CN102836393B - Medicament for treating chronic nephritis through permeation and kidney-activating cell regeneration therapy - Google Patents
Medicament for treating chronic nephritis through permeation and kidney-activating cell regeneration therapy Download PDFInfo
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- CN102836393B CN102836393B CN201210388926.3A CN201210388926A CN102836393B CN 102836393 B CN102836393 B CN 102836393B CN 201210388926 A CN201210388926 A CN 201210388926A CN 102836393 B CN102836393 B CN 102836393B
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Abstract
The invention relates to a medicament for treating chronic nephritis through a permeation and kidney-activating cell regeneration therapy. The medicament is prepared by uniformly mixing sixteen types of bulk pharmaceuticals including Chinese eaglewood, pseudo-ginseng root, honeysuckle flower, coptis root, prepared multiflower knotweed tuber, charred cortex eucommiae, pawpaw, safflower, sweet wormwood herb, heartleaf houttuynia herb, buffalo horn, common fennel, garden balsam stem, common andrographis herb, clove and turmeric, and extracting in an ultrasonic extraction way. The medicament is used by adopting a whole body medicated bath way, so that damages to the normal physiological functions of liver and kidney caused by the burden of taking of a large quantity of medicaments on liver and kidney are avoided, the peak valley phenomenon of the medicament concentration in blood is avoided, the normal blood concentration is maintained, a long residual action of a predicted curative effect is provided, the administration times are reduced, and the toxicity and untoward effect of the medicament are reduced. The medicament has the effects of treating an internal illness by external treatment, treating both principal and secondary aspects of a disease and consolidating basis, and the aim of comprehensively adjusting various physiological functions of the kidney is fulfilled.
Description
Technical field
The medicine that the present invention relates to a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive, belongs to tcm field.
Background technology
Kidney is the main Excretory organ of people and higher mammal, and it filters the refuse in human body to decompose the rear urine that forms, external through ureter output.The major function of kidney, except excretion refuse, also comprises adjusting body fluid, secreting hormone, maintains the balance of Water-Electrolyte etc., and it makes human inner cell's surrounding remain constant, to ensure that metabolism normally carries out.
Chronic glomerulonephritis is called for short chronic nephritis, is one group of renal glomerular disease take albuminuria, hematuria, hypertension, edema, renal hypofunction as clinical characters, the one group of primary glomerulopathy being comprised of multiple different pathogeny, different pathological types.Chronic glomerulonephritis can betide any age.Clinical characters is that the course of disease is long, slower development, symptom can gently can weigh, and has asymptomatic urine examination anomalistic period more, then occurs edema, albuminuria, microscopic hematuria in various degree, can accompanied with hypertension and (or) azotemia, and carrying out property increases the weight of renal function injury.
Chronic glomerulonephritis is most significantly not uncomfortable at the onset initial stage, or only has the slight soreness of waist, lumbago, easily out in the cold, if postpone treatment or malpractice, the state of an illness will constantly be made progress, once develop into the later stage, usually develop into uremia, will body and society be caused to huge harm.During uremia, nitrogenous metabolite and other toxicants can not be discharged, and accumulate in vivo, can cause the pathological changes of multiple organs and system.Existing various renal insufficiency, uremia and Renal Failure Patients 1,300 ten thousand～2,000 ten thousand left and right in various degree of China, current more than 900 ten thousand uremic patients are by dialysis existence, and just with annual 8% speed, constantly increase, if carry out dialysis treatment, no matter do hemodialysis or peritoneal dialysis, annual cost needs 5～200,000.This is all white elephant for family and society.Even if chronic glomerulonephritis does not develop into uremia, also need long-term treatment, the state of an illness also often repeatedly, is also a huge spirit and financial burden to patient and family, its hazardness is apparent.
Chronic glomerulonephritis has been baffled countless nephropathy experts repeatedly to show effect, and also makes a lot of patients with chronic glomerulonephritis unbearably worried.
