CN102770441A - Tmem22肽及包含它们的疫苗 - Google Patents
Tmem22肽及包含它们的疫苗 Download PDFInfo
- Publication number
- CN102770441A CN102770441A CN2010800638296A CN201080063829A CN102770441A CN 102770441 A CN102770441 A CN 102770441A CN 2010800638296 A CN2010800638296 A CN 2010800638296A CN 201080063829 A CN201080063829 A CN 201080063829A CN 102770441 A CN102770441 A CN 102770441A
- Authority
- CN
- China
- Prior art keywords
- tmem22
- peptide
- seq
- peptides
- hla
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28621309P | 2009-12-14 | 2009-12-14 | |
| US61/286,213 | 2009-12-14 | ||
| US28765009P | 2009-12-17 | 2009-12-17 | |
| US61/287,650 | 2009-12-17 | ||
| US32638010P | 2010-04-21 | 2010-04-21 | |
| US61/326,380 | 2010-04-21 | ||
| PCT/JP2010/007228 WO2011074236A1 (en) | 2009-12-14 | 2010-12-13 | Tmem22 peptides and vaccines including the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102770441A true CN102770441A (zh) | 2012-11-07 |
Family
ID=44167006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800638296A Pending CN102770441A (zh) | 2009-12-14 | 2010-12-13 | Tmem22肽及包含它们的疫苗 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8697631B2 (https=) |
| EP (1) | EP2513136A4 (https=) |
| JP (1) | JP2013513549A (https=) |
| KR (1) | KR20120104350A (https=) |
| CN (1) | CN102770441A (https=) |
| AU (1) | AU2010331648A1 (https=) |
| BR (1) | BR112012014345A2 (https=) |
| CA (1) | CA2782977A1 (https=) |
| IL (1) | IL220146A0 (https=) |
| MX (1) | MX2012006770A (https=) |
| RU (1) | RU2012130015A (https=) |
| SG (2) | SG10201408245WA (https=) |
| TW (1) | TW201136604A (https=) |
| WO (1) | WO2011074236A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9890202B2 (en) | 2010-07-19 | 2018-02-13 | Yeda Research And Development Co. Ltd. | Peptides based on the transmembrane domain of a toll-like receptor (TLR) for treatment of TLR-mediated diseases |
| EP2766384B1 (en) * | 2011-10-10 | 2016-11-23 | Yeda Research and Development Co. Ltd. | Toll-like receptor 4 (tlr-4) agonist peptides for modulating tlr-4 mediated immune response |
| BR112015012234A2 (pt) * | 2012-12-04 | 2017-08-15 | Oncotherapy Science Inc | Peptídios sema5b e vacinas contendo os mesmos |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998041539A2 (en) * | 1997-03-19 | 1998-09-24 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| CN101365806A (zh) * | 2005-12-01 | 2009-02-11 | 医学预后研究所 | 用于鉴定治疗反应的生物标记的方法和装置及其预测疗效的用途 |
| WO2009117196A1 (en) * | 2008-02-15 | 2009-09-24 | Pacific Arrow Limited | Blocking the metastasis of cancer cells and the uses of new compounds thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
| WO1997005900A1 (en) | 1995-08-03 | 1997-02-20 | Rijksuniversiteit Te Leiden | Cell derived antigen presenting vesicles |
| US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
| JP2000516090A (ja) | 1996-07-26 | 2000-12-05 | スローン―ケッタリング インスティチュート フォー キャンサー リサーチ | 遺伝子的免疫化のための方法と試薬 |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| JP4413429B2 (ja) | 1998-06-25 | 2010-02-10 | 株式会社グリーンペプタイド | サイクロフィリンb由来の腫瘍抗原ペプチド |
| DK2336167T3 (da) | 2001-03-14 | 2019-09-02 | Dako Denmark As | MHC-molekylkonstrukter og deres anvendelse til diagnose og terapi |
