CN102835566A - Chinese herbal medicine feed additive capable of improving immune and disease-resistant ability of livestock - Google Patents

Abstract

The invention relates to a Chinese herbal medicine feed additive capable of improving immune and disease-resistant ability of livestock. The Chinese herbal medicine feed additive is prepared according to the following steps of: mixing and smashing 35-45 parts of honeysuckle vine, 10-20 parts of liquorice residue, 10-20 parts of ginkgo leaf, 5-10 parts of astragalus root, 10-20 parts of hawthorn and 5-10 parts of wolfberry, and mixing with flour according to proportion part by weight of 1: (3-3.4). The Chinese herbal medicine feed additive has health-care effects of bacteria inhibition, virus resistance, growth promotion and the like, is wide in raw material source and low in production cost, is safe and non-toxic, has good palatability, and can be used for improving the meat quality of livestock.

Description

A kind of Chinese herbal feed additive that can increase the fowl poultry immune resistance against diseases

Technical field

The present invention relates to a kind of feed addictive, relate to a kind of Chinese herbal feed additive that can increase the fowl poultry immune resistance against diseases or rather.

Background technology

At present, increasing insider recognizes that conventional medicine feed addictives such as using antibiotic, somatropin, anticorrisive agent, anti-oxidant, disinfectant in the poultry and livestock feed is to the potential threat of human health.These traditional feed addictives have multiple harm: the one, in feed, add antibiotic for a long time; Can bring out high resistant microorganism crowd's in the fowl carcass generation; Because these microorganisms have the ability of antagonism antibiotic; In a single day thereby infect human body, patient is pasted medical help, thereby the mankind are caused great threat; The 2nd, add artificial synthetic somatropin in the feed, make the fowl dirty swine long unusual, product has lost original nutritive value and local flavor, and quality descends, and commodity value reduces; The 3rd, the synthetic chemicals of manual works such as antibiotic, somatotropin, anticorrisive agent, anti-oxidant, disinfectant often has toxic and side effect; Can cause distortion, the sudden change of normal tissue cell even cause canceration; Be detrimental to health; These chemical substances are through the enrichment of fowl poultry, under in the liver of fowl poultry and muscle, accumulating in large quantities, have more aggravated harmfulness; In addition, also possibly there is the not clear toxic and side effect of some other mechanism in these chemicalses, cause potential threat.Therefore, the numerous and confused proposal that proposes to ban use of antibiotic and short long hormone of some developed countries, and successively formulate the relevant law bill, make this proposal legalization.Development and use China Chinese herbal medicine resource, replacing conventional antibiotic, somatotropin and chemicals additive with Chinese herbal medicine is the most promising developing direction.Chinese herb feed additive utilizes pure medicinal plant root, stem, leaf and fruit to be raw material, has no side effect, no hazard residue in the fowl carcass, meets the developing direction of ecological food and pollution-free food, caters to the needs of domestic and international market.

Improve the existing many reports of immunity of body at home and abroad as feed addictive with Chinese herbal medicine.But because present research mostly lacks systematicness, with reference to the prescription that is used for human body therapy, do not use Chinese pharmacology, pharmacy, pharmacology principle to come to study targetedly livestock and poultry animal often, seldom consider the collaborative or antagonism between each composition yet.On March 29th, 2006; Chinese invention patent publication number CNl751587A discloses a kind of increase livestock and poultry resistance against diseases; Reduce the feed addictive of cholesterol blood fat; Be that the tuber of multiflower knotweed 20 gram, the red sage root 30 grams, cassia seed 30 grams, giant knotweed 28 grams, oriental wormwood 50 grams, hawthorn 40 grams, the root of kudzu vine 20 grams, dried orange peel 20 grams, folium isatidis 25 grams, ginkgo leaf 40 grams, root tuber of aromatic turmeric 30 grams, parasitic loranthus 50 grams, perilla leaf 27 grams, bluish dogbane 60 grams, pseudo-ginseng 40 grams, Asian puccoon 40 grams, the Radix Astragali 45 grams, honeysuckle 50 gram processing are concocted and pulverized, press 1.5%-2% and add hello livestock and poultry in the feed.This prescription uses Chinese medicine to reach 18 kinds; Wherein valuable medicinal consumptions such as the tuber of multiflower knotweed, the red sage root, pseudo-ginseng, parasitic loranthus are too high; Compatibility is science, action effect instability not, has so not only increased the cost while but also has limited the feed formula space, also can produce the palatability of feed sometimes and suppress.

