CN102813791B - Traditional Chinese medicine composition for treating kidney stone - Google Patents
Traditional Chinese medicine composition for treating kidney stone Download PDFInfo
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- CN102813791B CN102813791B CN201210270730.4A CN201210270730A CN102813791B CN 102813791 B CN102813791 B CN 102813791B CN 201210270730 A CN201210270730 A CN 201210270730A CN 102813791 B CN102813791 B CN 102813791B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating kidney stone. The traditional Chinese medicine composition for treating kidney stone comprises: by weight, 10 to 20 parts of poria, 5 to 15 parts of largehead atractylodes rhizome, 10 to 20 parts of cortex magnoliae officinalis, 10 to 20 parts of eucommia, 10 to 15 parts of Chinese yam, 5 to 15 parts of China dodder, 10 to 30 parts of christina loosestrife, 10 to 30 parts of Japanese climbing fern spore, 10 to 20 parts of endothelium corneum gigeriae galli, 10 to 30 parts of polygonum aviculare, 5 to 15 parts of cape jasmine fruit, 5 to 15 parts of weeping forsythia capsule, 10 to 20 parts of Jianqu and 5 to 10 parts of licorice. The traditional Chinese medicine composition for treating kidney stone has dual effects of qi-tonifying kidney-tonifying urinary calculus-removal and dampness-removal stranguria-treatment urinary calculus-removal, can realize thorough treatment on kidney stone and prevention of recurrence of calculus according to pathogenesis of kidney deficiency and kidney damp heat of patients with kidney stones, has a reasonable formula, clear treatment effects and small toxic or side effects, and is prepared from the traditional Chinese medicine raw materials having wide sources and low costs.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition that is used for the treatment of renal calculus.
Background technology
China's urinary system calculus sickness rate is 1%～5%, and urinary system calculus comprises renal calculus, ureteral calculus, vesical calculus and calculus of urethra.The cause of disease of urinary system calculus is very complicated, and it is relevant with the illness of natural environment, social condition, general metabolic disturbance and urinary system itself.
Got the application of the minimally-invasive treatment such as stone though have in recent years extracorporeal shock-wave lithotripsy (ESWL) and some non-open operations, make a lot of former miseries that need the patient of open surgery treatment to exempt open surgery, but the problem that after renal calculus operative treatment, relapse rate is high is perplexing Urology Surgery doctor all the time, from traditional Chinese medical science angle, it is controlled and can only take stopgap measures, be difficult to reach the object of effecting a permanent cure, and renal calculus operative treatment has certain indication, also there is certain complication, as: induced renal damage, postoperative fever, wound infection, septicemia, postoperative hemorrhage etc.And Chinese medicine has unique organic conception, a large amount of clinical researches has proved that Chinese medicine has unique advantage aspect treatment stranguria caused by urinary stone.Chinese medicine has in treatment renal calculus that curative effect is obvious, cheap, the feature such as have no side effect, and has made up operation, external stone crushing to microlith and muddy stone weak effect or invalid defect.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of renal calculus.
The technical solution adopted in the present invention is as follows: a kind of Chinese medicine composition that is used for the treatment of renal calculus, and this Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight:
10～20 parts of Poria, 5～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Cortex Magnoliae Officinalis, 10～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 5～15 parts of Semen Cuscutae, 10～30 parts of Herba Lysimachiaes, 10～30 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 10～20 10～30 parts of Fen, Herba Polygoni Avicularis, 5～15 parts of Fructus Gardeniaes, 5～15 parts of Fructus Forsythiaes, 10～20 parts of Massa Medicata Fermentata, 5～10 parts, Radix Glycyrrhizae.
Preferably, the Chinese medicine composition of described treatment renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
15 parts of Poria, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Cortex Magnoliae Officinalis, 15 parts of the Cortexs Eucommiae, 12 parts of Rhizoma Dioscoreaes, 10 parts of Semen Cuscutae, 20 parts of Herba Lysimachiaes, 20 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 15 20 parts of Fen, Herba Polygoni Avicularis, 10 parts of Fructus Gardeniaes, 10 parts of Fructus Forsythiaes, 15 parts of Massa Medicata Fermentata, 6 parts, Radix Glycyrrhizae.
Above-mentioned Chinese medicine composition routinely decocting method is directly taken after making decoction, also can get each raw material of Chinese medicine by formulation weight umber adds water and decocts 3 times, each 2 hours, collecting decoction, after filtration, being condensed into relative density is that 1.1～1.4(water content is 40%-60%) soft material, add 2～4 times of excipient, then after drying and crushing, pack into and in capsulae vacuus, make capsule.Powder, tablet that the dosage form of above-mentioned Chinese medicine composition can be made according to 2010 editions requirements of Chinese Pharmacopoeia.
Clinical test results is as follows:
(1), physical data
Inclusive criteria: waist Ji Shen district or lower abdominal pain discomfort, frequent micturition, urgent micturition, dysurea, be diagnosed as renal calculus through B-ultrasonic renal, x-ray or radiography; Calculus diameter is less than 10mm; Normal renal function; Calculus is following without urinary tract obstruction.Get rid of allergic constitution person, gestation or women breast-feeding their children and have the disease patients such as serious Liver and kidney, hemopoietic system.Selected 55 examples altogether, wherein male's 30 examples, women's 25 examples, age 18-60 year.
