CN102824196A - Reeling device of biological bolt and manufacturing method thereof - Google Patents

Reeling device of biological bolt and manufacturing method thereof Download PDF

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Publication number
CN102824196A
CN102824196A CN2012103344219A CN201210334421A CN102824196A CN 102824196 A CN102824196 A CN 102824196A CN 2012103344219 A CN2012103344219 A CN 2012103344219A CN 201210334421 A CN201210334421 A CN 201210334421A CN 102824196 A CN102824196 A CN 102824196A
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mobile platform
platform
mobile
biological
bolt
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CN102824196B (en
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闫晓荣
刘仰斗
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SHAANXI RUISHENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd
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SHAANXI RUISHENG BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd
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Abstract

The invention relates to a reeling device of a biological bolt for treating fistula and a manufacturing method thereof. The device is provided with a clamping rotary device, a pneumatic tension slide platform, a motor fixing block, a movable platform, a movable platform guiding device, a movable platform moving device, an equipment substrate and a control system, wherein the clamping rotary device is mounted on the equipment substrate through the pneumatic tension slide platform and the motor fixing block; the movable platform is fixedly arranged on the equipment substrate in a vertical direction through the movable platform guiding device and the clamping rotary device; and the movable platform moving device is arranged between the movable platform and the equipment substrate and can be used for driving the movable platform to move frontwards and backwards. According to the reeling device of the biological bolt for treating the fistula, the production efficiency is improved by 1/2-3/4; the uniform yield can be improved to more than 95%; the product yield is improved to more than 85%; and the biological bolt can be reeled by reeling cores with different lengths and softness degrees so that the requirements of different patients are met.

Description

A kind of rolling device of biological bolt and manufacture method
Technical field
The invention belongs to tissue engineering biomaterial for medical purpose technology, specifically a kind of treat biological bolt that fistula uses roll processing unit (plant) and preparation method thereof.
Background technology
Fistula is the pathologic pipeline of long-term disunion between hollow organ and hollow organ, hollow organ and skin or the mucosa, and the opening more than 2 is arranged usually.The conventional method of clinical treatment fistula is an operative treatment, and there is certain risk in operative treatment, and patient's postoperative rehabilitation phase misery is bigger.In recent years, along with the development of tissue engineering technique, bring into use the method for the method replacement operation of tissue engineering bracket material, can exempt treatment institute's risk of bringing and misery, its development and exploitation have become the focus of fistula treatment.
Biological bolt is a kind of tapered plug shape product, is to adopt tissue engineering bracket material to roll to form.Its Therapeutic Method is: after the debridement of fistula road, biological bolt is penetrated the fistula road through internal orifice, involve from collar extension, biological bolt is placed in the fistula road; Biological bolt bottom surface and fistula road junction are sewed up, sealing fistula road internal orifice; Cut fistula road collar extension excess stock, to the wound wrapping that carries out disinfection, collar extension more change dressings until healing.The pyramidal structure of biological bolt plays the occupy-place effect in fistula, transmitting tissue grows into, thereby realizes tissue reconstruction; The internal orifice closure is easier to healing, and collar extension does not seal the effect that key can play drain again, prevents false healing.
Because tissue engineering technique also is in the starting stage, the processing and fabricating of biological bolt does not still have sophisticated special equipment and produces utensil, is mostly to adopt the artificial method that rolls at present: be tiled in the membranous tissue engineering material on the material flat board, and cut into suitable shape.The volume core is placed on one side of material, and on the volume core, hand-turned volume core is directly put into corresponding mould, lyophilizing after material twists on the core fully and forms the taper outward appearance, be rolled with the material twisting cohesion.There is following shortcoming in the method that this craft rolls: 1. production leans on operator's experience to carry out, and production efficiency is low, and cost is high; 2. different because of operator, the biological bolt thickness, the degree of tightness that very easily occur rolling are different, and product quality and specification are difficult to control, are difficult to the realization standardized production; 3. in operation process, rolling by hand increases pollution risk more easily, causes product endotoxin, cytotoxicity etc. to exceed standard.
