CN102838063A - Pre-encapsulating glass syringe vacuum plugging method - Google Patents
Pre-encapsulating glass syringe vacuum plugging method Download PDFInfo
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- CN102838063A CN102838063A CN2012103742644A CN201210374264A CN102838063A CN 102838063 A CN102838063 A CN 102838063A CN 2012103742644 A CN2012103742644 A CN 2012103742644A CN 201210374264 A CN201210374264 A CN 201210374264A CN 102838063 A CN102838063 A CN 102838063A
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Abstract
The invention discloses a pre-encapsulating glass syringe vacuum plugging method which comprises the following steps of: (1) loading a liquid product tool plate into a box; (2) tool positioning: clamping a part of edge of a glass syringe tool plate in a stage of positioning clamp trough of a positioning tool plate; (3) rubber plug charging tool plate positioning: placing a rubber plug tool plate filled with rubber plugs on the upper part of the glass syringe tool plate, and clamping a part of edge of the rubber plug tool plate in the other stage of positioning clamp trough of the positioning tool plate; (4) closing a door of the box body; (5) pumping with vacuum to eliminate liquid medicine bubbles; (6) releasing pressure and charging plugs; and (7) encapsulating. According to the pre-encapsulating glass syringe vacuum plugging method, air in the lower part of the liquid medicine in a glass syringe can all be exhausted to avoid the overflowing of the liquid medicine, and the lower edge of the rubber plug connected with a push rod in the a syringe is just contacted with the upper surface of the liquid medicine, so that when the glass syringe is used, after a packing is opened and a syringe needle is loaded, the syringe can be directly used by pushing the push rod, and the pre-encapsulating glass syringe vacuum plugging method has the advantages of time saving, working efficiency improvement, use safety improvement of the liquid medicine and is suitable for long-distance transport and long-time storage.
Description
Technical field
The present invention relates to a kind of medicine equipment householder method, especially a kind of preparatory embedding glass syringe vacuum adds blocking method.
Background technology
All-glass syringe and plastic injector for temporary use have been experienced in the development of syringe, and the needle stand that being connected of its needle tubing conehead and syringe needle be to lean on metal or plastics is accomplished.This type syringe can not be stored soup for a long time, therefore, during use, even need to make up a prescription topping up, injects.Present most of soup is through other packaged media, and then shifts and use, and the transfer potential of soup must cause the debris waste, and especially to few costly medicine of one-shot usage amount and biologics etc., this problem is more outstanding, seriously increases soup user's expense; On the other hand, there are serious problem in the destruction of such syringe and use and management, and reusable problem is difficult to be solved, and is seriously polluted, and harmfulness is big.
For this reason, people have invented pre-filled medicinal liquid injector, promptly a kind ofly promptly are filled to the soup of respective amount in the syringe in advance at before sales.Because plastics itself are corroded by soup easily, the effusion of plastic monomer also might occur, cause liquid medicine contamination, and, can not carry out high-temperature sterilization lamp shortcoming, so the not storage of suitable soup of the syringe of this type of material to some liquid medicines of putting for a long time.
Occurred in the market can pre-filled medicinal liquid glass syringe, for example: the application's applicant discloses a kind of Vitrea pre-filled medicinal liquid injector at the Chinese patent 200810139640.5 of first to file; Chinese patent ZL97206093.6 discloses a kind of disposable syringe of liquid drug in advance, and what it adopted also is glass syringe; Application number is that 200910249086.0 one Chinese patent application discloses a kind of glass syringe with retractable needle.
Though above patent application disclose can pre-filled medicinal liquid glass syringe, how openly soup is not a preliminary filling, and according to applicant's market study; Pre-filled medicinal liquid can appear at air chamber of formation foremost of syringe at present, during use, through promoting push rod gas is discharged again; Following problem can appear, and the one, all discharge in order to guarantee gas, must a part of soup be discharged; Because amount of liquid medicine is considerably less; Be difficult to grasp, and most of soup costs an arm and a leg, waste more serious; The 2nd, the existence meeting of gas pollutes soup, causes soup to lose efficacy, so that user's health is worked the mischief.
On the other hand, when also being employed in preparatory embedding soup, promoting liquid through push rod and move ahead; With air exhaustion, the same existence of this mode is all discharged in order to guarantee gas, must a part of soup be discharged; Because amount of liquid medicine is considerably less; Be difficult to grasp, and most of soup costs an arm and a leg, waste is necessary serious.
