CN102805091A - Bactericidal composition and preparation thereof - Google Patents
Bactericidal composition and preparation thereof Download PDFInfo
- Publication number
- CN102805091A CN102805091A CN2012103019848A CN201210301984A CN102805091A CN 102805091 A CN102805091 A CN 102805091A CN 2012103019848 A CN2012103019848 A CN 2012103019848A CN 201210301984 A CN201210301984 A CN 201210301984A CN 102805091 A CN102805091 A CN 102805091A
- Authority
- CN
- China
- Prior art keywords
- bactericidal composition
- pyraclostrobin
- bactericide
- fluoxastrobin
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 63
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000005869 Pyraclostrobin Substances 0.000 claims abstract description 42
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000003899 bactericide agent Substances 0.000 claims abstract description 31
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims abstract description 16
- 239000005784 Fluoxastrobin Substances 0.000 claims description 36
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 claims description 36
- 239000000839 emulsion Substances 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 12
- 239000000375 suspending agent Substances 0.000 claims description 12
- 239000000725 suspension Substances 0.000 claims description 12
- 239000004562 water dispersible granule Substances 0.000 claims description 12
- 238000009736 wetting Methods 0.000 claims description 12
- 208000031968 Cadaver Diseases 0.000 claims description 3
- 230000000361 pesticidal effect Effects 0.000 claims description 3
- 201000010099 disease Diseases 0.000 abstract description 15
- 230000000295 complement effect Effects 0.000 abstract description 10
- 230000002195 synergetic effect Effects 0.000 abstract description 10
- 239000005730 Azoxystrobin Substances 0.000 abstract description 8
- WFDXOXNFNRHQEC-GHRIWEEISA-N azoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=CC(OC=2C(=CC=CC=2)C#N)=NC=N1 WFDXOXNFNRHQEC-GHRIWEEISA-N 0.000 abstract description 7
- 239000000575 pesticide Substances 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract description 2
- 230000002265 prevention Effects 0.000 abstract 2
- 230000003111 delayed effect Effects 0.000 abstract 1
- 238000003912 environmental pollution Methods 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 22
- 230000000694 effects Effects 0.000 description 15
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 12
- 239000000080 wetting agent Substances 0.000 description 12
- -1 polyethylene Polymers 0.000 description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 description 9
- 238000002156 mixing Methods 0.000 description 9
- 239000007859 condensation product Substances 0.000 description 8
- 239000002270 dispersing agent Substances 0.000 description 8
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 8
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 7
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 7
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 7
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 229920001285 xanthan gum Polymers 0.000 description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 230000000855 fungicidal effect Effects 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 5
- 240000007594 Oryza sativa Species 0.000 description 5
- 235000007164 Oryza sativa Nutrition 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 5
- 125000003282 alkyl amino group Chemical group 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 235000014113 dietary fatty acids Nutrition 0.000 description 5
- 239000000194 fatty acid Substances 0.000 description 5
- 229930195729 fatty acid Natural products 0.000 description 5
- 244000000010 microbial pathogen Species 0.000 description 5
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 5
- 229920000573 polyethylene Polymers 0.000 description 5
- 235000009566 rice Nutrition 0.000 description 5
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 5
- 229940104261 taurate Drugs 0.000 description 5
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 5
- XVVZSEXTAACTPS-UHFFFAOYSA-N 5-[hydroxy-(4-nitrophenoxy)phosphoryl]pentanoic acid Chemical compound OC(=O)CCCCP(O)(=O)OC1=CC=C([N+]([O-])=O)C=C1 XVVZSEXTAACTPS-UHFFFAOYSA-N 0.000 description 4
- 239000005995 Aluminium silicate Substances 0.000 description 4
- JISVRKSRAKIYPZ-UHFFFAOYSA-N C=O.C1(=CC=CC2=CC=CC=C12)S(=O)(=O)OCOS(=O)(=O)C1=CC=CC2=CC=CC=C12.[Na] Chemical compound C=O.C1(=CC=CC2=CC=CC=C12)S(=O)(=O)OCOS(=O)(=O)C1=CC=CC2=CC=CC=C12.[Na] JISVRKSRAKIYPZ-UHFFFAOYSA-N 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 4
- 241000221785 Erysiphales Species 0.000 description 4
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 4
- 241000233679 Peronosporaceae Species 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
- 235000012211 aluminium silicate Nutrition 0.000 description 4
