CN102813791A - Traditional Chinese medicine composition for treating kidney stone - Google Patents
Traditional Chinese medicine composition for treating kidney stone Download PDFInfo
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- CN102813791A CN102813791A CN2012102707304A CN201210270730A CN102813791A CN 102813791 A CN102813791 A CN 102813791A CN 2012102707304 A CN2012102707304 A CN 2012102707304A CN 201210270730 A CN201210270730 A CN 201210270730A CN 102813791 A CN102813791 A CN 102813791A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating kidney stone. The traditional Chinese medicine composition for treating kidney stone comprises: by weight, 10 to 20 parts of poria, 5 to 15 parts of largehead atractylodes rhizome, 10 to 20 parts of cortex magnoliae officinalis, 10 to 20 parts of eucommia, 10 to 15 parts of Chinese yam, 5 to 15 parts of China dodder, 10 to 30 parts of christina loosestrife, 10 to 30 parts of Japanese climbing fern spore, 10 to 20 parts of endothelium corneum gigeriae galli, 10 to 30 parts of polygonum aviculare, 5 to 15 parts of cape jasmine fruit, 5 to 15 parts of weeping forsythia capsule, 10 to 20 parts of Jianqu and 5 to 10 parts of licorice. The traditional Chinese medicine composition for treating kidney stone has dual effects of qi-tonifying kidney-tonifying urinary calculus-removal and dampness-removal stranguria-treatment urinary calculus-removal, can realize thorough treatment on kidney stone and prevention of recurrence of calculus according to pathogenesis of kidney deficiency and kidney damp heat of patients with kidney stones, has a reasonable formula, clear treatment effects and small toxic or side effects, and is prepared from the traditional Chinese medicine raw materials having wide sources and low costs.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition that is used to treat renal calculus.
Background technology
China's urinary system calculus sickness rate is 1%～5%, and urinary system calculus comprises renal calculus, ureteral calculus, vesical calculus and calculus of urethra.The cause of disease of urinary system calculus is very complicated, and it is relevant with the illness of natural environment, social condition, general metabolic disturbance and urinary system itself.
Though being arranged in recent years, ESWL and some non-open operations got the application of minimally-invasive treatment such as stone; Make a lot of former patients that need open surgery to treat exempt the misery of open surgery; But the problem that relapse rate is high behind the renal calculus operative treatment is perplexing the Urology Surgery doctor all the time, says from traditional Chinese medical science angle, and it is controlled and can only take stopgap measures; Be difficult to reach the purpose of effecting a permanent cure; And the renal calculus operative treatment has certain indication, and certain complication is also arranged, as: damage kidney, postoperative fever, wound infection, septicemia, postoperative hemorrhage etc.And Chinese medicine has unique organic conception, and vast amount of clinical has proved that Chinese medicine has special advantages aspect the treatment stranguria caused by urinary stone.Chinese medicine has obvious, cheap, the characteristics such as have no side effect of curative effect in treatment renal calculus, has remedied operation, external stone crushing to microlith and muddy stone weak effect or invalid defective.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition that is used to treat renal calculus.
The technical scheme that the present invention adopted is following: a kind of Chinese medicine composition that is used to treat renal calculus, and this Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight:
10～20 parts of Poria, 5～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Cortex Magnoliae Officinalis, 10～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 5～15 parts of Semen Cuscutae, 10～30 parts of Herba Lysimachiaes, 10～30 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 10～20 10～30 parts of Fen 、 Herba Polygoni Avicularis, 5～15 parts of Fructus Gardeniaes, 5～15 parts of Fructus Forsythiaes, 10～20 parts of Massa Medicata Fermentata, 5～10 parts in Radix Glycyrrhizae.
Preferably, the Chinese medicine composition of said treatment renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
15 parts of Poria, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Cortex Magnoliae Officinalis, 15 parts of the Cortexs Eucommiae, 12 parts of Rhizoma Dioscoreaes, 10 parts of Semen Cuscutae, 20 parts of Herba Lysimachiaes, 20 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 15 20 parts of Fen 、 Herba Polygoni Avicularis, 10 parts of Fructus Gardeniaes, 10 parts of Fructus Forsythiaes, 15 parts of Massa Medicata Fermentata, 6 parts in Radix Glycyrrhizae.
