CN102755553B - Sinkiang arnebia root-honeysuckle flower-red paeony root-Chinese arborvitae twig soup for treating allergic purpura - Google Patents

Abstract

The invention relates to the field of medicament formulas, in particular to sinkiang arnebia root-honeysuckle flower-red paeony root-Chinese arborvitae twig soup for treating allergic purpura. The soup is characterized by consisting of the following bulk pharmaceuticals in percentage by weight: 5-8 percent of inkiang arnebia root, 8-11 percent of honeysuckle flower, 7-9 percent of red paeony root, 5-7 percent of Chinese arborvitae twig, 5-7 percent of tree peony bark, 4-6 percent of crude rehmannia, 4-6 percent of fineleaf schizonepeta herb, 3-6 percent of divaricate saposhnikovia root, 3-6 percent of figwort, 5-7 percent of dwarf lilyturf root, 3-5 percent of Chinese atractylodes, 8-11 percent of cogongrass rhizome, 4-7 percent of red-rooted salvia root, 2-4 percent of liquoric root, 2-4 percent of pseudo-ginseng root powder, 6-9 percent of paniculate swallowwort root and 4-7 percent of lightyellow sophora root. A preparation method of the soup comprises the following steps of: packaging pseudo-ginseng root powder separately; soaking the other 16 types of bulk pharmaceuticals into water and decocting; and removing residues to obtain a filtrate, and adding pseudo-ginseng root powder to obtain sinkiang arnebia root-honeysuckle flower-red paeony root-Chinese arborvitae twig soup. The soup is low in cost, has a good curative effect on allergic purpura, is free from toxic and side effects, has the effects of detoxifying, promoting eruption, clearing heat, removing ecchymoses, cooling wind-heat, cooling blood, arresting bleeding and the like, and is suitable for simple type, joint type, abdominal type, kidney type and mixed type allergic purpura.

Description

The purple silver-colored red cypress soup that is used for anaphylactoid purpura

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of purple silver-colored red cypress soup for anaphylactoid purpura.

Background technology

As everyone knows, anaphylactoid purpura is that a kind of allergy blood capillary and minute blood vessel are scorching, it is characterized by non-thrombocytopenic skin purpura, can be with arthralgia, and stomachache and nephropathy.Its cause of disease is complicated, and antibacterial, virus, food and medicine etc. all can cause morbidity, and malignant tumor and autoimmune disease also can be may the cause of disease.Pathogenesis may be the allergy of III type, antigen-antibody deposits in blood vessel wall in conjunction with the circulating immune complex that forms, and activating complement causes blood capillary and little blood vessel wall and produces inflammation on every side, Vascular Permeability is increased, thereby produce various clinical manifestations.Clinical child and the teenager be more common in, the male is apt to occur in lower limb more than the women, stretches side as main take shank, and severe one can involve upper limb, trunk.The premorbid patient has the prodromes such as upper respiratory tract infection, low grade fever, general malaise, the needle point sample then occurs to Semen Glycines large palp petechia or ecchymosis, and part has the tendency of fusion, often occurs in batches, and the course of disease is different in size, but a few days or 1～2 year, easily recurrence.Severe patient can be had blood in stool, even intussusception, perforation occur.Be called the kidney type such as concurrent kidney damage, the renal function injury of varying degree can appear in minority.It is very difficult that clinical treatment is sought reason, mainly is anti symptom treatment and gives glucocorticoid, very large to actual bodily harm.