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical class N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 4
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 4
- 235000011130 ammonium sulphate Nutrition 0.000 description 4
- 125000000129 anionic group Chemical group 0.000 description 4
- 229920001400 block copolymer Polymers 0.000 description 4
- 229920005551 calcium lignosulfonate Polymers 0.000 description 4
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 4
- 239000004202 carbamide Chemical class 0.000 description 4
- 239000002131 composite material Substances 0.000 description 4
- 238000009833 condensation Methods 0.000 description 4
- 230000005494 condensation Effects 0.000 description 4
- 150000002191 fatty alcohols Chemical class 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 239000000417 fungicide Substances 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 description 4
- 229920001223 polyethylene glycol Polymers 0.000 description 4
- 229920000151 polyglycol Polymers 0.000 description 4
- 239000010695 polyglycol Substances 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 4
- 239000001488 sodium phosphate Substances 0.000 description 4
- 229910000162 sodium phosphate Inorganic materials 0.000 description 4
- 229910021653 sulphate ion Inorganic materials 0.000 description 4
- 230000009885 systemic effect Effects 0.000 description 4
- 239000013638 trimer Substances 0.000 description 4
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 239000004368 Modified starch Chemical class 0.000 description 3
- 229920000881 Modified starch Chemical class 0.000 description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical class [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000000440 bentonite Substances 0.000 description 3
- 229910000278 bentonite Inorganic materials 0.000 description 3
- 235000012216 bentonite Nutrition 0.000 description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical class O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 3
- 210000000481 breast Anatomy 0.000 description 3
- 235000013877 carbamide Nutrition 0.000 description 3
- 238000009313 farming Methods 0.000 description 3
- 238000000227 grinding Methods 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 3
- 239000011707 mineral Chemical class 0.000 description 3
- 235000010755 mineral Nutrition 0.000 description 3
- 235000019426 modified starch Nutrition 0.000 description 3
- 230000003449 preventive effect Effects 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000000741 silica gel Substances 0.000 description 3
- 229910002027 silica gel Inorganic materials 0.000 description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 3
- 229920001027 sodium carboxymethylcellulose Chemical class 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 2
- 235000017060 Arachis glabrata Nutrition 0.000 description 2
- 244000105624 Arachis hypogaea Species 0.000 description 2
- 235000010777 Arachis hypogaea Nutrition 0.000 description 2
- 235000018262 Arachis monticola Nutrition 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 102100025287 Cytochrome b Human genes 0.000 description 2
- 108010075028 Cytochromes b Proteins 0.000 description 2
- 241000233654 Oomycetes Species 0.000 description 2
- 206010039509 Scab Diseases 0.000 description 2
- 244000061456 Solanum tuberosum Species 0.000 description 2
- 235000002595 Solanum tuberosum Nutrition 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 description 2
- 240000006365 Vitis vinifera Species 0.000 description 2
- 235000014787 Vitis vinifera Nutrition 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000003905 agrochemical Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000004898 kneading Methods 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002438 mitochondrial effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 235000020232 peanut Nutrition 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000000661 sodium alginate Substances 0.000 description 2
- 235000010413 sodium alginate Nutrition 0.000 description 2
- 229940005550 sodium alginate Drugs 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- VMPHSYLJUKZBJJ-UHFFFAOYSA-N trilaurin Chemical compound CCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC VMPHSYLJUKZBJJ-UHFFFAOYSA-N 0.000 description 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 1
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000233652 Chytridiomycota Species 0.000 description 1
- PHEDXBVPIONUQT-UHFFFAOYSA-N Cocarcinogen A1 Natural products CCCCCCCCCCCCCC(=O)OC1C(C)C2(O)C3C=C(C)C(=O)C3(O)CC(CO)=CC2C2C1(OC(C)=O)C2(C)C PHEDXBVPIONUQT-UHFFFAOYSA-N 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 102100030497 Cytochrome c Human genes 0.000 description 1
