CN102754182B - The electrode system of linear ion hydrazine - Google Patents
The electrode system of linear ion hydrazine Download PDFInfo
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- CN102754182B CN102754182B CN201080063426.1A CN201080063426A CN102754182B CN 102754182 B CN102754182 B CN 102754182B CN 201080063426 A CN201080063426 A CN 201080063426A CN 102754182 B CN102754182 B CN 102754182B
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/422—Two-dimensional RF ion traps
- H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/422—Two-dimensional RF ion traps
- H01J49/423—Two-dimensional RF ion traps with radial ejection
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- Analytical Chemistry (AREA)
- Electron Tubes For Measurement (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electrostatic Separation (AREA)
Abstract
The present invention relates to the field of mass spectral analysis, especially, the formation that the present invention relates to linear ion hydrazine and linear ion hydrazine catches the design of the electrode system of field.The electrode system of linear ion hydrazine required for protection has four electrodes, is relatively placed for every a pair.The plane of symmetry of electrode pair is mutually vertical.Be different from standard type, each electrode of at least one pair of electrode has the cross section of the shape being essentially isosceles triangle.This leg-of-mutton top is towards the longitudinal axis of trap.In angle between two waists of this isosceles triangle is 130 ° to 152 °, obtain optimum.In other words, the angle between the working face of electrode is 130 ° to 152 °.Be less than 24% of the inscribed radius of trap for the gap width of ejected ion in this electrode.The electrode system for linear ion hydrazine advised allows to reach high-resolution, and this resolution has comparativity relative to the resolution of the ion trap with hyperbolic geometry shape, namely significantly higher than the resolution that can be obtained by standard ionomer trap.Simultaneously the working face of electrode is in the proposed system made up of flat surfaces, and these flat surfaces are placed with specific angle each other, and the top of angle is towards ion trap axle.The manufacture of this electrode is simpler.The local attenuation of the angle compensation field intensity in the region of spray slits.
Description
Technical field
The present invention relates to the field of mass spectral analysis, especially, the present invention relates to the design that linear ion hydrazine and formation catch the electrode system of the linear ion hydrazine of field.Ion trap directly can be used to quality analysis, and also can be used to catch ion cloud a period of time and the preparation of ion population for further analyzing in the mass spectrometer of downstream.
Background technology
It is well known in the art for having the linear ion hydrazine formed by four elongated electrode (shaft-like) arranged round common axis (trap axis) of catching field.Beeline-r from axis to electrode surface
0be called as the inscribed radius of " field radius " or trap.This is the main geometric parameters of trap.The main distinction in the design of linear ion hydrazine is the shape of the working face of electrode, namely defines the interior shape of the electrode of field shape in radial directions.The field of catching generated in this trap is by applying radio-frequency potential RF+ and RF-(i.e. RF source hereinafter), positive phase is on a pair electrode staggered relatively, and minus phase is in corresponding another pair of electrodes.The amplitude V in RF source
rFwith the major parameter that frequency omega is also ion trap, because this amplitude and frequency define the mass range of the ion of catching.The magnetic field generated by the AC current potential changed is used to have the operation of ion cloud.Positive potential and negative potential (AC+ and AC-) are applied in a pair electrode staggered relatively.Enter into the resonance of exciting field ion among, ion increase its vibration amplitude and can occur on electrode.In the ion trap with radial spray effect, ion is injected into detector via the slit in electrode, slit be with the axis being parallel of trap be cut.Spray slits can be used in all four electrodes.
The method of the ion manipulation in ion trap is the resonant excitation based on ionic agitation.The basic frequency (characteristic frequency) of Here it is why ionic agitation should be explicitly defined, and only should depend on mass of ion.In order to reach this object, the restoring force of effective current potential of trap linearly should be proportional to the distance of ion to trap axis.Quadrupole field is only had to have this characteristic.In order to generate quadrupole field, the electrode of trap should have hyp shape, because hyperbola is the equipotential surface of quadrupole field.
United States Patent (USP) 6,797,950 describe and have symmetrically around the linear ion hydrazine of four extension electrodes of the longitudinal arrangement of trap, and each electrode has the working face of hyperbolic shape.Manufacture and the accurate assembling of hyperbola electrode are complicated and the process of costliness.Along with the miniaturization of ion trap, these problems become more difficult.Defect (imperfection) is introduced the shape of catching field by the existence of spray slits, causes the reduction at slit adjacent place electric field.Due to this, the ion trap with hyperbola electrode is more suitable for being designed to have narrow slit, is namely no more than 10% of inscribed radius.