Summary of the invention

Technical problem to be solved by this invention is in order to overcome the deficiencies in the prior art, a kind of purple silver-colored red cypress soup for anaphylactoid purpura is provided, cost is low, treatment anaphylactoid purpura curative effect is high, have no side effect, have the effects such as detoxifcation rash, heat clearing away speckle removing, wind-heat dissipating, cooling blood for hemostasis, be applicable to simple type, joint type, abdomen type, kidney type and mixed type anaphylactoid purpura.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of purple silver-colored red cypress soup for anaphylactoid purpura, it is characterized in that, each crude drug forms, Radix Arnebiae (Radix Lithospermi) 5～8%, Flos Lonicerae 8～11%, Radix Paeoniae Rubra 7～9%, Cacumen Platycladi 5～7%, Cortex Moutan 5～7%, Radix Rehmanniae 4～6%, Herba Schizonepetae 4～6%, Radix Saposhnikoviae 3～6%, Radix Scrophulariae 3～6%, Radix Ophiopogonis 5～7%, Radix Rubiae 3～5%, Rhizoma Imperatae 8～11%, Radix Salviae Miltiorrhizae 4～7%, Radix Glycyrrhizae 2～4%, Radix Notoginseng powder 2～4%, Radix Cynanchi Paniculati 6～9%, Radix Sophorae Flavescentis 4～7%, at first with Radix Notoginseng powder list bag, the 16 flavor crude drug of Yuing are soaked in water, decoct, remove slag to such an extent that add again Radix Notoginseng powder after the filtrate, namely make purple silver-colored red cypress soup.

The invention has the beneficial effects as follows that cost is low, treatment anaphylactoid purpura curative effect is high, has no side effect, and has the effects such as detoxifcation rash, heat clearing away speckle removing, wind-heat dissipating, cooling blood for hemostasis, is applicable to simple type, joint type, abdomen type, kidney type and mixed type anaphylactoid purpura.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1: adopting Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Radix Paeoniae Rubra, Cacumen Platycladi, Cortex Moutan, Radix Rehmanniae, Herba Schizonepetae, Radix Saposhnikoviae, Radix Scrophulariae, Radix Ophiopogonis, Radix Rubiae, Rhizoma Imperatae, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Radix Notoginseng powder, Radix Cynanchi Paniculati, Radix Sophorae Flavescentis is that raw material is prepared from.The every pair of its component (% by weight) is Radix Arnebiae (Radix Lithospermi) 6.8, Flos Lonicerae 9.8, Radix Paeoniae Rubra 8.5, Cacumen Platycladi 5.3, Cortex Moutan 6.4, Radix Rehmanniae 5.9, Herba Schizonepetae 5.7, Radix Saposhnikoviae 5.3, Radix Scrophulariae 4.8, Radix Ophiopogonis 6.1, Radix Rubiae 4.1, Rhizoma Imperatae 9.2, Radix Salviae Miltiorrhizae 5.5, Radix Glycyrrhizae 2.4, Radix Notoginseng powder 2.2, Radix Cynanchi Paniculati 7.1, Radix Sophorae Flavescentis 4.9.Get above-mentioned 17 flavor raw material gross weights, 150 grams, at first with Radix Notoginseng powder list bag, at room temperature above-mentioned 16 flavors of Yuing are added water 1000～1200ml, soaked 3～4 hours, and then boiled with high heat slow fire and decoct to 60 minutes, filtrate 250ml removes slag to get, medicinal residues add water 250～300ml again and decoct about 30 minutes, the filtrate 50ml that removes slag to get to get the 300ml medicine juice, in the aseptic vial of packing into altogether, pour again single bag Radix Notoginseng powder into, mix homogeneously namely makes purple silver-colored red cypress soup, and seal bottle cap is for subsequent use.1 dose of every day, every natural gift 2 times are oral, each (medicine) being taken before meal 100ml, and the every bu of remaining 100ml medicine juice 2 times dips medicine juice with aseptic cotton carrier and embrocates the affected part, orally embrocates medicine juice with pars affecta skin and carries out synchronously.7 days is a course for the treatment of, has a rest 3～5 days, carries out next course for the treatment of again, generally uses 3～5 courses for the treatment of.