- 108010075031 Cytochromes c Proteins 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 240000001987 Pyrus communis Species 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- JNVCSEDACVAATK-UHFFFAOYSA-L [Ca+2].[S-]SSS[S-] Chemical compound [Ca+2].[S-]SSS[S-] JNVCSEDACVAATK-UHFFFAOYSA-L 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 229940054066 benzamide antipsychotics Drugs 0.000 description 1
- 150000003936 benzamides Chemical class 0.000 description 1
- 230000031018 biological processes and functions Effects 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 229920006184 cellulose methylcellulose Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000013066 combination product Substances 0.000 description 1
- 229940127555 combination product Drugs 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229940125532 enzyme inhibitor Drugs 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of a pesticide preparation, and discloses a bactericidal composition. The bactericidal composition consists of pyraclostrobin and azoxystrobin, wherein the mass ratio of the pyraclostrobin to the azoxystrobin is 1:0.5-5. The invention also discloses a bactericide which consists of the bactericidal composition and auxiliary materials acceptable in pesticide preparations, wherein the bactericidal composition accounts for 1-90 percent by weight of the bactericide. According to the bactericidal composition and the preparation thereof, the pyraclostrobin and the azoxystrobin are compounded as an active ingredient, complement the advantages of each other and have a synergistic effect, so that the fungal resistance is delayed, the environmental pollution is reduced, and meanwhile, the bactericidal composition has a synergistic effect on prevention and treatment of crop diseases and can be widely applied to prevention and treatment of the crop diseases.
Description
Technical field
The present invention relates to the pesticidal preparations field, relate to a kind of bactericidal composition and preparation thereof specifically.
Background technology
Bactericide is the one type of agricultural chemicals that is used to prevent and treat the plant disease that is caused by various pathogenic microorganisms, on crops, use extensively, but the disease of using the agent of bactericide list to prevent and treat is more single, and is easy to generate resistance.Composite bactericide then can be prevented and treated multiple diseases, but also can delay the drug-fast generation of pathogenic microorganism.
Composite the using with of bactericide has a long history, and the lime sulfur that used as far back as 1821 has just begun when preventing and treating the pear tree disease.Along with the development of organic bactericide, the composite scope of using with of bactericide constantly enlarges, and the mixture kind is on the increase, and particularly developing rapidly of systemic fungicide more promoted the development of fungicide mixture.Its reason is not only the double needs of controlling two or more diseases in the plant protection, and is to delay the needs that systemic fungicide produces resistance.Simultaneously because the general more complicated of systemic fungicide structure, cost is than higher, and the bactericide of it and other types is used with and can be reduced drug cost.
Bactericide is used with; Normal change with biological action; Different fungicidal activity components mix each active component of back because the difference of composition, structure, physicochemical property makes that the synergy between each active component is typically expressed as synergistic effect, summation action or antagonism.In fact reasonably use with is exactly to select its useful biology to change, i.e. synergistic effect with the effect of receiving that single preparation is difficult to receive, reaches the purpose of better preventing and treating disease.
Fluoxastrobin, chemical name are (E)-[2-[6-(2-cyano-benzene oxygen) pyrimidine-4-base oxygen] phenyl]-3-methoxy-methyl acrylate, belong to methoxy acrylic bactericide.Methoxy acrylic bactericide has unique mechanism of action, and it stops the ATP of cell synthetic through the electronics transmission of pinning between cytochrome b and the c1, thereby restrains the pathogenic microorganism mitochondrial respiratory and bring into play bacteriostasis.It is effective to the bacterial strain that 14-demethoxylation enzyme inhibitor, benzamides, dicarboxylic dihydrazides amine and benzimidazole produce resistance, have protection, treat, root out, infiltration, systemic activity, and can be in plant corpus, degrade very soon in soil and the water.Efficient, the wide spectrum of Fluoxastrobin all has good activity to nearly all fungi steel (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti) disease such as powdery mildew, rust, glume blight, net blotch, downy mildew, rice blast etc.Can be used for cauline leaf spraying, seed treatment, also can carry out soil treatment, be mainly used in cereal, paddy rice, peanut, grape, potato, fruit tree, vegetables, coffee, lawn etc.
