CN102866663A - Method for automatically storing and calling production process parameters - Google Patents
Method for automatically storing and calling production process parameters Download PDFInfo
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- CN102866663A CN102866663A CN2012103670078A CN201210367007A CN102866663A CN 102866663 A CN102866663 A CN 102866663A CN 2012103670078 A CN2012103670078 A CN 2012103670078A CN 201210367007 A CN201210367007 A CN 201210367007A CN 102866663 A CN102866663 A CN 102866663A
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 54
- 238000000034 method Methods 0.000 title claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 119
- 239000002994 raw material Substances 0.000 claims abstract description 38
- 229940079593 drug Drugs 0.000 claims abstract description 16
- 239000002552 dosage form Substances 0.000 claims description 4
- 238000004321 preservation Methods 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 abstract description 11
- 238000003860 storage Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/26—Programme control arrangements
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- Medical Treatment And Welfare Office Work (AREA)
Abstract
The invention discloses a method for automatically storing and calling production process parameters, belonging to the technical field of medicine production. The method is characterizedin that constructing a medicine (production) process parameter matrix which is based on historical data and is used for reflecting five types of factors, namely different medicine types, different raw materials used by different medicines, different production batches of different raw materials, the proportions of the medicines of various raw materials in each production batch and process parameters of each production batch is constructed, wherein only if a user sequentially compares the medicine type lists, the medicine raw material lists and the proportion lists of the medicine raw materials in the medicine process parameter matrix of the current medicines to be produced with corresponding lists in the medicine process parameter matrix of the similar medicines in a medicine process parameter database, and if the lists are completely the same, a computer can control the production according to the process parameters and control programs in the medicine process parameter database constructed on the basis of the historical data; and if the lists are different, the computer controls the production according to the medicine process parameter matrix input into the computer and the corresponding process parameter and the control program. By the method, a series of problems caused by manual operation during actual production are solved.
Description
Technical field
The invention belongs to production technology, relate in particular to the pharmaceutical production technical field
Background technology
Sheeter is to meet necessarily required dryness graininess or powder material by moving up and down and the mould of circumference rotation is pressed into the machine of tablet under the effect of pinch roller.Have simple to operately, be convenient to cleaning, be fit to the wide characteristics of medicament, be widely used in pharmaceutical industry.In actual production, need to record various technological parameters owing to change pharmacy variety, even produce the medicament of same kind, because the different employed technological parameters of raw material batch also are not quite similar.The medicine technological parameter is inconsistent, and technological parameter is many, cause technological parameter storage, input all to rely on manpower to finish, for medicine of the same race on the one hand, the technique reproduction of product causes differences between batches large between being unfavorable for criticizing, and is unfavorable for production quality control, for different medicines, cause easily the technological parameter entanglement on the other hand.
Summary of the invention
The object of the present invention is to provide a kind of automatic preservation and call the method for processing parameter, large to solve differences between batches, product quality caused variety of issue wayward and hand-manipulated.
