The Chinese medicine decoction of Cure for insomnia
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction of Cure for insomnia.
Background technology
As everyone knows, insomnia all can take place throughout the year, is maximum with the spring.This is because of the climate variability in spring, usually makes normal person's anxious state of mind very fast, disturbs the inherent physiological function of people easily; Air pressure is low in addition, causes the excretory hormone disturbance of human brain easily.Poor like self adaptive capacity, cause the inside and outside disequilibrium, just bring out insomnia easily.The traditional Chinese medical science is thought, the liver belonging to wood, and the happiness bar reaches, and is corresponding with the yang-energy that spring rise to be sent out.Do not take good care of oneself if do not note feelings will, feelings will is unsuccessful, and irritability is depressed, and liver is lost bar and reaches, and being insomnia then appears in stagnated QI transforming into fire, disturbing the mind upwards.Show as difficulty falling asleep, discontinuous intermittently, and wake up prematurely, can not continue again to sleep after waking up; Do not have enough sleep, malaise, asthenia sensation, how not good because of health condition; Pain perception is uncomfortable, and circadian rhythm is upset, and sleep environment influence etc. also have and are afraid of sleep and insomnia.Insomnia is called " unable to close the eyes ", " insomnia ", " must not crouch " in " interior warp ", and thinks that the insomnia reason mainly contains two kinds, and the one, the influence of other diseases like cough, vomiting, abdominal distention etc., makes the people must not peacefully sleeping; The 2nd, negative and positive of qi and blood is become estranged, make the people not the able person sleep.Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study and health, and can increase the weight of or bring out diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy.Obstinate insomnia brings secular misery to patient, even forms the dependence to the medicine of sleeping peacefully, and can cause iatrogenic disease and take the medicine of sleeping peacefully for a long time.
Summary of the invention
The object of the invention is exactly in order to overcome above-mentioned existing technical deficiency a kind of Chinese medicine decoction of Cure for insomnia to be provided, and cost is low, do not have obvious toxic-side effects, and the treatment effective percentage is higher.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction of Cure for insomnia is characterized in that crude drug is formed to count with weight portion: Radix Codonopsis 13~18, Rhizoma Atractylodis Macrocephalae (parched) 13~18, Rhizoma Atractylodis (parched) 17~23, Poria 17~23; Herba Eupatorii 12~16, Fructus Piperis Longi 3~7, Semen Ginkgo core 3~7, jujube nucleus 18~25, Semen Platycladi 13~17; Caulis Polygoni Multiflori 28~34, Flos Albiziae 10~14, Radix Curcumae 14~16, Rhizoma Polygoni Cuspidati 14~16, Semen Armeniacae Amarum 8~11; Fructus Amomi Rotundus 10~13, Semen Coicis 28~34, Rhizoma Pinelliae Preparatum 8~12, Cortex Magnoliae Officinalis 8~12, Semen Nelumbinis 13~17; Radix Polygalae 16~20 is soaked in water above-mentioned 21 flavor crude drug after mixed Radix Ophiopogonis 7~10, remove slag after decocting filtrating.
