CN102838063B - Pre-encapsulating glass syringe vacuum plugging method - Google Patents
Pre-encapsulating glass syringe vacuum plugging method Download PDFInfo
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- CN102838063B CN102838063B CN201210374264.4A CN201210374264A CN102838063B CN 102838063 B CN102838063 B CN 102838063B CN 201210374264 A CN201210374264 A CN 201210374264A CN 102838063 B CN102838063 B CN 102838063B
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Abstract
The invention discloses a pre-encapsulating glass syringe vacuum plugging method which comprises the following steps of: (1) loading a liquid product tool plate into a box; (2) tool positioning: clamping a part of edge of a glass syringe tool plate in a stage of positioning clamp trough of a positioning tool plate; (3) rubber plug charging tool plate positioning: placing a rubber plug tool plate filled with rubber plugs on the upper part of the glass syringe tool plate, and clamping a part of edge of the rubber plug tool plate in the other stage of positioning clamp trough of the positioning tool plate; (4) closing a door of the box body; (5) pumping with vacuum to eliminate liquid medicine bubbles; (6) releasing pressure and charging plugs; and (7) encapsulating. According to the pre-encapsulating glass syringe vacuum plugging method, air in the lower part of the liquid medicine in a glass syringe can all be exhausted to avoid the overflowing of the liquid medicine, and the lower edge of the rubber plug connected with a push rod in the a syringe is just contacted with the upper surface of the liquid medicine, so that when the glass syringe is used, after a packing is opened and a syringe needle is loaded, the syringe can be directly used by pushing the push rod, and the pre-encapsulating glass syringe vacuum plugging method has the advantages of time saving, working efficiency improvement, use safety improvement of the liquid medicine and is suitable for long-distance transport and long-time storage.
Description
Technical field
The present invention relates to a kind of medicine equipment householder method, especially a kind of pre-filled glass syringe vacuum adds blocking method.
Background technology
The development experience of syringe all-glass syringe and plastic injector for temporary use, the connection of its needle tubing conehead and syringe needle is to complete by the needle stand of metal or plastics.This class syringe can not be stored liquid for a long time, therefore, when use, even if need to make up a prescription topping up, injects.Current most of liquid is by other packaged media, and then transfer use, and the transfer potential of liquid must cause Liquid Residue waste, and especially, to few costly medicine and a biologics etc. of use amount, this problem is more outstanding, seriously increases liquid user's expense; On the other hand, there is serious problem in the destruction of such syringe and use management, and reusable problem is difficult to be solved, seriously polluted, and harmfulness is large.
For this reason, people have invented pre-filled medicinal liquid injector, a kind ofly in advance the liquid of respective amount are filled in syringe at before sales.Because plastics itself are easily corroded by liquid, also likely there is the effusion of plastic monomer, cause liquid medicine contamination, and the liquid medicine that some are long placed in, can not carry out high-temperature sterilization lamp shortcoming, so the syringe of this type of material is not suitable for the storage of liquid.
Occurred in the market can pre-filled medicinal liquid glass syringe, for example: the Chinese patent 200810139640.5 of applicant's earlier application of the application discloses a kind of Vitrea pre-filled medicinal liquid injector; Chinese patent ZL97206093.6 discloses a kind of disposable syringe of liquid drug in advance, and what it adopted is also glass syringe; Application number is that 200910249086.0 Chinese patent application discloses a kind of glass syringe with retractable needle.
Although above Patent Application Publication glass syringe that can pre-filled medicinal liquid, how but not openly liquid is not preliminary filling, and according to applicant's market study, pre-filled medicinal liquid there will be the air chamber of formation foremost at syringe at present, when use, by promoting push rod, gas is discharged again, there will be following problem, the one, in order to ensure that gas all discharges, a part of liquid must be discharged, because amount of liquid medicine is considerably less, be difficult to grasp, and most of liquid is expensive, waste more serious; The 2nd, the existence meeting of gas pollutes liquid, causes liquid to lose efficacy, so that user's health is worked the mischief.
On the other hand, also have and adopt in the time of pre-embedding liquid, promoting liquid by push rod moves ahead, by Bas Discharged, the same existence of this mode is all discharged in order to ensure gas, a part of liquid must be discharged, because amount of liquid medicine is considerably less, be difficult to grasp, and most of liquid is expensive, waste is necessary serious.