Summary of the invention
The technical problem to be solved in the present invention is for above deficiency, a kind of medicine of permeable nephrocyte regeneration therapy for treating chronic nephritis alive is provided, overcome the poor defect of therapeutic effect in prior art, adopt after medicine of the present invention, utilize the affinity interaction principle of body surface organization to water liquid, by physical action, the effective ingredient of medicine is made to human body Passive intake and acts on body, through metabolism, make effective ingredient enter kidney focus, accelerate the blood circulation of kidney, activation, repair impaired renal tissue cell, thereby reach the object of the various physiological functions of comprehensive adjusting recovery kidney, can allow nephrotic recover renal function, therapeutic effect is good.
For solving above technical problem, the present invention by the following technical solutions: a kind of medicine of permeable nephrocyte alive regeneration therapy for treating chronic nephritis, is characterized in that: the crude drug composition of described medicine is by weight:
4～8 parts, 2～3 parts of Lignum Aquilariae Resinatum, 8～12 parts of Radix Notoginseng, 8～12 parts of Flos Loniceraes, 4～5 parts of Rhizoma Coptidis, 6～10 parts of Radix Polygoni Multiflori Preparata, 6～10 parts of charred Cortex Eucommiaes, 6～10 parts of Fructus Chaenomeliss, 6～10 parts, Flos Carthami, 4～8 parts of Herba Artemisiae Annuaes, 4～8 parts of Herba Houttuyniae, 4～8 parts of Cornu Bubalis, 15～23 parts of Fructus Foeniculi, 4～8 parts of Herba speranskiae tuberculataes, 4～8 parts of Herba Andrographis, 4～6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
A kind of prioritization scheme, the crude drug composition of described medicine is by weight:
6 parts, 3 parts of Lignum Aquilariae Resinatum, 10 parts of Radix Notoginseng, 10 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 8 parts of Radix Polygoni Multiflori Preparata, 8 parts of charred Cortex Eucommiaes, 8 parts of Fructus Chaenomeliss, 8 parts, Flos Carthami, 6 parts of Herba Artemisiae Annuaes, 6 parts of Herba Houttuyniae, 6 parts of Cornu Bubalis, 20 parts of Fructus Foeniculi, 6 parts of Herba speranskiae tuberculataes, 6 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Another kind of prioritization scheme, the crude drug composition of described medicine is by weight:
4 parts, 2 parts of Lignum Aquilariae Resinatum, 12 parts of Radix Notoginseng, 11 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 6 parts of Radix Polygoni Multiflori Preparata, 10 parts of charred Cortex Eucommiaes, 9 parts of Fructus Chaenomeliss, 7 parts, Flos Carthami, 7 parts of Herba Artemisiae Annuaes, 5 parts of Herba Houttuyniae, 4 parts of Cornu Bubalis, 22 parts of Fructus Foeniculi, 8 parts of Herba speranskiae tuberculataes, 5 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Another prioritization scheme, the crude drug composition of described medicine is by weight:
8 parts, 3 parts of Lignum Aquilariae Resinatum, 11 parts of Radix Notoginseng, 12 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 7 parts of Radix Polygoni Multiflori Preparata, 9 parts of charred Cortex Eucommiaes, 7 parts of Fructus Chaenomeliss, 9 parts, Flos Carthami, 4 parts of Herba Artemisiae Annuaes, 7 parts of Herba Houttuyniae, 8 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 5 parts of Herba speranskiae tuberculataes, 7 parts of Herba Andrographis, 4 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Further prioritization scheme, the crude drug composition of described medicine is by weight:
5 parts, 3 parts of Lignum Aquilariae Resinatum, 8 parts of Radix Notoginseng, 9 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 10 parts of Radix Polygoni Multiflori Preparata, 6 parts of charred Cortex Eucommiaes, 6 parts of Fructus Chaenomeliss, 10 parts, Flos Carthami, 5 parts of Herba Artemisiae Annuaes, 4 parts of Herba Houttuyniae, 7 parts of Cornu Bubalis, 23 parts of Fructus Foeniculi, 4 parts of Herba speranskiae tuberculataes, 8 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Further prioritization scheme, the crude drug composition of described medicine is by weight:
7 parts, 3 parts of Lignum Aquilariae Resinatum, 9 parts of Radix Notoginseng, 8 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 9 parts of Radix Polygoni Multiflori Preparata, 7 parts of charred Cortex Eucommiaes, 10 parts of Fructus Chaenomeliss, 6 parts, Flos Carthami, 8 parts of Herba Artemisiae Annuaes, 8 parts of Herba Houttuyniae, 5 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 7 parts of Herba speranskiae tuberculataes, 4 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Further prioritization scheme, described medicine is got each crude drug according to above proportioning, utilizes the mode of ultrasonic extraction to extract acquisition after mix homogeneously.