(2), research method
The selected patient of 55 example is divided into two groups, treatment group 27 examples, matched group 28 examples.
Treatment group: take Chinese medicine composition of the present invention (by the decoction making described in embodiment 1), every day, potion, took at twice, and drink water more than 1500ml every day.
Matched group: oral urinary calculi is logical, three times on the one each 4 grams, drink water more than 1500ml every day.
Two groups of patients drink more water and do more jumping exercise during treating, and pain person gives Anisodamine 5～10mg intramuscular injection or oral, merge urinary system infection person and add with antibiotic, and be 30 days the course for the treatment of.
(3), curative effect determinate standard
Recovery from illness: symptom and sign disappears, and naked eyes are shown in discharge sandstone, B ultrasonic and abdomen plain film check that kidney, ureter, bladder are normal.Take a turn for the better: symptom and sign disappears, and B ultrasonic and the inspection of abdomen plain film are shown in that calculus moves down or diminishes.Invalid: symptom and sign and inspection are not improved.
(4), result of study
Treat after 30 days two groups of curative effect comparisons:
。
Note: through Radit inspection, P <0.05
(5), conclusion
Treat after 30 days, the total effective rate for the treatment of group is 89%, is significantly higher than the 78%(P<0.05 of matched group).Take Chinese medicine composition of the present invention and do not occur the untoward reaction such as hepatic and renal function injure, show that Chinese medicine composition of the present invention has good safety.
Herba Lysimachiae, Spora Lygodii, Endothelium Corneum Gigeriae Galli, Herba Polygoni Avicularis in the present invention's formula is the classical prescription of calculus removing, there is inducing diuresis for treating stranguria syndrome, change effect of hard Sal Nitri and pain relieving, be aided with the invigorating vital QI components such as Poria, Cortex Magnoliae Officinalis, the Cortex Eucommiae, Radix Glycyrrhizae, make the present invention there is vital energy benefiting and the kidney invigorating calculus and dampness removing Tonglin Paishi double effects, suffer from a deficiency of the kidney and warm two aspect etiology and pathogenesis for renal calculus patient, can fundamentally treat the recurrence of renal calculus and prevention calculus, be particularly useful for that microlith is not discharged in a short time or calculus below 8mm and renal function is good and without the patient who obviously infects.
Formula of the present invention rationally, determined curative effect, toxic and side effects be little, the raw material of Chinese medicine wide material sources that use in formula, with low cost.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine composition that is used for the treatment of renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
15 grams of Poria, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Cortex Magnoliae Officinalis, 18 grams of the Cortexs Eucommiae, 14 grams of Rhizoma Dioscoreaes, 10 grams of Semen Cuscutae, 15 grams of Herba Lysimachiaes, 10 grams of Spora Lygodii, Endothelium Corneum Gigeriae Galli 16 20 grams of Ke, Herba Polygoni Avicularis, 10 grams of Fructus Gardeniaes, 5 grams of Fructus Forsythiaes, 15 grams of Massa Medicata Fermentata, 6 grams, Radix Glycyrrhizae.Preparation method is: get each raw material of Chinese medicine by above-mentioned weight and add after decocting to obtain the about 300ml of medicinal liquid, make decoction, 1 dose of every day, points 2 times oral.
Embodiment 2
A kind of Chinese medicine composition that is used for the treatment of renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
18 grams of Poria, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Cortex Magnoliae Officinalis, 20 grams of the Cortexs Eucommiae, 10 grams of Rhizoma Dioscoreaes, 15 grams of Semen Cuscutae, 25 grams of Herba Lysimachiaes, 20 grams of Spora Lygodii, Endothelium Corneum Gigeriae Galli 10 10 grams of Ke, Herba Polygoni Avicularis, 5 grams of Fructus Gardeniaes, 10 grams of Fructus Forsythiaes, 10 grams of Massa Medicata Fermentata, 8 grams, Radix Glycyrrhizae.Preparation method is: get each raw material of Chinese medicine by above-mentioned weight and add water and decoct 3 times, each 2 hours, collecting decoction, after filtration, be condensed into the soft material of relative density 1.2, add 3 times of excipient (dextrin and sucrose, weight ratio is 1:2), then after drying and crushing, fill capsulae vacuus and obtain Chinese medicinal composition capsules agent of the present invention (0.3 gram /), instructions of taking is 3 times on the one, each 3.
Embodiment 3
A kind of Chinese medicine composition that is used for the treatment of renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
20 grams of Poria, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 16 grams of Cortex Magnoliae Officinalis, 10 grams of the Cortexs Eucommiae, 15 grams of Rhizoma Dioscoreaes, 5 grams of Semen Cuscutae, 30 grams of Herba Lysimachiaes, 25 grams of Spora Lygodii, Endothelium Corneum Gigeriae Galli 15 30 grams of Ke, Herba Polygoni Avicularis, 12 grams of Fructus Gardeniaes, 15 grams of Fructus Forsythiaes, 20 grams of Massa Medicata Fermentata, 10 grams, Radix Glycyrrhizae.Preparation method is: get each raw material of Chinese medicine by above-mentioned weight and be crushed to 120 object fine powders, make powder.