Summary of the invention
The object of the invention is for overcoming above-mentioned the deficiencies in the prior art, provide a kind of pre-filled glass syringe vacuum to add blocking method, the method can be by vacuum principle effectively by Bas Discharged, and can not cause liquid to flow out, and can make the plug lower edge connected with push rod in syringe just in time contact with liquid upper surface.
For achieving the above object, the present invention adopts following technical proposals:
A kind of pre-filled glass syringe vacuum adds blocking method, and step is as follows:
1) dress liquid product working plate cartonning; Seal cap is combined in to glass syringe front end and forms compound glass syringe, then compound glass syringe is packed in the hole of glass syringe working plate, and to liquid drug in compound glass syringe; Door on casing is opened, then the glass syringe working plate that occupies compound glass syringe is positioned on the positioning board in casing;
2) tool locating; The part edge of glass syringe working plate is stuck in the wherein one-level locating groove of positioning board;
3) add plug working plate location; The plug working plate that occupies rubber piston is positioned over to glass syringe working plate top, and the part edge of plug working plate is stuck in another grade of locating groove of positioning board;
4) cabinet door sealing, and locking, owing to being provided with sealing member between the door of casing and box side, can make in casing in a closed environment;
5) vacuumize, eliminate liquid bubble; Controller control vacuum generator work, makes in casing in vacuum environment, and air pressure in the casing negative pressure that reaches capacity, thereby the air of the liquid bottom in glass syringe is all discharged, and reaches enclosed liquid the inside without bubble;
6) release of pressure is jumped a queue; Controller control cylinder piston rod is descending, promote subplate and jump a queue base plate along guide upright post down sliding, the drive guide rod of jumping a queue presses down with rubber piston and contacts, promote rubber piston and enter in glass syringe, by controller control downstream rate and downstream position, in the time that the lower surface of rubber piston contacts with the liquid upper surface in glass syringe just, stop cylinder piston descending, and to change service direction be up, drive the guide rod of jumping a queue to recover initial position, one-period completes;
7) open cabinet door, take out the glass syringe that has placed rubber piston, push rod is screwed in rubber piston, encapsulation.
Workflow of the present invention is: and dress liquid product working plate cartonning-tool locating-Jia plug working plate location-cabinet door seals-vacuumizes-and elimination liquid bubble-release of pressure jumps a queue and taken out product.Detailed content is as follows:
Seal cap is combined in to glass syringe front end and forms compound glass syringe, then compound glass syringe is packed in the hole of glass syringe working plate, and to liquid drug in compound glass syringe.Door on casing is opened, again the glass syringe working plate that occupies compound glass syringe is positioned on the positioning board in casing, and the part edge of glass syringe working plate is stuck in the wherein one-level locating groove of positioning board, the compound glass syringe that can make glass syringe working plate and wherein place keeps good stability in the time of work disposal, be conducive to improve crudy, improving product qualification rate.Glass syringe working plate is a flat board, which is provided with some holes of matching with compound glass syringe, when work, multiple compound glass syringes is positioned over respectively in each hole, and the flange of compound glass syringe upper end is just in time stuck in the edge in hole.
Place after the glass syringe working plate that occupies compound glass syringe, again the plug working plate that occupies rubber piston is positioned over to glass syringe working plate top, and the part edge that makes plug working plate is stuck in another grade of locating groove of positioning board, the rubber piston that can make plug working plate and wherein place keeps good stability in the time of work disposal, and can make rubber piston and combination syringe align, be conducive to improve crudy, improving product qualification rate.Rubber piston quantity equates with compound glass syringe quantity, and each rubber piston is corresponding up and down with each compound glass syringe.Plug working plate is also a slab construction, which is provided with some holes, places rubber piston in hole.
The guide rod of jumping a queue of plugging organization is corresponding one by one with rubber piston, and the diameter of the guide rod of jumping a queue is less than the diameter in hole on plug working plate, can directly stretch in this hole, and rubber piston can be depressed.
Then close the door of casing, and locking, owing to being provided with sealing member between the door of casing and box side, can make in casing in a closed environment.Sealing member can be rubber seal.Controller control vacuum generator work, makes in casing in vacuum environment, and air pressure in the casing negative pressure that reaches capacity, thereby the air of the liquid bottom in glass syringe is all discharged, and reaches enclosed liquid the inside without bubble.
