CN102783487B - A kind of cyazofamid aqueous suspension agent and preparation method thereof - Google Patents
A kind of cyazofamid aqueous suspension agent and preparation method thereof Download PDFInfo
- Publication number
- CN102783487B CN102783487B CN201210238769.8A CN201210238769A CN102783487B CN 102783487 B CN102783487 B CN 102783487B CN 201210238769 A CN201210238769 A CN 201210238769A CN 102783487 B CN102783487 B CN 102783487B
- Authority
- CN
- China
- Prior art keywords
- agent
- cyazofamid
- aqueous suspension
- suspension agent
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses aqueous suspension agent of a kind of cyazofamid and preparation method thereof, in cyazofamid aqueous suspension agent, the percentage by weight of each component is: cyazofamid 1 ~ 50%; Dispersant 1 ~ 8%; Wetting agent 1 ~ 10%; Thickening stabilizing agent 0.1 ~ 2%; Antifreezing agent 1 ~ 10%; Defoamer 0.1 ~ 1%; Preservative 0.1 ~ 0.5%; PH adjusting agent regulates pH to be 6 ~ 8; Surplus is deionized water.Except thickening stabilizing agent, by above-mentioned material stirring, sand milling, add thickening stabilizing agent more afterwards, stir, and add appropriate pH adjusting agent.It is high that the present invention has flash-point, nonflammable non-explosive, the advantage such as production, storage, use safety, environmental pollution is little, product cost is low, easy packaging.
Description
Technical field
The present invention relates to a kind of pesticidal preparations and preparation method thereof, specifically a kind of aqueous suspension agent and preparation method thereof of cyazofamid.
Background technology
Chemical control is the important means that the mankind prevent and treat agricultural damage by disease and insect, chemical pesticide is to ensureing that the increasing both production and income of agricultural plays very important effect, but the use of agricultural chemicals, while Ensuring Food Safety is produced, also bring a series of environment and the social concerns such as residual, pollution.Therefore, the developing direction of pesticidal preparations industry is progressively to safe, environmental protection, water baseization development.Agricultural chemicals suspension agent refers to the preparation be scattered in the particulate homogenous of less than 4 microns by former for solid pesticide medicine in water, and be a kind of nonflammable explosive, particle diameter is little, and biologically active is high, and proportion is comparatively large, the environmental protection type agricultural chemical formulation that packaging volume is less.
Pesticide suspension concentrate has the following advantages compared with conventional dosage forms: without dust harzard; Take water as dispersion medium, the inflammable and drug injury problem do not produced by organic solvent; Than great, packaging volume is little; The dispersiveness of suspending agent and plate-out ability are all relatively good, and suspensibility is high, and the ability sticking to plant corpus surface is stronger, resistance of rainwater washing against, and thus comparatively wetting powder is significantly and also more lasting for drug effect; Have that particle is little, active surface is large, penetration is strong, cost is low, drug effect is high.Therefore, aqueous suspension agent is other formulations of pesticide safety and environmental protections relatively, have become the pesticide species that water baseization pesticides new formulation tonnage is larger.
Cyazofamid is sulphaguanidine azoles fungicide, protective fungicide, and to downy mildew, epidemic disease, club root, damping off etc. have special efficacy.Mechanism of action is the supply that the electron transmission blocking Oomycete germ body mitochondrial cytochrome b c1 complex carrys out interfering energy, and its binding site is Mei Q1 center, with other bactericide without cross tolerance.Its height to pathogen selects activity may be because the sensitivity difference of target enzymes to medicament causes.To the plasmodiophora brassica bacteria of Oomycete fungal as downy mildew, Pseudo peronospara, phytophthora, pythium spp and Plasmodiophoromycetes, there is very high biologically active.The preparation of cyazofamid single dose is had to have pulvis, wetting powder, water dispersible granules in the market.And wetting powder, pulvis also exist big for environment pollution, there is the shortcomings such as power consumption of polymer processing is high in water dispersible granules, and relevant cyazofamid aqueous suspension agent also appears in the newspapers at end.The present invention, aiming to provide environmentally-friendly water-based agent type of a kind of cyazofamid and preparation method thereof, overcomes the shortcoming of existing formulation.