Summary of the invention
Produce the shortcoming that biological bolt exists to present manual work, the object of the present invention is to provide a kind of semi-automatic rolling device and manufacture method of making biological bolt.
The present invention mainly contains and clamps rotary apparatus, pneumatic tensioning slide unit, motor fixed block, mobile platform, mobile platform mobile device, mobile platform guider, equipment substrate in order to produce the device of biological bolt, and control system is formed.Clamping rotary apparatus is installed on the equipment substrate through pneumatic tensioning slide unit and motor fixed block respectively; Mobile platform is fixed on the equipment substrate through mobile platform guider and clamping rotary apparatus in vertical direction; The mobile platform mobile device is installed between mobile platform and the equipment substrate, can drive mobile platform and move forward and backward.
Said clamping rotary apparatus is two covers, and each is made up of shaft coupling, air spider and electric rotating machine.Two covers clamp between the rotary apparatus coaxial relative; Horizontal interval 15-30cm; Be installed in respectively on it corresponding pneumatic tensioning slide unit and the motor fixed block: the one group of clamping rotary apparatus that is connected with pneumatic tensioning slide unit can move horizontally, and the one group of clamping rotary apparatus that is connected with the motor fixed block is not removable.In the middle of air spider was positioned at, electric rotating machine was in the outside, and shaft coupling one side is connected with spin motor shaft, and opposite side and air spider are fixed, as the transmission connection of turning moment.The air spider front end has 3-6 to prop up the claw that can inwardly clamp of rounded array; The air spider interposition is equipped with two compressed air inlet ports; Respectively two air inlets being fed compressed air---gathering and release of may command claw, the claw grasp is by the decision of compressed-air actuated air pressure size.Claw is made by the steel alloy material, can fastening diameter 0.7-50mm column.
Said pneumatic tensioning slide unit, it is fixedly connected with electric rotating machine; Pneumatic slide unit bottom surface is fixedly connected with the equipment substrate.Pneumatic tensioning slide unit is by compressed air-driven, and the air pressure size that tensile force is supplied with by pneumatic tensioning slide unit determines.Through moving of pneumatic tensioning platform, connected clamping rotary apparatus is moved in horizontal direction, to reach the purpose of stretching volume core.
Said mobile platform is processed into by stainless steel.The slide block that mobile platform is connected with its bottom surface is nested in two covers and clamps in the middle of the rotary apparatuss through being fixed on slide rail on the equipment substrate, and clamps rotary apparatus in vertical direction, and can move forward and backward along the slide rail direction.Mobile platform can be placed the tissue engineering material to be used of any specification, and rolls work at its surface biological bolt of completion.
Said mobile platform mobile device is made up of with nut platform mobile motor, lead screw, the solid mounting assembly of leading screw and leading screw.The platform mobile motor is fixed on the equipment substrate in the middle of two slide rails near clamping rotary apparatus one side, and platform mobile motor axle and slide rail are parallel direction.Lead screw one end is connected with platform mobile motor axle, and the other end is connected with the solid mounting assembly of leading screw.Through the nested interlock with leading screw of screw thread, fix by its stationary plane and mobile platform underrun screw with nut for leading screw.Through the rotation of lead screw, leading screw is transformed into the moment with the slide rail parallel direction with nut with the turning moment of platform mobile motor, and moves forward and backward through motor positive and inverse control mobile platform, and translational speed is determined by platform mobile motor rotary speed.
Said mobile platform guiding mechanism is made up of slide rail and slide block.Two one slide rails are fixed on the equipment substrate, and are parallel with leading screw in the mobile platform mobile device and be positioned at its lateral symmetry and install, and mobile platform bottom surface and slide block are fixed.Slide block is nested on the slide rail, and can move forward and backward along the slide rail direction.
Said equipment substrate is processed into by stainless steel, and feet is installed, and is convenient to putting leveling and moving of this device.