In above raw material:
Lignum Aquilariae Resinatum acrid, bitter, warm, returns spleen, stomach, kidney, lung meridian, sending down the abnormal ascending QI warming middle-JIAO, and warming the kidney improving inspiration by invigorating kidney-QI, cures mainly QI rising in reverse order and pants, vomits singultus, abdominal distention, waist knee joint cold caused by deficiency, large intestine constipation due to insufficiency, urine qi stranguria, man's cold sperm.
Radix Notoginseng sweet in the mouth, micro-hardship, warm in nature, return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel, and can stop blooding, fall apart blood, analgesic therapy cure mainly to fall and flutter congestive edema, thoracic obstruction angor, lump in the abdomen, blood stasis amenorrhea, dysmenorrhea, the cloudy stomachache of the stasis of blood in puerperal, sore, carbuncle and painful swelling.
Sweet, the micro-bitter, acrid, cold of Flos Lonicerae, return lung, stomach, the heart, large intestine channel, heat-clearing and toxic substances removing, and wind-heat dissipating, for carbuncle furuncle, sore throat erysipelas, pyretic toxicity, dysentery, anemopyretic cold, pestilence heating.
Rhizoma Coptidis hardship, cold, nontoxic, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tell nosebleed, conjunctival congestion, have a toothache, quench one's thirst, carbuncle furuncle, external treatment eczema, eczema, auditory meatus are suppurated.
Radix Polygoni Multiflori Preparata is puckery, tepor, invigorating the liver and kidney, benefiting essence-blood, Radix Polygoni Multiflori Preparata is with the Radix Polygoni Multiflori drying after boiling by Radix Polygoni Multiflori and Semen sojae atricolor, the good medicine that is invigorating the liver and kidney simply, benefiting essence-blood, nourish heart and allay excitement, is mainly used in the diseases such as soreness of the waist and knees that treatment causes because deficiency of the liver and kindey, essence and blood lose, dizziness and blurred vision, palpitation and insomnia, early whitening of hair.
Charred Cortex Eucommiae is sweet, micro-pungent, warm, enter liver, kidney channel, invigorating the liver and kidney, bone and muscle strengthening, antiabortive, cure mainly that spinal column ache, limbs flaccidity are weak, seminal emission, spermatorrhea, Diarrhoea, asthenia, dribbling urination, uncontrolled urination are itched, frequent fetal movement, vaginal bleeding during pregnancy are wanted to fall, overabundance of amniotic fluid, habitual abortion, hypertension.
Fructus Chaenomelis property is put down, is slightly cold, and sweet in the mouth is returned liver, spleen channel, suppressing the hyperactive liver relaxing muscles and tendons, and stomach function regulating removing dampness, for arthralgia chiefly caused by damp pathogen contracture, the swollen pain of waist knee joint acid, vomit and diarrhoea convulsion, beriberi edema.
Flos Carthami is warm in nature, acrid in the mouth, and promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain swell and ache for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection.
Herba Artemisiae Annuae bitter, acrid, cold, return liver, gallbladder meridian, three warmers, kidney channel, clear deficiency-heat thoroughly, and removing heat from blood is except steaming, and except steaming, preventing the attack (or recurrence) of malaria, for pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.
Herba Houttuyniae cold nature, bitter in the mouth, return lung meridian, bladder, large intestine channel, heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome, cure mainly that the main lung abscess vomiting pus of pyretic stranguria, expectorant dyspnea of heat type are coughed, larynx Oh, hematodiarrhoea, carbuncle sore tumefacting virus, pyretic stranguria.