Summary of the invention
The object of the invention is to provide for big for environment pollution, the shortcoming such as preparation processing energy consumption is high existing for the existing formulation of cyazofamid a kind of, cyazofamid aqueous suspension agent that power consumption of polymer processing low little to environment shadow.
Another object of the present invention is the preparation method providing a kind of cyazofamid aqueous suspension agent, for pesticide industry provides a kind of novel form and new product, serves agricultural production.
Technical scheme of the present invention: for achieving the above object, the invention provides a kind of cyazofamid aqueous suspension agent, each component is as follows by weight percentage: cyazofamid: 1 ~ 50%; Dispersant: 1 ~ 8%; Wetting agent: 1 ~ 10%; Thickening stabilizing agent: 0.1 ~ 2%; Antifreezing agent: 1 ~ 10%; Defoamer: 0.1 ~ 1%; Preservative: 0.1 ~ 0.5%; PH adjusting agent regulates pH to be 6 ~ 8, and surplus is deionized water.
Wherein: described dispersant selects sodium lignin sulfonate, lignin calcium iodate, polycarboxylic acid salt, lauryl alcohol polyethylene glycol oxide base ether sodium sulfate, alkyl naphthalene formaldehyde condensate sulfonates, lauryl sodium sulfate, oleic acid salt, the mixing of one or more in alkyl polyoxyethylene ether sulfonate, alkylphenol-polyethenoxy base ether formaldehyde condensation products, polyoxyethylene polyoxypropylene base ether block copolymers, alkylpolyoxyethylene phosphate or alkyl naphthalene formaldehyde condensate sulfonates.
Described wetting agent is selected neopelex, is pulled open powder, the mixing of one or more in alkyl phenol formaldehyde resin polyoxyethylene ether sulphate, alkylphenol-polyethenoxy base ether, Nonyl pheno base ether, detergent, emulsifier 2000 series, wetting and penetrating agent T.
Described thickening stabilizing agent selects the mixing of one or more in water-soluble resin, xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, hydrated SiO 2, bentonite, polyvinyl alcohol, polyvinyl alcohol.
The one in ethylene glycol, propane diols, glycerine, urea selected by described antifreezing agent.
Described defoamer selects silicone oil, organic silicone, C
10-C
20saturated fat acid compounds, C
8-C
10aliphatic alcohols compound in the mixing of one or more.
The one in potassium sorbate, sodium sorbate, Sodium Benzoate, Kathon CG KF88 selected by described preservative.
Adding appropriate pH adjusting agent adjust ph in described cyazofamid aqueous suspension agent is 6 ~ 8.The mixing of one or more in sodium hydroxide, ammoniacal liquor, acetic acid, citric acid or phosphoric acid selected by PH conditioning agent.
Cyazofamid aqueous suspension agent preparation method of the present invention: even by carrying out shear-mixed in former for load weighted cyazofamid medicine, dispersant, wetting agent, antifreezing agent, defoamer, preservative and deionized water input stirred tank, then pass into sand mill and carry out sand milling 4 ~ 6 times, after sand milling to particle diameter≤5um, add thickening stabilizing agent, shear agitation is even again, adding appropriate pH adjusting agent adjust ph is 6 ~ 8, i.e. obtained cyazofamid aqueous suspension agent.
In recent years, due to the enhancing of people's environmental consciousness, make suspending agent gradually by the trend that will replace the non-green pesticide form such as missible oil, pulvis in the past, agricultural chemicals new component newly developed in recent years goes on the market mainly with suspending agent greatly.And its particle diameter is little, suspensibility is high, and have at crop leaf the adhesivity that height opens up, in drug effect, comparatively conventional dosage forms improves a lot.
The present invention by cyazofamid with the Granular composite of miniaturization in water, be prepared into aqueous suspension agent, have the following advantages.
1, product cost is low, easily packs.
2, take water as matrix, without dust, environmental pollution is little, to production and user's safety.