Said control system comprises touch screen, Programmable Logic Controller, motor driver and electromagnetic valve; Touch screen is used for showing and parameters being set, comprises rotating speed, the air spider of platform mobile motor and two electric rotating machines, the pressure of pneumatic tensioning slide unit, mobile platform displacement; And the gathering and discharge of control air spider.Programmable Logic Controller is used for the procedure stores operation and issues operating instruction, and its expansion input is connected with touch screen, and signal output part is connected with motor driver, electromagnetic valve.The signal input part of motor driver is connected with Programmable Logic Controller, and signal output part is connected with electric rotating machine, platform mobile motor respectively---may command motor speed, direction.The signal input part of electromagnetic valve is connected with Programmable Logic Controller, realize gathering, discharging of claw through opening or closing compressed-air actuated path, and whether may command tensioning pneumatic slide platform moves.
The method for coiling of the present invention's biological bolt and step are described below:
1. open device power supply (DPS), set electric rotating machine rotating speed, mobile platform translational speed and displacement, compressed air pressure be provided by air compressor through the touch screen of control section.
2. will cut into the moistening tissue engineering bracket material of suitable shape and size, and be placed on the mobile platform, the metal handle that will roll up the core two ends then is positioned over respectively in the expansion chuck claw.Start the clamping button, claw will be rolled up core and be fixedly clamped.
3. press touch screen operation button, the operation of stretching rotary apparatus, the clamping rotary apparatus that is connected with pneumatic slide unit moves, and the volume core is straightened, and beginning rotation under rotary apparatus drives.
Mobile platform with setting speed to the volume core near, tissue engineering bracket material with after the volume core contact, under the liquid tension effect, material is attached to beginning rotation on the volume core and with rolling up core.
5. when material was coated on the volume core fully, mobile platform halted after arriving and setting displacement, and after rotary apparatus stopped the rotation, the air spider claw discharged automatically, and mobile platform and biological bolt return initial position together, and the process that rolls finishes.
Reappose new tissue engineering material, and the volume core is installed, can begin second and take turns and roll.
The making of the present invention's biological bolt; Also can adopt semi-automatic method for preparing: drive the rotation of volume core through dynamic Control; Surface tension of liquid effect by tissue engineering material; It is attached on the volume core naturally, and the volume core continues rotation, and tissue engineering material is twisted in fully obtains biological bolt on the core.
Biological bolt rolling device of the present invention and method for using roll with present manual work and to compare, and have the following advantages:
(1) according to experiment statistics, use this device to roll biological bolt, the needed time has only manual 1/2 to 3/4 of the biological bolt of fistula that rolls, and has improved production efficiency.
(2) use this device to roll biological bolt, roll respectively to move in the process and all can set relevant parameter according to actual needs, roll biological bolt stress equalization in the process, big or small length is unified.Manual work at present rolls biological bolt homogeneity and receives many-sided influence such as operator's individuality, experience, maneuver, and the homogeneity qualification rate is about 80%, and this device homogeneity qualification rate can be promoted to more than 95%.
(3) adopt this device to roll the biological bolt of fistula; Through control volume core rotary speed and mobile platform feed speed; The biological bolt that can prepare the different soft and hard degree; Therefore rolling biological bolt density and soft or hard degree can strict control, thereby guarantees with the manufacturing quality that reaches product between the different batches product between the batch products.
(4) adopt this device to roll the biological bolt of fistula, reduced artificial participation process, reduce manual pollution risk of bringing into; Improve product percent of pass; According to experiment statistics, it is about 70% that manual work rolls qualification rate, adopts the inventive method to roll product percent of pass and is increased to more than 85%.
(5) adopt this device to roll the biological bolt of fistula,, can adjust automatically and make volume core level stretching,, satisfy different patients' needs so this device can use the volume core of different length and soft or hard degree to roll biological bolt because be designed with pneumatic tensioning slide unit.
Below in conjunction with accompanying drawing and embodiment the present invention is explained further details.