Cornu Bubali hardship is salty, cold, enters the heart, liver, spleen, stomach four warps, and heat clearing away, removing heat from blood, removing toxic substances, cure mainly calentura headache, high fever coma, macule, tell nosebleed, infantile convulsion, sore throat pharyngeal swelling.
Fructus Foeniculi acrid in the mouth, warm in nature, enters kidney, bladder, stomach warp, stimulating appetite, and the cold expelling of regulating the flow of vital energy, has supporing yang road, cures mainly cold in middle-JIAO, loss of appetite, nausea and vomiting, abdominal part cold type of pain, hernia pain, painful and swollen testis, stagnation of QI in spleen and stomach, distension and fullness in the abdomen and has a pain.
Herba speranskiae tuberculatae another name Herba Viciae Amoenae, sweetness and bitterness, temperature, wind-damp dispelling, invigorates blood circulation, relaxing muscles and tendons, pain relieving, cures mainly rheumatalgia, sprain and contusion wound, innominate toxic swelling, eczema scrotum.
Herba Andrographis bitter in the mouth, cold in nature, GUIXIN, lung, large intestine, urinary bladder channel, heat-clearing and toxic substances removing, removing heat from blood, detumescence, dampness, cures mainly cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Flos Caryophylli is sweet, pungent, hot greatly, warming the stomach, and the kidney warming, cures mainly cold syndrome of the stomach pain with distension, singultus, vomiting and diarrhoea, arthralgia pain, colic, halitosis, toothache.
Rhizoma Curcumae Longae is pungent, bitter, and temperature is returned spleen, Liver Channel, removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia, for the breast side of body twinge, amenorrhea, lump in the abdomen, rheumatism shoulder arm pain, tumbling and swelling.
The present invention adopts after above technical scheme, compared with prior art, have the following advantages: utilize the affinity interaction principle of body surface organization to water liquid, utilize pharmacokinetics principle and the modern Chinese medicine transdermal dynamics technology of Chinese medicine, monarch, ministerial drug thing scientific composition, honor is ancient to be concocted, monarch drug is Lignum Aquilariae Resinatum, Radix Notoginseng, Flos Lonicerae and Rhizoma Coptidis, there is relaxing muscles and tendons to promote blood circulation, the effect of removing obstruction in the collateral to relieve pain, but its external efficacy is poor, therefore be equipped with ministerial drug as a supplement, ministerial drug is Radix Polygoni Multiflori Preparata, charred Cortex Eucommiae, Fructus Chaenomelis, Flos Carthami, Herba Artemisiae Annuae, Herba Houttuyniae, Cornu Bubali, Fructus Foeniculi, Herba speranskiae tuberculatae, Herba Andrographis, Flos Caryophylli and Rhizoma Curcumae Longae, its effective ingredient contains multiple natural short penetrating agent, can promptly see through human cuticular tissue makes monarch's the effective elements of the medicine directly penetrate into focus, by physical action, the effective elements of the medicine in above-mentioned ten Six-elements is made to human body Passive intake and acts on body, through metabolism, make effective ingredient enter kidney focus, accelerate the blood circulation of kidney, activation, repair impaired renal tissue cell, thereby reach the object for the treatment of, its particular advantages is to avoid long-term a large amount of drug administration to produce burden and the normal physiological function of destruction Liver and kidney to Liver and kidney, avoid the peak valley phenomenon of blood Chinese medicine concentration, maintain normal blood drug level, the long-lasting of expected effect is provided, reduce medication number of times, reduce toxicity and the untoward reaction of medicine, inner disease outer treat, treating both the principal and secondary aspects of a disease, vital base and primordial QI consolidating, thereby reach the object of the various physiological functions of comprehensive adjusting recovery kidney.
Below in conjunction with embodiment, the present invention is described in detail.