Embodiment 4
A kind of Chinese medicine composition that is used for the treatment of renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
10 grams of Poria, 5 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Cortex Magnoliae Officinalis, 15 grams of the Cortexs Eucommiae, 12 grams of Rhizoma Dioscoreaes, 8 grams of Semen Cuscutae, 20 grams of Herba Lysimachiaes, 30 grams of Spora Lygodii, Endothelium Corneum Gigeriae Galli 20 25 grams of Ke, Herba Polygoni Avicularis, 15 grams of Fructus Gardeniaes, 12 grams of Fructus Forsythiaes, 10 grams of Massa Medicata Fermentata, 5 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, crushing fine powder, adds adjuvant to make tablet.
Model case 1: Mr. Gao, 53 years old, occurred the left lumbar region angor without obvious inducement before 1 year, spontaneous remission after a few hours, without heating, nauseating, vomiting, left side renal calculus is found in ultrasound diagnosis, give remission after medicine lithagogue treatment, once, check B ultrasonic shows left side renal calculus (3mm × 4mm), takes capsule of the present invention in rear approximately outbreak in 3 months, 3 times on the one, each 3, and advise every daily drink 2000ml and do jumping exercise more, after 30 days, check B ultrasonic and show that left side renal calculus disappears.
Model case 2: Mr. Wang, 22 years old, before one month, there is right side waist and belly paroxysmal pain without obvious inducement, time sharp ache occur hematuria, ultrasound diagnosis shows right Renal sinus separation, the strong echo of interior visible big or small about 7mm × 5mm group accompanying sound shadow, gives spasmolytic, pain relieving symptomatic treatment, takes capsule of the present invention, 3 times on the one, each 3, and advise every daily drink 2000ml and do jumping exercise more, after 30 days, check B ultrasonic and show that right side renal calculus disappears.
Claims (2)
1. be used for the treatment of a Chinese medicine composition for renal calculus, it is characterized in that this Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight: 10～20 parts of Poria, 5～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Cortex Magnoliae Officinalis, 10～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 5～15 parts of Semen Cuscutae, 10～30 parts of Herba Lysimachiaes, 10～30 parts of Spora Lygodii, 10～20 parts of Endothelium Corneum Gigeriae Galli, 10～30 parts of Herba Polygoni Avicularis, 5～15 parts of Fructus Gardeniaes, 5～15 parts of Fructus Forsythiaes, 10～20 parts of Massa Medicata Fermentata, 5～10 parts, Radix Glycyrrhizae.
2. according to a kind of Chinese medicine composition that is used for the treatment of renal calculus claimed in claim 1, it is characterized in that the parts by weight of described Chinese medicine composition are as follows: 15～20 parts of Poria, 10～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～15 parts of Cortex Magnoliae Officinalis, 15～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 10～15 parts of Semen Cuscutae, 20～30 parts of Herba Lysimachiaes, 20～30 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 15～20 20～30 parts of Fen, Herba Polygoni Avicularis, 10～15 parts of Fructus Gardeniaes, 10～15 parts of Fructus Forsythiaes, 15～20 parts of Massa Medicata Fermentata, 5～10 parts, Radix Glycyrrhizae.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103251684B (en) * | 2013-06-09 | 2014-09-03 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
| CN103566132A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating urolithiasis |
| CN103566133A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating kidney stone |
| CN104547428A (en) * | 2014-04-06 | 2015-04-29 | 王颖慧 | Traditional Chinese medicine for treating early renal calculus accompanied by waist and knee pain |
| CN105497163A (en) * | 2014-09-27 | 2016-04-20 | 卢雨萍 | Traditional Chinese medicine formula for treating kidney stone |
| CN104857091A (en) * | 2015-06-03 | 2015-08-26 | 广西大学 | Traditional Chinese medicine composition for treating renal calculus |
| CN105560989A (en) * | 2016-01-11 | 2016-05-11 | 郭峰 | Traditional Chinese medicine composition for treating renal calculus and urethral calculus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1554413A (en) * | 2003-12-26 | 2004-12-15 | 喻建平 | Chinese medicine for treating urolithiasis and its preparing method |
| CN1895628A (en) * | 2006-06-12 | 2007-01-17 | 费春华 | Traditional Chinese medicine composition for treating calculus |
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| CN1065134C (en) * | 1998-07-13 | 2001-05-02 | 戴伸柱 | Quick-acting preparation for litholysis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1554413A (en) * | 2003-12-26 | 2004-12-15 | 喻建平 | Chinese medicine for treating urolithiasis and its preparing method |
| CN1895628A (en) * | 2006-06-12 | 2007-01-17 | 费春华 | Traditional Chinese medicine composition for treating calculus |
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