CN102836032A - Corneal trephine - Google Patents

Corneal trephine Download PDF

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Publication number
CN102836032A
CN102836032A CN201210319915XA CN201210319915A CN102836032A CN 102836032 A CN102836032 A CN 102836032A CN 201210319915X A CN201210319915X A CN 201210319915XA CN 201210319915 A CN201210319915 A CN 201210319915A CN 102836032 A CN102836032 A CN 102836032A
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China
Prior art keywords
base
tumbler
corneal
corneal trephine
trephine
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Pending
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CN201210319915XA
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Chinese (zh)
Inventor
许永根
肖真
洪晶
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Peking University Third Hospital
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Peking University Third Hospital
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Publication date
Application filed by Peking University Third Hospital filed Critical Peking University Third Hospital
Priority to CN201210319915XA priority Critical patent/CN102836032A/en
Publication of CN102836032A publication Critical patent/CN102836032A/en
Pending legal-status Critical Current

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Abstract

The invention provides a corneal trephine comprising a Y-shaped handle, a base, a rotating piece and a tool bit. The Y-shaped handle comprises a hand-held portion and a pair of fork fingers. The base takes the shape of a hollow circular cylinder. The outer side surface of the base is combined with the pair of the fork fingers of the Y-shaped handle, so the base can rotate around the connection line between ends of the pair of the fork fingers as a shaft. The rotating piece takes the shape of a hollow circular cylinder. The upper end of the rotating piece is provided with an extension portion extending transversely. The rotating piece is rotatably inserted in the base, and the extension portion on the upper end of the rotating piece is supported on the upper end portion of the base. The tool bit is fixed on the lower end of the rotating piece, and is exposed out of the lower end surface of the base by the predetermined height. When the corneal trephine is used for performing the corneal transplantation operation, the corneal trephine is easily and fixedly fixed on the corneas of patients so as to prevent the corneal trephine shifting or falling off in the operation, and the proper pressure is easily applied onto the corneal trephine, and the maximum depth of cut is ensured, so the operation is more safe and accurate.

