CN102866663B - Method for automatically storing and calling production process parameters - Google Patents
Method for automatically storing and calling production process parameters Download PDFInfo
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- CN102866663B CN102866663B CN201210367007.8A CN201210367007A CN102866663B CN 102866663 B CN102866663 B CN 102866663B CN 201210367007 A CN201210367007 A CN 201210367007A CN 102866663 B CN102866663 B CN 102866663B
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 54
- 238000000034 method Methods 0.000 title claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 119
- 239000002994 raw material Substances 0.000 claims abstract description 38
- 229940079593 drug Drugs 0.000 claims abstract description 17
- 239000002552 dosage form Substances 0.000 claims description 4
- 238000004321 preservation Methods 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 abstract description 11
- 238000003860 storage Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/26—Programme control arrangements
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- Medical Treatment And Welfare Office Work (AREA)
Abstract
The invention discloses a method for automatically storing and calling production process parameters, belonging to the technical field of medicine production. The method is characterizedin that constructing a medicine (production) process parameter matrix which is based on historical data and is used for reflecting five types of factors, namely different medicine types, different raw materials used by different medicines, different production batches of different raw materials, the proportions of the medicines of various raw materials in each production batch and process parameters of each production batch is constructed, wherein only if a user sequentially compares the medicine type lists, the medicine raw material lists and the proportion lists of the medicine raw materials in the medicine process parameter matrix of the current medicines to be produced with corresponding lists in the medicine process parameter matrix of the similar medicines in a medicine process parameter database, and if the lists are completely the same, a computer can control the production according to the process parameters and control programs in the medicine process parameter database constructed on the basis of the historical data; and if the lists are different, the computer controls the production according to the medicine process parameter matrix input into the computer and the corresponding process parameter and the control program. By the method, a series of problems caused by manual operation during actual production are solved.
Description
Technical field
The invention belongs to production technology, relate in particular to pharmaceutical production technical field
Background technology
Sheeter is to meet necessarily required dryness graininess or powder material by moving up and down and the mould of circumference rotation is pressed into the machine of tablet under the effect of pinch roller.Have simple to operate, be convenient to cleaning, be applicable to the wide feature of medicament, be widely used in pharmaceutical industry.In actual production, need to record various technological parameters owing to changing pharmacy variety, even if produce the medicament of same kind, the technological parameter using due to raw material batch difference is also not quite similar.Medicine technological parameter is inconsistent, and technological parameter is many, cause technological parameter storage, input all to rely on manpower to complete, for medicine of the same race on the one hand, be unfavorable for the technique reproduction of product between criticizing, cause differences between batches large, be unfavorable for production quality control, for different medicines, easily cause technological parameter entanglement on the other hand.
Summary of the invention
The object of the present invention is to provide a kind of automatic preservation and call the method for processing parameter, large to solve differences between batches, the wayward and caused variety of issue hand-manipulated of product quality.
The invention is characterized in, in computing machine, realize according to the following steps successively:
Step (1), computer initialization: preset in the medicine technological parameter database of using in pharmaceutical production: the medicine technological parameter group that the pharmaceutical production of the same dosage form of the different cultivars medicine of once producing is in history used, it is a binary symbol sequence, be called W sequence, be expressed as: W={A, B, C, D, E}, wherein:
A, is one group of binit, represents the title of various different medicines, represents the sequence number of different medicines, a=1,2,3 with a ... A, A is numerically equal to the sum of various different medicines,
B, is one group of binit, represents contained various raw material in certain medicine, represents the sequence number of this raw material, b=1,2,3 with b ... B, B is numerically equal to the sum of various different materials contained in described certain medicine,
C, is one group of binit, represents the production batch of various raw materials contained in described certain medicine, represents the sequence number of certain raw material production batch, c=1,2,3 with c ... C, C is numerically equal to the sum of the different production batch of certain raw material,
D, it is one group of binit, the sequence number of the proportioning of the raw material that represents to belong in described certain medicine certain production batch in the medicine of this production batch, represent with d, d=1,2,3 ... D, D is numerically equal to the sum of described certain medicine certain raw material different proportionings used in certain production batch used
E, is one group of binary number, represents certain medicine technological parameter group used in certain production batch c, wherein at least comprises and is subject to the described computer-controlled various i of topworks
c, the position i that topworks will arrive
c, s, the rotating speed i of topworks
c, n, processing temperature and tonnage, wherein:
I
c, represent the topworks that certain production batch c sequence number used is i, i
c=1,2,3 ..., I
c, I
cbe numerically equal to the sum of this production batch topworks used, deposit the each corresponding control program corresponding to described medicine technological parameter group W simultaneously in;
Step (2) is at moment t, and user is to the medicine technological parameter group W of the current medicine a producing of described computer input
t, a, step (3) computing machine judges in described medicine technological parameter database, whether there is described medicine technological parameter group W
a,
If: there is not described medicine technological parameter group W
a,
Send steering order by described medicine technological parameter group W
t, aproduce, and described technological parameter group W
t, adeposit described medicine technological parameter database in,
If: there is described medicine technological parameter group W
a, execution step (4),
Step (4) computing machine judges medicine technological parameter group Wa and the Wt described in two, a:
If: the two is identical, and press the corresponding control program of medicine technological parameter group of Wa and produce,
If: the two difference,
, by the medicine technological parameter group Wt of current input, a produces, and production batch number is added to 1, described Wt, and a and corresponding control program deposit described medicine technological parameter database in,
When user in step (2) is to the current medicine technological parameter group Wt of described computer input, when a is a sequence decimally representing, computing machine will increase a step that decimal sequence is converted to corresponding binary sequence.