Summary of the invention
The objective of the invention is for overcoming the deficiency of above-mentioned prior art; Provide a kind of preparatory embedding glass syringe vacuum to add blocking method; This method can be through the vacuum principle effectively with air exhaustion; And can not cause liquid to flow out, and the plug lower edge that links to each other with push rod in the syringe is just in time contacted with the soup upper surface.
For realizing above-mentioned purpose, the present invention adopts following technical proposals:
A kind of preparatory embedding glass syringe vacuum adds blocking method, and step is following:
1) dress liquid product frock plate cartonning; Seal cap is combined in glass syringe front end forms combination glass syringe, will make up the glass needle wound packages again and go in the hole of glass syringe frock plate, and in making up the glass syringe liquid drug; Door on the casing is opened, and the glass syringe frock plate that will occupy combination glass syringe again is positioned on the positioning tool plate in the casing;
2) tool locating; The part edge of glass syringe frock plate is stuck in the wherein one-level locating groove of positioning tool plate;
3) add plug frock plate location; Be positioned over glass syringe frock plate top to the plug frock plate that occupies rubber piston, and the part edge of plug frock plate is stuck in another grade locating groove of positioning tool plate;
4) cabinet door sealing, and locking owing to be provided with sealing member between the door of casing and the box side, can make to be in the casing in the closed environment;
5) vacuumize, eliminate the soup bubble; The work of controller control vacuum generator makes to be in vacuum environment in the casing, and the negative pressure that reaches capacity of the air pressure in the casing, thereby the air of the soup bottom in the glass syringe is all discharged, and reaches the no bubble in enclosed liquid the inside;
6) release of pressure is jumped a queue; Controller control cylinder piston rod is descending, promote subplate with the base plate of jumping a queue along guide upright post to lower slider, drive the guide rod of jumping a queue and press down with rubber piston and contact; Promote rubber piston and get in the glass syringe, by controller control downstream rate and downstream position, when the lower surface of rubber piston just with the glass syringe in soup upper surface when contacting; It is descending to stop cylinder piston; And to change service direction be up, drives the guide rod of jumping a queue and recover initial position, and one-period is accomplished;
7) open cabinet door, take out the glass syringe that has placed rubber piston, push rod is screwed in the rubber piston, encapsulation gets final product.
Workflow of the present invention is: dress liquid product frock plate cartonning-tool locating-Jia plug frock plate location-cabinet door seals-vacuumizes-eliminates soup bubble-release of pressure taking-up completion product of jumping a queue.Detailed content is following:
Seal cap is combined in glass syringe front end forms combination glass syringe, will make up the glass needle wound packages again and go in the hole of glass syringe frock plate, and in making up the glass syringe liquid drug.Door on the casing is opened; The glass syringe frock plate that will occupy combination glass syringe again is positioned on the positioning tool plate in the casing; And the part edge of glass syringe frock plate is stuck in the wherein one-level locating groove of positioning tool plate; The combination glass syringe that can make glass syringe frock plate and wherein place keeps stability preferably when work disposal, help improving crudy, promotes product quality.Glass syringe frock plate is a flat board, which is provided with some holes of matching with combination glass syringe, during work, a plurality of combination glass syringes is positioned over respectively in each hole, and the flange of combination glass syringe upper end just in time is stuck in the edge in hole.
After placing the glass syringe frock plate that occupies combination glass syringe; Be positioned over glass syringe frock plate top to the plug frock plate that occupies rubber piston again; And the part edge that makes plug frock plate is stuck in another grade locating groove of positioning tool plate, can make plug frock plate and the rubber piston wherein placed keeps stability preferably when work disposal, and can make rubber piston and make up syringe and align; Help improving crudy, promote product quality.Rubber piston quantity equates that with combination glass syringe quantity each rubber piston is corresponding up and down with each combination glass syringe.Plug frock plate also is a slab construction, which is provided with some holes, places rubber piston in the hole.
The guide rod of mechanism of jumping a queue is corresponding one by one with rubber piston, and the diameter of the guide rod of jumping a queue can directly stretch in this hole, and can depress rubber piston less than the diameter in hole on the plug frock plate.
Closing the door of casing then, and locking, owing to be provided with sealing member between the door of casing and the box side, can make to be in the casing in the closed environment.Sealing member can be a rubber seal.The work of controller control vacuum generator makes to be in vacuum environment in the casing, and the negative pressure that reaches capacity of the air pressure in the casing, thereby the air of the soup bottom in the glass syringe is all discharged, and reaches the no bubble in enclosed liquid the inside.