Bactericide can be protected the growth of crops better efficiently; And the control efficiency of Fluoxastrobin can't farthest protect crops not receive the infringement of pathogenic microorganism; And use Fluoxastrobin also to be prone to produce resistance for a long time; Therefore a kind of bactericidal composition novel, that have higher control efficiency need be provided, so that cover crop avoids the infringement of pathogenic microorganism better.
Summary of the invention
In view of this; The object of the invention provides a kind of bactericidal composition and preparation thereof; Make the present composition and preparation thereof can improve the preventive effect to diseases such as anthracnose, climing rot, downy mildew, powdery mildew, leaf spot, scab, rust, glume blight, net blotch, rice blast, no cross tolerance.
For realizing the object of the invention, the present invention adopts following technical scheme:
A kind of bactericidal composition is made up of pyraclostrobin and Fluoxastrobin, and the mass ratio of said pyraclostrobin and Fluoxastrobin is 1:0.5-5, is preferably 1:1-5, and more preferably 1:1-3 most preferably is 1:2.
Fluoxastrobin belongs to methoxy acrylic bactericide; Efficiently, wide spectrum, nearly all mycota (Ascomycotina, Basidiomycotina, Mastigomycotina and Deuteromycotina) disease such as powdery mildew, rust, glume blight, net blotch, downy mildew, rice blast etc. are all had good activity.Can be used for cauline leaf spraying, seed treatment, also can carry out soil treatment, be mainly used in cereal, paddy rice, peanut, grape, potato, fruit tree, vegetables, coffee, lawn etc.Its mechanism of action: through the electronics transmission between inhibition cytochrome b and c, thereby suppress mitochondrial breathing, cause germ spore-germination and mycelial growth to be obstructed, finally cause cell death.
Pyraclostrobin (having another name called pyraclostrobin); English name Pyraclostrobin is the New-type wide-spectrum bactericide, has protection, treatment and radical cure effect; It can prevent and treat the plant disease that the fungal pathogens by nearly all types such as ascus guiding principle, Basidiomycetes, Oomycetes causes; Especially diseases such as the powdery mildews of melon, vegetables, downy mildew, scab, leaf spot, eqpidemic disease are had stronger control efficiency, effect rapidly, the lasting period is long.It is again a kind of steroids bactericide simultaneously, can make crop absorb more nitrogen, promotes the growth of crop.This kind not only toxicity is low, to non-target organism safety, and also all friendly safely to user and environment.
Different fungicidal activity components mix each active component of back because the difference of composition, structure, physicochemical property makes that the synergy between each active component is typically expressed as synergistic effect, summation action or antagonism.So-called synergistic effect is exactly the mutual synergism between different material, and the effect of its generation is greater than the sum total of each composition effect; And being exactly the effect of its generation, summation action equals the sum total of each composition effect; Antagonism is meant that a kind of material disturbed the effect of another kind of material when two kinds of materials acted on living organism, or the effect of interfering with an opponent each other, the phenomenon that general effect is descended.
The present invention calculates co-toxicity coefficient evaluation pyraclostrobin and Fluoxastrobin and uses effect with according to Sun Yunpei (Sun Y-P) method, and the result shows co-toxicity coefficient all greater than 120, shows that the mixing use of the two has the notable synergistic effect.
In addition; Respectively all types of bactericide according to the invention and commercially available 250g/L pyraclostrobin EC, 250g/L Fluoxastrobin SC are carried out multiple diseases control test; And the active component consumption is consistent in all bactericide, and the result shows, the preventive effect of the bactericide according to the invention obviously preventive effect than the bactericide of single-activity component is high; Show that each active component does not have cross tolerance in the bactericide according to the invention, control efficiency has synergistic effect.
The present invention also provides a kind of bactericide to be made up of acceptable auxiliary material on bactericidal composition according to the invention and the pesticidal preparations, and the percentage by weight that said bactericidal composition accounts for said bactericide is 1-90%.Bactericidal composition according to the invention can be made into multiple formulation, and like water dispersible granules, suspension emulsion, wetting powder, suspending agent etc., those skilled in the art can adopt conventional auxiliary material that bactericidal composition according to the invention is processed corresponding formulation.
