CN102762202A - 紫杉烷前-乳剂制剂以及制备和使用其的方法 - Google Patents

紫杉烷前-乳剂制剂以及制备和使用其的方法 Download PDF

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Publication number
CN102762202A
CN102762202A CN2011800094323A CN201180009432A CN102762202A CN 102762202 A CN102762202 A CN 102762202A CN 2011800094323 A CN2011800094323 A CN 2011800094323A CN 201180009432 A CN201180009432 A CN 201180009432A CN 102762202 A CN102762202 A CN 102762202A
Authority
CN
China
Prior art keywords
emulsion
taxane
pro
emulsion preparations
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800094323A
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English (en)
Chinese (zh)
Inventor
锅田喜一郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Pharma USA Inc
Original Assignee
Techno Guard Co Ltd
Teikoku Pharma USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Techno Guard Co Ltd, Teikoku Pharma USA Inc filed Critical Techno Guard Co Ltd
Publication of CN102762202A publication Critical patent/CN102762202A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2011800094323A 2010-02-19 2011-02-18 紫杉烷前-乳剂制剂以及制备和使用其的方法 Pending CN102762202A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30631510P 2010-02-19 2010-02-19
US61/306,315 2010-02-19
PCT/US2011/025418 WO2011103413A2 (en) 2010-02-19 2011-02-18 Taxane pro-emulsion formulations and methods making and using the same

Publications (1)

Publication Number Publication Date
CN102762202A true CN102762202A (zh) 2012-10-31

Family

ID=44477026

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800094323A Pending CN102762202A (zh) 2010-02-19 2011-02-18 紫杉烷前-乳剂制剂以及制备和使用其的方法

Country Status (9)

Country Link
US (2) US8569357B2 (enExample)
EP (1) EP2536407A4 (enExample)
JP (1) JP2013520435A (enExample)
KR (1) KR20120126072A (enExample)
CN (1) CN102762202A (enExample)
AU (1) AU2011217951B2 (enExample)
IN (1) IN2012DN05888A (enExample)
TW (1) TWI438009B (enExample)
WO (1) WO2011103413A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ702242A (en) * 2012-05-31 2016-03-31 Asahi Kasei Pharma Corp Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent
JO3685B1 (ar) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent

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WO2007082978A1 (es) * 2006-01-20 2007-07-26 Eriochem S.A. Una formulación farmacéutica de taxano, una composición sólida de taxano, un procedimiento para la preparación de dicha composición sólida de taxano, una composición solubilizante de dicha composición sólida de taxano, y un conjunto de elementos (kit) par
CN101094646A (zh) * 2004-09-28 2007-12-26 陈献 用于输送紫杉烷及其它不溶性药物的低油乳剂组合物
WO2008105852A2 (en) * 2006-10-26 2008-09-04 Creighton University Mucoadhesive nanoparticles for cancer treatment
CN101428002A (zh) * 2008-11-20 2009-05-13 沈阳万爱普利德医药科技有限公司 注射用紫杉醇冻干微乳剂及其制备方法

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WO1998030205A1 (en) * 1997-01-07 1998-07-16 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
WO2000050007A1 (en) * 1999-02-26 2000-08-31 Lipocine, Inc. Compositions and methods for improved delivery of hydrophobic therapeutic agents
CN1823737A (zh) * 1999-05-27 2006-08-30 阿库斯菲尔公司 多孔药物基质及其制造方法
US20030099674A1 (en) * 2001-08-11 2003-05-29 Chen Andrew X. Lyophilized injectable formulations containing paclitaxel or other taxoid drugs
US20060078618A1 (en) * 2001-12-11 2006-04-13 Constantinides Panayiotis P Lipid particles and suspensions and uses thereof
CN101094646A (zh) * 2004-09-28 2007-12-26 陈献 用于输送紫杉烷及其它不溶性药物的低油乳剂组合物
WO2007082978A1 (es) * 2006-01-20 2007-07-26 Eriochem S.A. Una formulación farmacéutica de taxano, una composición sólida de taxano, un procedimiento para la preparación de dicha composición sólida de taxano, una composición solubilizante de dicha composición sólida de taxano, y un conjunto de elementos (kit) par
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Also Published As

Publication number Publication date
AU2011217951B2 (en) 2013-07-11
WO2011103413A2 (en) 2011-08-25
TWI438009B (zh) 2014-05-21
KR20120126072A (ko) 2012-11-20
IN2012DN05888A (enExample) 2015-09-18
AU2011217951A1 (en) 2012-07-19
US20110207803A1 (en) 2011-08-25
EP2536407A4 (en) 2013-08-14
JP2013520435A (ja) 2013-06-06
WO2011103413A3 (en) 2012-01-12
US8569357B2 (en) 2013-10-29
US20140088181A1 (en) 2014-03-27
TW201141538A (en) 2011-12-01
EP2536407A2 (en) 2012-12-26

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