Description of drawings
Fig. 1 is that the master that the biological bolt rolling device integral body by the embodiment of the invention constitutes looks sketch map:
Fig. 2 is the schematic top plan view that the biological bolt rolling device integral body by the embodiment of the invention constitutes;
Fig. 3 is the clamping device sketch map of the biological bolt rolling device of present embodiment;
Fig. 4 is the rolling device mobile platform sketch map of present embodiment;
Fig. 5 is the flexibility volume core sketch map of present embodiment.
Among the figure: 1, feet, 2, the equipment substrate, 3, pneumatic tensioning slide unit, 4, electric rotating machine, 5, shaft coupling; 6, air spider, 7, slide rail, 8, slide block, 9, lead screw, 10, leading screw uses nut; 11, platform mobile motor, 12, the volume core, 13, mobile platform, 14, the motor fixed block, 15, claw; 16, claw clamps and to be discharged into QI KOU, and 17, tissue engineering material, 18, metal handle, 19, the line body.
The specific embodiment
Embodiment 1
The main accessory model that present embodiment adopts is following: electric rotating machine and necessary electromotor driver: servo A4 series MHMD022P1U motor of Panasonic and supporting MADDT1207003 driver; Platform mobile motor and necessary electromotor driver: servo A4 series MHMD022P1U motor of Panasonic and supporting MADDT1207003 driver; Touch screen: the GT1155-QSBD-C of SANLING; Programmable Logic Controller: the FX1N-24MR-001 of SANLING; The VF3530-4G-02 of electromagnetic valve: SMC; Air spider: JAP100 precise pneumatic chuck of diaphragm; Lead screw and supporting leading screw are used nut: the MTATR-10-50 of MISUMI and supporting nut support; The SE2BSZ-10-70 of slide rail and slide block: MISUMI; Pneumatic tensioning slide unit: the MXPJ6 of SMC; Flexible volume core: diameter is the 15cm operation suture thread for 0.5mm length, and two ends are equipped with long 1.5cm diameter 1mm cylindrical metal handle.
Fig. 1, Fig. 2 are from the main structure that has shown present embodiment with depression angle of looking
The biological bolt rolling device of present embodiment, by clamping rotary apparatus, pneumatic tensioning slide unit 3, motor fixed block 14, mobile platform 13, mobile platform mobile device, mobile platform guider, equipment substrate 2, control system is formed.Clamping rotary apparatus is installed on the equipment substrate 2 with motor fixed block 14 through pneumatic tensioning platform 3 respectively; Mobile platform 13 is fixed on the equipment substrate 2 through mobile platform guider and clamping rotary apparatus in vertical direction; The mobile platform mobile device is installed between mobile platform 13 and the equipment substrate 2, can drive mobile platform 13 and move forward and backward.
Fig. 3 has shown that present embodiment clamps the structure of rotary apparatus: clamping rotary apparatus is two covers, and each is made up of shaft coupling 5, air spider 6 and electric rotating machine 4.Two covers clamp between the rotary apparatus coaxial relative; Horizontal interval 20cm; Be installed in respectively on corresponding with it pneumatic tensioning slide unit 3 and the motor fixed block 14; The one group of clamping rotary apparatus that is connected with pneumatic tensioning slide unit 3 can move horizontally, and the one group of clamping rotary apparatus that is connected with motor fixed block 14 is not removable.Air spider 6 is in the centre, and electric rotating machine 4 is in the outside, and shaft coupling 5 one sides are connected with spin motor shaft, and opposite side and air spider 6 are fastening through screw.Air spider 6 front ends have the claw that can inwardly clamp 15 of 4 rounded arrays; Air spider 6 interpositions are equipped with the claw clamping and are discharged into QI KOU 16; Compressed air inlet port feeds compressed air to two air inlets respectively---and gathering and release of control claw 15, the grasp of claw 15 is by the decision of compressed-air actuated air pressure size.Claw 15 is made by the steel alloy material, can fastening diameter 0.7-50mm column;
Between said pneumatic tensioning slide unit 3 and the motor fixed block 14, fix through screw; Pneumatic tensioning slide unit 3 bottom surfaces and equipment substrate 2 are fixed through screw.Pneumatic tensioning slide unit 3 is by compressed air-driven, and tensile force is supplied with the air pressure decision by pneumatic tensioning slide unit 3, drives moving of pneumatic tensioning platform 3.
