CN102772601B - External medicine for treating facial paralysis and preparation method thereof - Google Patents

Abstract

The invention discloses an external medicine for treating facial paralysis and a preparation method thereof. The external medicine is mainly prepared from notopterygium root, radix peucedani, bombyx batryticatus, mint, radix clematidis, folium artemisiae argyi and the like according to certain weight proportions. The medicine disclosed by the invention has the functions of dispersing wind and dispelling pathogen, dredging channels and activating collaterals and removing toxicity, is used for treating facial paralysis, takes an effect quickly, and has a good curative effect and a high cure rate.

Description

External used medicine of a kind of facial paralysis and preparation method thereof

Technical field

The present invention relates to external used medicine of a kind of facial paralysis and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Facial paralysis also is facial neuritis, refers to nervus facialis and benumbs, and a kind of common disease that dyskinesia is principal character appears in the muscle of facial expression group.Facial neuritis all can be fallen ill at all seasons.This patient's main clinical manifestation is facial muscle paralysis, the volume stricture of vagina shoals or disappearance, palpebral fissure increase, can not be closed, the tear outflow, nasolabial fold shoals or it is smooth to become, ptosis of labial angle, can not frown, the drum cheek and whistle etc.The traditional Chinese medical science thinks, facial neuritis belongs to the category of " apoplexy ", how because of human righteousness's deficiency, and the venation inanition, ailment said due to cold or exposure is invaded venation in an opponent's defence, thereby causes the resistance of QI and blood numbness, and the muscle arteries and veins relaxes and falls ill.At present, western medical treatment is main mainly with medicine and operative treatment, and the long-term taking medicine can cause very large infringement to Liver and kidney, and operation wound is large, the unsuccessful leeway that there is no redemption.Therefore, there is great demand in people to the Chinese medicine of effective facial paralysis.

Summary of the invention

The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective facial paralysis, thereby has completed the present invention.

Purpose of the present invention just is to provide a kind of composition of medicine that can facial paralysis.

Another object of the present invention just has been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects Rhizoma Et Radix Notopterygii, Radix Peucedani, Bombyx Batryticatus, Herba Menthae, Herba Schizonepetae, Periostracum Cicadae, Radix Clematidis, Radix Saposhnikoviae, Radix Aconiti Lateralis Preparata, Folium Artemisiae Argyi, Scorpio, Borneolum Syntheticum and Arisaema Cum Bile crude drug to be combined, make each efficacy of drugs produce synergism these drug regimens, thus effective facial paralysis.Wherein select Rhizoma Et Radix Notopterygii to be because its nature and flavor are arduous, temperature, enter bladder, kidney channel, and loose exterior cold is arranged, wind-damp dispelling, and the function in sharp joint, the wind and cold that cures cold, have a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select Radix Peucedani to be because its nature and flavor are hot, bitter, be slightly cold, return lung meridian, loose wind heat clearing away is arranged, the function of lowering the adverse-rising QI to resolve phlegm, control the cough due to pathogenic wind-heat, abundant expectoration, and the expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.Select Bombyx Batryticatus to be because its nature and flavor are hot, salty, flat, return liver, lung meridian.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.For the apoplexy facial hemiparalysis, infantile convulsion is twitched, and head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.Selecting Herba Menthae is because its nature and flavor suffering, cool, enters lung, Liver Channel, and dispelling wind is arranged, and heat radiation is warded off dirtyly, and the function of removing toxic substances, control affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Selecting Herba Schizonepetae is that temperature, enter lung, Liver Channel, delivers because of its nature and flavor suffering, dispel the wind, and the function for the treatment of blood disorders, the parch to black hemostasis, the heating that cures cold, headache, laryngopharynx swelling and pain, the apoplexy locked mouth, spit blood, and epistaxis, have blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Selecting Periostracum Cicadae is because its property sweet-salty, cool, enters lung, Liver Channel, and loose wind heat is arranged, and lung qi dispersing determine the function of convulsion, controls affection due to external wind and heat, the cough hoarseness, and measles is thoroughly not smooth, the rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Select Radix Clematidis to be because its nature and flavor suffering is salty, temperature, poisonous, enter urinary bladder channel, wind-damp dispelling is arranged, the meridian dredging, expectorant saliva, the function of the loose hypochondriac lump, control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria ， lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Selecting Radix Saposhnikoviae is that temperature, enter bladder, lung, spleen channel, delivers because of its property acrid-sweet flavor, dispels the wind, and victory is wet, and the function of pain relieving, control affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, and anemofrigid-damp arthralgia, joint is ached, and the extremity contraction is anxious, tetanus.Selecting Radix Aconiti Lateralis Preparata is because of its property acrid-sweet flavor, and heat is poisonous, enter the heart, spleen, kidney channel, have recuperating depleted YANG to mend fire, the function of dispelling cold and removing dampness, control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, the contracture of anemofrigid-damp arthralgia ， Wei lame, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.Folium Artemisiae Argyi nature and flavor toil, temperature.Enter spleen, liver, kidney channel.The blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery, tell nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Select Scorpio to be because the salty suffering of its nature and flavor is flat, poisonous, enter meridian of Foot-JUE YIN, dispel the wind, relieving convulsion, dredging collateral, the function of removing toxic substances, control convulsion with spasms ， epilepsy, apoplexy, hemiplegia, deviation of the eye and mouth, migraine, rheumatic arthralgia, tetanus, tuberculous lymphadenitis, the rubella skin ulcer is swollen.Select Borneolum Syntheticum to be because its nature and flavor are arduous, cool, enter the heart, lung meridian, logical all keys are arranged, loose stagnated fire, removing nebula improving eyesight, the function of reducing swelling and alleviating pain, control the apoplexy locked mouth, calentura coma ， Jing Epilepsy expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, conjunctivitis, enterobiasis.Select Arisaema Cum Bile to be because its nature and flavor hardship is cool in nature, enter the heart, liver, lung three warps, clearing away fire and eliminating phlegm is arranged, the relieving convulsion Epilepsy of Dinging, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.