The company at the applicant place be a family with rare traditional Chinese medicine honeysuckle plantation exploitation, raw material reclaim, produce, processing and to sell be the private scientific and technological enterprises of one.Company sets up large tracts of land honeysuckle production base, and production honeysuckle tribute tea, honeysuckle beverage need use a large amount of honeysuckles and licorice raw material, and producing the main discarded object that is produced is honeysuckle rattan and glycyrrhiza residue; The research that discarded object is utilized again is the direction that company makes great efforts to develop.

Summary of the invention

In order to overcome above defective; The technical problem that the present invention will solve is: propose a kind of Chinese herbal feed additive that can increase the fowl poultry immune resistance against diseases; Have medical care effects such as antibacterial, antiviral, growth promotion; Have low, the safety non-toxic of production cost, good palatability also can improve animal meat quality.

The technical scheme that the present invention adopted is: a kind of Chinese herbal feed additive that can increase the fowl poultry immune resistance against diseases, and it is by the following weight parts proportion raw material, through after mix pulverizing, again with flour by weight ratio 1: 3-3.4 is mixed with and forms:

Honeysuckle rattan 35-45 part, glycyrrhiza residue 10-20 part, ginkgo leaf 10-20 part, Radix Astragali 5-10 part, hawthorn 10-20 part, matrimony vine 5-10 part.

Honeysuckle rattan of the present invention is perennial half an evergreen winding woody climber of honeysuckle, reaches 9m.Stem hollow, multi-branched, sprout is close by pubescence and glandular hairs, and leaf is to life.Bright leaf and stem branch contain the Luteolin of multiple chromocor derivative, have lonicerin (lonicerin), loniceraflavone (loniceraflavone, 5,6,4 '-trihydroxyflavone), loganin (loganin) and tannin 8%.Nature and flavor are sweet, and are cold.Attach to the lung and stomach meridians.Have clearing heat and detoxicating, the dispelling wind vein relaxing.Above-mentioned Luteolin has multiple pharmacologically active, like anti-inflammatory, antiallergy, antitumor, antibiotic, antiviral etc., clinically is mainly used in cough-relieving, eliminates the phlegm, anti-inflammatory, treatment angiocardiopathy, treatment " amyotrophic lateral sclerosis ", SARS, hepatitis etc.The same usefulness of the honeysuckle rattan and the Radix Astragali, the ability strengthening vital QI to eliminate pathogenic factors, the holder poison is gone out, and makes in the purulence person to disappear, and the person promptly bursts to have become purulence.

Radix Glycyrrhizae slag system Radix Glycyrrhizae of the present invention is extracted the byproduct behind glycyrrhizic acid or the licorice root ointment, is rich in licoflavone content and antioxidation activity thing thereof, the Radix Glycyrrhizae dregs of a decoction be a kind of preciousness can utilize resource again.Liquorice flavonoids compound liquiritin, liquiritigenin and asparagus fern phthalein amine, sweet mellow wine have the restraint of tyrosinase activity, remove oxygen radical, have the effect of anti-inflammatory, antiallergic action, can also suppress capillary permeability.Be used for weakness of the spleen and the stomach, lassitude hypodynamia, severe palpilation, intermittent pulse.Report according to Japanese scholar TaKagi: flavones ingredient has the effect of anti-experiment peptic ulcer, antiinflammatory action.Can strengthen the antagonism of animal body HIV (HIV).

