A kind of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) production technology
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) production technology.
Background technology
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is meant that Rhizoma Pinelliae boils the dry process of preparing Chinese medicine processed goods that forms dry altogether with fresh ginger or fresh ginger, Alumen.
According to version in 2010 " record of Chinese pharmacopoeia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) property is hot, warm, returns spleen, stomach, lung meridian, the function warming middle-JIAO reduces phlegm, stopping nausea and vomiting by lowering the adverse flow of QI is used for vomiting due to fluid-retention, the gastral cavilty feeling of fullness.Its method for making is: get the clean Rhizoma Pinelliae, size separately when being soaked in water to the interior no dried heart, is taken out; Other gets Rhizoma Zingiberis Recens section and fries in shallow oil soup, and it is well-done altogether to add Alumen and the Rhizoma Pinelliae, and taking-up is dried or dried in the air to half-dried drying; Or shave, drying.The clean Rhizoma Pinelliae of every 100kg is with Rhizoma Zingiberis Recens 25kg, Alumen 12.5kg.
Above-mentioned method for making is comparatively general; Poor operability in actual production process, product quality are difficult to control, and the effective ingredient of the Rhizoma Pinelliae runs off easily in immersion process; The effect of Rhizoma Pinelliae absorption Rhizoma Zingiberis Recens and Alumen is also relatively poor, has all reduced the drug effect of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) product to some extent.
Summary of the invention
The object of the present invention is to provide the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) production technology of a kind of easy operating and suitability for industrialized production, constant product quality, good drug efficacy.
To achieve these goals, the technical scheme of the present invention's employing is:
A kind of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) production technology may further comprise the steps:
Step 1, water logging bubble: the Rhizoma Pinelliae was soaked in water 72 hours, and in the immersion process, the water surface will soak more than the Rhizoma Pinelliae 30cm, whenever changed primary water at a distance from 8 hours, disposed Rhizoma Pinelliae surface impurity and attachment when changing water;
Step 2, Alumen soak: the Rhizoma Pinelliae behind the water logging bubble was soaked 48 hours with white alum solution; In the immersion process; Liquid level will soak the Rhizoma Pinelliae, whenever changed white alum solution one time at a distance from 24 hours, and said white alum solution is that Alumen is dissolved in the solution that forms in the water; The consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4.25kg Alumen, and the consumption of water is that every 4.25kg Alumen uses 2500kg water;
Step 3, spice: with the Rhizoma Pinelliae control solid carbon dioxide branch after the Alumen immersion; Adding Alumen and Rhizoma Zingiberis Recens stirs; Said Rhizoma Zingiberis Recens is crossed the wide mesh of 1cm after being ground into pasty state screen cloth obtains; The consumption of Rhizoma Zingiberis Recens is that every 100kg Rhizoma Pinelliae dry product uses the 25kg Rhizoma Zingiberis Recens, and the consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4kg Alumen;
Step 4, steaming and decocting: the Rhizoma Pinelliae that stirs is placed in the boiling case and closes, hides boiling case tight; When then burning in boiler to vapour pressure being 0.3MPa in boiling case air feed (feeding water vapour); When boiling case began to excessive gas, boiler pressure should be stabilized in 0.3MPa, continued to the boiling case air feed; Service life is 4 ~ 6 hours, and air feed is intact to utilize the waste heat in the boiling case to continue to take out after vexed 12 hours;
Step 5, drying: with Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) air drying and stoving to the moisture of taking out is below 13%.