At United States Patent (USP) 6,838, the ion trap described in 666 meets requirement that is miniaturized and that manufacture better.The electrode of this trap is the flat board extended.Meanwhile, owing to catching the significant skew of field relative to four poles, this simplification of design causes the remarkable degeneration of catching a shape.It is well known that magnetic field intensity is weakened at flat electrode near surface, therefore the use of plate electrode is just increased in the field decay of spray slits adjacent place.The characteristic frequency of ion becomes and not only depends on mass of ion, also depends on the amplitude of ionic agitation.Increasing the amplitude of ionic agitation and while ion convergence spray slits, ion departs from and the resonance of exciting field.Therefore, ion or not via slot injection to detector, or spray after significant time delay, this can reduce the resolution of quality analysis significantly.
By changing the current potential along the surface of flat electrode, field shape can improve to a certain extent.Patent application WO2005/119737 describes a kind of linear ion hydrazine, and wherein flat electrode is divided into multiple longitudinal fillet.RF current potential is applied in fillet in certain proportion.The advantage of this trap can manufacture electrode by means of printed-board technology.By means of the multiple fillet of each electrode, the shape of catching field can more close to four poles.Meanwhile, this solution of problem causes the complicated significantly of power supply.
International patent application WO 2007/025475 describes multiple design for mass spectrometric lineation electrode with different shape of working surfaces.The shape that those designs have a common characteristic-working face has two or more steps.A part for described design, especially has those electrodes in arc-shaped step face, has the advantages and problems identical with the electrode of above-mentioned hyperbolic surface.Mentioned patent application also describes the electrode with smooth land plateau.This electrode can four extremely near form magnetic field, and the manufacture of this electrode is more simply too much than the manufacture of hyperbola electrode.Especially, those electrodes shown in Fig. 1 of application WO2007/025475 specification are selected as standard.But, even those electrodes, neither be immaculate.Spray slits is positioned at the upper planar step of this electrode.The reduction of the resolution of quality analysis is caused in the existence of slit areas midplane.
Summary of the invention
Problem to be solved by this invention simplifies electrode design while of improving mass spectrometer resolution.Technological achievement is the compensation of the field decay near spray slits.Target is achieved by the amendment of electrode design.
The electrode system of the linear ion hydrazine proposed has four electrodes, is relatively placed for every a pair.The plane of symmetry of electrode pair is mutually vertical.Be different from standard type, the cross section with the shape being essentially isosceles triangle of each electrode of at least one pair of electrode.This leg-of-mutton top is towards the longitudinal axis of trap.In angle between two waists of this isosceles triangle is 130 ° to 152 °, obtain optimum.Angle between the working face of in other words electrode is 130 ° to 152 °.Be less than 24% of the inscribed radius of trap for the gap width of ejected ion in this electrode.
Accompanying drawing explanation
Further explain the efficiency of electrode shape proposed, and enumerate the example (for the sake of simplicity, be three corner electrodes hereinafter referred to as this electrode) of the instrument of the ion trap of the electrode with isosceles triangle shape cross section.Below will illustrate the present invention by figure:
Fig. 1 is the three-dimensional projection of ion trap electrodes system.
Fig. 2 is the schematic cross section of the ion trap with identical electrodes.
Fig. 3 is, in the ion trap with three corner electrodes, the ionic agitation intensity in X-direction (excitation direction) is as the function of time t, and the figure at several value places of angle α between leg-of-mutton waist, wherein α=140 ° in A figure, α=142 ° in B figure, in C figure during α=134 °.
Fig. 4 is in angle [alpha]=140 ° of three corner electrodes, and excitation pulse amplitude is when multiple different numerical value, and the quality of spraying from ion trap in each unit interval is the chart of the number (function for time t) of the ion of 1891Da, wherein U in a figure
aC=0.4V(resolution 4571), U in b figure
aC=0.5V(resolution 6603), U in c figure
aC=0.6V(resolution 2971).
Fig. 5 be have inscribed radius numerical value be the trap of 5mm under multiple different gap width, the situation that resolution changes with angle [alpha].
Fig. 6 is in the acquisition optimum angle alpha at ultimate resolution place and the relation of spray slits width.
Fig. 7 is the schematic diagram of the viewgraph of cross-section of the ion trap with two three corner electrodes and two flat electrodes.