Controller control cylinder piston rod is descending, promote subplate and jump a queue base plate along guide upright post down sliding, the drive guide rod of jumping a queue presses down with rubber piston and contacts, promoting rubber piston enters in glass syringe, by controller control downstream rate and downstream position, in the time that the lower surface of rubber piston contacts with the liquid upper surface in glass syringe just, stop cylinder piston descending, and to change service direction be up, drive jump a queue guide rod recover initial position, one-period completes, open cabinet door, take out the glass syringe that has placed rubber piston, push rod is screwed in rubber piston, encapsulation.
The vacuum stopper-adding machine that the present invention is used, comprise the casing of sealing, casing be provided with one can folding door, the side plate contact position of door and casing is provided with sealing member, in described casing, the sidewall of middle and lower part is provided with positioning board, and positioning board top is provided with plugging organization, and casing side is provided with an interface being connected with external vacuum producer, and interface communicates with box house, described plugging organization is all connected with controller by wire with vacuum generator.Door is transparent translation door or transparent clamshell doors.Positioning board is on the sidewall being horizontally placed in casing, and on positioning board, is respectively equipped with and holds the glass syringe working plate of glass syringe syringe and place the dual-positioning groove that the plug locating plate of rubber piston matches.Plugging organization comprises the guide upright post parallel with two of the cylinder on the top board that is fixed on casing, described cylinder is positioned at casing outside, two parallel guide upright posts are positioned at box house, the piston rod of cylinder stretches in casing, piston-rod end be enclosed within guide upright post on and the adding device that can move up and down along it be connected.Adding device comprises the subplate being fixedly connected with piston-rod end, and the both sides of described subplate are enclosed within on guide upright post respectively, and subplate is fixedly connected with the slip cap being enclosed within on guide upright post; Described subplate bottom is connected with the base plate of jumping a queue by attaching parts, described in the base plate both sides of jumping a queue be also enclosed within respectively on guide upright post, the base plate bottom of jumping a queue is provided with some guide rods of jumping a queue that be arranged in parallel.Subplate be arranged in parallel with the base plate of jumping a queue.Attaching parts is thru-bolt, and the two ends of thru-bolt are individually fixed in subplate and jump a queue on base plate.Some guide rods of jumping a queue need rubber piston to be processed corresponding with its underpart respectively.Controller is industrial computer or micro controller system or PLC.
The invention has the beneficial effects as follows, the present invention adopts technique scheme, can make the air of glass syringe herb liquid bottom all discharge, and avoids liquid to overflow, and the plug lower edge connected with push rod in syringe just in time contacts with liquid upper surface.When medical personnel located is used, unpack, install syringe needle, promoting push rod can directly use, and need not worry to contain air bubble problem inside liquid again, has saved the time, improve work efficiency, promoted liquid and used safety, suitable long-distance transport and long-time storage.
Brief description of the drawings
Fig. 1 is structural representation of the present invention (door opening state);
Fig. 2 is lateral plan of the present invention;
Wherein 1. casings, 2. sealing member, 3., 4. interface, 5. cylinder, 6. guide upright post, 7. power seat, 8. slip cap, 9. subplate, the base plate of 10. jumping a queue, 11. guide rods of jumping a queue, 12. rubber pistons, 13. plug working plates, 14. positioning boards, 15. glass syringe working plates, 16. glass syringes, 17. seal caps.
Detailed description of the invention
Below in conjunction with drawings and Examples, the present invention is further described.
Workflow of the present invention is: dress liquid product working plate cartonning-tool locating-add plug working plate location-cabinet door seal-vacuumizes-eliminate liquid bubble-release of pressure product of jumping a queue-taken out.Detailed operation flow process is as follows:
Place after the glass syringe working plate 15 that occupies compound glass syringe, again the plug working plate 13 that occupies rubber piston 12 is positioned over to glass syringe working plate 15 tops, and the part edge that makes plug working plate 13 is stuck in another grade of locating groove of positioning board 14, the rubber piston 12 that can make plug working plate 13 and wherein place keeps good stability in the time of work disposal, and can make rubber piston 12 and compound glass syringe align, be conducive to improve crudy, improving product qualification rate.Rubber piston 12 quantity equate with compound glass syringe quantity, and each rubber piston 12 is corresponding up and down with each compound glass syringe.Plug working plate 13 is also a slab construction, which is provided with some holes, places rubber piston 12 in hole.