Ginkgo leaf of the present invention (Folium Ginkgo), Chinese different name: folium ginkgo bilobae, (English) GinkgoLeaf is the dried leaves of Ginkgoaceae plant Ginkgo biloba Ginkgo biloba L.Contain ginkgolide A, B, C class (Ginkgolides A, B, C), Kaempferol (Kacmpfero1), Quercetin (Quercetin), rutin (Rutin), gingko two yellow (Ginkgeting), flavonols (Flavono1) or the like.Property is put down, and it is sweet, bitter, puckery to distinguish the flavor of.The thoughts of returning home, lung channel.Have and astringe the lung, relieving asthma, promoting blood circulation and removing blood stasis, pain-relieving functions.Being used for the deficiency syndrome of the lung coughs and breathes heavily; The coronary disease pain, angina pectoris, high fat of blood.

Radix Astragali nature and flavor of the present invention: sweet, temperature.Gui Jing: lung channel, the spleen channel.Function: invigorating qi for strengthening superficies, inducing diuresis to reduce edema, pus draining and toxin expelling, expelling pus and promoting granulation.Can strengthen the phagocytic function of reticuloendothelial system, blood leukocytes and multinuclear leucocyte quantity are being shown to be increased, and macrophage phagocytic percentage and phagocytic index is being shown rise, and humoral immunity, cellular immunity are all had facilitation.The Radix Astragali can promote serum hemolysin to form, and improves plaque forming cells's haematolysis ability, the effect that the tangible carbon clearance effect of tool is heavy with increasing spleen.More than act under the normal physiological status and exist, obvious effect is arranged when immunologic hypofunction equally.The Radix Astragali not only has humidification to immunologic hypofunction, also has dual regulation.The active ingredient F3 of the Radix Astragali shows in vitro test has restitution completely to cancer patient's lymphocyte function; Demonstrate in the animal model test in vivo and can all reverse the immunosupress phenomenon that endoxan causes, the prompting astragalus root components possibly be a kind of BRM that gets a good chance of in immunization therapy.The activity of the NK (LAK) that the lymphokine that can also improve the Radix Astragali activates.

Hawthorn of the present invention contains chlorogenic acid (chlorogenic acid), caffeic acid, crataegolic acid (crataegolic acid), neat chrysanthemum tartaric acid, Quercetin, ursolic acid, oleanolic acid, hyperin (hyperin), epicatechin (epicatechin) etc.Since ancient times, just become the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting.Hawthorn contains materials such as carbohydrate, protein, fat, vitamin C, carrotene, starch, malic acid, citric acid, calcium and iron, has effects such as reducing blood lipid, blood pressure, cardiac stimulant and arrhythmia.Flavone compound Vitex negundo var cannabifolia in the hawthorn is plain, is the stronger medicine of a kind of antitumaous effect, and haw thorn extract all has certain inhibitory action to growth in the cancer cell body, propagation and infiltration metastasis.

(formal name used at school: Lycium chinense) contain fruit of Chinese wolfberry polysaccharide, it is sweet to distinguish the flavor of for matrimony vine of the present invention; Property is put down.Return Liver Channel; Kidney channel; Lung channel.The fruit of Chinese wolfberry has the blood sugar of reduction, lipotropy, and can antiatherosclerosis.Fruit of Chinese wolfberry polysaccharide can promote immunization.

Chinese herbal feed additive of the present invention contains materials such as several amino acids, vitamin, trace element; Through improving microbial environment in the enteron aisle, removing free radical; Improve the immunity of livestock and poultry body; Particularly the present invention adopts honeysuckle rattan and the same usefulness of the Radix Astragali, can decompose livestock and poultry vivotoxin deposition, strengthens body liver detoxification ability; Heavy metal ion such as adsorption removal lead, arsenic, cadmium are removed or are alleviated the negative effect (fluffy and disorderly like fur, the colour of skin is pale, poor growth etc.) of using the heavy metal ion that inorganic microelement causes because of feed in a large number; Absorption gets into the mycotoxin of enteron aisle, and the long-term use of the injury that the alleviation mycotoxin causes can be livestock and poultry and sets up long-acting nutritious immunologic mechanism, makes up firm disease protective barrier, improves the livestock and poultry resistance against diseases, impels livestock birds health growth (production).The present invention prevents the various diseases of livestock, has improved the survival rate of cub greatly, and it is more vivaciously strong to make into poultry; Its safety non-toxic, have no drug resistance, antibiotic-free is residual; Good palatability and because what take in is natural plant has improved meat to a great extent, is rich in the useful drug ingedient of pair health in the meat; Have more medication value than feed long poultry, domestic animal with normal diet, meat taste is delicious more.The present invention compared with prior art, its adopts company downstream is honeysuckle rattan and glycyrrhiza residue discarded object, raw materials enjoy stable sources, cheap, production technology is simple.