Description

A kind of corneal trephine
Technical field
The present invention relates to the surgical clinical medical apparatus and instruments, specifically, relate to a kind of corneal trephine.
Background technology
Blinding property keratopathy becomes the world today's three big blinding property oculopathy with diabetic retinopathy, glaucoma.Blinding property keratopathy is many by due to infectious keratitis, cerneal dystrophy, corneal degeneration or the cornea wound.The unique method that at present, blinding property keratopathy patient is recovered lost eyesight is to carry out corneal graft.According to statistics, ten thousand blinding property keratopathy patients surplus China has 150 now, but because the source of cornea donor is very limited, the patient that can accept corneal graft every year has only about 10,000.Therefore, improve cornea donor survival rate, to improve corneal graft, reduce post-operative complication in the art be vital for the success of corneal graft.
In corneal graft, be operation the most key in the whole surgery with the process of corneal trephine ring cutting patient cornea.Fig. 1 is the schematic perspective view of ring cutting patient cornea in the corneal graft, and Fig. 2 is the generalized section of ring cutting patient cornea in the corneal graft.As depicted in figs. 1 and 2, eyeball is made up of wall of eyeball and eyeball content, and the outermost layer of wall of eyeball is made up of cornea 1 and sclera 2, and wherein, preceding 1/6 is transparent cornea 1, and back 5/6 is milky sclera 2.The rear of cornea 1 is iris 3 and crystalline lens 4, between cornea 1 and iris 3, has formed anterior chamber 5, has been full of aqueous humor among the anterior chamber 5.In corneal graft, at first to carry out the ring cutting excision with 6 couples of patients' of corneal trephine cornea 1, and then normal cornea donor is transplanted on patient's the eyeball.
Fig. 3 shows the side view of a kind of corneal trephine of present use.As shown in Figure 3, the structure of existing corneal trephine 6 is fairly simple, comprises body 7 and cutter portion 8; Wherein, Body 7 is hollow cylindrical, and cutter portion 8 is also approximate to be hollow cylindrical, but the thickness of its post jamb reduces from top to bottom gradually and form the edge of a knife that can carry out ring cutting bottom at post jamb.The upper end of the lower end of body 7 and cutter portion 8 is fixed together, and the central axes of the central axis of body 7 and cutter portion 8.
When using 6 pairs of patient's corneas of existing corneal trephine to carry out ring cutting; The edge of a knife with corneal trephine 6 places on patient's cornea earlier; Use the upper end of the body 7 of a have gentle hands light press corneal trephine 6 then; With the lateral surface of another hands contact body 7 rotating corneal trephine 6, thereby make corneal trephine 6 cut patient's cornea.Can know from top description, when using this corneal trephine 6, through pressing the upper end of the hollow cylindrical body 7 of corneal trephine 6 to fix corneal trephine 6 with light finger.If finger pressure is big, finger was just big with the friction of body 7 when body 7 rotated so, thereby the rotation of body 7 is difficult for; And if finger pressure is little, the feed of cutter portion 8 is just slow so, therefore; In operation, need to regulate the pressure of finger regularly; Like this, not finger corneal trepan 6 fixing just very not firm, and also it is wayward to be applied to the size and the uniformity of the pressure on the corneal trephine 6.This just usually cause corneal trephine 6 on patient's cornea displacement in addition come off; And the ring cutting degree of depth and the ring cutting uniformity of very difficult control corneal trephine 6; To such an extent as to it is suddenly local or integrally penetrate patient's cornea and damage iris and crystalline lens to occur the edge of a knife easily, for operation brings complication in the art.
Also has another kind of corneal trephine.This corneal trephine utilizes the vacuum suction ring to be fixed on patient's cornea, and rotates corneal trephine through hands and excise patient's cornea.Though this corneal trephine utilizes the vacuum suction ring to be fixed on patient's cornea; And can come ring cutting-in degree through the rotational angle of this corneal trephine; But its disadvantage is complicated operation, disposable use and costs an arm and a leg, increased patient's financial burden greatly.
Summary of the invention
The object of the present invention is to provide a kind of corneal trephine; Make when using this corneal trephine to carry out corneal graft; Can be easily and securely this corneal trephine be fixed on patient's the cornea to avoid this corneal trephine displacement in art, to occur or to break away from; Can easily on this corneal trephine, apply suitable pressure and guarantee the depth capacity of feed, thus make operation more safety with accurately.
To achieve these goals, the present invention provides a kind of corneal trephine, and this corneal trephine comprises: Y type handle, and this Y type handle comprises Handheld Division and a pair of interdigital; Base, this base is hollow cylindrical, a pair of interdigital combination of its lateral surface and said Y type handle, makes this base to rotate for axle by said a pair of interdigital finger tip line; Tumbler, this tumbler is hollow cylindrical, and its upper end is formed with the extension of horizontal extension, and this tumbler is inserted in the said base rotationally, and the extension of this tumbler upper end is supported on the upper end of said base; And cutter head, this cutter head is fixed on the lower end of said tumbler, and this cutter head exposes the predetermined height in said base lower surface.
In addition, the upper surface at the extension of said tumbler can also be provided with turning handle.
Preferably, the lower surface of the extension of the upper end of said base or said tumbler can be formed with annular groove.In one embodiment, the upper end of said base is formed with annular groove, and the lower surface of the extension of said tumbler is formed with annular protrusion, and said annular protrusion embeds in the said annular groove.In another embodiment, the lower surface of the extension of said tumbler is formed with annular groove, and the upper end of said base is formed with annular protrusion, and said annular protrusion embeds in the said annular groove.
The internal groove side wall of above-mentioned annular groove and external groove sidevall can have different height.
Can know according to top narration and practice; When using corneal trephine of the present invention to carry out corneal graft; With a Handheld Division that holds the Y type handle of this corneal trephine, thereby this corneal trephine cutter head is fixed on patient's the cornea down, rotates the tumbler of this corneal trephine with another hands (through turning handle); Thereby the cutter head of this corneal trephine is rotated, so that with patient's corneal ablation.Owing to hold this corneal trephine through handle, and again because the base of this corneal trephine can rotate around the interdigital finger tip line of handle, therefore, the lower surface of the base of this corneal trephine can be close to automatically on the cornea of heaving slightly.Like this, in whole surgery, just be easy to this corneal trephine is fixed on patient's the cornea and avoids this corneal trephine displacement in art, to occur or break away from.In addition, in the feed process, come the rotated part through turning handle; Therefore be easy on tumbler, apply suitable pressure; Particularly, because exposing the maximum height of base lower surface, is scheduled to cutter head, therefore; Can accurately control the depth capacity of feed, thereby make operation safety and accurate more.
In corneal trephine of the present invention, between the lower surface of the extension of the upper end of base and tumbler,, make that the contact area between tumbler and the base reduces, thereby the frictional force between tumbler and the base is reduced through concavo-convex combination design.This facilitates the rotation of tumbler with respect to base, thereby can more easily control the feed process.
