CN102793882B - Traditional Chinese medicine for treatment of myasthenia gravis - Google Patents
Traditional Chinese medicine for treatment of myasthenia gravis Download PDFInfo
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- CN102793882B CN102793882B CN 201210304722 CN201210304722A CN102793882B CN 102793882 B CN102793882 B CN 102793882B CN 201210304722 CN201210304722 CN 201210304722 CN 201210304722 A CN201210304722 A CN 201210304722A CN 102793882 B CN102793882 B CN 102793882B
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Abstract
The invention relates to a traditional Chinese medicine for treatment of myasthenia gravis, and is characterized by being prepared by the following raw medicinal materials by weight: 1 part of storax, 12 parts of white atractylodes rhizome, 6 parts of rhodiola rosea, 8 parts of exocarpium citri rubrum, 9 parts of alpinia oxyphylla, 12 parts of prepared rehmannia root, 8 parts of dodder, and 20 parts of coriolus versicolor. Clinical studies prove that the traditional Chinese medicine can safely and effectively treat myasthenia gravis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of myasthenia gravis.
Background technology
Myasthenia gravis is a kind of common mood disorders, can be caused by a variety of causes, and low with remarkable and persistent mental state is main clinical characteristics, and mental state is low unbecoming with its situation, and suicidal thought and behavior can appear in severe patient.Present medicine is cured the symptoms, not the disease, and commonly used dependency and side effect is arranged.Therefore the Chinese medicine of researching and developing a kind of safe and effective treatment myasthenia gravis is very with practical value.
The present Research of medical material involved in the present invention is as follows:
Styrax: this product is that the balsam that the trunk of Hamamelidaceae plant Styrax tree LiquidambarorientalisMill. oozes out forms through processing and refining.[nature and flavor with return through] suffering, temperature.GUIXIN, spleen channel.[function with cure mainly] has one's ideas straightened out, ward off dirty, pain relieving.Be used for the apoplexy syncope due to accumulation of phlegm, suddenly faint, obstruction of qi in the chest and cardialgia, breast abdomen cold type of pain, infantile convulsion.[usage and consumption] 0.3～1g, pleasant ball loose and obey.
The Rhizoma Atractylodis Macrocephalae: this product is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae AtractylodesmacrocephalaKoidz..[nature and flavor with return through] are bitter, sweet, temperature.Return spleen, stomach warp.[function with cure mainly] invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.[usage and consumption] 6～12g.
Radix Rhodiolae: this product is dry root and the rhizome of Crassulaceae plant Radix Rhodiolae Rhodiolacrenulata (Hook.f.etThoms.) H.Ohba.[nature and flavor with return through] are sweet, bitter, and are flat.Return lung, heart channel.[function with cure mainly] benefiting QI for activating blood circulation is promoted blood circulation and is relievingd asthma.Be used for blood stasis due to qi deficiency, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, asthenia asthma.[usage and consumption] 3～6g.
Tangerine: this product is the dry outer peel of rutaceae orange CitrusreticulataBlanco and variety thereof.[nature and flavor with return through] are hot, bitter, temperature.Return lung, spleen channel.[function with cure mainly] regulating the flow of QI to ease the stomach, drying dampness to eliminate phlegm.Be used for cough with copious phlegm, food stagnation is got sick from drinking too much wine, and the vomiting and nausea painful abdominal mass is vexed.[usage and consumption] 3～10g.
Fructus Alpiniae Oxyphyllae: this product is the dry mature fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae AlpiniaoxyphyllaMiq..[nature and flavor with return through] suffering, temperature.Return spleen, kidney channel.[function with cure mainly] warming the kidney controlling nocturnal emission with astringent drugs reducing urination is warming spleen and stopping diarrhaly taken the photograph saliva.Be used for enuresis due to deficiency of the kidney, frequent micturition, the seminal emission nebulousurine, spleen-cold syndrome is had loose bowels, cold type of pain in the abdomen, mouthful many salivas.[usage and consumption] 3～10g.
Radix Rehmanniae Preparata: this product is the process of preparing Chinese medicine processed goods of Radix Rehmanniae.[nature and flavor with return through] are sweet, tepor.Return liver, kidney channel.[function with the cure mainly] YIN nourishing of enriching blood, beneficial essence is filled out marrow.Be used for blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, and is dizzy, tinnitus, early whitening of beard and hair.[usage and consumption] 9～15g.
Semen Cuscutae: this product is the dry mature seed of convolvulaceous plant south Semen Cuscutae CuscutaaustralisR.Br. or Semen Cuscutae CuscutachinensisLam..[nature and flavor with return through] are hot, sweet, and are flat.Return the liver,kidney,spleen warp.[function with cure mainly] liver and kidney tonifying, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal; External pathogenic wind expelling speckle dispelling.Be used for deficiency of the liver and kindey, soreness of the waist and knees, impotence and seminal emission, enuresis frequent micturition.Vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, blurred vision tinnitus, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.[usage and consumption] 6～12g.
