CN102782124B - 用于产生富含多不饱和脂肪酸的油的新δ9-延伸酶 - Google Patents

用于产生富含多不饱和脂肪酸的油的新δ9-延伸酶 Download PDF

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Publication number
CN102782124B
CN102782124B CN201080041384.1A CN201080041384A CN102782124B CN 102782124 B CN102782124 B CN 102782124B CN 201080041384 A CN201080041384 A CN 201080041384A CN 102782124 B CN102782124 B CN 102782124B
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leu
phe
seq
polyunsaturated fatty
ala
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English (en)
Chinese (zh)
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CN102782124A (zh
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S.佩雷拉
T.达斯
P.克里什南
P.穆克吉
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Abbott Laboratories
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Abbott Laboratories
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Fats And Perfumes (AREA)
  • Edible Oils And Fats (AREA)
CN201080041384.1A 2009-07-17 2010-07-14 用于产生富含多不饱和脂肪酸的油的新δ9-延伸酶 Expired - Fee Related CN102782124B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/505,293 US8188335B2 (en) 2009-07-17 2009-07-17 Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
US12/505293 2009-07-17
PCT/US2010/041893 WO2011008803A2 (en) 2009-07-17 2010-07-14 Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils

Publications (2)

Publication Number Publication Date
CN102782124A CN102782124A (zh) 2012-11-14
CN102782124B true CN102782124B (zh) 2015-04-22

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CN201080041384.1A Expired - Fee Related CN102782124B (zh) 2009-07-17 2010-07-14 用于产生富含多不饱和脂肪酸的油的新δ9-延伸酶

Country Status (15)

Country Link
US (1) US8188335B2 (enExample)
EP (1) EP2454365A2 (enExample)
JP (1) JP2012533303A (enExample)
CN (1) CN102782124B (enExample)
AR (1) AR077763A1 (enExample)
AU (1) AU2010273508B2 (enExample)
BR (1) BR112012001125A2 (enExample)
CA (1) CA2768318A1 (enExample)
IN (1) IN2012DN00469A (enExample)
MX (1) MX2012000825A (enExample)
MY (1) MY160166A (enExample)
NZ (1) NZ597679A (enExample)
RU (1) RU2558302C2 (enExample)
UA (1) UA107468C2 (enExample)
WO (1) WO2011008803A2 (enExample)

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PL1756280T3 (pl) 2004-04-22 2015-04-30 Commw Scient Ind Res Org Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
BRPI0716075A2 (pt) 2006-08-29 2013-08-06 Commw Scient Ind Res Org sÍntese de Ácidos graxos
CA3015426C (en) 2008-11-18 2020-01-14 Commonwealth Scientific And Industrial Research Organisation Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
BR112014013098A2 (pt) * 2011-11-29 2017-06-13 Dignity Sciences Ltd composições compreendendo ácidos graxos que têm 20 carbonos e métodos de produção e uso dos mesmos
HUE033766T2 (en) 2012-06-15 2018-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
EA037817B1 (ru) 2013-12-18 2021-05-25 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
SG11201708106TA (en) * 2015-04-08 2017-10-30 Euglena Co Ltd Suppressive agent for rheumatoid arthritis, prophylactic agent for rheumatoid arthritis, therapeutic agent for rheumatoid arthritis, and food for suppressing rheumatoid arthritis
CN109563517A (zh) 2016-06-01 2019-04-02 加拿大国家研究委员会 菟葵脂肪酸延伸酶及其在脂肪酸生产中的用途
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases

Citations (2)

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US20070117190A1 (en) * 2005-11-23 2007-05-24 Damude Howard G Delta-9 elongases and their use in making polyunsaturated fatty acids
US20080254195A1 (en) * 2007-04-16 2008-10-16 Howard Glenn Damude Delta-9 elongases and their use in making polyunsaturated fatty acids

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Publication number Priority date Publication date Assignee Title
US20070117190A1 (en) * 2005-11-23 2007-05-24 Damude Howard G Delta-9 elongases and their use in making polyunsaturated fatty acids
US20080254195A1 (en) * 2007-04-16 2008-10-16 Howard Glenn Damude Delta-9 elongases and their use in making polyunsaturated fatty acids

Also Published As

Publication number Publication date
CN102782124A (zh) 2012-11-14
WO2011008803A3 (en) 2011-04-07
WO2011008803A2 (en) 2011-01-20
UA107468C2 (uk) 2015-01-12
US8188335B2 (en) 2012-05-29
JP2012533303A (ja) 2012-12-27
AU2010273508A1 (en) 2012-02-09
IN2012DN00469A (enExample) 2015-06-05
MX2012000825A (es) 2012-04-19
US20110016585A1 (en) 2011-01-20
NZ597679A (en) 2013-06-28
RU2012103248A (ru) 2013-08-27
BR112012001125A2 (pt) 2015-09-01
EP2454365A2 (en) 2012-05-23
CA2768318A1 (en) 2011-01-20
AU2010273508B2 (en) 2015-02-05
MY160166A (en) 2017-02-28
AR077763A1 (es) 2011-09-21
RU2558302C2 (ru) 2015-07-27

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