CN102755468A - 一种降低糖尿病眼病的眼压的外用保健品 - Google Patents
一种降低糖尿病眼病的眼压的外用保健品 Download PDFInfo
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- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims abstract description 6
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Abstract
本发明涉及一种降低糖尿病眼病的眼压的外用保健品,其特征在于:含有枸杞多糖2-5毫克、泽泻多糖3-7毫克、西红花总皂苷4-7毫克、人参总皂苷4-7毫克、栀子总皂苷15-45毫克、甘露醇3-7毫克，四丁酚醛15-25毫克，依地酸二钠15-25毫克，氯化钾15-25毫克，氮酮25-25毫克，盐酸2-5毫升或氢氧化钾1-3毫克(调节pH值)，纯水1000-3000毫克，能清肝明目，疏肝泻火、缩瞳止痛、降眼压。
Description
技术领域
本发明涉及保健品领域,具体涉及一种降低糖尿病眼病的眼压的外用保健品。
背景技术
据一项国内眼病流行病学调查显示，糖尿病眼病已成为我国主要眼科疾病，糖尿病的威胁之一是长期血糖控制不良导致的微血管和大血管并发症,可以使患者失明。有40%的2型糖尿病人在确诊时就已经发生了糖尿病型视网膜病变,在糖尿病确诊20年后的所有1型糖尿病和60%的2型糖尿病人会发生不同程度的糖尿病型视网膜病变.目前对于糖尿病型视网膜病变尚没有很好的药物进行治疗,一般都是采用手术的方法进行治疗,但是,在手术之后的恢复往往不理想,其中80%的手术病人会出现眼压急剧升高的现象,病人出现恶心,头晕,呕吐,出血的症状,甚至手术失败,因此,开发降低糖尿病眼病的眼压的保健品,非常有价值。
发明内容
本发明涉及一种降低糖尿病眼病的眼压的外用保健品,其特征在于: 含有枸杞多糖、泽泻多糖、西红花总皂苷、人参总皂苷、甘露醇，四丁酚醛，依地酸二钠，氯化钾，氮酮，适量盐酸或氢氧化钾(调节pH值)和纯水。
本发明涉及一种降低糖尿病眼病的眼压的外用保健品,其特征在于:
含有枸杞多糖2-5毫克、泽泻多糖3-7毫克、西红花总皂苷4-7毫克、人参总皂苷4-7毫克、栀子总皂苷15-45毫克、甘露醇3-7毫克，四丁酚醛15-25毫克，依地酸二钠15-25毫克，氯化钾15-25毫克，氮酮25-25毫克，盐酸2-5毫升或氢氧化钾1-3毫克(用来调节pH值) ，纯水1000-3000毫克。
本发明的制备方法是：取pH调节剂以外的物质，加入纯水，溶解，过滤，加入pH调节剂，调节pH值至7.0。
本发明的核心是，开发一种降低糖尿病眼病的眼压的外用保健品，能够稳定持续降低眼压，将会给糖尿病眼病的临床治疗带来进步，能清肝明目，疏肝泻火、缩瞳止痛、降眼压。
本发明的用法与用量：当作为单独或者协同治疗药物时，其使用剂量是往太阳穴滴入3滴本发明的外用保健品，每天三次。有些患者每天四次时效果更佳。通常推荐在点药后轻轻闭上眼睛,轻揉太阳穴半小时。
本发明的好处，通过外用可以减少眼部直接应用时全身的吸收剂量，从而减少全身副作用。
具体实施例
实施例1
本发明涉及一种降低糖尿病眼病的眼压的外用保健品,其特征在于:
取枸杞多糖2毫克、泽泻多糖3毫克、西红花总皂苷4毫克、人参总皂苷4毫克、栀子总皂苷15毫克、甘露醇3毫克，四丁酚醛15毫克，依地酸二钠15毫克，氯化钾15毫克，氮酮25毫克，加入纯水1000毫克，溶解，过滤，加入盐酸2毫升调节pH值至7.0。
实施例2
取枸杞多糖5毫克、泽泻多糖7毫克、西红花总皂苷7毫克、人参总皂苷7毫克、栀子总皂苷45毫克、甘露醇7毫克，四丁酚醛25毫克，依地酸二钠25毫克，氯化钾25毫克，氮酮25毫克，加入纯水3000毫克，溶解，过滤，加入碳酸氢钾3毫克调pH值至7.0。
实施例3
其使用剂量是往太阳穴滴入3滴本发明实施例2的降低糖尿病眼病的眼压的外用保健品，每天三次，连续10天。
病例选择：反复发作，视力下降的糖尿病眼30名病人，有时眼疼，发作性虹视，瞳孔散大，共有54只眼压超过22mmHg，部分患者视神经萎缩，失明不超过2个月。
处理后10天的54只眼压平均值在（9.2±0.1）到（17.2±0.4），出现明显下降，
34只眼压平均值在（9.2±0.1）到（12.1±0.5），