Principal agent Radix Arnebiae (Radix Lithospermi) decoct of the present invention has the refrigeration function of mitigation, and the effect of obvious inhibition Mouse Oestrous Cycle and fertility is arranged, and obvious anti-pituitary gonadotropic hormone and anti-chorionic-gonadotropin hormone effect are arranged.The dermatophytess such as acrothesium floccosum, ulotrichy budlet spore tinea bacterium all there is inhibitory action.Nature and flavor are sweet, salty, cold, GUIXIN, Liver Channel.Have removing heat from blood, the rash effect of invigorating blood circulation, detoxify, be used for that heat in blood, poison are contained, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire.The Flos Lonicerae bacteriostatic test all has inhibitory action to staphylococcus aureus, Staphylococcus albus and beta hemolytic streptococcus etc., can be combined with cholesterol, thereby reduces intestinal to the absorption of cholesterol, and the leukocytes phagocytic of promotion etc. is arranged.Nature and flavor are sweet, cold, return lung, the heart, stomach warp.Have heat-clearing and toxic substances removing, wind-heat dissipating effect, be used for carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.The Radix Paeoniae Rubra nature and flavor are bitter, be slightly cold, return Liver Channel.Have heat clearing away, removing heat from blood, eliminating stasis to stop pain effect, be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, WEIJIA stomachache, injury from falling down, carbuncle skin infection.The Cacumen Platycladi nature and flavor are bitter, puckery, cold, return lung, liver, spleen channel.Have cooling blood for hemostasis, the growing and blacking hair effect is used for hematemesis and epistaxis, spits blood, has blood in stool, metrostaxis, heat in blood alopecia, early whitening of beard and hair.The Cortex Moutan nature and flavor are bitter, hot, be slightly cold GUIXIN, liver, kidney channel.Have clearing away heat and cooling blood, blood circulation invigorating efficacies, be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus etc.The Radix Rehmanniae nature and flavor are sweet, cold, GUIXIN, liver, kidney channel.Have clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid, be used for that calentura, crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, hematemesis and epistaxis, send out the speckle dermexanthesis.Hot, the tepor of Herba Schizonepetae nature and flavor is returned lung, Liver Channel, has the loose wind that induces sweat, the rash effect, be used for flu, headache, measles, rubella, skin infection from the beginning of.The Radix Saposhnikoviae nature and flavor are hot, sweet, warm, return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win wet, relieving convulsion effect, be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.The Radix Scrophulariae nature and flavor are sweet, bitter, salty, be slightly cold, and return lung, stomach, kidney channel.Have removing heat from blood YIN nourishing, eliminating fire and detoxication effect.Hinder constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion pharyngalgia, scrofula, diphtheria etc. for calentura impairment of YANG, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin.Sweet, the little hardship of nature and flavor Radix Ophiopogonis, be slightly cold GUIXIN, lung, stomach warp.Have YIN nourishing and the production of body fluid promoting, the lung moistening effect that clears away heart-fire, be used for that dryness of the lung dry cough, chronic consumptive disease cough, thirsty, the vexed insomnia of Tianjin wound, interior-heat are quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.The Radix Rubiae nature and flavor are bitter, tremble with fear, return Liver Channel.Have removing heat from blood, hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow, be used for haematemesis, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.The Rhizoma Imperatae nature and flavor are sweet, cold, return lung, stomach, urinary bladder channel.Have cooling blood for hemostasis, clearing away heat and promoting diuresis effect.Be used for heat in blood haematemesis, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria etc.The Radix Salviae Miltiorrhizae nature and flavor are bitter, be slightly cold GUIXIN, Liver Channel.Have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the relieving restlessness effect clears away heart-fire.Be used for that menoxenia, amenorrhea dysmenorrhea, pyretic arthralgia pain, dysphoria and insomnia, WEIJIA are gathered, skin infection swells and ache etc.The Radix Glycyrrhizae nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp.Have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription effect.Be used for that spleen, insufficiency of stomach are weak, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, cushion toxicity, strong etc.Sweet, the little hardship of Radix Notoginseng powder nature and flavor, temperature are returned liver, stomach warp.Have dissipating blood stasis hemostasis, subduing swelling and relieving pain effect, be used for spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage etc.The Radix Cynanchi Paniculati nature and flavor are hot, warm, return liver, stomach warp.Have the removing dampness of dispeling the wind, antalgesic-antipruritic effect, be used for rheumatic arthralgia, stomachache distension, urticaria, eczema etc.The Radix Sophorae Flavescentis nature and flavor are bitter, cold, GUIXIN, liver, stomach, large intestine, urinary bladder channel.Have the effects such as heat clearing and damp drying, be used for hematodiarrhoea, have blood in stool, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies, leprosy etc.The ingenious prescription of 17 flavor Chinese herbal medicine, reasonable compatibility increases principal agent and the identical or close curative effect of medication of function, alleviates or the disappearance toxic and side effects, promotes that erythra disappears early, improves capillary fragility, improves immunity of organism and antiinflammatory action.