Fig. 4 shows the structure of mobile platform: mobile platform 13 is nested in two covers and clamps in the middle of the rotary apparatuss through being fixed on slide rail 7 on the equipment substrate through the slide block 8 that is connected with its bottom surface; With clamp rotary apparatus in vertical direction, and can move forward and backward along slide rail 7 directions.Mobile platform 13 is in order to placing any specification tissue engineering material 17 to be used, and accomplishes biological bolt on its surface and roll work.Be processed into by stainless steel.
Said mobile platform mobile device is made up of with nut platform mobile motor 11, lead screw 9, the solid mounting assembly of leading screw and leading screw.Platform mobile motor 11 be fixed on two slide rail 7 centres on the equipment substrate near clamping rotary apparatus one side, 11 of platform mobile motors are parallel direction with slide rail 7.Leading screw 9 one ends are connected with platform mobile motor axle, and the other end is connected with the solid mounting assembly of leading screw.Through screw thread and lead screw 9 nested interlocks, fix by its stationary plane and mobile platform 13 underrun screws with nut 10 for leading screw.Rotation through lead screw 9; Leading screw is transformed into the moment with slide rail 7 parallel directions with nut 10 with the turning moment of motor; And move forward and backward through platform mobile motor 11 rotatings control mobile platform 13, translational speed is determined by platform mobile motor 11 rotary speeies.
Said mobile platform guiding mechanism is made up of slide rail 7 and slide block 8.Two one slide rails 8 are fixed on the equipment substrate 2, and are parallel with leading screw in the mobile platform mobile device 9 and be positioned at its lateral symmetry and install, and mobile platform 13 underrun screws and slide block 8 are fixed in the relevant position.Slide block 8 is nested on the slide rail 7, and can move forward and backward along slide rail 7 directions;
Said equipment substrate 2 is processed into by stainless steel, and feet 1 is installed, and is convenient to putting leveling and moving of this device;
Said control system comprises touch screen, Programmable Logic Controller, motor driver and electromagnetic valve; Touch screen is used for showing and parameters being set, and comprises rotating speed, air spider 6, the pressure of pneumatic tensioning slide unit 3, mobile platform 13 displacements of platform mobile motor 11, two electric rotating machines 4, and may command air spider 6 is gathered and discharged.Programmable Logic Controller is used for the procedure stores operation and issues operating instruction, and its expansion input is connected with touch screen, and signal output part is connected with motor driver, electromagnetic valve.The signal input part of motor driver is connected with Programmable Logic Controller, and signal output part is connected with electric rotating machine 4, platform mobile motor 11 respectively---may command motor speed, direction.The signal input part of electromagnetic valve is connected with Programmable Logic Controller, realizes gathering, discharging of claw 15 through opening or closing compressed-air actuated path, and the action of the pneumatic tensioning sliding platform 3 of may command.
Fig. 5 shows the structure of the flexible volume of present embodiment core: mid portion is the thread line body 19 of operation stitching, diameter 0.5mm length 15cm, and there is metal handle 18 at two ends, and the cylindrical 316L stainless steel material of length 1.5cm diameter 1mm is processed.
Said rolling with volume core 12 can be divided into flexible volume core and rigid volume core.Flexible volume core mid portion is that operation suture thread etc. is processed the line body, diameter 0.3-1.5mm, and length 10-25cm, there is metal handle 18 at two ends.The cylindrical 316L stainless steel material of length 1-4cm diameter 1-3mm is processed; Rigid volume core can use diameter to constitute as materials such as 0.3-1.5mm rustless steel or polyethylene.