Controller control cylinder piston rod is descending, promote subplate with the base plate of jumping a queue along guide upright post to lower slider, drive the guide rod of jumping a queue and press down with rubber piston and contact; Promote rubber piston and get in the glass syringe, by controller control downstream rate and downstream position, when the lower surface of rubber piston just with the glass syringe in soup upper surface when contacting; It is descending to stop cylinder piston, and to change service direction be up, drives the guide rod of jumping a queue and recovers initial position; One-period is accomplished, and opens cabinet door, takes out the glass syringe that has placed rubber piston; Push rod is screwed in the rubber piston, and encapsulation gets final product.
The vacuum stopper-adding machine that the present invention is used comprises the leak free casing, casing be provided with one can folding door; The side plate contact position of door and casing is provided with sealing member; The sidewall of middle and lower part is provided with the positioning tool plate in the said casing, and positioning tool plate top is provided with the mechanism that jumps a queue, and the casing side is provided with an interface that links to each other with the external vacuum producer; And interface communicates with box house, and the said mechanism that jumps a queue all links to each other with controller through lead with vacuum generator.Door is transparent translation door or transparent clamshell doors.The positioning tool plate is on the sidewall that is horizontally placed in the casing, and is respectively equipped with the two-stage positioning groove that matches with glass syringe frock plate that holds the glass syringe syringe and the plug locating plate of placing rubber piston on the positioning tool plate.The mechanism that jumps a queue comprises cylinder and two parallel guide upright posts on the top board that is fixed in casing; Said cylinder is positioned at the casing outside; Two parallel guide upright posts are positioned at box house; The piston rod of cylinder stretches in the casing, piston-rod end be enclosed within guide upright post on and can link to each other along its adding device that moves up and down.Adding device comprises the subplate of captiveing joint with piston-rod end, and the both sides of said subplate are enclosed within on the guide upright post respectively, and subplate is captiveed joint with the slip cap on being enclosed within guide upright post; Said subplate bottom links to each other with the base plate of jumping a queue through attaching parts, and the said base plate both sides of jumping a queue also are enclosed within respectively on the guide upright post, and the base plate bottom of jumping a queue is provided with some guide rods of jumping a queue that laterally arrange.Subplate laterally arranges with the base plate of jumping a queue.Attaching parts is a thru-bolt, and the two ends of thru-bolt are individually fixed in subplate and jump a queue on the base plate.Some guide rods of jumping a queue are corresponding with the rubber piston that its underpart need be handled respectively.Controller is industrial computer or micro controller system or PLC.
The invention has the beneficial effects as follows that the present invention adopts technique scheme, the air of glass syringe herb liquid bottom is all discharged, avoid soup to overflow, the plug lower edge that links to each other with push rod in the syringe just in time contacts with the soup upper surface.When medical personnel located either is used, unpack, install syringe needle; Promoting push rod can directly use, and need not worry to contain air bubble problem inside the soup again, has practiced thrift the time; Improved work efficiency, it is safe in utilization to have promoted soup, suitable long-distance transport and long-time storage.
Description of drawings
Fig. 1 is structural representation of the present invention (door opening state);
Fig. 2 is a lateral plan of the present invention;
1. casings wherein, 2. sealing member, 3., 4. interface, 5. cylinder, 6. guide upright post; 7. power seat, 8. slip cap, 9. subplate, the base plate of 10. jumping a queue, 11. guide rods of jumping a queue, 12. rubber pistons; 13. plug frock plate, 14. positioning tool plates, 15. glass syringe frock plates, 16. glass syringes, 17. seal caps.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is further specified.
Workflow of the present invention is: dress liquid product frock plate cartonning-tool locating-add plug frock plate location-cabinet door seal-vacuumizes-eliminates soup bubble-release of pressure completion product of jumping a queue-take out.The detailed operation flow process is following:
After placing the glass syringe frock plate 15 that occupies combination glass syringe; Be positioned over glass syringe frock plate 15 tops to the plug frock plate 13 that occupies rubber piston 12 again; And the part edge that makes plug frock plate 13 is stuck in another grade locating groove of positioning tool plate 14; The rubber piston 12 that can make plug frock plate 13 and wherein place keeps stability preferably when work disposal; And rubber piston 12 and combination glass syringe are aligned, help improving crudy, promote product quality.Rubber piston 12 quantity equate that with combination glass syringe quantity each rubber piston 12 is corresponding up and down with each combination glass syringe.Plug frock plate 13 also is a slab construction, which is provided with some holes, places rubber piston 12 in the hole.