The guide rod 11 of jumping a queue of plugging organization is corresponding one by one with rubber piston 12, and the diameter of the guide rod 11 of jumping a queue is less than the diameter in hole on plug working plate 13, can directly stretch in this hole, and rubber piston 12 can be depressed.
Then close the door 3 of casing 1, and locking, owing to being provided with sealing member 2 between the door 3 of casing 1 and box side, can make in casing 1 in a closed environment.Sealing member 2 can be rubber seal.Controller control vacuum generator work, makes in casing 1 in vacuum environment, and air pressure in casing 1 negative pressure that reaches capacity, thereby the air of the liquid bottom in glass syringe is all discharged, and reaches enclosed liquid the inside without bubble.
Controller control cylinder piston rod is descending, promote subplate 9 and jump a queue base plate 10 along guide upright post 6 down slidings, the drive guide rod 11 of jumping a queue presses down with rubber piston 12 and contacts, promoting rubber piston 12 enters in glass syringe, by controller control downstream rate and downstream position, in the time that the lower surface of rubber piston 12 contacts with the liquid upper surface in glass syringe just, stop cylinder piston descending, and to change service direction be up, the drive guide rod 11 of jumping a queue recovers initial position, one-period completes, open cabinet door 3, take out the glass syringe that has placed rubber piston 12, push rod is screwed in rubber piston 12, encapsulation.
When medical personnel located is used, unpack, install syringe needle, promoting push rod can directly use, and need not worry to contain air bubble problem inside liquid again, has saved the time, improve work efficiency, promoted liquid and used safety, suitable long-distance transport and long-time storage.
Vacuum stopper-adding machine of the present invention, as shown in Figure 1, 2, comprises the casing 1 of sealing, casing 1 be provided with one can folding door 3, door 3 is transparent translation door or transparent clamshell doors.The side plate contact position of door 3 and casing 1 is provided with sealing member 2, the sidewall of described casing 1 interior middle and lower part is provided with positioning board 14, positioning board 14 tops are provided with plugging organization, casing 1 side is provided with an interface 4 being connected with external vacuum producer, and interface 4 communicates with casing 1 inside, and described plugging organization is all connected with controller by wire with vacuum generator.Controller is industrial computer or micro controller system or PLC.
Positioning board 14 is for being horizontally placed on the sidewall in casing 1, and on positioning board 14, is respectively equipped with and holds the glass syringe working plate 15 of glass syringe syringe 16 and place the dual-positioning groove that the plug locating plate 13 of rubber piston 12 matches.
Plugging organization comprises the guide upright post 6 parallel with two of the cylinder 5 on the top board that is fixed on casing 1, described cylinder 5 is positioned at casing 1 outside, two parallel guide upright posts 6 are positioned at casing 1 inside, the piston rod of cylinder 5 stretches in casing 1, piston-rod end be enclosed within guide upright post 6 on and the adding device that can move up and down along it be connected.Adding device comprises the subplate 9 being fixedly connected with by power seat 7 with piston-rod end, and the both sides of subplate 9 are enclosed within respectively on guide upright post 6, and subplate 9 is fixedly connected with the slip cap 8 being enclosed within on guide upright post 6; Subplate 9 bottoms are connected with the base plate 10 of jumping a queue by attaching parts, and base plate 10 both sides of jumping a queue are also enclosed within respectively on guide upright post 6, and base plate 10 bottoms of jumping a queue are provided with some guide rods 11 of jumping a queue that be arranged in parallel.Subplate 9 be arranged in parallel with the base plate 10 of jumping a queue.Attaching parts is thru-bolt, and the two ends of thru-bolt are individually fixed in subplate 9 and jump a queue on base plate 10.Some guide rods 11 of jumping a queue need rubber piston 12 to be processed corresponding with its underpart respectively.
By reference to the accompanying drawings the specific embodiment of the present invention is described although above-mentioned; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendments that creative work can make or distortion still in protection scope of the present invention.