Wherein, When formulation is suspension emulsion; The percentage by weight that said bactericidal composition accounts for suspension emulsion is preferably 10-70%; 25-60% more preferably, other suspension emulsion auxiliary materials get final product according to conventional selection the in this area, are that wetting agent 1%-10%, dispersant 1%-10%, emulsifier 3%-10%, thickener 0.1%-2%, water complement to 100% as preferred suspension emulsion auxiliary material component of the present invention.Wherein wetting agent is preferably one or more in the mixture of lauryl sodium sulfate, dodecyl sodium sulfate, Negel, fatty alcohol polyglycol ether sulphate, fat alcohol polyethylene ether, NPE, sorbitan fatty acid ester APEO, Fluhyzon formaldehyde condensation products, alkylnaphthalene sulfonate and anionic wetting agent; Dispersant is preferably one or more in NNO, sodium lignin sulfonate, calcium lignosulfonate, Sodium Polyacrylate, di-2-ethylhexylphosphine oxide naphthalene sulfonate, alkyl amine group taurate, sodium methylene bis-naphthalene sulfonate formaldehyde condensation products, polyoxyethylene polyoxypropylene block copolymer, carboxymethyl cellulose, sodium phosphate trimer, the alkylnaphthalene sulfonate condensation polymer; Emulsifier is preferably one or more in farming breast 500, farming breast 600, Nongru-700, NP series, 0201B, 0203B, 2201, castor oil polyoxyethylene ether, aliphatic acid polyethenoxy ether, polyoxyethylene aliphatic alcohol ether, ethoxy castor oil, PMA, fatty acid polyethylene glycol ester, the trilaurin APEO.
When formulation is suspending agent; The percentage by weight that said bactericidal composition accounts for suspending agent is preferably 10-40%; 20-30% more preferably; Other suspending agent auxiliary materials get final product according to conventional selection the in this area, are that wetting agent 1%-10%, dispersant 1%-10%, thickener 0.1%-2%, water complement to 100% as preferred suspending agent auxiliary material component of the present invention.Wherein, wetting agent is preferably one or more in the mixture of lauryl sodium sulfate, dodecyl sodium sulfate, Negel, fatty alcohol polyglycol ether sulphate, fat alcohol polyethylene ether, NPE, sorbitan fatty acid ester APEO, Fluhyzon formaldehyde condensation products, alkylnaphthalene sulfonate and anionic wetting agent; Dispersant is preferably one or more in NNO, sodium lignin sulfonate, calcium lignosulfonate, Sodium Polyacrylate, di-2-ethylhexylphosphine oxide naphthalene sulfonate, alkyl amine group taurate, sodium methylene bis-naphthalene sulfonate formaldehyde condensation products, polyoxyethylene polyoxypropylene block copolymer, carboxymethyl cellulose, sodium phosphate trimer, the alkylnaphthalene sulfonate condensation polymer; Said thickener is preferably one or more in xanthans, polyvinyl alcohol, sodium alginate, starch, the organobentonite.
When formulation is wetting powder; The percentage by weight that said bactericidal composition accounts for wetting powder is preferably 20-60%; 35-40% more preferably; Other wetting powder auxiliary materials get final product according to conventional selection the in this area, are that wetting agent 1%-10%, dispersant 1%-10%, carrier complement to 100% as preferred wetting powder auxiliary material component of the present invention.Wherein, wetting agent is preferably one or more in the mixture of lauryl sodium sulfate, dodecyl sodium sulfate, Negel, fatty alcohol polyglycol ether sulphate, fat alcohol polyethylene ether, NPE, sorbitan fatty acid ester APEO, Fluhyzon formaldehyde condensation products, alkylnaphthalene sulfonate and anionic wetting agent; Dispersant is preferably one or more in NNO, sodium lignin sulfonate, calcium lignosulfonate, Sodium Polyacrylate, di-2-ethylhexylphosphine oxide naphthalene sulfonate, alkyl amine group taurate, sodium methylene bis-naphthalene sulfonate formaldehyde condensation products, polyoxyethylene polyoxypropylene block copolymer, carboxymethyl cellulose, sodium phosphate trimer, the alkylnaphthalene sulfonate condensation polymer; Carrier is preferably one or more among bentonite, urea, sodium carboxymethylcellulose, ammonium sulfate, modified starch, mineral salt, white carbon, silica gel, PEG, the SF-04.