Embodiment
Author of the present invention has realized that when using ion trap as mass spectrometer, working face can be used to comprise the linear ion trap electrodes of flat, keep high-resolution simultaneously.The flat of electrode is adjacent one another are, is built into the prism of the cross section with isosceles triangle shape.For having the electrode system of four this electrodes shown in Fig. 1.In order in a longitudinal direction, (along trap axis) catches ion, can use the segmentation of film from trap both sides or electrode as (do not have show in the drawings) in standard type.
The system proposed comprises two pairs of electrodes 1.In every pair of electrodes, electrode is positioned on relative position.The plane of symmetry of electrode pair is vertical each other.Each cross section had in two electrodes of at least one pair of electrode has the shape of top towards the isosceles triangle of the longitudinal axis of trap substantially.Parameter r in Fig. 1
0be the inscribe radius of a circle between electrode, α is the angle between the working face 2 of electrode 1.As shown in fig. 1, leg-of-mutton base angle can be cut, and the remainder of working face is made into smooth.In literary composition of the present invention, " isosceles triangle " shape in electrode cross section is appreciated that the shape of the exterior contour that cross section is main.At this contoured interior, namely in the inside of the electrode at working face 2 back side, groove 3 can present with arbitrary shape.In proposed ion trap designs, each of two electrodes that a centering is relative has longitudinal slit (appointment d is gap width), and for detector ejected ion, slit is positioned at leg-of-mutton top, namely in the electrode plane of symmetry.Above-mentioned excitation potential AC+ and AC-is applied between those electrodes.
Topmost parameter as mass spectrometric ion trap is resolution, and this resolution equals the ratio of mass of ion to the peak width of the ionic current represented by mass unit.In order to the proposed ion trap definition resolution with three corner electrodes, carry out the simulation of the quality choice resonance injection of ion.
The ion trap with electrode shown in Fig. 2, wherein uses inscribed radius r
0=5mm and gap width d=0.8mm modeling.Periodically catching RF source is that to have duty ratio be 0.5 and amplitude V
rFthe bipolarity square-wave signal of=500V.By increasing the signal period step by step, this shape in RF source is the shape realizing frequency scanning most convenient.In simulations, square-wave cycle increases 50ps after often completing 20 RF circulations.
Modeling is carried out to the single charged ion of quality 1891Da.In order to add up better, cluster ion comprises 1000 identical particles.According to having the routine distribution that standard deviation is 0.05mm in the radial direction X and Y two to the random distribution of ion initial alignment, corresponding to asymmetric ion cloud in the heart in trap.The initial period in square wave RF source is chosen as close to 2.5 μ s, so as ion resonance spray approximately occur in 20-30ms after.In order to the ion collision modeling with buffer gas, use rigid ball collision model.Pressure is that the helium under 0.2mTorr is used as buffer gas.Modeling supposition field does not change with the axial location along trap.This supposition is at least effective for the core of trap.
In order to the injection of ion, between the comparative electrode of trap, apply the little excitation signal added.In modeling, this exciting voltage (AC) is applied between the electrode in X-direction, as shown in Figure 2.Additional excitation is implemented as has the pulse that pulse duration equals the positive pole in the cycle in 1.5 times of main RF sources, and repetition rate is every 3 RF circulation.This exciting causes, when the characteristic frequency of ion catches 1/3 of source frequency close to master, producing resonate with ionic agitation.As the result progressively increasing the RF cycle, the characteristic frequency of ion increases, and produces resonate with additional excitation.The amplitude of ionic agitation becomes large and arrives the electrode of trap, and ion penetration slit walks abreast to detector.In modeling, to the Ion Counting (being generally 20 μ s) and arriving detector in Fixed Time Interval, and draw the histogram of ionic current.This histogram reflects the peak shape from the ion with equal in quality.
For having the linear ion hydrazine that spray slits width is 0.8mm, can find that the optimum electrode angle that ion sprays is 140 °.Fig. 3 A show for have 140 ° of electrode angles ion trap along the time domain exciting (X) direction ionic agitation amplitude.Large about 20ms, ion is absorbed among the resonance with exciting field, and the amplitude of ionic agitation starts to increase.Oscillation intensity is even increase, and after another 1.5ms, ion is injected along X-axis positive direction via slit, because the coordinate of ion becomes larger than the inscribed radius (5mm) of trap.Although due to random initial condition and the collision random with buffer gas molecules, ion will arrive detector in the different time, if oscillation intensity increases as shown in fig. 3, the span of the injecting time of Approximation Quality ion will be little.Therefore for this situation, high-resolution can be expected.