The present invention compared with prior art has following characteristics and advantage:
(1) after step 1 is handled; The Rhizoma Pinelliae does not have the dried heart basically; Soft surface is not compared to there being the dried heart fully with existing being soaked in water, and used soak time shortens greatly; Thereby avoided a large amount of losses of the Rhizoma Pinelliae, kept the drug effect of the Rhizoma Pinelliae better because of the effective ingredient that is immersed in the water for a long time to be caused;
(2) after step 2 was handled, the Rhizoma Pinelliae further was dipped to the interior no dried heart, thereby reaches process of preparing Chinese medicine requirement, to carry out follow-up processing.And find that after deliberation use white alum solution to soak than being soaked in water, the loss of effective ingredient obviously reduces in the Rhizoma Pinelliae; Its reason is still not clear; Possibly be because Alumen is inhibited to the loss of effective ingredient in the Rhizoma Pinelliae, or be the concentration difference principle, and the speed that the effective ingredient of the Rhizoma Pinelliae is run off in white alum solution slows down; Thereby number of dropouts is reduced, and also possibly be the combined effect or the other reasons of above-mentioned two kinds of factors.In a word, adopt white alum solution to soak and both can make the Rhizoma Pinelliae reach the requirement of the interior no dried heart, can reduce the loss of effective ingredient in the Rhizoma Pinelliae again, thereby keep the drug effect of the Rhizoma Pinelliae better.In addition; In traditional method for making, Alumen is when steaming and decocting, to boil disposable the mixing altogether with the Rhizoma Pinelliae, and the Alumen content in the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) product that obtains often exceeds standard (according to the regulation of " Pharmacopoeia of People's Republic of China 2010 editions " easily; Every 100kg Rhizoma Pinelliae; Use Alumen 12.5kg, and the Alumen content in the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) must not surpass 8.5% in aqueous sulfuric acid aluminum potassium); And adopt production technology of the present invention; Alumen is divided into three priorities and adds the Rhizoma Pinelliae; The twice Alumen immersion that is this step spends 8.5kg Alumen (with every 100kg Rhizoma Pinelliae, calculating with Alumen 12.5kg), and the 4kg Alumen of surplus then mixes altogether with the Rhizoma Pinelliae to boil when steaming and decocting again (sees step 4 of the present invention and step 5); And when Alumen soaks; Alumen is to add in the Rhizoma Pinelliae after being diluted to solution again, and the Alumen content in the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) product that therefore obtains can effectively be controlled in the critical field, has improved the qualification rate of product.Also need to prove; If soak Rhizoma Pinelliae dry product no dried heart in the Rhizoma Pinelliae with white alum solution at the very start; Then not only soak effect bad (having prolonged soak time etc. greatly); And soak required Alumen amount and will increase greatly, be used for the Alumen quantity not sufficient of steaming and decocting accordingly, can reduce the drug effect of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) product on the contrary.
(3) in step 3, Rhizoma Zingiberis Recens is that the screen cloth of after being ground into pasty state, crossing the wide mesh of 1cm obtains, and becomes Rhizoma Zingiberis Recens and Alumen, the Rhizoma Pinelliae mix homogeneously of pasty state then.Soup is fried in shallow oil in its Rhizoma Zingiberis Recens section that is different from the existing method for making; Get decoction and Alumen, the blended way of the Rhizoma Pinelliae; The effective ingredient that can better keep Rhizoma Zingiberis Recens; Make Rhizoma Zingiberis Recens better to the detoxifying effect of the Rhizoma Pinelliae, the Rhizoma Zingiberis Recens that stirs into pasty state also is easy to mix homogeneously and composition is easy to absorbed by the Rhizoma Pinelliae, helps improving the drug effect of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) product.
(4) in step 4, the present invention is different from existing method for making, and the waste heat that after steaming and decocting, also makes full use of in the boiling case continued vexed 12 hours, and steaming and decocting gets more and passes through, and the product quality that obtains is better.Can know through above-mentioned analysis, adopt Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) production technology of the present invention, not only easy operating and suitability for industrialized production, and constant product quality, good drug efficacy.In addition, the production cycle of the present invention only needs about 7 ~ 10 days, and the production cycle of existing method for making is generally all longer, have in addition take 3 months, therefore production technology of the present invention can be brought better economic benefit, has market application foreground widely.
Further, in step 1, the preferred spring water that meets drinking water standard that adopts soaks, and the water surface is good to soak Rhizoma Pinelliae 30cm, so that reach best immersion effect water saving the time.
Further, in step 2, preferably Alumen is dissolved in the spring water that meets drinking water standard and forms white alum solution.
Further, in step 4, to drain waste gas and waste water in the steam line before the air feed earlier.
Further, said step 5 is realized by following mode:
Step 51, preliminarily dried: the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) that takes out dried use oven for drying after 10 hours, bake out temperature is 70 ~ 80 ℃, and drying time is 4 ~ 6 hours;
In this step, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is after drying 10 hours, and epidermis dries basically, and is tack-free, and water content is about 40%; Said baking oven can be selected CT-CI type heated-air circulation oven for use; Evenly spread the thick Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of 2cm on each material carrier; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) water content after the oven dry is about 13%; Basically, (regulation in " Pharmacopoeia of People's Republic of China 2010 editions ", the moisture in the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) must not surpass 13%) meets the requirements.
Step 52, sterilizing-drying: through microwave drying sterilization line dry sterilization, temperature is 100 ~ 120 ℃ with the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) behind the preliminarily dried, and linear speed is 90 ~ 110BH.
Through behind the after drying of this step, the moisture in the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is lower than 13%, meets the requirements fully; Sterilization treatment has then improved Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) safety of products performance.
Further, before step 1, also comprise sorting step: the Rhizoma Pinelliae is carried out sorting according to large, medium and small three kinds of specifications, and wherein, diameter is greater than being divided into of 1.5cm of big specification, and diameter is being divided into of 0.8 ~ 1.5cm of a middle specification, and diameter is less than the small dimension that is divided into of 0.8cm.