When formulation is water dispersible granules; The percentage by weight that said bactericidal composition accounts for water dispersible granules is preferably 10-90%; 50-55% more preferably; Other water dispersible granules auxiliary materials get final product according to conventional selection the in this area, are that wetting agent 1%-10%, dispersant 1%-10%, disintegrant 0.1%-5%, adhesive 0.1%-5%, carrier complement to 100% as preferred water dispersible granules auxiliary material component of the present invention.Wherein, wetting agent is preferably one or more in the mixture of lauryl sodium sulfate, dodecyl sodium sulfate, Negel, fatty alcohol polyglycol ether sulphate, fat alcohol polyethylene ether, NPE, sorbitan fatty acid ester APEO, Fluhyzon formaldehyde condensation products, alkylnaphthalene sulfonate and anionic wetting agent; Dispersant is preferably one or more in NNO, sodium lignin sulfonate, calcium lignosulfonate, Sodium Polyacrylate, di-2-ethylhexylphosphine oxide naphthalene sulfonate, alkyl amine group taurate, sodium methylene bis-naphthalene sulfonate formaldehyde condensation products, polyoxyethylene polyoxypropylene block copolymer, carboxymethyl cellulose, sodium phosphate trimer, the alkylnaphthalene sulfonate condensation polymer; Carrier is preferably one or more among bentonite, urea, sodium carboxymethylcellulose, ammonium sulfate, modified starch, mineral salt, white carbon, silica gel, PEG, the SF-04; Disintegrant is preferably one or more among bentonite, urea, sodium carboxymethylcellulose, ammonium sulfate, modified starch, mineral salt, white carbon, silica gel, PEG, the SF-04; Adhesive is preferably one or more among sucrose, soluble starch, Sodium Polyacrylate, dextrin, xanthans, CMC, the SF-04.
Can know by above technical scheme; Bactericidal composition according to the invention and preparation thereof with pyraclostrobin and azoxystrobin compound as active ingredient, the two mutual supplement with each other's advantages, synergy; Delay the drug-fast generation of fungi; And reduce pollution to environment, and simultaneously the control corps diseases being had synergistic effect, can be widely used in the control of corps diseases.
Embodiment
The embodiment of the invention discloses a kind of bactericidal composition and preparation thereof.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Product of the present invention is described through preferred embodiment, and the related personnel obviously can change or suitably change and combination product as herein described in not breaking away from content of the present invention, spirit and scope, realizes and use technology of the present invention.
Embodiment 1:20% pyraclostrobin Fluoxastrobin suspending agent
Pyraclostrobin 5%, Fluoxastrobin 15%, fat alcohol polyethylene ether 7%, sodium lignin sulfonate 5%, xanthans 1.5%, water supply 100%, through abundant mixed grinding, promptly obtain 20% pyraclostrobin Fluoxastrobin suspending agent.
Embodiment 2:30% pyraclostrobin Fluoxastrobin suspending agent
Pyraclostrobin 10%, Fluoxastrobin 20%, dodecyl sodium sulfate 6%, NNO5%, xanthans 1%, water complement to 100%, through abundant mixed grinding, promptly obtain 30% pyraclostrobin Fluoxastrobin suspending agent.
Embodiment 3:25% pyraclostrobin Fluoxastrobin suspension emulsion
Pyraclostrobin 10%, Fluoxastrobin 15%, dodecyl sodium sulfate 5%, sodium lignin sulfonate 6%, farming breast 6005%, xanthans 0.5%, water complement to 100%, through mixing, grinding, modulation, promptly obtain 25% pyraclostrobin Fluoxastrobin suspension emulsion.
Embodiment 4:60% pyraclostrobin Fluoxastrobin suspension emulsion
Pyraclostrobin 10%, Fluoxastrobin 50%, NPE 7%, NNO5%, 0201B3%, sodium alginate 0.4%, water complement to 100%, through through mixing, grind, modulating, promptly obtain 60% pyraclostrobin Fluoxastrobin suspension emulsion.