When electrode angle α is greater than optimum angle slightly, the increase of oscillation intensity as shown in Figure 3 B.Amplitude slowly increases and remains on for a long time in the level of 4mm in this case, and namely ion stands long vibration in slit adjacent place.When entering in slit areas under the RF phase place that some is good, although ion penetration slit arrives detector, the time of spraying is unpredicted.Therefore the time span of ion injecting time shows as very large, and resolution is less.In other cases, when electrode angle α is less than optimum angle (Fig. 3 C), the initial growth of oscillation intensity is interrupted at about 4mm place, and ion from the resonance of exciting field depart from.Amplitude sharply reduces, and ion enters among the resonance with exciting field again.Repeatedly, and the motion of ion has beat frequency as shown in Figure 3 C to this process.The ion simultaneously vibrated never arrives spray slits and does not occur on the detector.Can be ensured the injection of ion in this case by the increase of excitation amplitudes, but this also causes the reduction of the large and resolution of the change of injecting time span compared with optimal cases.
In order to define the resolution of trap, must simulate a large amount of ion, and find the time of injection for each ion.By the result of this simulation, the histogram of the number of ions sprayed under may be plotted in different time, this will provide peak shape, therefrom can obtain resolution.For having this histogrammic example of the ion trap of 140 ° of electrode angles shown in Fig. 4.Curve " a ", " b ", " c " is corresponding to different excitation pulse amplitude (U in a
ex=0.4V(resolution 4571); U in b
ex=0.5V(resolution 6603); U in c
ex=0.6V(resolution 2971)).Best peak shape is in " b " situation.0.18ms in the peak width at maximum half place.This width can represent by mass unit, is considered as sweep speed.Therefore, when current modeling scan speed is 1591Da/s, peak width corresponds to Δ M=0.1810
-3* 1591=0.29Da.Resolution is defined as the ratio R=M/ Δ M of mass of ion and peak width, and equals 1891/0.29=6603.
In multiple different gap width situation, for the ion trap with three corner electrodes of comparative electrode angle, make the similar modeling with the identification of excitation pulse best amplitude and the definition of ultimate resolution.Result as shown in Figure 5.
Ultimate resolution 6600 is 16% of 0.8mm(or inscribed radius in gap width), obtain when electrode angle is 140 °.It is worth mentioning that this resolution under condition of similarity only to obtain in the ion trap with hyperbolic electrode.The chart of the resolution of comparative electrode angle be presented at high angle (being greater than 140 °) resolution sharply be reduced to hundreds of, simultaneously smaller angle resolution be gradually be reduced to 2000, now electrode angle is 130 °.Although resolution 2000 is not high especially, but still it is the twice with the ultimate resolution that can obtain in the ion trap of flat electrode.Therefore from the angular range of 140 ° to 130 ° be with practical value.At the comparatively small gap width (or 8% of inscribed radius) that gap width is 0.4mm, best angle is to high value 148 ° transfer.Ultimate resolution is varied down to 6000 slightly, although remain high level.In other side, the change of this curve is similar to curve when gap width is 0.8mm.Gap width is 24% of 1.2mm(or inscribed radius) time ultimate resolution be only 2000, and best angle is 130 °.
To the ion trap of three corner electrodes with zero gap width, namely without the ion trap of slit, set up similar modeling.In this case, ion cannot be injected into detector, and disappears on electrode.Although this trap cannot be used as mass spectrometer, this device can be used for as the analysis by means of the downstream mass spectrometric further stage prepares ion cloud.By resonant excitation, unwanted ion on electrode can be removed, and the ion of desirable quality is stayed in ion trap capacity.Therefore the measurement without the ion trap intermediate-resolution of slit not only only has theory value.According to curve in Figure 5, best angle is 152 ° in this case, and ultimate resolution is more than 4000.
The result of definition best angle is summarized in Fig. 6.Solid-line curve in this figure corresponds to the angle value obtaining ultimate resolution place under corresponding gap width.Shadow region corresponds to the angular range that resolution is not less than 80% place of maximum.Can draw from chart, depend on gap width from the angular regions of 130 ° to 152 °, be with practical value for the ion trap with three corner electrodes.