Above-mentioned Chinese medicine composition is directly taken after making decoction by conventional decocting method; Also can get each raw material of Chinese medicine by the formulation weight umber adds decocting and endures 3 times; Each 2 hours, collecting decoction, being condensed into relative density after the filtration is the soft material of 1.1～1.4 (water content is 40%-60%); Add 2～4 times of excipient, process capsule in the capsulae vacuus of packing into after the drying and crushing again.Powder, tablet that the dosage form of above-mentioned Chinese medicine composition can be processed according to 2010 editions requirements of Chinese Pharmacopoeia.
Clinical test results is following:
(1), physical data
Include standard in: waist and kidney district or lower abdominal pain are uncomfortable, and frequent micturition, urgent micturition, dysurea are diagnosed as renal calculus through kidney B ultrasonic, X line or radiography; The calculus diameter is less than 10mm; Renal function is normal; No urinary tract obstruction below the calculus.Get rid of allergic constitution person, gestation or women breast-feeding their children and disease patients such as serious Liver and kidney, hemopoietic system are arranged.Selected altogether 55 examples, male's 30 examples wherein, women's 25 examples, age 18-60 year.
(2), research method
The selected patient of 55 examples is divided into two groups, and 27 examples are organized in treatment, matched group 28 examples.
The treatment group: take Chinese medicine composition of the present invention (by the embodiment 1 said decoction that makes), every day, potion was taken at twice, and drink water more than the 1500ml every day.
Matched group: oral urinary calculi is logical, three times on the one each 4 grams, and drink water more than the 1500ml every day.
Two groups of patients polydipsia water and do jumping exercise during treating more, pain person gives Anisodamine 5～10mg intramuscular injection or oral, and merging urinary system infection person adds and uses antibiotic, and be 30 days the course of treatment.
(3), curative effect determinate standard
Recovery from illness: symptom and sign disappears, and naked eyes are seen the discharge sandstone, and B ultrasonic and abdomen plain film inspection kidney, ureter, bladder are normal.Take a turn for the better: symptom and sign disappears, and B ultrasonic and the inspection of abdomen plain film see that calculus moves down or diminishes.Invalid: symptom and sign and inspection do not have obviously improvement.
(4), result of study
Treat after 30 days, two groups of curative effects compare:
。
Annotate: through the Radit check, P < 0.05
(5), conclusion
Treat after 30 days, the total effective rate of treatment group is 89%, is significantly higher than 78% (P < 0.05) of matched group.Take Chinese medicine composition of the present invention and untoward reaction such as hepatic and renal function injure do not occur, show that Chinese medicine composition of the present invention has safety preferably.
Herba Lysimachiae, Spora Lygodii, Endothelium Corneum Gigeriae Galli 、 Herba Polygoni Avicularis in the present invention's prescription is the classical prescription of urinary calculus removing; Effect with inducing diuresis for treating stranguria syndrome, the hard Sal Nitri of change and pain relieving; Be aided with invigorating vital QI components such as Poria, Cortex Magnoliae Officinalis, the Cortex Eucommiae, Radix Glycyrrhizae; Make the present invention have vital energy benefiting and the kidney invigorating calculus and dampness removing Tonglin Paishi double effects; Suffer from a deficiency of the kidney and warm two aspect etiology and pathogenesis to the renal calculus patient, can fundamentally treat the recurrence of renal calculus and prevention calculus, be particularly useful for that microlith is not discharged in a short time or calculus below 8mm and renal function is good and do not have a patient who obviously infects.
Prescription of the present invention rationally, determined curative effect, toxic and side effects be little, the raw material of Chinese medicine wide material sources that use in the prescription, with low cost.
The specific embodiment
Embodiment 1
A kind of Chinese medicine composition that is used to treat renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
Poria 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Cortex Magnoliae Officinalis 15 grams, the Cortex Eucommiae 18 grams, Rhizoma Dioscoreae 14 grams, Semen Cuscutae 10 grams, Herba Lysimachiae 15 grams, Spora Lygodii 10 grams, Endothelium Corneum Gigeriae Galli 16 Ke 、 Herba Polygoni Avicularis 20 grams, Fructus Gardeniae 10 grams, Fructus Forsythiae 5 grams, Massa Medicata Fermentata 15 grams, Radix Glycyrrhizae 6 grams.Method for preparing is: by above-mentioned weight get each raw material of Chinese medicine add behind the decocting the about 300ml of medicinal liquid, make decoction, 1 dose of every day, divide 2 times oral.