The specific embodiment
Embodiment 1, a medicine for permeable nephrocyte alive regeneration therapy for treating chronic nephritis, comprises 6 parts, 3 parts of Lignum Aquilariae Resinatum, 10 parts of Radix Notoginseng, 10 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 8 parts of Radix Polygoni Multiflori Preparata, 8 parts of charred Cortex Eucommiaes, 8 parts of Fructus Chaenomeliss, 8 parts, Flos Carthami, 6 parts of Herba Artemisiae Annuaes, 6 parts of Herba Houttuyniae, 6 parts of Cornu Bubalis, 20 parts of Fructus Foeniculi, 6 parts of Herba speranskiae tuberculataes, 6 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Embodiment 2, a medicine for permeable nephrocyte alive regeneration therapy for treating chronic nephritis, comprises 4 parts, 2 parts of Lignum Aquilariae Resinatum, 12 parts of Radix Notoginseng, 11 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 6 parts of Radix Polygoni Multiflori Preparata, 10 parts of charred Cortex Eucommiaes, 9 parts of Fructus Chaenomeliss, 7 parts, Flos Carthami, 7 parts of Herba Artemisiae Annuaes, 5 parts of Herba Houttuyniae, 4 parts of Cornu Bubalis, 22 parts of Fructus Foeniculi, 8 parts of Herba speranskiae tuberculataes, 5 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Embodiment 3, a medicine for permeable nephrocyte alive regeneration therapy for treating chronic nephritis, comprises 8 parts, 3 parts of Lignum Aquilariae Resinatum, 11 parts of Radix Notoginseng, 12 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 7 parts of Radix Polygoni Multiflori Preparata, 9 parts of charred Cortex Eucommiaes, 7 parts of Fructus Chaenomeliss, 9 parts, Flos Carthami, 4 parts of Herba Artemisiae Annuaes, 7 parts of Herba Houttuyniae, 8 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 5 parts of Herba speranskiae tuberculataes, 7 parts of Herba Andrographis, 4 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Embodiment 4, a medicine for permeable nephrocyte alive regeneration therapy for treating chronic nephritis, comprises 5 parts, 3 parts of Lignum Aquilariae Resinatum, 8 parts of Radix Notoginseng, 9 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 10 parts of Radix Polygoni Multiflori Preparata, 6 parts of charred Cortex Eucommiaes, 6 parts of Fructus Chaenomeliss, 10 parts, Flos Carthami, 5 parts of Herba Artemisiae Annuaes, 4 parts of Herba Houttuyniae, 7 parts of Cornu Bubalis, 23 parts of Fructus Foeniculi, 4 parts of Herba speranskiae tuberculataes, 8 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
Embodiment 5, a medicine for permeable nephrocyte alive regeneration therapy for treating chronic nephritis, comprises 7 parts, 3 parts of Lignum Aquilariae Resinatum, 9 parts of Radix Notoginseng, 8 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 9 parts of Radix Polygoni Multiflori Preparata, 7 parts of charred Cortex Eucommiaes, 10 parts of Fructus Chaenomeliss, 6 parts, Flos Carthami, 8 parts of Herba Artemisiae Annuaes, 8 parts of Herba Houttuyniae, 5 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 7 parts of Herba speranskiae tuberculataes, 4 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
According to measuring crude drug dividing in above-mentioned five embodiment, after mix homogeneously, utilize the mode of ultrasonic extraction to extract acquisition, the mechanism of ultrasonic extraction comprises mechanical mechanism, calorifics mechanism and cavitation mechanism, when a large amount of ul-trasonic irradiations is when extracting medium, when shaking in rarefaction state, medium is torn into a lot of holes, these little holes again moment closure, when closed, produce the instantaneous pressure up to several kilo-atmospheric pressures, the cell wall of extract and the moment of breaking of whole organism are completed, advantage is that extraction ratio is high, extraction time is short, and keep to greatest extent the activity of extract effective ingredient and utilization rate and by its effective ingredient separation and purification, obtain 1 part of medicine.
Using method: whole body dipping: above-mentioned 1 part of medicine is placed in to the warm water of 5000 parts 38 ℃～42 ℃, fully dissolves, mix homogeneously, then ducks in drink health 1 hour, and once, ten dippings are as a course for the treatment of in dipping in three days.