Radix Codonopsis has invigorating the spleen and replenishing QI in the prescription of the present invention, and the effect of spleen invigorating lung benefiting is used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, and anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc., " Bencao Congxin " record: " invigorating the spleen and replenishing QI and taste, relieving thirst and restlessness.A little less than the middle feeble QI, mend in order to transfer, very smooth and proper."; The Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive, be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; The Rhizoma Atractylodis (parched) nature and flavor are hot, bitter, and temperature is returned spleen, stomach, Liver Channel, and is drying damp and strengthening spleen, and expelling wind and cold makes eye bright, and is used for distension and fullness in the abdomen, has loose bowels edema, rheumatic arthralgia, anemofrigid cold, nyctalopia; Poria property slightly sweet flavor is flat, goes into the heart, lung, spleen channel, has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, and the effect of mind tranquilizing and the heart calming can be controlled dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, malignant histocytosis is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade; The Herba Eupatorii nature and flavor are hot, and are flat, return spleen, stomach, lung meridian, expelling summer-heat and damp, ward off dirty with in, cure mainly experience heat-damp in summer, cold and heat headache, accumulate in moistening, the gastral cavity painful abdominal mass is not hungry, nausea and vomiting, mouthful in sweetly be bored with, disappear truly; The Fructus Piperis Longi warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving is used for coldness and pain in the epigastrium, vomits, has loose bowels, migraine, nasal sinusitis, external treatment toothache, coronary heart disease, angina pectoris, controls trusted subordinate's cold type of pain, vomiting acid regurgitation, increased borborygmus and diarrhea, cold-dysentery, scrotal hernia, headache, nasal sinusitis, toothache; Semen Ginkgo core is sweet, bitter, puckery, and is flat, poisonous, returns lung meridian, cures mainly astringing lung QI for relieving asthma, and leukorrhagia stopping is turbid, and urine reducing is used for abundant expectoration and breathes with cough, leukorrhagia nebulousurine, enuresis frequent micturition; The jujube nucleus nourishing the liver, mind calming is calmed the nerves, and arresting sweating is controlled restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility; The Semen Platycladi nature and flavor are sweet, and are flat, GUIXIN, kidney, large intestine channel, and tranquilizing by nourishing the heart, loosening bowel to relieve constipation is used for restlessness of asrhenia type and insomnia, severe palpitation, diseases such as dryness of the intestine constipation; Caulis Polygoni Multiflori nourishes heart, and calms the nerves, and collateral dredging dispels the wind, and cures mainly the insomnia, impairment caused by overstrain, and hyperhidrosis, the blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies, sweet little hardship, flat; The Flos Albiziae nature and flavor are sweet, and are flat, Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, the YIN nourishing kidney, clearing away heart-fire makes eye bright; The Radix Curcumae nature and flavor are hot, bitter, and are cold, return liver, the heart, lung meridian, regulating qi to disperse stagnation, and heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice is used for amenorrhea dysmenorrhea chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine; The little hardship of Rhizoma Polygoni Cuspidati is slightly cold, and returns liver, gallbladder, lung meridian, heat-clearing and toxic substances removing, and promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, the dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm is used for arthralgia, jaundice due to damp-heat, amenorrhea , WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus; Contain amygdaloside in the Semen Armeniacae Amarum, amygdaloside can be produced the hydrocyanic acid and the benzaldehyde of trace by enteric microorganism enzyme or the contained emulsin hydrolysis of Semen Armeniacae Amarum itself in vivo, and respiratory center is had inhibitory action, reaches antitussive, antiasthmatic effect; Fructus Amomi Rotundus has that good fragrance is good for the stomach, wind dispelling effect effect, can promote gastric secretion, and excited intestinal tube wriggling is driven away the enteral pneumatosis, and suppresses enteral abnormal fermentation; Semen Coicis is cool in nature, sweet in the mouth, light, and the spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, Semen Coicis can be used for treating edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen; Rhizoma Pinelliae Preparatum is hot, warm, returns spleen, stomach, lung meridian, and drying dampness to eliminate phlegm is used for the abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache; The Cortex Magnoliae Officinalis nature and flavor are bitter, suffering is warm in nature, return through spleen channel, and the stomach warp, large intestine channel, the circulation of qi promoting removing food stagnancy, dampness is removed full, and lowering the adverse QI to relieve asthma cures mainly: stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up the QI rising in reverse order, and fullness in the chest is breathed with cough; Semen Nelumbinis sweet in the mouth, puckery, property is flat, returns spleen, kidney, heart channel, has the function of supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, tranquilizing by nourishing the heart; Radix Polygalae is bitter, hot, tepor, and GUIXIN, kidney, lung meridian, the Fructus Alpiniae Oxyphyllae of calming the nerves is eliminated the phlegm, and detumescence is used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and is used for dryness of the lung dry cough, chronic consumptive disease cough; Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst; The dryness of the intestine constipation, pharyngeal diphtheria, YIN nourishing and the production of body fluid promoting; Nourishing the lung to arrest cough, thirsty, dry cough spitting of blood, cards such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat are lacked in the Tianjin that is used for lung-stomach yin deficiency.