For the different dosage form of same kind medicine, the topworks using and the kind of technological parameter and quantity are different, for the medicine of same formulation, for the enterprise determining, the kind of the topworks using and quantity are identical, and wherein said topworks is any in converter plant, servomechanism installation, stepper motor.
It is loaded down with trivial details that the present invention can solve technique storage in actual production, and the shortcoming of easily makeing mistakes and being inconvenient to transfer, is convenient to control drug quality, enhances productivity.
Accompanying drawing explanation
The structural representation of Fig. 1 medicine technological parameter tree.
Fig. 2 program flow chart of the present invention.
Embodiment
A matrix representation for medicine technological parameter group of a kind of medicine of the present invention, the wherein medicine technological parameter of a kind of medicine of each line display, each row from left to right represents the title of medicine successively, the raw material that various medicines are used, the production batch of every kind of raw material, in each production batch, various raw materials are in the proportioning without in product, and each batch of corresponding technological parameter, have 5 row, thereby the matrix that the medicine technological parameter group of described various medicines is formed to a 4*5, is called medicine technological parameter matrix.
The medicine technological parameter of each medicine in described medicine technological parameter matrix can with a medicine technological parameter tree representation as shown in Figure 1:
The first row represents nomenclature of drug a, two kinds of raw materials that the second line display medicine a is used, the third line represents the production batch separately of two kinds of raw materials in medicine a, fourth line represents in medicine a the proportioning of various raw materials in medicine in each production batch, all raw materials that fifth line represents medicine a technological parameter used in each production batch.
User inputs the nomenclature of drug of current production product with a decimal expression corresponding to binary number, by that analogy, input successively the decimal expression of various raw materials corresponding to binary expression formula, a kind of raw material production batch is corresponding to the decimal expression of binary expression formula, batch representing with C+1 now, the decimal expression corresponding to binary expression formula of each raw material in the medicine of current production in described C+1 production batch, and the decimal expression corresponding with the binary expression formula of the technological parameter in this production batch, after numeral system switching, thereby be combined into one and calculate the medicine technological parameter matrix that function is carried out.
As long as successively corresponding row in the medicine technological parameter matrix of same medicine same formulation in the technological parameter matrix Raw row of the current medicine that need to produce, proportioning row, technological parameter row and described medicine technological parameter database are compared one by one, just can determine and in described medicine technological parameter database, whether have identical medicine technological parameter group, if identical, produce by control program corresponding in described medicine technological parameter database, otherwise, produce by the control program of new input, and storage, its main program flow is shown in Fig. 2.
Below, as follows to the symbol description in Fig. 1:
A
,represent certain medicine a,
B
1, arepresent the raw material that in certain medicine a, sequence number is 1,
B
b,arepresent the raw material that in certain medicine a, sequence number is B, B=2,
C
1, b1, arepresent the raw material b of certain medicine a
1middle sequence number is 1 production batch,
C
c, b1, arepresent the raw material b of certain medicine a
1middle sequence number is the production batch of C, C=2,
C
1, b2, a, c
2, b2, aanalogize,
D
1, c1, b1, arepresent the raw material b of certain medicine a
1middle sequence number is 1 production batch Raw b
1proportioning, d
2, c1, b1, a, d
2, c2, b1, a, d
2, c1, b2,
a, d
2, c2, b2, aanalogize
D
d, c, b, a represents the raw material b of C batch
1proportioning in corresponding medicine bottle raw material proportioning, D=2, d
1, c
1, b
2, a, d
d, c, b
2, a analogizes
E
1, c1, ba, arepresent that medicine a is at c
1technological parameter group used in inferior production batch, E=2,
E
e, c, ba, arepresent the technological parameter group of the use of medicine a in c production batch, b
awhole raw materials of medicine a, b
a=b
1, a, b
2, a ... b
b, a.