The invention is characterized in, in computing machine, realize according to the following steps successively:
Step (1), computer initialization: in the medicine technological parameter database that pharmaceutical production is used, preset: the medicine technological parameter group that the pharmaceutical production of the same dosage form of the different cultivars medicine of once producing is in history used, it is a binary symbol sequence, be called the W sequence, be expressed as: W={A, B, C, D, E}, wherein:
A is one group of binit, represents the title of various different medicines, represents the sequence number of different medicines, a=1,2,3 with a ... A, A are numerically equal to the sum of various different medicines,
B is one group of binit, represents contained various raw material in certain medicine, represents the sequence number of this raw material, b=1,2,3 with b ... B, B are numerically equal to the sum of various different materials contained in described certain medicine,
C is one group of binit, represents the production batch of various raw materials contained in described certain medicine, represents the sequence number of certain raw material production batch, c=1,2,3 with c ... C, C are numerically equal to the sum of the different production batch of certain raw material,
D, it is one group of binit, represent to belong in described certain medicine the sequence number of the proportioning of raw material in the medicine of this production batch of certain production batch, represent with d, d=1,2,3 ... D, D is numerically equal to the sum of used certain raw material used different proportionings in certain production batch of described certain medicine
E is one group of binary number, represents certain medicine used technological parameter group in certain production batch c, wherein comprises at least being subjected to the described computer-controlled various i of topworks
c, the position i that topworks will arrive
c, s, the rotating speed i of topworks
c, n, processing temperature and tonnage, wherein:
i
c, represent that the used sequence number of certain production batch c is the topworks of i, i
c=1,2,3 ..., I
c, I
cBe numerically equal to the sum of the used topworks of this production batch, deposit simultaneously each the corresponding control program corresponding to described medicine technological parameter group W in;
Step (2) is at moment t, and the user is to the medicine technological parameter group W of the current medicine a that is producing of described computer input
T, a,,
Step (3) computing machine judges whether there is described medicine technological parameter group W in described medicine technological parameter database
a,
If: there is not described medicine technological parameter group W
a,
Then send steering order by described medicine technological parameter group W
T, aProduce, and described technological parameter group W
T, aDeposit described medicine technological parameter database in,
If: there is described medicine technological parameter group W
a, execution in step (4) then,
Step (4) computing machine is judged two described medicine technological parameter group Wa and Wt, a:
If: the two is identical, then presses the corresponding control program production of medicine technological parameter group of Wa,
If: the two difference,
Then by the medicine technological parameter group Wt of current input, a produces, and the production batch number is added 1, described Wt, and a and corresponding control program deposit described medicine technological parameter database in.
As the current medicine technological parameter group Wt of user in step (2) to described computer input, when a was the sequence of a decimally expression, computing machine will increase a step that decimal sequence is converted to corresponding binary sequence.
Different dosage form for same kind medicine, the kind of employed topworks and technological parameter is different with quantity, medicine for same formulation, for an enterprise that determines, the kind of employed topworks is identical with quantity, and wherein said topworks is any in converter plant, servomechanism installation, the stepper motor.
The technique storage that the present invention can solve in actual production is loaded down with trivial details, and the shortcoming of makeing mistakes easily and being inconvenient to transfer is convenient to control drug quality, enhances productivity.
Description of drawings
The structural representation of Fig. 1 medicine technological parameter tree.
Fig. 2 program flow chart of the present invention.
Embodiment
The medicine technological parameter group of a kind of medicine of the present invention is with a matrix representation, the medicine technological parameter of a kind of medicine of each line display wherein, each row from left to right represents the title of medicine successively, the raw material that various medicines are used, the production batch of every kind of raw material, various raw materials are without the proportioning in the product in each production batch, and the corresponding technological parameter of each batch, have 5 row, thereby the matrix a 4*5 of the medicine technological parameter group of described various medicines formation is called medicine technological parameter matrix.
The medicine technological parameter of each medicine in the described medicine technological parameter matrix can be with a medicine technological parameter tree representation as shown in Figure 1:
The first row represents nomenclature of drug a, two kinds of raw materials that the second line display medicine a is used, the third line represents the production batch separately of two kinds of raw materials among the medicine a, fourth line represents among the medicine a proportioning of various raw materials in medicine in each production batch, all raw materials that fifth line represents medicine a used technological parameter in each production batch.
The user inputs the nomenclature of drug of current production product with a decimal expression corresponding to binary number, by that analogy, input successively various raw materials corresponding to the decimal expression of binary expression formula, a kind of raw material production batch is corresponding to the decimal expression of binary expression formula, batch representing with C+1 of this moment, the decimal expression corresponding to binary expression formula of each raw material in the medicine of current production in the described C+1 production batch, and the decimal expression corresponding with the binary expression formula of technological parameter in this production batch, after the numeral system switching, calculate the medicine technological parameter matrix that function is carried out thereby be combined into one.