Description of drawings
Fig. 1 is the schematic perspective view of ring cutting patient cornea in the corneal graft;
Fig. 2 is the generalized section of ring cutting patient cornea in the corneal graft;
Fig. 3 shows the side view of a kind of corneal trephine of present use;
Fig. 4 shows the perspective view of the described corneal trephine of one embodiment of the present of invention;
Fig. 5 shows the perspective view of the Y type handle in the described corneal trephine of one embodiment of the present of invention;
Fig. 6 shows a three-dimensional cutaway view of base, tumbler and cutter head assembly in the described corneal trephine of one embodiment of the present of invention;
Fig. 7 shows another three-dimensional cutaway view of base, tumbler and cutter head assembly in the described corneal trephine of one embodiment of the present of invention; And
Fig. 8 shows the three-dimensional view sub-anatomy of base, tumbler and cutter head assembly in the described corneal trephine of one embodiment of the present of invention.
Wherein, Reference numeral is:
1, cornea; 2, sclera; 3, iris; 4, crystalline lens; 5, anterior chamber;
6, existing corneal trephine; 7, body; 8, cutter portion;
100, corneal trephine of the present invention;
10, Y type hands handle; 11, Handheld Division; 12, interdigital;
20, base; 22, annular groove; 22a, internal groove side wall; 22b, external groove sidevall;
30, tumbler; 31, extension; 32, annular protrusion; 33, turning handle;
40, cutter head.
The specific embodiment
The embodiment of corneal trephine of the present invention is described below with reference to accompanying drawing.Obviously, under situation without departing from the spirit and scope of the present invention, can revise described embodiment with various mode.Therefore, accompanying drawing is illustrative with being described in essence, rather than is used to limit the protection domain of claim.In addition, in this manual, accompanying drawing is not in scale to be drawn.
Fig. 4 shows the perspective view of the described corneal trephine of one embodiment of the present of invention; Fig. 5 shows the perspective view of the Y type handle in this corneal trephine; Fig. 6 and Fig. 7 show the three-dimensional cutaway view of base, tumbler and cutter head assembly this corneal trephine from different angles, and Fig. 8 shows the three-dimensional view sub-anatomy of base, tumbler and cutter head assembly in this corneal trephine.Referring to Fig. 4-Fig. 8, the described corneal trephine 100 of one embodiment of the present of invention comprises Y type handle 10, base 20, tumbler 30 and cutter head 40.
As shown in Figure 5, Y type handle 10 comprises Handheld Division 11 and a pair of interdigital 12.
Shown in Fig. 6-8, base 20 is hollow cylindrical, and its lateral surface combines with a pair of interdigital 12 of Y type handle 10, makes base 20 to rotate for axle by said a pair of interdigital 12 finger tip line.Specifically, in the present embodiment, the lateral surface of base 20 is formed with a pair of transverse process, and this a pair of transverse process inserts respectively in the cavity of a pair of interdigital 12 finger tip of Y type handle 10, thereby base 20 can rotate with respect to a pair of interdigital 12 of Y type handle 10.In other embodiments, also can be, the lateral surface of base 20 be formed with a pair of cavity, and a pair of interdigital 12 finger tip of Y type handle 10 is formed with a pair of transverse process, thereby a pair of interdigital 12 of Y type handle 10 is combined with the lateral surface of base 20.
Tumbler 30 is hollow cylindrical, and its upper end is formed with the extension 31 of horizontal extension.Tumbler 30 is inserted in the base 20 rotationally, and the extension 31 of tumbler 30 upper ends is supported on the upper end of base 20.Cutter head 40 is fixed on the lower end of tumbler 30, and as shown in Figure 7, and cutter head 40 exposes the predetermined height in base 20 lower surfaces.In addition, for the purpose of rotated part 30 is convenient, can turning handle 33 be set at the upper surface of the extension 31 of tumbler 30.
When rotating and the frictional force between the base 20, can reduce the contact area between the upper end of extension 31 and base 20 of tumbler 30 in order to reduce tumbler 30.For this reason, shown in Fig. 6-8, can form annular groove 22 in the upper end of base 20.For the contact area between the upper end of the extension 31 that further reduces tumbler 30 and base 20; The internal groove side wall 22a and the external groove sidevall 22b of above-mentioned annular groove 22 can have different height, make to have only a cell wall to contact with the lower surface of the extension 31 of tumbler 30 among internal groove side wall 22a and the external groove sidevall 22b.Preferably, the lower surface of the extension 31 of tumbler 30 can be formed with annular protrusion 32, and annular protrusion 32 embeds in the said annular groove 22, but the best bottom land of contact ring connected in star 22 not of annular protrusion 32.Annular protrusion 32 and annular groove 22 combine not only can stiffener rings connected in star 22 structure, and can make tumbler 30 and base 20 combine more firmly, but do not increase frictional force between the two.
In other embodiment, also can be that the lower surface of the extension of said tumbler is formed with annular groove.Further, the internal groove side wall of this annular groove and external groove sidevall can have different height.In addition, the upper end of said base can also be formed with annular protrusion, and said annular protrusion embeds in the said annular groove.It is of equal value that structure in this structure configuration and the present embodiment is configured on the effect.
To combine Fig. 4-Fig. 8 to describe the method for using and the advantage thereof of corneal trephine of the present invention below.
When using corneal trephine 100 of the present invention to carry out corneal graft; With a Handheld Division 11 that holds the Y type handle 10 of corneal trephine 100; Thereby corneal trephine 100 cutter heads are fixed on patient's the cornea down; Rotate the tumbler 30 of corneal trephines 100 with the another hands through turning handle 33, thereby the cutter head 40 of corneal trephine 100 is rotated, so that with patient's corneal ablation.
Owing to hold corneal trephine 100 through handle 10; And again because the base 20 of corneal trephine 100 can be around the finger tip line rotation of handle interdigital 12; Therefore, the lower surface of the base 20 of corneal trephine 100 can automatically be close on the cornea of heaving slightly.Like this, in whole surgery, just be easy to corneal trephine 100 is fixed on patient's the cornea and avoids corneal trephine 100 displacement in art, to occur or break away from.In addition, when corneal trephine 100 had just placed on patient's cornea, because tumbler 30 is active with respect to base 20, therefore, cutter head 40 upwards was retracted in the cavity of base 20.In the feed process, come rotated part 30 and apply downward pressure to tumbler 30 through turning handle 33.Therefore be easy to the lower surface that on tumbler 30, applies suitable pressure and make cutter head 40 expose base 20 gradually, so that patient's cornea is cut.Be scheduled to because cutter head 40 exposes the maximum height of base 20 lower surfaces, therefore, can accurately control the depth capacity of feed, prevent that cutter head 40 from penetrating patient's cornea suddenly and damaging iris and crystalline lens, thereby make operation safety and accurate more.
In corneal trephine of the present invention; Between the lower surface of the extension 31 of the upper end of base 20 and tumbler 30; Through concavo-convex combination design, make that the contact area between tumbler 30 and the base 20 reduces, thereby the frictional force between tumbler 30 and the base 20 is reduced.This facilitates the rotation of tumbler 30 with respect to base 20, thereby can more easily control the feed process.
For the corneal trephine that the invention described above proposed, can also on the basis that does not break away from content of the present invention, make various improvement.Therefore, protection scope of the present invention should be confirmed by the content of appending claims.