The specific embodiment

The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope

Rhizoma Et Radix Notopterygii 15-40 gram Radix Peucedani 10-25 gram Bombyx Batryticatus 5-15 gram

Herba Menthae 10-18 gram Herba Schizonepetae 20-45 gram Periostracum Cicadae 4-18 gram

Radix Clematidis 20-40 gram Radix Saposhnikoviae 10-25 gram Radix Aconiti Lateralis Preparata 8-20 gram

Folium Artemisiae Argyi 10-20 gram Scorpio 5-17 gram Borneolum Syntheticum 5-12 gram

Arisaema Cum Bile 8-20 gram

Wherein, be preferably

Rhizoma Et Radix Notopterygii 30 gram Radix Peucedani 15 gram Bombyx Batryticatus 10 grams

Herba Menthae 15 gram Herba Schizonepetae 30 gram Periostracum Cicadae 10 grams

Radix Clematidis 30 gram Radix Saposhnikoviae 15 gram Radix Aconiti Lateralis Preparata 10 grams

Folium Artemisiae Argyi 15 gram Scorpio 10 gram Borneolum Syntheticum 10 grams

Arisaema Cum Bile 15 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section, dry;

2, Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;

3, Bombyx Batryticatus: get crude drug, remove residual silk, impurity;

4, Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;

5, Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;

6, Periostracum Cicadae: choose decontamination, clean and dry;

7, Radix Clematidis: choose clean impurity, remove residual stem, be soaked in water, pull out and run through, cutting, dry;

8, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;

9, Radix Aconiti Lateralis Preparata: get Radix Aconiti Lateralis Preparata and float with water logging, change water 2-3 every day, to saline taste, floats most, take out, add water with the well-done heart with Radix Glycyrrhizae, Semen sojae atricolor, when cutting deutostoma and taste without numb feeling in the tongue, take out, remove Radix Glycyrrhizae, Semen sojae atricolor, shave, drying, sieve removes chip (every 100 jin of Radix Aconiti Lateralis Preparata, with 5 jin, Radix Glycyrrhizae, 10 jin, Semen sojae atricolor);

10, Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

11, Scorpio: clear water floats the matter that desalts, and dry, or the low baking temperature roasting is used;

12, Borneolum Syntheticum: original is used as medicine;

13, Arisaema Cum Bile: get crude drug, choose decontamination.

Two, preparation

1, the Rhizoma Et Radix Notopterygii of described weight, Radix Peucedani, Bombyx Batryticatus, Herba Menthae, Herba Schizonepetae, Periostracum Cicadae, Radix Clematidis, Radix Saposhnikoviae, Radix Aconiti Lateralis Preparata, Folium Artemisiae Argyi, Scorpio, Borneolum Syntheticum, Arisaema Cum Bile are put into to medicinal cupping and added water qdx immersion 5-10 minute, with little fire, decoct 15～20 minutes, the extracting juice that removes slag, obtain medicinal liquid.

Medicine of the present invention has the function of the loose heresy of dispelling wind, dredge the meridian passage, removing toxic substances, is used for the treatment of the facial paralysis instant effect, good effect, and cure rate is high.

The specific embodiment

Below further set forth the beneficial effect of medicine of the present invention by test example, these test examples comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get 10 of new zealand rabbits, male and female dual-purpose, body weight 2.0-2.5kg, to test with the rabbit belly wool and clean out, and micro-broken to epidermis with hcl corrosion, by the external application of medicinal liquor affected part, every day 2 times, connect and apply 4 days, observe the administration reaction every day, injury incrustation after 2-3 days, decrustation after 8 days, result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation of [test example 2] Drug therapy facial paralysis of the present invention

1, physical data

Accept out-patient's 220 examples for medical treatment.