Present embodiment adopts flexible volume core, and its rolling technology is following:
This device is placed in the superclean bench, opens stand-by power source.On touch screen, selecting volume core classification is wire member roll core 12, and setting volume core rotary speed is 60rpm, and setting the mobile platform pace is 11.5cm/min, and it is 27cm that platform displacement is set, and the adjustment admission pressure is 0.3MP.With submucous layer of small intestine according on the mobile platform 13 that is positioned over equipment shown in Figure 4.The private volume core of taking places fixation side rotating clamp air spider claw center with an end metal handle 18, presses corresponding claw close push button, and metal handle 18 is fixedly clamped by air spider claw 15.Fixing operation stitching thread other end metal handle is in opposite side rotating clamp air spider claw center.Press the operation of touch screen starting drive, pneumatic tensioning slide unit and connected rotary apparatus move and tension volume core to the left, and the volume core begins to rotate behind the 2s; Mobile platform moves forward; After submucous layer of small intestine touched the volume core, the material edge was rolled with the volume core under the tension force effect, rolled up core continuation rotation along with mobile platform 13 moves forward; Submucous layer of small intestine finally twists in fully and forms the biological bolt of taper on the core; Mobile platform 13 stops after continuing to move forward to setpoint distance, and rotating clamp stops, and discharges claw 15.Metal handle 18 drops out from claw 15 under the self gravitation effect, and biological bolt is placed on the mobile platform 13.Pneumatic tensioning slide unit stops, and the left side spin rotary device returns initial position, and mobile platform resets fast after 3 seconds.The process that rolls finishes.
Reappose submucous layer of small intestine, and installation volume core 12 can begin to roll work next time.Operator put into the lyophilizing mould with rolled a collection of biological bolt and carry out lyophilizing, promptly accomplish the whole machining process program.
The method for preparing of the semi-automation of embodiment 2. biological bolts: drive the rotation of volume core through dynamic Control; Surface tension of liquid effect by tissue engineering material; It is attached on the volume core naturally, and the volume core continues rotation, and tissue engineering material is twisted in fully obtains biological bolt on the core.

Claims (5)

1. the rolling device of a biological bolt; It is characterized in that having: clamp rotary apparatus, pneumatic tensioning slide unit (3), motor fixed block (14), mobile platform (13), mobile platform mobile device, mobile platform guider, equipment substrate (2) and control system; Clamping rotary apparatus is installed on the equipment substrate (2) through pneumatic tensioning slide unit (3) and motor fixed block (14) respectively; Mobile platform (13) is fixed on the equipment substrate (2) through mobile platform guider and clamping rotary apparatus in vertical direction; The mobile platform mobile device is installed between mobile platform (13) and the equipment substrate (2), can drive mobile platform (13) and move forward and backward;
Said clamping rotary apparatus has two covers, and each is made up of shaft coupling (5), air spider (6) and electric rotating machine (4); Two covers clamp between the rotary apparatus coaxial relative; Horizontal interval 15-30cm; Be installed in respectively on it corresponding pneumatic tensioning slide unit (3) and the motor fixed block (14): the one group of clamping rotary apparatus that is connected with pneumatic tensioning slide unit (3) can move horizontally, and the one group of clamping rotary apparatus that is connected with motor fixed block (14) is not removable; Air spider (6) is in the centre, and electric rotating machine (4) is in the outside; Shaft coupling (5) one sides are connected with spin motor shaft, and opposite side is fixedly connected with air spider (6); Air spider (6) front end has 3-6 to prop up the claw that can inwardly clamp (15) of rounded array; Air spider (6) interposition is equipped with two compressed air inlet ports (16), respectively two air inlets is fed compressed air---gathering and release of control claw (15);
Be fixedly connected between said pneumatic tensioning slide unit (3) and the electric rotating machine; Pneumatic tensioning slide unit (3) bottom surface is fixedly connected with equipment substrate (2); Pneumatic tensioning slide unit (3) moves connected clamping rotary apparatus horizontal direction by compressed air-driven;