Claims (6)

1. corneal trephine comprises:
Y type handle, this Y type handle comprises Handheld Division and a pair of interdigital;
Base, this base is hollow cylindrical, a pair of interdigital combination of its lateral surface and said Y type handle, makes this base to rotate for axle by said a pair of interdigital finger tip line;
Tumbler, this tumbler is hollow cylindrical, and its upper end is formed with the extension of horizontal extension, and this tumbler is inserted in the said base rotationally, and the extension of this tumbler upper end is supported on the upper end of said base; And
Cutter head, this cutter head is fixed on the lower end of said tumbler, and this cutter head exposes the predetermined height in said base lower surface.
2. corneal trephine as claimed in claim 1, wherein,
Upper surface at the extension of said tumbler is provided with turning handle.
3. corneal trephine as claimed in claim 1, wherein,
The lower surface of the upper end of said base or the extension of said tumbler is formed with annular groove.
4. corneal trephine as claimed in claim 3, wherein,
The upper end of said base is formed with annular groove, and the lower surface of the extension of said tumbler is formed with annular protrusion, and said annular protrusion embeds in the said annular groove.
5. corneal trephine as claimed in claim 3, wherein,
The lower surface of the extension of said tumbler is formed with annular groove, and the upper end of said base is formed with annular protrusion, and said annular protrusion embeds in the said annular groove.
6. like the described corneal trephine of arbitrary claim among the claim 3-5, wherein,
The internal groove side wall and the external groove sidevall of said annular groove have different height.
CN201210319915XA 2012-08-31 2012-08-31 Corneal trephine Pending CN102836032A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107028700A (en) * 2017-04-05 2017-08-11 青岛大学附属医院 Corneal epithelial flap former and corneal epithelial flap forming method
CN108186194A (en) * 2018-01-03 2018-06-22 沈阳何氏眼科医院有限公司 Ophthalmologic operation ultrasound knife
CN108578061A (en) * 2018-07-10 2018-09-28 上海市同济医院 A kind of limbal stem cell transplantation device
CN109106501A (en) * 2018-10-09 2019-01-01 北京航空航天大学 A kind of ophthalmologic operation ring cutting device with force sensing function