Coriolous Dersicolor (Fr.) Quel: this product is the dry sporophore of Polyporaceae fungus Corilus versicolor Quel. coriolusversiolor (LexFr.) Quel.[nature and flavor with return through] are sweet, and are flat.GUIXIN, spleen, liver, kidney channel.[function with cure mainly] invigorating spleen to remove dampness, heat-clearing and toxic substances removing.Be used for jaundice due to damp-heat, hypochondriac pain, poor appetite, fatigue and weakness.[usage and consumption] 9～27g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of myasthenia gravis, by selecting suitable medical material and proportioning thereof, reaches the purpose of safe and effective healing myasthenia gravis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of myasthenia gravis is characterized in that, it is to be prepared from by following bulk drugs material: 1 part of Styrax, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Rhodiolaes, 8 parts of dried tangerine peels, 9 parts of Fructus Alpiniae Oxyphyllaes, 12 parts of Radix Rehmanniae Preparata, 8 parts of Semen Cuscutae, 20 parts of Coriolous Dersicolor (Fr.) Quel.
Below in conjunction with Chinese medicine mechanism beneficial effect of the present invention is described:
The inventor thinks, myasthenia gravis is mainly because weakness of the spleen and stomach, deficiency of the liver and kindey causes, should be the treatment standard with the spleen strengthening and damp drying, liver and kidney tonifying during treatment.The present invention utilization: Styrax have one's ideas straightened out ward off dirty; The Rhizoma Atractylodis Macrocephalae, Coriolous Dersicolor (Fr.) Quel the spleen strengthening and damp drying; The Radix Rehmanniae Preparata YIN nourishing of enriching blood, beneficial essence is filled out marrow; Fructus Alpiniae Oxyphyllae warming the kidney controlling nocturnal emission with astringent drugs; The Semen Cuscutae liver and kidney tonifying; The Radix Rhodiolae supplementing qi and invigorating vasculum; Tangerine regulating the flow of QI to ease the stomach; All medicines share, and play the effect of the spleen strengthening and damp drying, liver and kidney tonifying altogether, from basic treatment conditioning myasthenia gravis.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The out-patient that the inventor collects 75 routine myasthenia graviss between year April in June, 2011-2012 altogether, wherein male 32 examples, women 43 examples.Be divided at random: 50 examples are organized in treatment, matched group 25 examples.Data such as two groups of sexes, age, the state of an illness there are no significant difference has comparability.
2, test method
The oral pyridostigmine bromide sheet of matched group uses to specifications.1 month course of treatment.
The capsule that oral the present invention makes according to specific embodiment 1 is organized in treatment, divides every day and takes for 2 times.1 month course of treatment.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and recurrence was not seen in drug withdrawal in two months.Take a turn for the better: clinical symptom relief.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
3.2 treatment statistical result sees Table 1.
Table 1 liang group curative effect relatively
| Group | n | Recovery from illness | Take a turn for the better | Invalid | The untoward reaction example | Total effective rate (%) |
| The treatment group | 50 | 12（24%） | 36 | 2 | 0（0%） | 96% |
| Matched group | 25 | 0（0%） | 17 | 8 | 2（8%） | 68% |
As seen, the medicine that makes of the preferred embodiment for the present invention can safe and effective treatment myasthenia gravis.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing Rhizoma Atractylodis Macrocephalae 12g, Radix Rhodiolae 6g, tangerine 8g, Fructus Alpiniae Oxyphyllae 9g, Radix Rehmanniae Preparata 12g, Semen Cuscutae 8g, Coriolous Dersicolor (Fr.) Quel 20g; Add 8 times of water gagings, decocted 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate concentrates, and is dried to powder, adds Storax 1g, and mixing incapsulates shell, promptly gets the capsule that meets one day consumption of normal adult.
Be used for the treatment of myasthenia gravis.Oral, divide sooner or later every day and take for twice.
Claims (1)
1. a Chinese medicine for the treatment of myasthenia gravis is characterized in that, it is to be prepared from by following bulk drugs material: 20 parts of 1 part of Styrax, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Rhodiolaes, tangerine 8 parts, 9 parts of Fructus Alpiniae Oxyphyllaes, 12 parts of Radix Rehmanniae Preparata, 8 parts of Semen Cuscutae and Coriolous Dersicolor (Fr.) Quel.
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| CN 201210304722 CN102793882B (en) | 2012-08-25 | 2012-08-25 | Traditional Chinese medicine for treatment of myasthenia gravis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1183980A (en) * | 1997-08-02 | 1998-06-10 | 迟经惠 | Decoction for serious amyasthenia |
| CN100400090C (en) * | 2005-07-29 | 2008-07-09 | 卜绿萍 | Medicine composition for treating myasthenia gravis and prepn. method therefor |
| CN101077413A (en) * | 2006-05-26 | 2007-11-28 | 张晋玮 | Neuropeptide compound preparation for detoxification and addiction-removing |
| CN101537115A (en) * | 2008-03-19 | 2009-09-23 | 北京汉潮联创中药科技有限公司 | Chinese medicinal preparation for treating myasthenia gravis |
| CN101352514A (en) * | 2008-05-04 | 2009-01-28 | 北京中科仁和科技有限公司 | Chinese medicinal composition for treating myasthenia gravis and preparation method thereof |
| CN101732461B (en) * | 2008-11-11 | 2013-07-31 | 禅武医基金会有限公司 | Composition for improving brain function and/or treating encephalopathy |
| CN101554451A (en) * | 2009-05-14 | 2009-10-14 | 宋水清 | Ginseng and antler muscle strengthening pills and preparation method thereof |
| CN102018818A (en) * | 2009-09-11 | 2011-04-20 | 冒文敏 | Medicine for treating myasthenia gravis |
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