As long as successively corresponding row in the medicine technological parameter matrix of same medicine same formulation in the technological parameter matrix Raw row of the current medicine that need to produce, proportioning row, technological parameter row and the described medicine technological parameter database are compared one by one, just can determine whether identical medicine technological parameter group is arranged in the described medicine technological parameter database, if identical, then produce by control program corresponding in the described medicine technological parameter database, otherwise, control program production by new input, and storage, its main program flow is seen Fig. 2.
Below, as follows to the symbol description among Fig. 1:
A represents certain medicine a,
b
1, aRepresent that sequence number among certain medicine a is 1 raw material,
b
B, aRepresent that sequence number is the raw material of B among certain medicine a, B=2,
c
1, b1, aThe raw material b that represents certain medicine a
1Middle sequence number is 1 production batch,
c
C, b1, aThe raw material b that represents certain medicine a
1Middle sequence number is the production batch of C, C=2,
c
1, b2, a, c
2, b2, aAnalogize,
d
1, c1, b1, aThe raw material b that represents certain medicine a
1Middle sequence number is 1 production batch Raw b
1Proportioning, d
2, c1, b1, a, d
2, c2, b1, a, d
2, c1, b2, a, d
2, c2, b2, aAnalogize
d
D, c1, b, a represent C batch raw material b
1Proportioning in corresponding medicine bottle raw material proportioning, D=2, d
1, c
1, b
2, a, d
D, c, b
2, a analogizes
e
1, c1, ba, aExpression medicine a is at c
1Used technological parameter group in the inferior production batch, E=2,
e
E, c, ba, aThe technological parameter group of the usefulness of expression medicine a in c production batch, b
aWhole raw materials of medicine a, b
a=b
1, a, b
2, a ... b
B, a.
Claims (3)
1. the method for automatically preserving and calling processing parameter is characterized in that, realizes according to the following steps successively in computing machine:
Step (1), computer initialization: in the medicine technological parameter database that pharmaceutical production is used, preset: the medicine technological parameter group that the pharmaceutical production of the same dosage form of the different cultivars medicine of once producing is in history used, it is a binary symbol sequence, be called the W sequence, be expressed as: W={A, B, C, D, E}, wherein:
A is one group of binit, represents the title of various different medicines, represents the sequence number of different medicines, a=1,2,3 with a ... A, A are numerically equal to the sum of various different medicines,
B is one group of binit, represents contained various raw material in certain medicine, represents the sequence number of this raw material, b=1,2,3 with b ... B, B are numerically equal to the sum of various different materials contained in described certain medicine,
C is one group of binit, represents the production batch of various raw materials contained in described certain medicine, represents the sequence number of certain raw material production batch, c=1,2,3 with c ... C, C are numerically equal to the sum of the different production batch of certain raw material,
D, it is one group of binit, represent to belong in described certain medicine the sequence number of the proportioning of raw material in the medicine of this production batch of certain production batch, represent with d, d=1,2,3 ... D, D is numerically equal to the sum of used certain raw material used different proportionings in certain production batch of described certain medicine
E is one group of binary number, represents certain medicine used technological parameter group in certain production batch c, wherein comprises at least being subjected to the described computer-controlled various i of topworks
c, the position i that topworks will arrive
c, s, the rotating speed i of topworks
c, n, processing temperature and tonnage, wherein:
i
c, represent that the used sequence number of certain production batch c is the topworks of i, i
c=1,2,3 ..., I
c, I
cBe numerically equal to the sum of the used topworks of this production batch, deposit simultaneously each the corresponding control program corresponding to described medicine technological parameter group W in;
Step (2) is at moment t, and the user is to the medicine technological parameter group W of the current medicine a that is producing of described computer input
T, a,,
Step (3) computing machine judges whether there is described medicine technological parameter group W in described medicine technological parameter database
a,
If: there is not described medicine technological parameter group W
a,
Then send steering order by described medicine technological parameter group W
T, aProduce, and described technological parameter group W
T, aDeposit described medicine technological parameter database in,
If: there is described medicine technological parameter group W
a, execution in step (4) then,
Step (4) computing machine is judged two described medicine technological parameter group Wa and Wt, a:
If: the two is identical, then presses the corresponding control program production of medicine technological parameter group of Wa,
If: the two difference,
Then by the medicine technological parameter group Wt of current input, a produces, and the production batch number is added 1, described Wt, and a and corresponding control program deposit described medicine technological parameter database in.