Claims (1)
1. a pre-filled glass syringe vacuum adds blocking method, it is characterized in that, the pre-filled glass syringe vacuum stopper-adding machine that the method adopts comprises the casing of sealing, casing be provided with one can folding door, the side plate contact position of door and casing is provided with sealing member, in described casing, the sidewall of middle and lower part is provided with positioning board, positioning board top is provided with plugging organization, casing side is provided with an interface being connected with external vacuum producer, and interface communicates with box house, described plugging organization is all connected with controller by wire with vacuum generator;
Described positioning board is on the sidewall being horizontally placed in casing, and on positioning board, is respectively equipped with and holds the glass syringe working plate of glass syringe syringe and place the dual-positioning groove that the plug locating plate of rubber piston matches;
Described plugging organization comprises the guide upright post parallel with two of the cylinder on the top board that is fixed on casing, described cylinder is positioned at casing outside, two parallel guide upright posts are positioned at box house, the piston rod of cylinder stretches in casing, piston-rod end be enclosed within guide upright post on and the adding device that can move up and down along it be connected;
Described adding device comprises the subplate being fixedly connected with piston-rod end, and the both sides of described subplate are enclosed within on guide upright post respectively, and subplate is fixedly connected with the slip cap being enclosed within on guide upright post; Described subplate bottom is connected with the base plate of jumping a queue by attaching parts, described in the base plate both sides of jumping a queue be also enclosed within respectively on guide upright post, the base plate bottom of jumping a queue is provided with some guide rods of jumping a queue that be arranged in parallel;
The step that adds blocking method is as follows:
1) dress liquid product working plate cartonning; Seal cap is combined in to glass syringe front end and forms compound glass syringe, then compound glass syringe is packed in the hole of glass syringe working plate, and to liquid drug in compound glass syringe; Door on casing is opened, then the glass syringe working plate that occupies compound glass syringe is positioned on the positioning board in casing;
2) tool locating; The part edge of glass syringe working plate is stuck in the wherein one-level locating groove of positioning board;
3) add plug working plate location; The plug working plate that occupies rubber piston is positioned over to glass syringe working plate top, and the part edge of plug working plate is stuck in another grade of locating groove of positioning board;
4) cabinet door sealing, and locking, owing to being provided with sealing member between the door of casing and box side, can make in casing in a closed environment;
5) vacuumize, eliminate liquid bubble; Controller control vacuum generator work, makes in casing in vacuum environment, and air pressure in the casing negative pressure that reaches capacity, thereby the air of the liquid bottom in glass syringe is all discharged, and reaches enclosed liquid the inside without bubble;
6) release of pressure is jumped a queue; Controller control cylinder piston rod is descending, promote subplate and jump a queue base plate along guide upright post down sliding, the drive guide rod of jumping a queue presses down with rubber piston and contacts, promote rubber piston and enter in glass syringe, by controller control downstream rate and downstream position, in the time that the lower surface of rubber piston contacts with the liquid upper surface in glass syringe just, stop cylinder piston descending, and to change service direction be up, drive the guide rod of jumping a queue to recover initial position, one-period completes;
7) open cabinet door, take out the glass syringe that has placed rubber piston, push rod is screwed in rubber piston, encapsulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210374264.4A CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210374264.4A CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102838063A CN102838063A (en) | 2012-12-26 |
| CN102838063B true CN102838063B (en) | 2014-06-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210374264.4A Expired - Fee Related CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
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| CN (1) | CN102838063B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103832961B (en) * | 2014-02-20 | 2015-12-30 | 温州市吉诺机械有限公司 | The filling all-in-one that vacuumizes and jump a queue of syringe |
| CN104229188B (en) * | 2014-08-28 | 2016-08-17 | 上海上药新亚药业有限公司 | A kind of total head plug antibiotic bottle gradient method evacuation process and device |
| CN108423207B (en) * | 2018-03-28 | 2020-04-21 | 上海亚力机械科技有限公司 | Syringe pre-filling device |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0735186B2 (en) * | 1992-08-03 | 1995-04-19 | 株式会社アキュレックス | Vacuum stopper machine |
| CN2795181Y (en) * | 2005-01-17 | 2006-07-12 | 中山博泰药械有限公司 | Medicine bottle pressurizing and sealing device |
| CN201358164Y (en) * | 2009-01-19 | 2009-12-09 | 湖南科伦制药有限公司 | Novel air-charging stopper-adding equipment |
| CN202007111U (en) * | 2011-03-31 | 2011-10-12 | 山东滨州博莱威生物技术有限公司 | High-speed rectilinear filling and plugging machine for preparing animal vaccines |
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- 2012-09-29 CN CN201210374264.4A patent/CN102838063B/en not_active Expired - Fee Related
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| CN102838063A (en) | 2012-12-26 |
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