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1089824A (en) * 1993-01-19 1994-07-27 中国人民解放军军事医学科学院放射医学研究所 Cornea cutter
RU2158571C1 (en) * 1999-12-27 2000-11-10 ГУ МНТК "Микрохирургия глаза" Device for marking-out of uncisions of eye cornea at phacoemulsification of cataract on eye with miotic pupil
US6371966B1 (en) * 1998-09-30 2002-04-16 Becton, Dickinson And Company Corneal incision device
WO2003026542A1 (en) * 2001-09-21 2003-04-03 Geuder Ag Eye surgical instrument
CN2579388Y (en) * 2002-12-03 2003-10-15 赵广华 Corneal epithelium valve forming device
US6840947B2 (en) * 2000-10-12 2005-01-11 Moria Sa Device for surgery of the cornea
US20070083087A1 (en) * 2005-10-12 2007-04-12 Sismed, Llc Fixator with membrane
JP2007130334A (en) * 2005-11-11 2007-05-31 Kenji Yoshida Constant depth cornea loop incision apparatus
US20070129741A1 (en) * 2005-12-07 2007-06-07 Weston Philip D Artificial anterior chamber for use in keratoplasty
US20070185509A1 (en) * 2006-02-02 2007-08-09 Nidek Co., Ltd. Corneal incision apparatus and blade case for storing blade unit to be mounted in the corneal incision apparatus
CN202821802U (en) * 2012-08-31 2013-03-27 北京大学第三医院 Corneal trephine

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1089824A (en) * 1993-01-19 1994-07-27 中国人民解放军军事医学科学院放射医学研究所 Cornea cutter
US6371966B1 (en) * 1998-09-30 2002-04-16 Becton, Dickinson And Company Corneal incision device
RU2158571C1 (en) * 1999-12-27 2000-11-10 ГУ МНТК "Микрохирургия глаза" Device for marking-out of uncisions of eye cornea at phacoemulsification of cataract on eye with miotic pupil
US6840947B2 (en) * 2000-10-12 2005-01-11 Moria Sa Device for surgery of the cornea
WO2003026542A1 (en) * 2001-09-21 2003-04-03 Geuder Ag Eye surgical instrument
CN2579388Y (en) * 2002-12-03 2003-10-15 赵广华 Corneal epithelium valve forming device
US20070083087A1 (en) * 2005-10-12 2007-04-12 Sismed, Llc Fixator with membrane
JP2007130334A (en) * 2005-11-11 2007-05-31 Kenji Yoshida Constant depth cornea loop incision apparatus
US20070129741A1 (en) * 2005-12-07 2007-06-07 Weston Philip D Artificial anterior chamber for use in keratoplasty
US20070185509A1 (en) * 2006-02-02 2007-08-09 Nidek Co., Ltd. Corneal incision apparatus and blade case for storing blade unit to be mounted in the corneal incision apparatus
CN202821802U (en) * 2012-08-31 2013-03-27 北京大学第三医院 Corneal trephine

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107028700A (en) * 2017-04-05 2017-08-11 青岛大学附属医院 Corneal epithelial flap former and corneal epithelial flap forming method
CN108186194A (en) * 2018-01-03 2018-06-22 沈阳何氏眼科医院有限公司 Ophthalmologic operation ultrasound knife
CN108578061A (en) * 2018-07-10 2018-09-28 上海市同济医院 A kind of limbal stem cell transplantation device
CN108578061B (en) * 2018-07-10 2024-04-02 上海市同济医院 Limbal stem cell transplanting device
CN109106501A (en) * 2018-10-09 2019-01-01 北京航空航天大学 A kind of ophthalmologic operation ring cutting device with force sensing function
CN109106501B (en) * 2018-10-09 2020-10-27 北京航空航天大学 Ophthalmic surgery circular cutting device with force sensing function

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Application publication date: 20121226