2, diagnostic criteria

Disease side surface part expression skin hemiplegia is crooked, and the forehead wrinkle disappears, palpebral fissure enlarges, nasolabial fold is smooth, ptosis of labial angle, and in the time of grinningly, bicker, to askew the increasing the weight of of strong lateral deviation, can not be made the wrinkle volume, frown, closes order, air-blowing and the action such as be in a pout.When rousing the cheek and whistling, because the Ipsilateral lip can not closed leak gas.

3, Therapeutic Method

By putting into thermos flask after medicine liquid heating, cover in head with towel, the Ipsilateral face is aimed to bottleneck, with steam, smoke about 20 minutes, after medicinal liquid is slightly cool, available towel dips medicinal liquid and cleans Ipsilateral Head And Face 5-10 minute, every day, medication was 3-5 time, within 10 days, was 1 course for the treatment of, continuously 2-3 the course for the treatment of.

4, efficacy assessment standard

Produce effects: clinical symptom disappearance after treatment, it is normal that face nerve recovers, and follows up a case by regular visits to after 6 months without the recidivist;

Take a turn for the better: clinical symptoms is obviously improved, and face nerve progressively recovers;

Invalid: clinical partial symptoms disappears or, without change, does not reach improvement standard person.

5, therapeutic outcome

In above-mentioned treatment, by Drug therapy facial paralysis patient of the present invention 220 examples, produce effects 190 examples as a result, obvious effective rate is 86.36%, 13 examples that take a turn for the better, improvement rate is 5.90%, invalid 17 examples, total effective rate is 92.27%.

Claims (3)

1. the external used medicine of a facial paralysis, it is characterized in that: it is made by the crude drug in the following weight scope:

Rhizoma Et Radix Notopterygii 15-40 gram Radix Peucedani 10-25 gram Bombyx Batryticatus 5-15 gram

Herba Menthae 10-18 gram Herba Schizonepetae 20-45 gram Periostracum Cicadae 4-18 gram

Radix Clematidis 20-40 gram Radix Saposhnikoviae 10-25 gram Radix Aconiti Lateralis Preparata 8-20 gram

Folium Artemisiae Argyi 10-20 gram Scorpio 5-17 gram Borneolum Syntheticum 5-12 gram

Arisaema Cum Bile 8-20 gram.

2. external used medicine according to claim 1, wherein the consumption of each crude drug is:

Rhizoma Et Radix Notopterygii 30 gram Radix Peucedani 15 gram Bombyx Batryticatus 10 grams

Herba Menthae 15 gram Herba Schizonepetae 30 gram Periostracum Cicadae 10 grams

Radix Clematidis 30 gram Radix Saposhnikoviae 15 gram Radix Aconiti Lateralis Preparata 10 grams

Folium Artemisiae Argyi 15 gram Scorpio 10 gram Borneolum Syntheticum 10 grams

Arisaema Cum Bile 15 grams.

3. according to the preparation method of claim 1 or 2 described medicine, it is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section, dry;

(2) Radix Peucedani: get crude drug, remove impurity, clean, run through, shave, drying or cold drying, sieve removes chip;

(3) Bombyx Batryticatus: get crude drug, remove residual silk, impurity;

(4) Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;

(5) Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;

(6) Periostracum Cicadae: choose decontamination, clean and dry;

(7) Radix Clematidis: choose clean impurity, remove residual stem, be soaked in water, pull out and run through, cutting, dry;

(8) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;

(9) Radix Aconiti Lateralis Preparata: get Radix Aconiti Lateralis Preparata and float with water logging, change water 2-3 every day, to saline taste, floats most, take out, with Radix Glycyrrhizae, Semen sojae atricolor, add water with the well-done heart, when cutting deutostoma and taste without numb feeling in the tongue, take out, remove Radix Glycyrrhizae, Semen sojae atricolor, shave, drying, sieve removes chip, every 100 jin of Radix Aconiti Lateralis Preparata, with 5 jin, Radix Glycyrrhizae, 10 jin, Semen sojae atricolor;

(10) Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;

(11) Scorpio: clear water floats the matter that desalts, and dry, or the low baking temperature roasting is used;

(12) Borneolum Syntheticum: original is used as medicine;

(13) Arisaema Cum Bile: get crude drug, choose decontamination;

(2) preparation

The Rhizoma Et Radix Notopterygii of described weight, Radix Peucedani, Bombyx Batryticatus, Herba Menthae, Herba Schizonepetae, Periostracum Cicadae, Radix Clematidis, Radix Saposhnikoviae, Radix Aconiti Lateralis Preparata, Folium Artemisiae Argyi, Scorpio, Borneolum Syntheticum, Arisaema Cum Bile are put into to medicinal cupping and add water qdx immersion 5-10 minute, with little fire, decoct 15～20 minutes, the extracting juice that removes slag, obtain medicinal liquid.