20只眼压平均值在（12.1±0.5）到（17.2±0.4），
所有患者眼疼消失，虹视消失，瞳孔变小
| 眼压变化 | 年龄 | 糖尿病 | 糖尿病史 | 第1天没有用药的眼压压力 | 处理后4小时的压力 | 处理后10天的压力 | |
| 早饭前血糖数值（mmol/L） | 年 | (mmHg) | (mmHg) | (mmHg) | |||
| 张某 | 左眼 | 56 | 12.3 | 15 | 27.4±0.3 | 17.1±0.8 | 12.1±0.4 |
| 陈某 | 右眼 | 69 | 23.1 | 18 | 44.7±0.7 | 27.3±0.4 | 17.1±0.3 |
| 王某 | 右眼 | 70 | 15.6 | 21 | 23.2±0.7 | 17.1±0.5 | 9.2±0.2 |
| 孙某 | 左眼 | 83 | 17.3 | 8 | 31.9±0.3 | 19.2±0.7 | 8.7±0.3 |
| 李某 | 左眼 | 49 | 8.9 | 14 | 49.3±0.7 | 29.7±0.7 | 12.3±0.4 |
| 艾某 | 右眼 | 78 | 9.5 | 17 | 38.7±0.4 | 27.5±0.9 | 9.7±0.3 |
| 蓝某 | 右眼 | 64 | 11.3 | 20 | 48.2±0.2 | 29.1±0.8 | 14.2±0.5 |
| 尤某 | 左眼 | 71 | 12.3 | 19 | 40.7±-0.8 | 27.1±0.5 | 13.1±0.4 |
Claims (2)
1.本发明涉及一种降低糖尿病眼病的眼压的外用保健品,其特征在于: 含有枸杞多糖2-5毫克、泽泻多糖3-7毫克、西红花总皂苷4-7毫克、人参总皂苷4-7毫克、栀子总皂苷15-45毫克、甘露醇3-7毫克，四丁酚醛15-25毫克，依地酸二钠15-25毫克，氯化钾15-25毫克，氮酮25-25毫克，调节pH的盐酸2-5毫升或氢氧化钾1-3毫克 ，纯水1000-3000毫克。
2.根据权利1的本发明的制备方法是：取pH调节剂以外的物质，加入纯水，溶解，过滤，加入pH调节剂，调节pH值至7.0。
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| CN201210288125.XA CN102755468B (zh) | 2012-03-11 | 2012-08-15 | 一种降低糖尿病眼病的眼压的外用保健品 |
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| CN201210288125.XA Expired - Fee Related CN102755468B (zh) | 2012-03-11 | 2012-08-15 | 一种降低糖尿病眼病的眼压的外用保健品 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102006872A (zh) * | 2008-02-19 | 2011-04-06 | 马韦尔生命科学有限公司 | 含有吡啶酚衍生物的眼科制剂 |
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- 2012-03-11 CN CN2012100614748A patent/CN102526282A/zh not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102006872A (zh) * | 2008-02-19 | 2011-04-06 | 马韦尔生命科学有限公司 | 含有吡啶酚衍生物的眼科制剂 |
Non-Patent Citations (1)
| Title |
|---|
| 王纯庠等: "中医药治疗糖尿病视网膜病变回眸研究", 《中西医结合心脑血管病杂志》 * |
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| CN102526282A (zh) | 2012-07-04 |
| CN102755468B (zh) | 2014-03-05 |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140305 Termination date: 20200815 |