Further, in step 5, the service life of the big specification Rhizoma Pinelliae is 6 hours, and the service life of the middle specification Rhizoma Pinelliae is 5 hours, and the service life of the small dimension Rhizoma Pinelliae is 4 hours.
The specific embodiment
Embodiment 1
(1) sorting: the Rhizoma Pinelliae is carried out sorting according to large, medium and small three kinds of specifications through screening machine; Wherein, diameter is greater than being divided into of 1.5cm of big specification, and diameter is being divided into of 0.8 ~ 1.5cm of a middle specification; Diameter selects the big specification Rhizoma Pinelliae to carry out following process less than the small dimension that is divided into of 0.8cm;
(2) water logging bubble: the big specification Rhizoma Pinelliae is put into fermentation vat, soaked 72 hours with the spring water that meets drinking water standard, in the immersion process, the water surface soaked Rhizoma Pinelliae 30cm, whenever changed primary water at a distance from 8 hours, disposed Rhizoma Pinelliae surface impurity and attachment when changing water;
(3) Alumen soaks: the Rhizoma Pinelliae behind the water logging bubble was soaked 48 hours with white alum solution at twice totally; In the immersion process; Liquid level soaked the Rhizoma Pinelliae, whenever changed white alum solution one time at a distance from 24 hours, and said white alum solution is that Alumen is dissolved in the solution that forms in the water that meets drinking water standard; The consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4.25kg Alumen, and the consumption of water is that every 4.25kg Alumen uses the 2500kg drinking water;
(4) spice: with the Rhizoma Pinelliae control solid carbon dioxide branch after the Alumen immersion; Put into agitator disk; About every dish 30kg, the Rhizoma Zingiberis Recens that adds Alumen again and be ground into pasty state stirs more than 10 minutes until stirring, and said Rhizoma Zingiberis Recens obtains for the screen cloth of after pulverizer is ground into pasty state, crossing the wide mesh of 1cm; The consumption of Rhizoma Zingiberis Recens is that every 100kg Rhizoma Pinelliae dry product uses the 25kg Rhizoma Zingiberis Recens, and the consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4kg Alumen;
(5) steaming and decocting: the Rhizoma Pinelliae that stirs is placed in the boiling case and closes, hides boiling case tight; When then burning in boiler to vapour pressure being 0.3MPa in boiling case air feed, to drain waste gas and waste water in the steam line before the air feed earlier, when boiling case begins to excessive gas; Boiler pressure should be stabilized in 0.3MPa; Continuation is to the boiling case air feed, and service life is 6 hours, and air feed is intact to utilize the waste heat in the boiling case to continue to take out after vexed 12 hours;
(6) preliminarily dried: the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) that takes out dried put into CT-CI type heated-air circulation oven after 10 hours, the even thick Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of shop 2cm on each material carrier, temperature is adjusted to 70 ~ 80 ℃, continues oven dry 4 ~ 6 hours;
(7) sterilizing-drying: through microwave drying sterilization line dry sterilization, temperature measurer is shown as 100 ~ 120 ℃ with the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) behind the preliminarily dried, and speed governing is shown as 90 ~ 110BH.
Embodiment 2
(1) sorting: the Rhizoma Pinelliae is carried out sorting according to large, medium and small three kinds of specifications through screening machine; Wherein, diameter is greater than being divided into of 1.5cm of big specification, and diameter is being divided into of 0.8 ~ 1.5cm of a middle specification; Diameter is less than the small dimension that is divided into of 0.8cm, and the specification Rhizoma Pinelliae carries out following process in the selection;
(2) water logging bubble: the middle specification Rhizoma Pinelliae is put into fermentation vat, soaked 72 hours with the spring water that meets drinking water standard, in the immersion process, the water surface soaked Rhizoma Pinelliae 30cm, whenever changed primary water at a distance from 8 hours, disposed Rhizoma Pinelliae surface impurity and attachment when changing water;
(3) Alumen soaks: the Rhizoma Pinelliae behind the water logging bubble was soaked 48 hours with white alum solution at twice totally; In the immersion process; Liquid level soaked the Rhizoma Pinelliae, whenever changed white alum solution one time at a distance from 24 hours, and said white alum solution is that Alumen is dissolved in the solution that forms in the water that meets drinking water standard; The consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4.25kg Alumen, and the consumption of water is that every 4.25kg Alumen uses the 2500kg drinking water;