Claims (3)
1. a method of automatically preserving and call processing parameter, is characterized in that, in computing machine, realizes according to the following steps successively:
Step (1), computer initialization: preset in the medicine technological parameter database of using in pharmaceutical production: the medicine technological parameter group that the pharmaceutical production of the same dosage form of the different cultivars medicine of once producing is in history used, it is a binary symbol sequence, be called W sequence, be expressed as: W={A, B, C, D, E}, wherein:
A, is one group of binit, represents the title of various different medicines, represents the sequence number of different medicines, a=1,2,3 with a ... A, A is numerically equal to the sum of various different medicines,
B, is one group of binit, represents contained various raw material in certain medicine, represents the sequence number of this raw material, b=1,2,3 with b ... B, B is numerically equal to the sum of various different materials contained in described certain medicine,
C, is one group of binit, represents the production batch of various raw materials contained in described certain medicine, represents the sequence number of certain raw material production batch, c=1,2,3 with c ... C, C is numerically equal to the sum of the different production batch of certain raw material,
D, it is one group of binit, the sequence number of the proportioning of the raw material that represents to belong in described certain medicine certain production batch in the medicine of this production batch, represent with d, d=1,2,3 ... D, D is numerically equal to the sum of described certain medicine certain raw material different proportionings used in certain production batch used
E, is one group of binary number, represents certain medicine technological parameter group used in certain production batch c, wherein at least comprises and is subject to the described computer-controlled various i of topworks
c, the position i that topworks will arrive
c, s, the rotating speed i of topworks
c, n, processing temperature and tonnage, wherein:
I
c, represent the topworks that certain production batch c sequence number used is i, i
c=1,2,3 ..., I
c, I
cbe numerically equal to the sum of this production batch topworks used, deposit the each corresponding control program corresponding to described medicine technological parameter group W simultaneously in;
Step (2) is at moment t, and user is to the medicine technological parameter group W of the current medicine a producing of described computer input
t, a, step (3) computing machine judges in described medicine technological parameter database, whether there is described medicine technological parameter group W
a,
If: there is not described medicine technological parameter group W
a,
Send steering order by described medicine technological parameter group W
t, aproduce, and described technological parameter group W
t, adeposit described medicine technological parameter database in,
If: there is described medicine technological parameter group W
a, execution step (4),
Step (4) computing machine judges medicine technological parameter group Wa and the Wt described in two, a:
If: the two is identical, and press the corresponding control program of medicine technological parameter group of Wa and produce,
If: the two difference,
, by the medicine technological parameter group Wt of current input, a produces, and production batch number is added to 1, described Wt, and a and corresponding control program deposit described medicine technological parameter database in.
2. a kind of automatic preservation according to claim 1 and call the method for processing parameter, is characterized in that, when in step
(2) in, user is to the current medicine technological parameter group Wt of described computer input, and when a is a sequence decimally representing, computing machine will increase a step that decimal sequence is converted to corresponding binary sequence.
3. a kind of automatic preservation according to claim 1 and call the method for processing parameter, it is characterized in that, for the different dosage form of same kind medicine, the topworks using and the kind of technological parameter and quantity are different, for the medicine of same formulation, for the enterprise determining, the kind of the topworks using and quantity are identical, and wherein said topworks is any in converter plant, servomechanism installation, stepper motor.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210367007.8A CN102866663B (en) | 2012-09-28 | 2012-09-28 | Method for automatically storing and calling production process parameters |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210367007.8A CN102866663B (en) | 2012-09-28 | 2012-09-28 | Method for automatically storing and calling production process parameters |
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| CN102866663A CN102866663A (en) | 2013-01-09 |
| CN102866663B true CN102866663B (en) | 2014-06-11 |
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| EP3229090A1 (en) * | 2016-04-04 | 2017-10-11 | FELSS Systems GmbH | Method performed by means of a computer system for planning a manufacturing process and computer program and a computer system for carrying out the method |
| CN112418570A (en) * | 2019-08-19 | 2021-02-26 | 阿里巴巴集团控股有限公司 | Production process sheet generation method and device |
| CN113110366B (en) * | 2021-06-10 | 2021-09-03 | 浙江大胜达包装股份有限公司 | Wireless Internet of things system and method for corrugated paper production process control |
| CN113255159B (en) * | 2021-06-16 | 2021-10-08 | 浙江大胜达包装股份有限公司 | Automatic paper product packaging matching design method and system based on cost model |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3698947B2 (en) * | 2000-03-27 | 2005-09-21 | 日立ソフトウエアエンジニアリング株式会社 | Database processing method and database processing system |
| US8166048B2 (en) * | 2005-06-27 | 2012-04-24 | Informatica Corporation | Method and apparatus for data integration and management |
| CN102542143A (en) * | 2010-12-27 | 2012-07-04 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Method and device for acquiring and storing process data, and system for processing process data |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20020128998A1 (en) * | 2001-03-07 | 2002-09-12 | David Kil | Automatic data explorer that determines relationships among original and derived fields |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3698947B2 (en) * | 2000-03-27 | 2005-09-21 | 日立ソフトウエアエンジニアリング株式会社 | Database processing method and database processing system |
| US8166048B2 (en) * | 2005-06-27 | 2012-04-24 | Informatica Corporation | Method and apparatus for data integration and management |
| CN102542143A (en) * | 2010-12-27 | 2012-07-04 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Method and device for acquiring and storing process data, and system for processing process data |
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Inventor after: Zhang Hao Inventor after: Wan Cheng Inventor before: Wan Cheng |
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Free format text: CORRECT: INVENTOR; FROM: WAN CHENG TO: ZHANG HAO WAN CHENG |
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Granted publication date: 20140611 |