| CA2399569A1 (en) | 2001-09-25 | 2003-03-25 | Yusuke Nakamura | Diagnostic markers and drug targets for treatment of cancer |
| GB2392158B (en) | 2002-08-21 | 2005-02-16 | Proimmune Ltd | Chimeric MHC protein and oligomer thereof |
| DE60327786D1 (de) | 2002-09-12 | 2009-07-09 | Oncotherapy Science Inc | Kdr-peptide und diese enthaltende impfstoffe |
| WO2006031221A1 (en) | 2004-09-13 | 2006-03-23 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Compositions comprising t cell receptors and methods of use thereof |
| WO2007013575A2 (en) | 2005-07-28 | 2007-02-01 | Oncotherapy Science, Inc. | Method for diagnosing and treating renal cell carcinoma |
| JP5276846B2 (ja) | 2005-09-13 | 2013-08-28 | 国立大学法人三重大学 | T細胞レセプターをコードする核酸が挿入されてなるベクター及び該レセプターを発現する細胞 |
| TW201425333A (zh) * | 2007-04-11 | 2014-07-01 | Oncotherapy Science Inc | 腫瘤血管內皮標誌8胜肽及包含此胜肽之疫苗 |
| TW200932260A (en) * | 2007-11-28 | 2009-08-01 | Oncotherapy Science Inc | STAT3 epitope peptides |
-
2010
- 2010-12-10 TW TW099143200A patent/TW201136604A/zh unknown
- 2010-12-13 EP EP20100837268 patent/EP2513136A4/en not_active Withdrawn
- 2010-12-13 AU AU2010331648A patent/AU2010331648A1/en not_active Abandoned
- 2010-12-13 BR BR112012014345A patent/BR112012014345A2/pt not_active IP Right Cessation
- 2010-12-13 SG SG10201408245WA patent/SG10201408245WA/en unknown
- 2010-12-13 JP JP2012527547A patent/JP2013513549A/ja active Pending
- 2010-12-13 WO PCT/JP2010/007228 patent/WO2011074236A1/en not_active Ceased
- 2010-12-13 CA CA2782977A patent/CA2782977A1/en not_active Abandoned
- 2010-12-13 KR KR1020127018341A patent/KR20120104350A/ko not_active Withdrawn
- 2010-12-13 US US13/515,656 patent/US8697631B2/en not_active Expired - Fee Related
- 2010-12-13 RU RU2012130015/10A patent/RU2012130015A/ru not_active Application Discontinuation
- 2010-12-13 CN CN2010800638296A patent/CN102770441A/zh active Pending
- 2010-12-13 MX MX2012006770A patent/MX2012006770A/es active IP Right Grant
- 2010-12-13 SG SG2012041471A patent/SG181530A1/en unknown
-
2012
- 2012-06-04 IL IL220146A patent/IL220146A0/en unknown
-
2014
- 2014-03-21 US US14/221,721 patent/US20140199336A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998041539A2 (en) * | 1997-03-19 | 1998-09-24 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| CN101365806A (zh) * | 2005-12-01 | 2009-02-11 | 医学预后研究所 | 用于鉴定治疗反应的生物标记的方法和装置及其预测疗效的用途 |
| WO2009117196A1 (en) * | 2008-02-15 | 2009-09-24 | Pacific Arrow Limited | Blocking the metastasis of cancer cells and the uses of new compounds thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2012130015A (ru) | 2014-01-27 |
| SG181530A1 (en) | 2012-07-30 |
| US20140199336A1 (en) | 2014-07-17 |
| EP2513136A4 (en) | 2013-06-19 |
| IL220146A0 (en) | 2012-07-31 |
| JP2013513549A (ja) | 2013-04-22 |
| CA2782977A1 (en) | 2011-06-23 |
| EP2513136A1 (en) | 2012-10-24 |
| SG10201408245WA (en) | 2015-01-29 |
| TW201136604A (en) | 2011-11-01 |
| US8697631B2 (en) | 2014-04-15 |
| WO2011074236A1 (en) | 2011-06-23 |
| AU2010331648A1 (en) | 2012-06-21 |
| KR20120104350A (ko) | 2012-09-20 |
| BR112012014345A2 (pt) | 2017-01-10 |
| MX2012006770A (es) | 2012-07-20 |
| US20120308591A1 (en) | 2012-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20121107 |