3, water baseization product, flash-point is high, does not fire not quick-fried, produces storage safety.
4, after said preparation spraying, be distributed in blade surface with fine particle, make it infiltrate blade face fast, improve bactericidal effect.
Embodiment
The present invention is described by following specific embodiment, but the invention is not restricted to following specific embodiment.In these embodiments, unless otherwise indicated, all percentage is all weight percentage.
Embodiment 1.
According to technical scheme of the present invention, take the former medicine 5% of cyazofamid, dispersant lignin calcium iodate 2%, wetting agent alkylphenol-polyethenoxy base ether 2%, antifreeze glycol 5%, defoamer organic silicone 0.4%, preservative Kathon CG KF88 0.1%, add deionized water to 100%, mix rear sand milling to qualified particle diameter, add thickening stabilizing agent xanthans 0.2%, shear agitation is even, sodium hydroxide is used to regulate pH to be 6 ~ 8, i.e. obtained 5% cyazofamid aqueous suspension agent.
Embodiment 2.
According to technical scheme of the present invention, take the former medicine 10% of cyazofamid, dispersant polycarboxylate 3%, wetting agent SOPA1.5%, antifreeze glycol 5%, defoamer organic silicone 0.4%, potassium sorbate preservative 0.2%, add deionized water to 100%, mix rear sand milling to qualified particle diameter, add thickening stabilizing agent Magnesiumaluminumsilicate 1%, shear agitation is even, ammoniacal liquor is used to regulate pH to be 6 ~ 8, i.e. obtained 10% cyazofamid aqueous suspension agent.
Embodiment 3.
According to technical scheme of the present invention, take the former medicine 50% of cyazofamid, dispersant polyoxyethylene polyoxypropylene base ether block copolymers 4%, wetting agent pulls open powder 1%, antifreeze glycol 5%, defoamer organic silicone 0.4%, preservative Kathon CG KF88 0.1%, add deionized water to 100%, mix rear sand milling to qualified particle diameter, add thickening stabilizing agent polyvinyl alcohol 0.15%, shear agitation is even, sodium hydroxide is used to regulate pH to be 6 ~ 8, i.e. obtained 50% cyazofamid aqueous suspension agent.
Embodiment 4.
5% cyazofamid aqueous suspension agent of the embodiment of the present invention 1 ~ 3,10% cyazofamid aqueous suspension agent, 50% cyazofamid aqueous suspension agent are as follows to cucumber damping off control efficiency:
。
As can be seen from control efficiency, cyazofamid aqueous suspension agent of the present invention is when suitably reducing active ingredient dosage, and control efficiency is suitable with cyazofamid water dispersible granules.After cyazofamid aqueous suspension agent spraying use of the present invention, be distributed in crop surface with fine particle, reduction effective ingredient dosage that can be suitable.
Claims (1)
1. a cyazofamid aqueous suspension agent, it is characterized in that: each component is as follows by weight percentage: take the former medicine 50% of cyazofamid, dispersant polyoxyethylene polyoxypropylene base ether block copolymers 4%, wetting agent pulls open powder 1%, antifreeze glycol 5%, defoamer organic silicone 0.4%, preservative Kathon CG KF88 0.1%, add deionized water to 100%, mix rear sand milling to qualified particle diameter, add thickening stabilizing agent polyvinyl alcohol 0.15%, shear agitation is even, sodium hydroxide is used to regulate pH to be 6 ~ 8, i.e. obtained 50% cyazofamid aqueous suspension agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210238769.8A CN102783487B (en) | 2012-07-11 | 2012-07-11 | A kind of cyazofamid aqueous suspension agent and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210238769.8A CN102783487B (en) | 2012-07-11 | 2012-07-11 | A kind of cyazofamid aqueous suspension agent and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102783487A CN102783487A (en) | 2012-11-21 |
| CN102783487B true CN102783487B (en) | 2015-11-18 |
Family