Specific embodiment

Embodiment 1: with honeysuckle rattan 40 grams, and glycyrrhiza residue 15 grams, ginkgo leaf 15 grams, the Radix Astragali 8 grams, hawthorn 15 grams, matrimony vine 7 grams.After mixing pulverizing, even with flour 300 gram mixed together again; Add in the feed by 1.5%, feed live pig and used 8-10 days, promptly visible live pig body temperature is normal, and ight soil is smooth, high resilience, and feed digestion is thoroughly.Feed intake increases more than 10%.Produced obvious fowl immune disease-resistance ability.

Embodiment 2: with honeysuckle rattan 42 grams, and glycyrrhiza residue 12 grams, ginkgo leaf 15 grams, the Radix Astragali 6 grams, hawthorn 20 grams, matrimony vine 5 grams.After mixing pulverizing, even with flour 300 gram mixed together again.Add in the feed by 1%, feed live pig and used 8-10 days, promptly visible live pig body temperature is normal, and ight soil is smooth, high resilience, and feed digestion is thoroughly.Feed intake increases more than 8%, has produced obvious fowl immune disease-resistance ability.

Embodiment 3: with honeysuckle rattan 40 grams, and glycyrrhiza residue 20 grams, ginkgo leaf 10 grams, the Radix Astragali 10 grams, hawthorn 10 grams, matrimony vine 10 grams.After mixing pulverizing, even with flour 300 gram mixed together again.Add in the feed by 2%, feed live pig and used 8-10 days, promptly visible live pig body temperature is normal, and ight soil is smooth, high resilience, and feed digestion is thoroughly.Feed intake increases more than 12%.Produced obvious fowl immune disease-resistance ability.

Embodiment 4: with honeysuckle rattan 45 grams, and glycyrrhiza residue 10 grams, ginkgo leaf 20 grams, the Radix Astragali 10 grams, hawthorn 10 grams, matrimony vine 5 grams.After mixing pulverizing, even with flour 340 gram mixed together again; Add in the feed by 1.0%, feed chicken and used 60 days, promptly visible chicken feather is smooth, and feed digestion thoroughly.The incidence of disease and case fatality rate are less than 5%.

Embodiment 5: with honeysuckle rattan 35 grams, and glycyrrhiza residue 20 grams, ginkgo leaf 10 grams, the Radix Astragali 5 grams, hawthorn 20 grams, matrimony vine 10 grams.After mixing pulverizing, even with flour 320 gram mixed together again.Add in the feed by 2%, feed ox and used 30 days, promptly visible buphthalmos is bright to have god, and ear is flexible, and feed intake increases more than 5%.

Embodiment 6: with honeysuckle rattan 38 grams, and glycyrrhiza residue 16 grams, ginkgo leaf 12 grams, the Radix Astragali 8 grams, hawthorn 18 grams, matrimony vine 8 grams.After mixing pulverizing, even with flour 330 gram mixed together again.Add in the feed by 1.5%, feed flock of sheep and used 20 days, promptly visible flock of sheep temperature is normal, and hair is smooth flexible, and feed digestion is thorough.Feed intake increases more than 5%.Produced obvious fowl immune disease-resistance ability.

Claims (1)

1. the Chinese herbal feed additive that can increase the fowl poultry immune resistance against diseases is characterized in that, it is by the following weight parts proportion raw material, and through after mix pulverizing, again with flour by weight ratio 1: 3-3.4 is mixed with and forms:

Honeysuckle rattan 35-45 part, glycyrrhiza residue 10-20 part, ginkgo leaf 10-20 part, Radix Astragali 5-10 part, hawthorn 10-20 part, matrimony vine 5-10 part.