Background technology
Tinsel is widely used in medical apparatus and instruments, in straight cuts, titanium clamp pincers (vascular forceps) apparatus product etc. under various anastomats, stiching instrument, straight cuts, the chamber mirror, these medical apparatus and instruments are usually used in the operations such as the coincideing of the tissue such as surgery stomach, lung and operation on digestive tract tissue, stitching.But, because used biologically inert wiry can have a negative impact to sewing effect when oozing of blood appears in seam area.When tinsel and the organization healing around it, wire surface character is to organizing pivotal role.In operation, because tinsel need to carry out stitching to tissue, in conjunctive tissue, also need tissue is carried out bactericidal antiphlogistic on every side, but still do not have to carry out tissue at present the medical metal silk of effective bactericidal antiphlogistic.
Summary of the invention
The present invention aims to provide a kind of medical metal silk with antibacterial-anti-inflammatory drug coating.
For achieving the above object, the technical solution adopted in the present invention is: a kind of medical metal silk comprises metal body, it is characterized in that, it also comprises medication coat, and the composition of medication coat is nanometer silver and Hyaluronic Acid, and described medication coat is coated in the surface of described metal body.
Preferably, described medication coat also contains chitosan.
Preferably, the thickness of described medication coat is 0.001-10mm.
Preferably, the diameter of medical metal silk is 0.001-20mm.
Preferably, the main component of described metal body is titanium or rustless steel.
The medication coat of medical metal silk surface-coated of the present invention can to carrying out bactericidal antiphlogistic around the tissue, promote the regeneration of tissue in conjunctive tissue, can effectively promote the healing of organizing.
The specific embodiment
Medical metal silk of the present invention is for cutting assembly, disposable stiching instrument, single-use skin anastomat, the anus-expanding unit anastomat with light source, disjunctor anastomat, string suture stapling device, clamp anastomat, closing of cutting anastomat, perforator, arc-shaped cutting anastomat etc. under cutting, the chamber mirror under tube type anastomat, Linear stapler, disposable suturing assembly, the chamber mirror.
The diameter of medical metal silk is 0.001-20mm, and the main component of metal body can be titanium or rustless steel, and rustless steel can be 12Cr18Ni9,316,316L etc.
Fig. 1 is the profile of the medical metal silk of one embodiment of the present of invention.
As shown in Figure 1, the scheme of embodiments of the invention employing is at metal body 1 surface-coated medication coat 2 wiry.
The composition of medication coat 2 is nanometer silver and Hyaluronic Acid.
Medication coat 2 can also contain chitosan.
The painting method of medication coat 2 is: compounding pharmaceutical solution, tinsel is immersed in the solution, and soak time and solution concentration determine that according to coating layer thickness requiring coating layer thickness is 0.001-10mm, take out tinsel and carry out dried.
The present invention can realize by the following examples.
Embodiment 1
Hyaluronic Acid is dissolved in the water, makes 15% solution, according to nanometer silver: solution is that 1: 1000 ratio adds nanometer silver, makes the suspension of nanometer silver.Tinsel is immersed in the nanometer silver suspension of making.Take out tinsel after soaking, carry out natural drying or dry in freezer dryer, obtain the tinsel of surface-coated nanometer silver and Hyaluronic Acid medication coat 2.
Embodiment 2
Chitosan is dissolved in the water, makes 20% solution A.Hyaluronic Acid is dissolved in the water, makes 13% solution B.Solution A is mixed according to 6: 1 ratio with solution B, make solution C.In solution C according to nanometer silver: solution C is that 1: 800 ratio adds nanometer silver, makes suspension D.Tinsel is immersed among the aforementioned suspension D, and soaked 3 minutes; Take out tinsel, natural drying or dry in freezer dryer obtains the tinsel that surface-coated contains the medication coat 2 of nanometer silver, Hyaluronic Acid and chitosan.
The medication coat of medical metal silk surface-coated of the present invention can in conjunctive tissue, to carrying out bactericidal antiphlogistic around the tissue, promote regeneration and the healing of tissue.
The U-shaped that is shaped as wiry of above-described embodiment, medical metal silk of the present invention can be made various shapes as required.The cross section of medical metal silk can be circle, flat and other shape that needs.
Above-described embodiment is the formal specification the specific embodiment of the present invention with example; those skilled in the art can make according to above-described embodiment the scheme of various variations; such as the shape of medical metal silk is made various distortion; reasonably in the scope component ratio of soak is being made change; the scheme of these variations all will obtain the medical metal silk that surface-coated contains described medication coat; all do not break away from spirit of the present invention and flesh and blood, all fall within protection scope of the present invention.