ID=47149252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210238769.8A Active CN102783487B (en) | 2012-07-11 | 2012-07-11 | A kind of cyazofamid aqueous suspension agent and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102783487B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103719100A (en) * | 2013-12-09 | 2014-04-16 | 江阴苏利化学股份有限公司 | Sterilization composite containing cyazofamid and flutriafol |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647451A (en) * | 2009-07-31 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Sterilization combination containing cyazofamid |
| CN101874488A (en) * | 2010-03-13 | 2010-11-03 | 陕西美邦农资贸易有限公司 | Bactericide composition containing imazalil and cyazofamid |
| CN102428918A (en) * | 2011-11-20 | 2012-05-02 | 广东中迅农科股份有限公司 | Fenoxanil aqueous suspension and preparation method thereof |
-
2012
- 2012-07-11 CN CN201210238769.8A patent/CN102783487B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647451A (en) * | 2009-07-31 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Sterilization combination containing cyazofamid |
| CN101874488A (en) * | 2010-03-13 | 2010-11-03 | 陕西美邦农资贸易有限公司 | Bactericide composition containing imazalil and cyazofamid |
| CN102428918A (en) * | 2011-11-20 | 2012-05-02 | 广东中迅农科股份有限公司 | Fenoxanil aqueous suspension and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102783487A (en) | 2012-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102805090A (en) | Pyraclostrobin aqueous suspension agent and preparation method of pyraclostrobin aqueous suspension agent | |
| CN102726403A (en) | Azoxystrobin suspension concentrate and preparation method thereof | |
| CN102258037B (en) | Containing the bactericidal composition of benziothiazolinone and Tebuconazole | |
| CN103283719B (en) | Bifenazate aqueous suspension agent and preparation method thereof | |
| CN101861866B (en) | Pesticide compound containing thifluzamide and hexaconazole and application thereof | |
| CN102428918B (en) | Fenoxanil aqueous suspension and preparation method thereof | |
| CN101690484B (en) | Suspending agent compounded by dimethomorph and cyazofamid as well as preparation method thereof | |
| CN106942240A (en) | A kind of microbicide compositions comprising emodin derivates and BIT | |
| CN102334493B (en) | Novel fluopicolide-containing antibacterial composition | |
| CN102823609A (en) | Purpose of sterilization agent composition for preventing and treating rice diseases | |
| CN102783487B (en) | A kind of cyazofamid aqueous suspension agent and preparation method thereof | |
| CN101946779A (en) | Biologically-chemically synergistic bactericidal suspension and preparation method thereof | |
| CN103210907A (en) | Zoxamide water suspension and preparation method thereof | |
| CN101953345A (en) | Synergistic sterilizing wettable powder and preparation method thereof | |
| CN105165812A (en) | Suspending agent containing styrene-acrylic emulsion and preparation method thereof | |
| CN102696582A (en) | Flonicamid suspension concentrate and method for preparing same | |
| CN105613553A (en) | Anti-hydrolysis nicosulfuron water suspension and preparation method therefor | |
| CN102783480B (en) | A kind of benzene metsulfovax aqueous suspension agent and preparation method thereof | |
| CN101926335A (en) | Sterilizing suspending agent with synergistic effect and preparation method thereof | |
| CN101999366B (en) | Bactericide composition containing ethirimol | |
| CN101692816A (en) | Bactericide suspending agent compounded of dimethomorph and amistar and process for preparing same | |
| CN101485312B (en) | Bactericidal composition containing thiabendazole and epoxiconazole and use thereof | |
| CN103210908A (en) | Chromafenozide suspending agent and preparation method thereof | |
| CN105638670B (en) | A kind of bactericidal composition containing fluorine bacterium azoles and oxazole | |
| CN102204544A (en) | Picoxystrobin-containing synergic bactericidal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20161027 Address after: 610300 Sichuan Province, Chengdu District of Qingbaijiang City Industrial Development Zone Tongji Road No. 903 Patentee after: Chengdu Kelilong Biochemical Co.,Ltd. Address before: 516000 Guangdong province Huizhou Zhongkai hi tech Development Zone No. 24 District Patentee before: Guangdong Zhongxun Agricultural Technology Co., Ltd. |