Embodiment 5:35% pyraclostrobin Fluoxastrobin wetting powder
Pyraclostrobin 15%, Fluoxastrobin 20%, dodecyl sodium sulfate 4%, carboxymethyl cellulose 5%, kaolin complement to 100%, through fully mixing, comminution by gas stream, mixing, promptly obtain 35% pyraclostrobin Fluoxastrobin wetting powder.
Embodiment 6:40% pyraclostrobin Fluoxastrobin wetting powder
Pyraclostrobin 20%, Fluoxastrobin 20%, lauryl sodium sulfate 7%, alkyl amine group taurate 3%, kaolin complement to 100%, through fully mixing, comminution by gas stream, mixing, promptly obtain 40% pyraclostrobin Fluoxastrobin wetting powder.
Embodiment 7:50% pyraclostrobin azoxystrobin water dispersible granule
Pyraclostrobin 10%, Fluoxastrobin 40%, Negel 6%, sodium lignin sulfonate 5%, urea 2%, xanthans 1%, kaolin supply 100%; Through fully mixing, comminution by gas stream, kneading, granulation, drying and screening, promptly obtain 50% pyraclostrobin azoxystrobin water dispersible granule.
Embodiment 8:55% pyraclostrobin azoxystrobin water dispersible granule
Pyraclostrobin 15%, Fluoxastrobin 40%, NPE 5%, carboxymethyl cellulose 8%, ammonium sulfate 1%, xanthans 2%, kaolin supply 100%; Through fully mixing, comminution by gas stream, kneading, granulation, drying and screening, promptly obtain 55% pyraclostrobin azoxystrobin water dispersible granule.
Embodiment 9: the test of pesticide effectiveness
For being tried agricultural chemicals, application dosage is 200g (a.i.)/hm in active component with the pyraclostrobin Fluoxastrobin medicament of embodiment 1-8 preparation, commercially available 250g/L pyraclostrobin EC, commercially available 250g/L Fluoxastrobin SC
2, prevent and treat the result and see table 1.
Table 1 test of pesticide effectiveness (%)
Can be known that by table 1 two kinds of components of bactericidal composition according to the invention do not have cross tolerance, composite back drug effect has synergistic effect apparently higher than the drug effect of commercially available 250g/L pyraclostrobin EC and commercially available 250g/L Fluoxastrobin SC single-activity composition.
The explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof.Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of claim of the present invention.
Claims (10)
1. a bactericidal composition is characterized in that, is made up of pyraclostrobin and Fluoxastrobin, and the mass ratio of said pyraclostrobin and Fluoxastrobin is 1:0.5-5.
2. according to the said bactericidal composition of claim 1, it is characterized in that the mass ratio of said pyraclostrobin and Fluoxastrobin is 1:1-3.
3. according to the said bactericidal composition of claim 2, it is characterized in that the mass ratio of said pyraclostrobin and Fluoxastrobin is 1:2.
4. a bactericide is characterized in that, is made up of acceptable auxiliary material on said bactericidal composition of claim 1 and the pesticidal preparations, and the percentage by weight that said bactericidal composition accounts for said bactericide is 1-90%.
5. according to the said bactericide of claim 4, it is characterized in that it is suspension emulsion, suspending agent, wetting powder or water dispersible granules.
6. according to the said bactericide of claim 5, it is characterized in that it is a suspension emulsion, the percentage by weight that wherein said bactericidal composition accounts for suspension emulsion is 10-70%.
7. according to the said bactericide of claim 5, it is characterized in that it is a suspending agent, the percentage by weight that wherein said bactericidal composition accounts for suspending agent is 10-40%.
8. according to the said bactericide of claim 5, it is characterized in that it is a wetting powder, the percentage by weight that wherein said bactericidal composition accounts for wetting powder is 20-60%.
9. according to the said bactericide of claim 5, it is characterized in that it is a water dispersible granules, the percentage by weight that wherein said bactericidal composition accounts for water dispersible granules is 10-90%.