2. a kind of automatic preservation according to claim 1 and call the method for processing parameter is characterized in that, when in step
(2) user is to the current medicine technological parameter group Wt of described computer input in, and when a was the sequence of a decimally expression, computing machine will increase a step that decimal sequence is converted to corresponding binary sequence.
3. a kind of automatic preservation according to claim 1 and call the method for processing parameter, it is characterized in that, different dosage form for same kind medicine, the kind of employed topworks and technological parameter is different with quantity, medicine for same formulation, for an enterprise that determines, the kind of employed topworks is identical with quantity, and wherein said topworks is any in converter plant, servomechanism installation, the stepper motor.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107272594A (en) * | 2016-04-04 | 2017-10-20 | 菲尔斯系统有限责任公司 | Plan method and its program and system of execution that the computer system of technique is performed |
CN113110366A (en) * | 2021-06-10 | 2021-07-13 | 浙江大胜达包装股份有限公司 | Wireless Internet of things system and method for corrugated paper production process control |
CN113255159A (en) * | 2021-06-16 | 2021-08-13 | 浙江大胜达包装股份有限公司 | Automatic paper product packaging matching design method and system based on cost model |
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JP3698947B2 (en) * | 2000-03-27 | 2005-09-21 | 日立ソフトウエアエンジニアリング株式会社 | Database processing method and database processing system |
US8166048B2 (en) * | 2005-06-27 | 2012-04-24 | Informatica Corporation | Method and apparatus for data integration and management |
CN102542143A (en) * | 2010-12-27 | 2012-07-04 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Method and device for acquiring and storing process data, and system for processing process data |
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- 2012-09-28 CN CN201210367007.8A patent/CN102866663B/en not_active Expired - Fee Related
Patent Citations (4)
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JP3698947B2 (en) * | 2000-03-27 | 2005-09-21 | 日立ソフトウエアエンジニアリング株式会社 | Database processing method and database processing system |
US20020128998A1 (en) * | 2001-03-07 | 2002-09-12 | David Kil | Automatic data explorer that determines relationships among original and derived fields |
US8166048B2 (en) * | 2005-06-27 | 2012-04-24 | Informatica Corporation | Method and apparatus for data integration and management |
CN102542143A (en) * | 2010-12-27 | 2012-07-04 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Method and device for acquiring and storing process data, and system for processing process data |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107272594A (en) * | 2016-04-04 | 2017-10-20 | 菲尔斯系统有限责任公司 | Plan method and its program and system of execution that the computer system of technique is performed |
CN113110366A (en) * | 2021-06-10 | 2021-07-13 | 浙江大胜达包装股份有限公司 | Wireless Internet of things system and method for corrugated paper production process control |
CN113255159A (en) * | 2021-06-16 | 2021-08-13 | 浙江大胜达包装股份有限公司 | Automatic paper product packaging matching design method and system based on cost model |
CN113255159B (en) * | 2021-06-16 | 2021-10-08 | 浙江大胜达包装股份有限公司 | Automatic paper product packaging matching design method and system based on cost model |
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Inventor after: Zhang Hao Inventor after: Wan Cheng Inventor before: Wan Cheng |
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Free format text: CORRECT: INVENTOR; FROM: WAN CHENG TO: ZHANG HAO WAN CHENG |
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Granted publication date: 20140611 |