CN102884177A - Cd49f通过pi3k/akt/gsk3途径促进成体干细胞的增殖、专能性和重编程 - Google Patents
Cd49f通过pi3k/akt/gsk3途径促进成体干细胞的增殖、专能性和重编程 Download PDFInfo
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
- G01N2333/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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Abstract
Description
Claims (25)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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KR20100014771 | 2010-02-18 | ||
KR10-2010-0014771 | 2010-02-18 | ||
PCT/KR2011/001103 WO2011102680A2 (ko) | 2010-02-18 | 2011-02-18 | Pi3k/akt/gsk3 경로를 통해 성체줄기세포의 증식, 다분화능 및 재프로그래밍을 촉진하는 cd49f |
Publications (2)
Publication Number | Publication Date |
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CN102884177A true CN102884177A (zh) | 2013-01-16 |
CN102884177B CN102884177B (zh) | 2015-06-10 |
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CN201180019732.XA Active CN102884177B (zh) | 2010-02-18 | 2011-02-18 | Cd49f通过pi3k/akt/gsk3途径促进成体干细胞的增殖、专能性和重编程 |
Country Status (5)
Country | Link |
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US (1) | US9139812B2 (zh) |
EP (1) | EP2537922B1 (zh) |
KR (2) | KR20110095218A (zh) |
CN (1) | CN102884177B (zh) |
WO (1) | WO2011102680A2 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112739208A (zh) * | 2018-09-21 | 2021-04-30 | 艾普斯丹医疗公司 | 人类多能成体干细胞 |
CN113853443A (zh) * | 2019-03-08 | 2021-12-28 | 株式会社Neogentc | 用于预测淋巴细胞的肿瘤反应性的标志物及其用途 |
Families Citing this family (3)
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US10557120B2 (en) * | 2013-07-26 | 2020-02-11 | Kyoto Prefectural Public University Corporation | Osteoblast and method for preparing same |
CN106687582A (zh) | 2014-08-04 | 2017-05-17 | 堪萨斯大学 | 哺乳动物多能干细胞、其产生方法及其用途 |
US20220145241A1 (en) * | 2019-02-25 | 2022-05-12 | Nippon Shokubai Co., Ltd. | Method for producing cell spheroids |
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IT1302534B1 (it) * | 1998-12-21 | 2000-09-05 | Fidia Advanced Biopolymers Srl | Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per |
EP1540348A4 (en) | 2002-08-27 | 2006-10-11 | Stemcells California Inc | ENRICHED CELLS OF STEM CELLS AND PROGENITORS OF THE CENTRAL NERVOUS SYSTEM, AND METHODS OF IDENTIFYING, ISOLATING AND ENRICHING SUCH POPULATIONS |
US20090181087A1 (en) * | 2003-12-19 | 2009-07-16 | Viacell, Inc. | Use of human cord blood-derived pluripotent cells for the treatment of disease |
US20060030042A1 (en) * | 2003-12-19 | 2006-02-09 | Ali Brivanlou | Maintenance of embryonic stem cells by the GSK-3 inhibitor 6-bromoindirubin-3'-oxime |
US20060205075A1 (en) * | 2005-03-10 | 2006-09-14 | Kyoto University | In vitro differentiation and maturation of mouse embryonic stem cells into hepatocytes |
KR100679642B1 (ko) * | 2005-11-16 | 2007-02-06 | 주식회사 알앤엘바이오 | 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제 |
EP2099290A4 (en) * | 2006-12-07 | 2010-01-13 | Teva Pharma | PROCESS FOR GENERATING AND EXPANDING PROGENITOR CELLS OF TISSUES AND TISSUE CELLS MILLED FROM INTACT BONE MARROW OR UMBILICAL INTACT CORD TISSUE |
WO2009069991A2 (en) * | 2007-11-30 | 2009-06-04 | Rnl Bio Co., Ltd. | Cellular therapeutic agent for incontinence of urine comprising stem cells originated from decidua or adipose |
WO2009154770A2 (en) * | 2008-06-18 | 2009-12-23 | The Texas A & M University System | Mesenchymal stem cells, compositions, and methods for treatment of cardiac tissue damage |
KR101204894B1 (ko) * | 2008-07-14 | 2012-11-26 | (주)마리아 바이오텍 | 줄기세포의 외배엽성 세포로의 분화 방법 |
-
2011
- 2011-02-18 WO PCT/KR2011/001103 patent/WO2011102680A2/ko active Application Filing
- 2011-02-18 US US13/638,262 patent/US9139812B2/en active Active
- 2011-02-18 CN CN201180019732.XA patent/CN102884177B/zh active Active
- 2011-02-18 EP EP11744922.3A patent/EP2537922B1/en active Active
- 2011-02-18 KR KR20110014817A patent/KR20110095218A/ko active Application Filing
-
2018
- 2018-10-29 KR KR1020180130162A patent/KR102150244B1/ko active IP Right Grant
Non-Patent Citations (4)
Title |
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LAWSON,D.A.ET AL: "Isolation and functional characterization of murine prostate stem cells", 《PROC。NATL.ACAD.SCI》 * |
LEE,R.H.ET AL: "The CD34-like protein PODXL and α6-integrin(CD49f)identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice", 《BLOOD》 * |
LIXIN,ET AL: "Self-Renewal and Multilineage Differentiation In Vitro from Murine Prostate Stem Cells", 《STEM CELLS》 * |
TOMA,J.G. ET AL: "Isolation of multipotent adult stem cells from the dermis of mamalian skin", 《NATURE CELL BIOLOGY》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112739208A (zh) * | 2018-09-21 | 2021-04-30 | 艾普斯丹医疗公司 | 人类多能成体干细胞 |
CN113853443A (zh) * | 2019-03-08 | 2021-12-28 | 株式会社Neogentc | 用于预测淋巴细胞的肿瘤反应性的标志物及其用途 |
Also Published As
Publication number | Publication date |
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EP2537922A2 (en) | 2012-12-26 |
EP2537922A4 (en) | 2014-01-22 |
US9139812B2 (en) | 2015-09-22 |
WO2011102680A9 (ko) | 2011-11-17 |
WO2011102680A3 (ko) | 2012-02-02 |
CN102884177B (zh) | 2015-06-10 |
EP2537922B1 (en) | 2021-04-21 |
KR20110095218A (ko) | 2011-08-24 |
KR102150244B1 (ko) | 2020-09-02 |
WO2011102680A2 (ko) | 2011-08-25 |
KR20180120657A (ko) | 2018-11-06 |
US20130089885A1 (en) | 2013-04-11 |
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