The guide rod 11 of mechanism of jumping a queue is corresponding one by one with rubber piston 12, and the diameter of the guide rod 11 of jumping a queue can directly stretch in this hole less than the diameter in hole on the plug frock plate 13, and can depress rubber piston 12.
Closing the door 3 of casing 1 then, and locking, owing to be provided with sealing member 2 between the door 3 of casing 1 and the box side, can make to be in the casing 1 in the closed environment.Sealing member 2 can be a rubber seal.The work of controller control vacuum generator makes in the casing 1 to be in vacuum environment, and the negative pressure that reaches capacity of the air pressure in the casing 1, thereby the air of the soup bottom in the glass syringe is all discharged, and reaches the no bubble in enclosed liquid the inside.
Controller control cylinder piston rod is descending, promote subplate 9 with the base plate 10 of jumping a queue along guide upright post 6 to lower slider, drive the guide rod 11 of jumping a queue and press down with rubber piston 12 and contact; Promote rubber piston 12 and get in the glass syringes, by controller control downstream rate and downstream position, when the lower surface of rubber piston 12 just with the glass syringe in soup upper surface when contacting; It is descending to stop cylinder piston, and to change service direction be up, drives the guide rod 11 of jumping a queue and recovers initial positions; One-period is accomplished, and opens cabinet door 3, takes out the glass syringe that has placed rubber piston 12; Push rod is screwed in the rubber piston 12, and encapsulation gets final product.
When medical personnel located either is used, unpack, install syringe needle; Promoting push rod can directly use, and need not worry to contain air bubble problem inside the soup again, has practiced thrift the time; Improved work efficiency, it is safe in utilization to have promoted soup, suitable long-distance transport and long-time storage.
The vacuum stopper-adding machine that the present invention adopted like Fig. 1, shown in 2, comprises leak free casing 1, casing 1 be provided with one can folding door 3, door 3 is transparent translation door or transparent clamshell doors.The side plate contact position of door 3 and casing 1 is provided with sealing member 2; The sidewall of middle and lower part is provided with positioning tool plate 14 in the said casing 1; Positioning tool plate 14 tops are provided with the mechanism that jumps a queue; Casing 1 side is provided with an interface 4 that links to each other with the external vacuum producer, and interface 4 communicates with casing 1 inside, and the said mechanism that jumps a queue all links to each other with controller through lead with vacuum generator.Controller is industrial computer or micro controller system or PLC.
The mechanism that jumps a queue comprises the parallel guide upright post 6 with two of cylinder 5 on the top board that is fixed in casing 1; Said cylinder 5 is positioned at casing 1 outside; Two parallel guide upright posts 6 are positioned at casing 1 inside; The piston rod of cylinder 5 stretches in the casing 1, piston-rod end be enclosed within guide upright post 6 on and can link to each other along its adding device that moves up and down.Adding device comprises the subplate 9 of captiveing joint through power seat 7 with piston-rod end, and the both sides of subplate 9 are enclosed within respectively on the guide upright post 6, and subplate 9 is captiveed joint with the slip cap 8 on being enclosed within guide upright post 6; Subplate 9 bottoms link to each other with the base plate 10 of jumping a queue through attaching parts, and base plate 10 both sides of jumping a queue also are enclosed within respectively on the guide upright post 6, and base plate 10 bottoms of jumping a queue are provided with some guide rods 11 of jumping a queue that laterally arrange.Subplate 9 laterally arranges with the base plate 10 of jumping a queue.Attaching parts is a thru-bolt, and the two ends of thru-bolt are individually fixed on the subplate 9 and the base plate 10 of jumping a queue.Some guide rods 11 of jumping a queue are corresponding with the rubber piston 12 that its underpart need be handled respectively.
Though the above-mentioned accompanying drawing specific embodiments of the invention that combines is described; But be not restriction to protection domain of the present invention; One of ordinary skill in the art should be understood that; On the basis of technical scheme of the present invention, those skilled in the art need not pay various modifications that creative work can make or distortion still in protection scope of the present invention.