Embodiment 2
A kind of Chinese medicine composition that is used to treat renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
Poria 18 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Cortex Magnoliae Officinalis 20 grams, the Cortex Eucommiae 20 grams, Rhizoma Dioscoreae 10 grams, Semen Cuscutae 15 grams, Herba Lysimachiae 25 grams, Spora Lygodii 20 grams, Endothelium Corneum Gigeriae Galli 10 Ke 、 Herba Polygoni Avicularis 10 grams, Fructus Gardeniae 5 grams, Fructus Forsythiae 10 grams, Massa Medicata Fermentata 10 grams, Radix Glycyrrhizae 8 grams.Method for preparing is: gets each raw material of Chinese medicine by above-mentioned weight and adds decocting and endure 3 times, and each 2 hours, collecting decoction; Be condensed into the soft material of relative density 1.2 after the filtration; Add 3 times of excipient (dextrin and sucrose, weight ratio are 1:2), the dress capsulae vacuus promptly gets Chinese medicinal composition capsules agent of the present invention (0.3 gram/grain) after the drying and crushing again; Instructions of taking is 3 times on the one, each 3.
Embodiment 3
A kind of Chinese medicine composition that is used to treat renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
Poria 20 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Cortex Magnoliae Officinalis 16 grams, the Cortex Eucommiae 10 grams, Rhizoma Dioscoreae 15 grams, Semen Cuscutae 5 grams, Herba Lysimachiae 30 grams, Spora Lygodii 25 grams, Endothelium Corneum Gigeriae Galli 15 Ke 、 Herba Polygoni Avicularis 30 grams, Fructus Gardeniae 12 grams, Fructus Forsythiae 15 grams, Massa Medicata Fermentata 20 grams, Radix Glycyrrhizae 10 grams.Method for preparing is: get each raw material of Chinese medicine by above-mentioned weight and be crushed to 120 purpose fine powders, make powder.
Embodiment 4
A kind of Chinese medicine composition that is used to treat renal calculus is made up of the raw material of Chinese medicine of following portions by weight:
Poria 10 grams, the Rhizoma Atractylodis Macrocephalae 5 grams, Cortex Magnoliae Officinalis 10 grams, the Cortex Eucommiae 15 grams, Rhizoma Dioscoreae 12 grams, Semen Cuscutae 8 grams, Herba Lysimachiae 20 grams, Spora Lygodii 30 grams, Endothelium Corneum Gigeriae Galli 20 Ke 、 Herba Polygoni Avicularis 25 grams, Fructus Gardeniae 15 grams, Fructus Forsythiae 12 grams, Massa Medicata Fermentata 10 grams, Radix Glycyrrhizae 5 grams.Method for preparing is: get each tcm components raw material by above-mentioned parts by weight, crushing fine powder adds adjuvant and processes tablet.
Model case 1: Mr. Gao, 53 years old, the left lumbar region angor of the no obvious inducement of appearance before 1 year, spontaneous remission after several hours; Do not have heating, feel sick, vomiting, left side renal calculus is found in ultrasound diagnosis, gives remission behind the medicine lithagogue treatment, back outbreak in about 3 months once; The check B ultrasonic shows left side renal calculus (3mm * 4mm), take capsule of the present invention, 3 times on the one; Each 3, and advise and drink water 2000ml every day and do jumping exercise more, the check B ultrasonic shows that left side renal calculus disappears after 30 days.
Model case 2: Mr. Wang, 22 years old, right side waist and belly paroxysmal pain appearred in no obvious inducement before one month; The time sharp ache and hematuria occurs, ultrasound diagnosis shows that right sinus renalis separates, the strong echo of the interior about 7mm * 5mm of visible size is rolled into a ball the accompanying sound shadow; Give spasmolytic, pain relieving symptomatic treatment, take capsule of the present invention, 3 times on the one; Each 3, and advise and drink water 2000ml every day and do jumping exercise more, the check B ultrasonic shows that right side renal calculus disappears after 30 days.