Said mobile platform (13), the slide block (8) that its bottom surface connects is nested in two covers and clamps in the middle of the rotary apparatuss through being fixed on slide rail (7) on the equipment substrate, and clamps rotary apparatus in vertical direction, and moves forward and backward along slide rail (7) direction;
Said mobile platform mobile device; Form with nut (10) by platform mobile motor (11), lead screw (9), the solid mounting assembly of leading screw and leading screw; Platform mobile motor (11) be fixed on be positioned on the equipment substrate two slide rails (7) centre near clamping rotary apparatus one side, platform mobile motor axle and slide rail (7) are parallel direction; Lead screw (9) one ends are connected with platform mobile motor axle, and the other end is fixedly connected with the lead screw mounting assembly; Through the nested interlock with leading screw of screw thread, fix by its stationary plane and mobile platform underrun screw with nut (10) for leading screw;
Said mobile platform guiding mechanism is made up of slide rail (7) and slide block (8); Two one slide rails 7 are fixed on the equipment substrate (2), and are parallel with lead screw (9) in the mobile platform mobile device, and are positioned at its lateral symmetry installation, and mobile platform underrun screw and slide block (8) are fixing; Slide block (8) is nested on the slide rail (7), and can move forward and backward along slide rail (7) direction;
Said control system comprises touch screen, Programmable Logic Controller, motor driver and electromagnetic valve;
Touch screen and platform mobile motor (11) and two electric rotating machines (4), air spider (6), pneumatic tensioning slide unit (3), mobile platform (13) is electrically connected;
Programmable Logic Controller, its expansion input is connected with touch screen, and signal output part is electrically connected with motor driver, electromagnetic valve;
The signal input part of motor driver is connected with Programmable Logic Controller, and signal output part is electrically connected with electric rotating machine (4), platform mobile motor (11) respectively.
2. the manufacture method of biological bolt; It is characterized in that; One of method step is semi-automatic method for preparing: drive the rotation of volume core through dynamic Control, by the surface tension of liquid effect of tissue engineering material, it is attached on the volume core naturally; The volume core continues rotation, and tissue engineering material is twisted in fully obtains biological bolt on the core.
3. the manufacture method of biological bolt is characterized in that, two of method step is:
1) opens device power supply (DPS), set electric rotating machine (4) rotating speed, mobile platform (13) translational speed and displacement through the touch screen of control section;
2) will cut into the moistening organizational project biologic bracket material of suitable shape and size; Be placed on the mobile platform (13); To roll up core (12) two ends metal handle (18) then is positioned over respectively in the expansion chuck claw (15); Start the clamping button, claw (15) will be rolled up core (12) and be fixedly clamped;
3) press touch screen operation button, the operation of stretching rotary apparatus, the clamping rotary apparatus that is connected with pneumatic tensioning slide unit (3) moves, and volume core (12) is straightened, and rotation under rotary apparatus drives;
4) mobile platform (13) with setting speed to volume core (12) near, organizational project biologic bracket material with after volume core (12) contact, under the liquid tension effect, material is gone up attached to volume core (12) and is begun rotation with rolling up core;
5) be coated on volume core (12) last time fully when material; Mobile platform (13) halts after arriving and setting displacement, and after rotary apparatus stopped the rotation, air spider claw (15) discharged automatically; Mobile platform (13) and biological bolt return initial position together, and the process that rolls finishes.
4. according to the rolling device of the said biological bolt of claim 1, it is characterized in that, said equipment substrate (2), the below is provided with is convenient to put leveling and the feet (1) that moves.
5. according to the rolling device of the said biological bolt of claim 1, it is characterized in that: equipment substrate (2), process by stainless steel.
CN201210334421.9A 2012-09-11 2012-09-11 Reeling device of biological bolt and manufacturing method thereof Active CN102824196B (en)

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CN106419988A (en) * 2015-08-11 2017-02-22 陕西瑞盛生物科技有限公司 Fistula bolt rolling device preventing rolling adhesion and rolling method
CN106419989A (en) * 2015-08-11 2017-02-22 陕西瑞盛生物科技有限公司 Biomaterial rolling device and rolling method

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