Claims (1)
1. a preparatory embedding glass syringe vacuum adds blocking method, it is characterized in that step is following:
1) dress liquid product frock plate cartonning; Seal cap is combined in glass syringe front end forms combination glass syringe, will make up the glass needle wound packages again and go in the hole of glass syringe frock plate, and in making up the glass syringe liquid drug; Door on the casing is opened, and the glass syringe frock plate that will occupy combination glass syringe again is positioned on the positioning tool plate in the casing;
2) tool locating; The part edge of glass syringe frock plate is stuck in the wherein one-level locating groove of positioning tool plate;
3) add plug frock plate location; Be positioned over glass syringe frock plate top to the plug frock plate that occupies rubber piston, and the part edge of plug frock plate is stuck in another grade locating groove of positioning tool plate;
4) cabinet door sealing, and locking owing to be provided with sealing member between the door of casing and the box side, can make to be in the casing in the closed environment;
5) vacuumize, eliminate the soup bubble; The work of controller control vacuum generator makes to be in vacuum environment in the casing, and the negative pressure that reaches capacity of the air pressure in the casing, thereby the air of the soup bottom in the glass syringe is all discharged, and reaches the no bubble in enclosed liquid the inside;
6) release of pressure is jumped a queue; Controller control cylinder piston rod is descending, promote subplate with the base plate of jumping a queue along guide upright post to lower slider, drive the guide rod of jumping a queue and press down with rubber piston and contact; Promote rubber piston and get in the glass syringe, by controller control downstream rate and downstream position, when the lower surface of rubber piston just with the glass syringe in soup upper surface when contacting; It is descending to stop cylinder piston; And to change service direction be up, drives the guide rod of jumping a queue and recover initial position, and one-period is accomplished;
7) open cabinet door, take out the glass syringe that has placed rubber piston, push rod is screwed in the rubber piston, encapsulation gets final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210374264.4A CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210374264.4A CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102838063A true CN102838063A (en) | 2012-12-26 |
| CN102838063B CN102838063B (en) | 2014-06-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210374264.4A Expired - Fee Related CN102838063B (en) | 2012-09-29 | 2012-09-29 | Pre-encapsulating glass syringe vacuum plugging method |
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| Country | Link |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103832961A (en) * | 2014-02-20 | 2014-06-04 | 温州市吉诺机械有限公司 | Syringe loading vacuum-pumping and plugging all-in-one machine |
| CN104229188A (en) * | 2014-08-28 | 2014-12-24 | 上海新亚药业有限公司 | Gradient-method vacuumizing process and device for full-pressure-plug antibiotics bottle |
| CN108423207A (en) * | 2018-03-28 | 2018-08-21 | 上海亚力机械科技有限公司 | The pre- filling apparatus of syringe |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH0656196A (en) * | 1992-08-03 | 1994-03-01 | Akiyuretsukusu:Kk | Vacuum internal capping machine |
| CN2795181Y (en) * | 2005-01-17 | 2006-07-12 | 中山博泰药械有限公司 | Medicine bottle pressurizing and sealing device |
| CN201358164Y (en) * | 2009-01-19 | 2009-12-09 | 湖南科伦制药有限公司 | Novel air-charging stopper-adding equipment |
| CN202007111U (en) * | 2011-03-31 | 2011-10-12 | 山东滨州博莱威生物技术有限公司 | High-speed rectilinear filling and plugging machine for preparing animal vaccines |
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2012
- 2012-09-29 CN CN201210374264.4A patent/CN102838063B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0656196A (en) * | 1992-08-03 | 1994-03-01 | Akiyuretsukusu:Kk | Vacuum internal capping machine |
| CN2795181Y (en) * | 2005-01-17 | 2006-07-12 | 中山博泰药械有限公司 | Medicine bottle pressurizing and sealing device |
| CN201358164Y (en) * | 2009-01-19 | 2009-12-09 | 湖南科伦制药有限公司 | Novel air-charging stopper-adding equipment |
| CN202007111U (en) * | 2011-03-31 | 2011-10-12 | 山东滨州博莱威生物技术有限公司 | High-speed rectilinear filling and plugging machine for preparing animal vaccines |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103832961A (en) * | 2014-02-20 | 2014-06-04 | 温州市吉诺机械有限公司 | Syringe loading vacuum-pumping and plugging all-in-one machine |
| CN103832961B (en) * | 2014-02-20 | 2015-12-30 | 温州市吉诺机械有限公司 | The filling all-in-one that vacuumizes and jump a queue of syringe |
| CN104229188A (en) * | 2014-08-28 | 2014-12-24 | 上海新亚药业有限公司 | Gradient-method vacuumizing process and device for full-pressure-plug antibiotics bottle |
| CN104229188B (en) * | 2014-08-28 | 2016-08-17 | 上海上药新亚药业有限公司 | A kind of total head plug antibiotic bottle gradient method evacuation process and device |
| CN108423207A (en) * | 2018-03-28 | 2018-08-21 | 上海亚力机械科技有限公司 | The pre- filling apparatus of syringe |
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| Publication number | Publication date |
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| CN102838063B (en) | 2014-06-04 |
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