10. the application of any said bactericide of claim 4-9 in the control corps diseases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210301984.8A CN102805091B (en) | 2012-08-22 | 2012-08-22 | Bactericidal composition and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210301984.8A CN102805091B (en) | 2012-08-22 | 2012-08-22 | Bactericidal composition and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102805091A true CN102805091A (en) | 2012-12-05 |
| CN102805091B CN102805091B (en) | 2014-01-15 |
Family
ID=47229099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210301984.8A Expired - Fee Related CN102805091B (en) | 2012-08-22 | 2012-08-22 | Bactericidal composition and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102805091B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105994323A (en) * | 2016-05-28 | 2016-10-12 | 安徽广信农化股份有限公司 | Bactericidal composition containing azoxystrobin and pyrazole azoxystrobin |
| CN108651497A (en) * | 2018-06-21 | 2018-10-16 | 浙江新农化工股份有限公司 | Pyraclostrobin-containing and alkene oxime amine bactericidal composition and application thereof and agriculture chemicals fungicide |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101969776A (en) * | 2007-11-29 | 2011-02-09 | 拜尔农作物科学股份公司 | Method for reducing mycotoxin contamination in maize |
-
2012
- 2012-08-22 CN CN201210301984.8A patent/CN102805091B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101969776A (en) * | 2007-11-29 | 2011-02-09 | 拜尔农作物科学股份公司 | Method for reducing mycotoxin contamination in maize |
Non-Patent Citations (1)
| Title |
|---|
| 洪文英等: "《嘧菌酯和吡唑醚菌酯在黄瓜中的残留降解行为及安全使用》", 《浙江农业学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105994323A (en) * | 2016-05-28 | 2016-10-12 | 安徽广信农化股份有限公司 | Bactericidal composition containing azoxystrobin and pyrazole azoxystrobin |
| CN108651497A (en) * | 2018-06-21 | 2018-10-16 | 浙江新农化工股份有限公司 | Pyraclostrobin-containing and alkene oxime amine bactericidal composition and application thereof and agriculture chemicals fungicide |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102805091B (en) | 2014-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101836633A (en) | Pesticide composition containing amino-oligosaccharide and kresoxim-methyl and use method and application thereof | |
| CN101647441B (en) | Sterilization combination containing azoxystrobin and application thereof | |
| CN105191946A (en) | Sterilization composition and application thereof | |
| CN101946775A (en) | Sterilization compound containing triazole fungicide and azoxystrobin | |
| CN101647454A (en) | Sterilizing composition containing cyprodinil | |
| CN102239853A (en) | Thifluzamide-containing composite bacteriacide | |
| CN101755784B (en) | Oomycete killing composition | |
| CN102150659A (en) | Bactericide composition, preparation and application thereof | |
| CN101653131B (en) | Bactericidal composition containing azoxystrobin | |
| CN101584329B (en) | 2-cyano-3-amino-3-phenylancryic acetate and propineb-containing synergistic antiseptic composition | |
| CN101263821B (en) | Sterilizing composition | |
| CN102578102A (en) | Sterilizing composition and preparation thereof | |
| CN102805091B (en) | Bactericidal composition and preparation thereof | |
| CN100364400C (en) | Germicide composition containing pyraclostrobin and chlorothalonil and its application | |
| CN103385244A (en) | Bactericidal composition comprising fluxapyroxad and thiocarbamate | |
| CN101755759A (en) | Fungicidal composition containing dithianon and azoxystrobin | |
| CN102578103A (en) | Sterilizing composition and preparation thereof | |
| CN103109815B (en) | Dimoxystrobin and azoxystrobin pesticide composition | |
| CN102599172A (en) | Insecticidal composition and preparation thereof | |
| CN101703058A (en) | germicide composite containing azoxystrobin and propineb | |
| CN102578104A (en) | Sterilizing composition and preparation thereof | |
| CN101731246B (en) | Cyprodinil and propineb-containing sterilizing composition | |
| CN106719750A (en) | A kind of bactericidal composition of pyraclostrobin-containing and Physcion | |
| CN102578105A (en) | Bactericidal composition and preparation thereof | |
| CN104186525A (en) | Bactericidal composition containing methylene dithiocyanate and strobilurin components |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140115 |