Claims (2)
1. Chinese medicine composition that is used to treat renal calculus is characterized in that this Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight: 10～20 parts of Poria, 5～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～20 parts of Cortex Magnoliae Officinalis, 10～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 5～15 parts of Semen Cuscutae, 10～30 parts of Herba Lysimachiaes, 10～30 parts of Spora Lygodii, 10～20 parts of Endothelium Corneum Gigeriae Galli, 10～30 parts of Herba Polygoni Avicularis, 5～15 parts of Fructus Gardeniaes, 5～15 parts of Fructus Forsythiaes, 10～20 parts of Massa Medicata Fermentata, 5～10 parts in Radix Glycyrrhizae.
2. according to the described a kind of Chinese medicine composition that is used to treat renal calculus of claim 1, it is characterized in that the parts by weight of said Chinese medicine composition are following: 15～20 parts of Poria, 10～15 parts of the Rhizoma Atractylodis Macrocephalaes, 10～15 parts of Cortex Magnoliae Officinalis, 15～20 parts of the Cortexs Eucommiae, 10～15 parts of Rhizoma Dioscoreaes, 10～15 parts of Semen Cuscutae, 20～30 parts of Herba Lysimachiaes, 20～30 parts of Spora Lygodii, Endothelium Corneum Gigeriae Galli 15～20 20～30 parts of Fen 、 Herba Polygoni Avicularis, 10～15 parts of Fructus Gardeniaes, 10～15 parts of Fructus Forsythiaes, 15～20 parts of Massa Medicata Fermentata, 5～10 parts in Radix Glycyrrhizae.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210270730.4A CN102813791B (en) | 2012-08-01 | 2012-08-01 | Traditional Chinese medicine composition for treating kidney stone |
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| CN201210270730.4A CN102813791B (en) | 2012-08-01 | 2012-08-01 | Traditional Chinese medicine composition for treating kidney stone |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251684A (en) * | 2013-06-09 | 2013-08-21 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
| CN103566133A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating kidney stone |
| CN103566132A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating urolithiasis |
| CN104547428A (en) * | 2014-04-06 | 2015-04-29 | 王颖慧 | Traditional Chinese medicine for treating early renal calculus accompanied by waist and knee pain |
| CN104857091A (en) * | 2015-06-03 | 2015-08-26 | 广西大学 | Traditional Chinese medicine composition for treating renal calculus |
| CN105497163A (en) * | 2014-09-27 | 2016-04-20 | 卢雨萍 | Traditional Chinese medicine formula for treating kidney stone |
| CN105560989A (en) * | 2016-01-11 | 2016-05-11 | 郭峰 | Traditional Chinese medicine composition for treating renal calculus and urethral calculus |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1223136A (en) * | 1998-07-13 | 1999-07-21 | 戴伸柱 | Quick-acting preparation for litholysis |
| CN1554413A (en) * | 2003-12-26 | 2004-12-15 | 喻建平 | Chinese medicine for treating urolithiasis and its preparing method |
| CN1895628A (en) * | 2006-06-12 | 2007-01-17 | 费春华 | Traditional Chinese medicine composition for treating calculus |
-
2012
- 2012-08-01 CN CN201210270730.4A patent/CN102813791B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1223136A (en) * | 1998-07-13 | 1999-07-21 | 戴伸柱 | Quick-acting preparation for litholysis |
| CN1554413A (en) * | 2003-12-26 | 2004-12-15 | 喻建平 | Chinese medicine for treating urolithiasis and its preparing method |
| CN1895628A (en) * | 2006-06-12 | 2007-01-17 | 费春华 | Traditional Chinese medicine composition for treating calculus |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251684A (en) * | 2013-06-09 | 2013-08-21 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
| CN103251684B (en) * | 2013-06-09 | 2014-09-03 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
| CN103566133A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating kidney stone |
| CN103566132A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating urolithiasis |
| CN104547428A (en) * | 2014-04-06 | 2015-04-29 | 王颖慧 | Traditional Chinese medicine for treating early renal calculus accompanied by waist and knee pain |
| CN105497163A (en) * | 2014-09-27 | 2016-04-20 | 卢雨萍 | Traditional Chinese medicine formula for treating kidney stone |
| CN104857091A (en) * | 2015-06-03 | 2015-08-26 | 广西大学 | Traditional Chinese medicine composition for treating renal calculus |
| CN105560989A (en) * | 2016-01-11 | 2016-05-11 | 郭峰 | Traditional Chinese medicine composition for treating renal calculus and urethral calculus |
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| CN102813791B (en) | 2014-11-05 |
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