But each raw material of the present invention also embodiment of the listed ratio of according to the form below (percentage by weight) mixing is realized.Its processing technique is identical with embodiment 1.

Be that the present invention is described in further detail for the clinical trial carried out of In Shandong Weihai Wendeng City central hospital below in conjunction with my institute:

1. case is selected: select to meet the 7th edition diagnostic criteria of " skin cypridology " " anaphylactoid purpura " of Zhang Xuejun chief editor.Choose at random 64 examples, male 39 examples, women 25 examples, age 13-39 year, simple type 19 examples wherein, joint type 14 examples, abdomen type 18 examples, kidney type 6 examples, mixed type 7 examples, the 5-60 days course for the treatment of, average 39 days.

2. Therapeutic Method: 1 dose minute every day 2 times is oral, each (medicine) being taken before meal 100ml, and the every bu of remaining 100ml medicine juice 2 times dips medicine juice with aseptic cotton carrier and embrocates the affected part, and oral decoction and pars affecta skin are embrocated medicine juice and are carried out synchronously.7 days is a course for the treatment of.Had a rest 3～5 days, and carried out next course for the treatment of again, use 3 courses for the treatment of.

3. the standard of curative effect evaluation: produce effects: oral and affected part is embrocated 3 courses for the treatment of of decoction, and the large I of pars affecta skin Semen Glycines is touched petechia or ecchymosis, or has the erythra that merges tendency and occur in batches to disappear fully, more recurrence; The clinical symptoms sign complete obiterations such as whole body skin, digestive tract and kidney type; Capillary fragility test, routine urinalysis and Fecal Occult Blood Testing are all normal.

Effectively: oral and affected part is embrocated 3 courses for the treatment of of decoction, and the large I of pars affecta skin Semen Glycines is touched petechia or ecchymosis, or has the erythra that merges tendency and occur in batches substantially to disappear, and recurrence is a small amount of once in a while; The clinical symptoms signs such as whole body skin, digestive tract and kidney type disappear substantially; Slight abnormality appears in capillary fragility test, routine urinalysis and Fecal Occult Blood Testing once in a while.

Invalid: oral and affected part is embrocated 3 courses for the treatment of of decoction, and pars affecta skin, clinical symptoms sign and test, chemical examination etc. are all without changing.

4. therapeutic effect: use the present invention to treat 64 examples, use the standard of curative effect evaluation and carry out treatment effectiveness evaluation: produce effects 39 examples, effective 19 examples, invalid 7 examples, total effective rate 90.1%.

Claims (1)

1. purple silver-colored red cypress soup that is used for anaphylactoid purpura, it is characterized in that: each crude drug composition is by weight percentage, Radix Arnebiae (Radix Lithospermi) 5～8%, Flos Lonicerae 8～11%, Radix Paeoniae Rubra 7～9%, Cacumen Platycladi 5～7%, Cortex Moutan 5～7%, Radix Rehmanniae 4～6%, Herba Schizonepetae 4～6%, Radix Saposhnikoviae 3～6%, Radix Scrophulariae 3～6%, Radix Ophiopogonis 5～7%, Radix Rubiae 3～5%, Rhizoma Imperatae 8～11%, Radix Salviae Miltiorrhizae 4～7%, Radix Glycyrrhizae 2～4%, Radix Notoginseng powder 2～4%, Radix Cynanchi Paniculati 6～9%, Radix Sophorae Flavescentis 4～7%, at first with Radix Notoginseng powder list bag, the 16 flavor crude drug of Yuing are soaked in water, decoct, remove slag to such an extent that add again Radix Notoginseng powder after the filtrate, namely make purple silver-colored red cypress soup.