(4) spice: with the Rhizoma Pinelliae control solid carbon dioxide branch after the Alumen immersion; Put into agitator disk; About every dish 30kg, the Rhizoma Zingiberis Recens that adds Alumen again and be ground into pasty state stirs more than 10 minutes until stirring, and said Rhizoma Zingiberis Recens obtains for the screen cloth of after pulverizer is ground into pasty state, crossing the wide mesh of 1cm; The consumption of Rhizoma Zingiberis Recens is that every 100kg Rhizoma Pinelliae dry product uses the 25kg Rhizoma Zingiberis Recens, and the consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4kg Alumen;
(5) steaming and decocting: the Rhizoma Pinelliae that stirs is placed in the boiling case and closes, hides boiling case tight; When then burning in boiler to vapour pressure being 0.3MPa in boiling case air feed, to drain waste gas and waste water in the steam line before the air feed earlier, when boiling case begins to excessive gas; Boiler pressure should be stabilized in 0.3MPa; Continuation is to the boiling case air feed, and service life is 5 hours, and air feed is intact to utilize the waste heat in the boiling case to continue to take out after vexed 12 hours;
(6) preliminarily dried: the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) that takes out dried put into CT-CI type heated-air circulation oven after 10 hours, the even thick Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of shop 2cm on each material carrier, temperature is adjusted to 70 ~ 80 ℃, continues oven dry 4 ~ 6 hours;
(7) sterilizing-drying: through microwave drying sterilization line dry sterilization, temperature measurer is shown as 100 ~ 120 ℃ with the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) behind the preliminarily dried, and speed governing is shown as 90 ~ 110BH.
Embodiment 3
(1) sorting: the Rhizoma Pinelliae is carried out sorting according to large, medium and small three kinds of specifications through screening machine; Wherein, diameter is greater than being divided into of 1.5cm of big specification, and diameter is being divided into of 0.8 ~ 1.5cm of a middle specification; Diameter selects the small dimension Rhizoma Pinelliae to carry out following process less than the small dimension that is divided into of 0.8cm;
(2) water logging bubble: the small dimension Rhizoma Pinelliae is put into fermentation vat, soaked 72 hours with the spring water that meets drinking water standard, in the immersion process, the water surface soaked Rhizoma Pinelliae 30cm, whenever changed primary water at a distance from 8 hours, disposed Rhizoma Pinelliae surface impurity and attachment when changing water;
(3) Alumen soaks: the Rhizoma Pinelliae behind the water logging bubble was soaked 48 hours with white alum solution at twice totally; In the immersion process; Liquid level soaked the Rhizoma Pinelliae, whenever changed white alum solution one time at a distance from 24 hours, and said white alum solution is that Alumen is dissolved in the solution that forms in the water that meets drinking water standard; The consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4.25kg Alumen, and the consumption of water is that every 4.25kg Alumen uses the 2500kg drinking water;
(4) spice: with the Rhizoma Pinelliae control solid carbon dioxide branch after the Alumen immersion; Put into agitator disk; About every dish 30kg, the Rhizoma Zingiberis Recens that adds Alumen again and be ground into pasty state stirs more than 10 minutes until stirring, and said Rhizoma Zingiberis Recens obtains for the screen cloth of after pulverizer is ground into pasty state, crossing the wide mesh of 1cm; The consumption of Rhizoma Zingiberis Recens is that every 100kg Rhizoma Pinelliae dry product uses the 25kg Rhizoma Zingiberis Recens, and the consumption of Alumen is that every 100kg Rhizoma Pinelliae dry product uses the 4kg Alumen;
(5) steaming and decocting: the Rhizoma Pinelliae that stirs is placed in the boiling case and closes, hides boiling case tight; When then burning in boiler to vapour pressure being 0.3MPa in boiling case air feed, to drain waste gas and waste water in the steam line before the air feed earlier, when boiling case begins to excessive gas; Boiler pressure should be stabilized in 0.3MPa; Continuation is to the boiling case air feed, and service life is 4 hours, and air feed is intact to utilize the waste heat in the boiling case to continue to take out after vexed 12 hours;
(6) preliminarily dried: the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) that takes out dried put into CT-CI type heated-air circulation oven after 10 hours, the even thick Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of shop 2cm on each material carrier, temperature is adjusted to 70 ~ 80 ℃, continues oven dry 4 ~ 6 hours;
(7) sterilizing-drying: through microwave drying sterilization line dry sterilization, temperature measurer is shown as 100 ~ 120 ℃ with the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) behind the preliminarily dried, and speed governing is shown as 90 ~ 110BH.
The above is merely embodiments of the invention; Be not so limit claim of the present invention; Every equivalent structure or equivalent flow process conversion that utilizes description of the present invention to do; Or directly or indirectly be used in other relevant technical fields, all in like manner be included in the scope of patent protection of the present invention.