The present invention is used for Cure for insomnia, and cost is low, do not have obvious toxic-side effects, and the treatment effective percentage is higher.
The specific embodiment
Below in conjunction with embodiment the present invention is done further description:
Embodiment 1:
Adopt Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Rhizoma Atractylodis (parched), Poria, Herba Eupatorii, Fructus Piperis Longi, Semen Ginkgo core, jujube nucleus, Semen Platycladi, Caulis Polygoni Multiflori, Flos Albiziae, Radix Curcumae, Rhizoma Polygoni Cuspidati, Semen Armeniacae Amarum, Fructus Amomi Rotundus, Semen Coicis, Rhizoma Pinelliae Preparatum, Cortex Magnoliae Officinalis, Semen Nelumbinis, Radix Polygalae, Radix Ophiopogonis; For crude drug is prepared from, its component (in weight portion) is: Radix Codonopsis 15, Rhizoma Atractylodis Macrocephalae (parched) 15, Rhizoma Atractylodis (parched) 20, Poria 18, Herba Eupatorii 14, Fructus Piperis Longi 5, Semen Ginkgo core 6, jujube nucleus 22, Semen Platycladi 15, Caulis Polygoni Multiflori 31, Flos Albiziae 13, Radix Curcumae 15, Rhizoma Polygoni Cuspidati 15, Semen Armeniacae Amarum 10, Fructus Amomi Rotundus 12, Semen Coicis 30, Rhizoma Pinelliae Preparatum 11, Cortex Magnoliae Officinalis 10, Semen Nelumbinis 15, Radix Polygalae 17, Radix Ophiopogonis 9, get 2.52 kilograms of above-mentioned 21 kinds of crude drug gross weights; After selected the cleaning; With 15000ml water logging bubble 3-4 hour, decoct 60 minutes then at ambient temperature, through the routine filtration of removing slag; High pressure; Behind the sterilization process, gained filtrating 4800ml, sterile bag packing; Sealing, every bag of 100ml.Early, late twice (medicine) being taken before meal, each oral one bag, 8 days is a course of treatment, each course of treatment is at a distance from three days, takes three courses of treatment of decoction of the present invention continuously.
But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (weight portion) is realized.Its processing technique is identical with embodiment 1.
Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Weihai City, Shandong Province women and children hospital is done further, is described in detail the present invention:
1, case is selected: this organizes 60 examples, male 21 examples, women 39 examples, age 15-53 year, 29 years old mean age, course of disease 2-7, average 4.6 years.
2, Therapeutic Method: early, late twice (medicine) being taken before meal, each oral one bag, 10 days is a course of treatment, and continuously took the present invention three courses of treatment at a distance from three days each course of treatment.
3, diagnosis is differentiated:
(1) difficulty falling asleep.Refer to that dropping asleep latency prolongs (being longer than 30 minutes).
(2) sleep disorder.The finger awakening time is increased (every night above 30 minutes); Reduce the actual length of one's sleep (less than is 6 hours every night); The awakening time accounts for the length of one's sleep more than 10%.
(3) the sleep table is shallow.The 3-4 phase that refers to the NREM sleep is visited the minimizing of sleeping, and 10% of not enough sleep total time, the minimizing of REM sleep ratio shows that also Depth of sleep is not enough.
(4) early awakening.The sleep time of having waken up has waken up 30 minutes in advance time more normally.
(5) do not have enough sleep.Refer generally to adult sleep total time less than 6 hours, or Sleep efficiency (being the ratio of sleeping full night total time and writing time)≤80%.In teenager<90% and middle-aged and elderly people<65% be the standard of not having enough sleep.Generally speaking, whether do not have enough sleep, also should combine the patient at ordinary times sleep habit and daytime subjective symptoms and decide.