Contrast test: choose 600 routine patients with chronic glomerulonephritis, choose at random 500 examples as treatment group, other 100 examples as a control group, wherein 500 routine patients are divided into treatment group 1, treatment group 2, treatment group 3, treatment group 4 and treatment group 5, each treatment group is treated the 100 routine patients that choose at random, treatment group 1 is used medicine prepared by the embodiment of the present invention 1 to carry out whole body dipping, treatment group 2 is used medicine prepared by the embodiment of the present invention 2 to carry out whole body dipping, treatment group 3 is used medicine prepared by the embodiment of the present invention 3 to carry out whole body dipping, treatment group 4 is used medicine prepared by the embodiment of the present invention 4 to carry out whole body dipping, treatment group 5 is used medicine prepared by the embodiment of the present invention 5 to carry out whole body dipping, 1 part of medicine is placed in to the warm water of 5000 parts 38 ℃～42 ℃, fully dissolve, mix homogeneously, then health is ducked in drink 1 hour, dipping in three days once, ten dippings are as a course for the treatment of.
Matched group is according to conventional Therapeutic Method, the oral cooperation Astragalus Injection in Treating of prednisone, meticortelone and cyclophosphamide.
Detect the variation of routine blood test, urinalysis, 2～4 hours Urinary microproteins.
Therapeutic outcome after course for the treatment of contrast situation is as following table:
| Contrast group | Effective (example) | Effectively (example) | Invalid (example) | Total effective rate |
| Treatment group 1 | 75 | 20 | 5 | 95% |
| Treatment group 2 | 70 | 18 | 12 | 88% |
| Treatment group 3 | 72 | 19 | 9 | 91% |
| Treatment group 4 | 68 | 22 | 10 | 90% |
| Treatment group 5 | 70 | 19 | 11 | 89% |
| Matched group | 56 | 23 | 21 | 79% |
As can be seen from the above data, the Drug therapy chronic nephritis of using five embodiment of the present invention to prepare, the effective percentage of medicine prepared by five embodiment of the present invention is all high than the effective percentage of matched group conventional therapy, and average effectiveness level reaches 90.6%, and wherein the effect of embodiment 1 is best; Continual cure reaches 93.4% after three courses for the treatment of.
The mechanism of action of medicine of the present invention is to utilize the affinity interaction principle of body surface organization to water liquid, by physical action, the effective ingredient of above-mentioned ten six medicaments is made to human body Passive intake and acts on body, through metabolism, make effective ingredient enter kidney focus, accelerate the blood circulation of kidney, activation, repairs impaired renal tissue cell, thereby reaches the object of the various physiological functions of comprehensive adjusting recovery kidney.
The above is giving an example of best mode for carrying out the invention, and the part of wherein not addressing is in detail those of ordinary skills' common practise.Protection scope of the present invention is as the criterion with the content of claim, and any equivalent substitution carrying out based on technology enlightenment of the present invention, also within protection scope of the present invention.
Claims (7)
1. a medicine for permeable nephrocyte regeneration therapy for treating chronic nephritis alive, is characterized in that: the crude drug composition of described medicine is by weight:
4～8 parts, 2～3 parts of Lignum Aquilariae Resinatum, 8～12 parts of Radix Notoginseng, 8～12 parts of Flos Loniceraes, 4～5 parts of Rhizoma Coptidis, 6～10 parts of Radix Polygoni Multiflori Preparata, 6～10 parts of charred Cortex Eucommiaes, 6～10 parts of Fructus Chaenomeliss, 6～10 parts, Flos Carthami, 4～8 parts of Herba Artemisiae Annuaes, 4～8 parts of Herba Houttuyniae, 4～8 parts of Cornu Bubalis, 15～23 parts of Fructus Foeniculi, 4～8 parts of Herba speranskiae tuberculataes, 4～8 parts of Herba Andrographis, 4～6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
2. the medicine of a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive as claimed in claim 1, is characterized in that: the crude drug composition of described medicine is by weight:
