ratio;

Described phenethyl cumenyl phenol polyethenoxy ether, a kind of for emulsifier, model is agricultural newborn 600-2 number, or No. 602, farming breast, uses in the present invention used as stabilizers, reduces resolution ratio.

The production technology that above-mentioned Affirm (Merck Co.) microemulsion insecticide reaches may further comprise the steps:

(1) takes by weighing each raw material according to above-mentioned prescription;

(2) first Affirm (Merck Co.) is joined in the agitator tank, again methyl alcohol is joined in the agitator tank, stir, 10 clocks;

(3) triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, phenethyl cumenyl phenol polyethenoxy ether and polyoxyethylene nonylphenol ether are joined in the agitator tank of above-mentioned steps (2), stirred 20 minutes, to fully dissolving;

(4) at last water is joined in the agitator tank of above-mentioned steps (3), stirred 20 minutes, can obtain preparation.

The invention has the advantages that: formulation is stable, after adding triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, phenethyl cumenyl phenol polyethenoxy ether and polyoxyethylene nonylphenol ether, store 60 ℃ of 60 days resolution ratios less than 1% in heat, cold storage-25 ℃ 60 days is not freezed non-crystallizable, and is higher than missible oil stability; Good disinsection effect, synergy is remarkable, than normally improving more than 30% with content prescription insecticidal effect with formulation, has greatly improved the validity of agricultural chemicals; Prescription is simple, and is convenient for production, only needs an agitator tank, and working condition requires low.

Embodiment

Below the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein only is used for description and interpretation the present invention, is not intended to limit the present invention.

Except as otherwise noted, the percentage that adopts among the present invention is percetage by weight.

Embodiment 1

A kind of Affirm (Merck Co.) microemulsion insecticide is grouped into by the one-tenth of following percetage by weight:

10.57% Affirm (Merck Co.), 10% methyl alcohol, 4% polyoxyethylene nonylphenol ether, 4% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 4% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

Described Affirm (Merck Co.) is emamectin-benzoate.

The result:

Be 0.3% in 60 ℃ of 60 days resolution ratios of heat storage, cold storage-25 ℃ 60 days is not freezed non-crystallizable;

Synergy is remarkable: by comparative trial, preparation of the present invention is compared with the insecticide of former medicine content with formulation with routine, and other condition is identical, and insecticidal effect increases by 35%.

Embodiment 2

A kind of Affirm (Merck Co.) microemulsion insecticide is grouped into by the one-tenth of following percetage by weight:

0.5% Affirm (Merck Co.), 8% methyl alcohol, 3% polyoxyethylene nonylphenol ether, 3% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 3% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

Described Affirm (Merck Co.) is emamectin-benzoate.

The result:

Be 0.7% in 60 ℃ of 60 days resolution ratios of heat storage, cold storage-25 ℃ 60 days is not freezed non-crystallizable;

Synergy is remarkable: by comparative trial, preparation of the present invention is compared with the insecticide of former medicine content with formulation with routine, and other condition is identical, and insecticidal effect increases by 35%.

Embodiment 3

A kind of Affirm (Merck Co.) microemulsion insecticide is grouped into by the one-tenth of following percetage by weight:

0.6% Affirm (Merck Co.), 12% methyl alcohol, 5% polyoxyethylene nonylphenol ether, 5% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 5% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

The result:

Described Affirm (Merck Co.) is emamectin-benzoate.

Be 0.5% in 60 ℃ of 60 days resolution ratios of heat storage, cold storage-25 ℃ 60 days is not freezed non-crystallizable;

Synergy is remarkable: by comparative trial, preparation of the present invention is compared with the insecticide of former medicine content with formulation with routine, and other condition is identical, and insecticidal effect increases by 30%.

Embodiment 4

The production technology of the described microemulsion insecticide of a kind of embodiment 1-3 may further comprise the steps:

(1) takes by weighing each raw material according to above-mentioned prescription;

(2) first Affirm (Merck Co.) is joined in the agitator tank, again methyl alcohol is joined in the agitator tank, stir, 10 clocks;

(3) triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, phenethyl cumenyl phenol polyethenoxy ether and polyoxyethylene nonylphenol ether are joined in the agitator tank of above-mentioned steps (2), stirred 20 minutes, to fully dissolving;

(4) at last water is joined in the agitator tank of above-mentioned steps (3), stirred 20 minutes, can obtain preparation.

Among each embodiment of the present invention, used chemical industry material is used material in the production of this area, all can obtain from market, and can not exert an influence for the production result; The equipment of using in each operation all adopts conventional equipment used in the current production, there is no special feature.

It should be noted that at last: the above only is the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment the present invention is had been described in detail, for a person skilled in the art, it still can be made amendment to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (5)

1. Affirm (Merck Co.) microemulsion insecticide, it is characterized in that: the one-tenth by following percetage by weight is grouped into:

0.5-0.6% Affirm (Merck Co.), 8-12% methyl alcohol, 3-5% polyoxyethylene nonylphenol ether, 3-5% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 3-5% phenethyl cumenyl phenol polyethenoxy ether, excess water.

2. microemulsion insecticide according to claim 1, it is characterized in that: the one-tenth by following percetage by weight is grouped into:

0.57% Affirm (Merck Co.), 10% methyl alcohol, 4% polyoxyethylene nonylphenol ether, 4% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 4% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

3. microemulsion insecticide according to claim 1, it is characterized in that: the one-tenth by following percetage by weight is grouped into:

0.5% Affirm (Merck Co.), 8% methyl alcohol, 3% polyoxyethylene nonylphenol ether, 3% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 3% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

4. microemulsion insecticide according to claim 1, it is characterized in that: the one-tenth by following percetage by weight is grouped into:

0.6% Affirm (Merck Co.), 12% methyl alcohol, 5% polyoxyethylene nonylphenol ether, 5% triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, 5% phenethyl cumenyl phenol polyethenoxy ether, water complementary.

5. the production technology such as the described microemulsion insecticide of claim 1-4 any one is characterized in that, may further comprise the steps:

(1) takes by weighing each raw material according to above-mentioned prescription;

(2) first Affirm (Merck Co.) is joined in the agitator tank, again methyl alcohol is joined in the agitator tank, stir, 10 clocks;

(3) triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, phenethyl cumenyl phenol polyethenoxy ether and polyoxyethylene nonylphenol ether are joined in the agitator tank of above-mentioned steps (2), stirred 20 minutes, to fully dissolving;

(4) at last water is joined in the agitator tank of above-mentioned steps (3), stirred 20 minutes, can obtain preparation.