(6) Sleep architecture imbalance: mainly refer to NREM/REM sleep cycle<3 time and (or) the NREM/REM ratio length of one's sleep is not normal.
4, criterion of therapeutical effect: curative effect determinate standard--State Administration of Traditional Chinese Medicine " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ".Clinical recovery: sleep is normal, and the length of one's sleep, simultaneous phenomenon disappeared more than 6 hours.Effectively: total sleep time prolonged more than 2 hours, but less than 6 hours, simultaneous phenomenon improves.Invalid: before sleeping as taking medicine, or prolonged less than the length of one's sleep 2 hours, symptom does not have improvement.
5, therapeutic outcome: the present invention treats 60 examples, takes medicine three courses of treatment clinical recovery 17 examples, effective 39 examples, invalid 4 examples, cure rate 28%, effective percentage 65%, inefficiency 7%, total effective rate 93%.
Typical case's case therapeutic outcome
1, sex: the man, at 32 years old age, 2 years causes are often surfed the Net the late into the night and are directed at insomnia more than 2 years; Every night by food a slice clonazepam and mirtazapine half sheet just can be slept two or three hours and be dream entirely, it is very weak that the present health that do not know why becomes now, and performance is afraid of cold; Inappetence, hyperhidrosis loses weight; Also begin to occur headache, symptoms such as stomachache.
2, sex: the woman, at 48 years old age, the state of an illness is described: dizzy insomnia.Early 2 of 87 accidental chambers of heart beating, Color Sonography is normal, cervical vertebra c3,6 intervertebrals are to the outstanding dura mater leading edge pressurized in dead astern, and the neck marrow is no abnormal, and bilateral canalis vertebrarterialis symmetry is the normal flow spacing wave and once treated situation and effect; Traction massage 1 month is had an injection 5 days to no effect.
3, sex: the woman, at 37 years old age, the state of an illness is described: nearly 3 years of once intermittent insomnia all can continue one to three months at every turn; Eat of the Chinese patent medicine of Cure for insomnia, like GUIPI WAN, Tianwang Buxin Dan, ANSHEN BUXIN WAN; Join melatonin and all can take a turn for the better, saw that Henan one tame hospital said that Cure for insomnia has good method June last year on the net, can try out earlier, this medicine on probation of result eaten less than half an hour just dark sleepy; Feel, eaten after the drug withdrawal in ten days that sleeping time in an ensuing week is altogether less than ten hours all day with regard to serious insomnia with regard to sleepy, and depressed; The mood dysphoria is prone to enrage, even cries and screams, and the conditioning a period of time that takes traditional Chinese medicine afterwards is this, and there is a change for the better; But it is bad always to sleep, and all fears every evening can't fall asleep, and can't fall asleep so more more, and daytime, spirit was very poor; Emotion is also bad, and long-term a nearest old docter of TCM press disarmony between the heart and kidney and treats like this not as good as in the dust if just keep in mind, usefulness be Chinese goldthread colla corii asini decoction; Having taken falls asleep evening a period of time had not resembled former difficulty so, still felt to sleep badly, was prone to wake up with a start, and how to do thing laboriously daytime again; Feel to ache on one's body after wakeing up,, do not loosen, the sensation of sleepy feel never like think that muscle is tightly drawn always.
4, sex: the woman, the age: 42, because of irriate, feel bad and frighten the bad early awakening of sleep 15 years, beginning heart most has uncomfortable in chestly, breathes hard; Early rich symptom is perspired, and does not take notice of very much that these several years serious in the past, mainly is that cardia has constriction, the weight sense; Uncomfortable in chest, painful, the most serious is to lie awake all night, and tight with regard to heart one when just will fall asleep, and one fiber crops just wake up with a start scalp; Psychology fear and, done electrocardio, electroencephalogram, color ultra, also have ambulatory electrocardiogram all out of question.
Above four-player is through the treatment of my institute, and early, late twice (medicine) being taken before meal decoction of the present invention, each oral one bag, 10 days is a course of treatment, and each course of treatment is at a distance from three days, all fully recovers after taking three courses of treatment of the present invention continuously.