6 parts, 3 parts of Lignum Aquilariae Resinatum, 10 parts of Radix Notoginseng, 10 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 8 parts of Radix Polygoni Multiflori Preparata, 8 parts of charred Cortex Eucommiaes, 8 parts of Fructus Chaenomeliss, 8 parts, Flos Carthami, 6 parts of Herba Artemisiae Annuaes, 6 parts of Herba Houttuyniae, 6 parts of Cornu Bubalis, 20 parts of Fructus Foeniculi, 6 parts of Herba speranskiae tuberculataes, 6 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
3. the medicine of a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive as claimed in claim 1, is characterized in that: the crude drug composition of described medicine is by weight:
4 parts, 2 parts of Lignum Aquilariae Resinatum, 12 parts of Radix Notoginseng, 11 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 6 parts of Radix Polygoni Multiflori Preparata, 10 parts of charred Cortex Eucommiaes, 9 parts of Fructus Chaenomeliss, 7 parts, Flos Carthami, 7 parts of Herba Artemisiae Annuaes, 5 parts of Herba Houttuyniae, 4 parts of Cornu Bubalis, 22 parts of Fructus Foeniculi, 8 parts of Herba speranskiae tuberculataes, 5 parts of Herba Andrographis, 6 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
4. the medicine of a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive as claimed in claim 1, is characterized in that: the crude drug composition of described medicine is by weight:
8 parts, 3 parts of Lignum Aquilariae Resinatum, 11 parts of Radix Notoginseng, 12 parts of Flos Loniceraes, 4 parts of Rhizoma Coptidis, 7 parts of Radix Polygoni Multiflori Preparata, 9 parts of charred Cortex Eucommiaes, 7 parts of Fructus Chaenomeliss, 9 parts, Flos Carthami, 4 parts of Herba Artemisiae Annuaes, 7 parts of Herba Houttuyniae, 8 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 5 parts of Herba speranskiae tuberculataes, 7 parts of Herba Andrographis, 4 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
5. the medicine of a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive as claimed in claim 1, is characterized in that: the crude drug composition of described medicine is by weight:
5 parts, 3 parts of Lignum Aquilariae Resinatum, 8 parts of Radix Notoginseng, 9 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 10 parts of Radix Polygoni Multiflori Preparata, 6 parts of charred Cortex Eucommiaes, 6 parts of Fructus Chaenomeliss, 10 parts, Flos Carthami, 5 parts of Herba Artemisiae Annuaes, 4 parts of Herba Houttuyniae, 7 parts of Cornu Bubalis, 23 parts of Fructus Foeniculi, 4 parts of Herba speranskiae tuberculataes, 8 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
6. the medicine of a kind of permeable nephrocyte regeneration therapy for treating chronic nephritis alive as claimed in claim 1, is characterized in that: the crude drug composition of described medicine is by weight:
7 parts, 3 parts of Lignum Aquilariae Resinatum, 9 parts of Radix Notoginseng, 8 parts of Flos Loniceraes, 5 parts of Rhizoma Coptidis, 9 parts of Radix Polygoni Multiflori Preparata, 7 parts of charred Cortex Eucommiaes, 10 parts of Fructus Chaenomeliss, 6 parts, Flos Carthami, 8 parts of Herba Artemisiae Annuaes, 8 parts of Herba Houttuyniae, 5 parts of Cornu Bubalis, 15 parts of Fructus Foeniculi, 7 parts of Herba speranskiae tuberculataes, 4 parts of Herba Andrographis, 5 parts of Flos Caryophyllis and Rhizoma Curcumae Longae.
7. as the medicine of a kind of permeable alive nephrocyte regeneration therapy for treating chronic nephritis of claim 1-6 as described in one of them, it is characterized in that: described medicine is got each crude drug according to above proportioning, after mix homogeneously, utilize the mode of ultrasonic extraction to extract acquisition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210388926.3A CN102836393B (en) | 2012-10-15 | 2012-10-15 | Medicament for treating chronic nephritis through permeation and kidney-activating cell regeneration therapy |
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| CN1222365A (en) * | 1998-01-08 | 1999-07-14 | 董汉杰 | Chinese medicine for curing nephrasthenia and its preparation |
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| CN1222365A (en) * | 1998-01-08 | 1999-07-14 | 董汉杰 | Chinese medicine for curing nephrasthenia and its preparation |
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| Title |
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| 南京中医药大学.沉香等.《中药大辞典》.2006,第1630、2641等页. * |
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