According to as mentioned above, the structure of the electric field that the resolution of trap is generated by trap electrode defines.Afterwards when the size of trap proportional reduce or increase time, do not change this definition.Even if Here it is why for having the ion trap modeling of 5mm inscribed radius, if use the ion trap of different inscribed radius, the quality of ion trap operation can not reduce, and advise that other all sizes changes pro rata.Why Here it is can determine that, if gap width is equal with the corresponding part of inscribed radius, the angular regions shown in Fig. 6 will be identical for the ion trap with geometry described in the present invention.Therefore gap width is that the upper bound of 1.2mm is corresponding to 24% of inscribed radius in figure 6.
What Fig. 7 showed is have the viewgraph of cross-section of three corner electrodes in X-direction at the core of the trap with simple flat electrode in the Y-axis direction.The optimum electrode angle of this trap can be defined by method described above.Therefore this geometry becomes a member of trap " series " described in the invention.
Propose from the above as follows, electrode system for linear ion hydrazine allows to obtain high-resolution, this resolution has comparativity relative to the resolution of the ion trap with hyperbolic geometry shape, namely significantly higher than the resolution that can be obtained by standard ionomer trap.Simultaneously the working face of electrode is in the proposed system made up of plane, and these planes are placed with specific angle each other, and the top of angle is towards ion trap axle.The manufacture of this electrode is simply many.The local attenuation of the angle compensation field intensity in the region of spray slits.
Claims (2)
1. the electrode system of a linear ion hydrazine, it is characterized in that, described electrode system has by four electrodes staggered relatively in couples, the plane of symmetry of electrode pair is mutually orthogonal, the each described electrode of electrode described at least one pair of has the cross section being essentially isosceles triangle shape, the top of described isosceles triangle is towards the longitudinal axis of described trap, described each electrode has the slit for ejected ion, described slit is positioned at the plane of electrode symmetry, and the width of described slit is less than or equal to 24% of the inscribed radius of described trap and is more than or equal to 8% of the described inscribed radius of described trap.
2. electrode system as claimed in claim 1, it is characterized in that, the angle between described leg-of-mutton limit is within the scope of 130 ° to 152 °.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010104792/07A RU2466475C2 (en) | 2010-02-11 | 2010-02-11 | Electrode system of linear ion trap |
| RU2010104792 | 2010-02-11 | ||
| PCT/RU2010/000494 WO2011099889A1 (en) | 2010-02-11 | 2010-09-06 | Electrode system of a linear ion trap |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102754182A CN102754182A (en) | 2012-10-24 |
| CN102754182B true CN102754182B (en) | 2015-08-26 |
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| CN201080063426.1A Active CN102754182B (en) | 2010-02-11 | 2010-09-06 | The electrode system of linear ion hydrazine |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2534670B1 (en) |
| CN (1) | CN102754182B (en) |
| RU (1) | RU2466475C2 (en) |
| WO (1) | WO2011099889A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103714878B (en) * | 2014-01-15 | 2016-06-08 | 中国科学院武汉物理与数学研究所 | A kind of integrated ion imprison device |
| CN103903954B (en) * | 2014-03-13 | 2016-03-30 | 复旦大学 | A kind of linear ion hydrazine |
| CN103928288B (en) * | 2014-04-17 | 2017-01-04 | 复旦大学 | A kind of triangle circular ring ion trap for ion storage Yu quality analysis |
| CN107104032B (en) * | 2017-06-07 | 2019-04-23 | 苏州大学 | Linear ion hydrazine, mass spectrograph and method based on asymmetric triangular-shaped electrodes |
| GB201907139D0 (en) * | 2019-05-21 | 2019-07-03 | Thermo Fisher Scient Bremen Gmbh | Improved electrode arrangement |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1137046A2 (en) * | 2000-03-13 | 2001-09-26 | Agilent Technologies Inc. a Delaware Corporation | Manufacturing precision multipole guides and filters |
| CA2648879A1 (en) * | 2006-05-19 | 2008-07-31 | Thermo Finnigan Llc | System and method for implementing balanced rf fields in an ion trap device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IT528250A (en) * | 1953-12-24 | |||
| US6797950B2 (en) | 2002-02-04 | 2004-09-28 | Thermo Finnegan Llc | Two-dimensional quadrupole ion trap operated as a mass spectrometer |
| US6723986B2 (en) * | 2002-03-15 | 2004-04-20 | Agilent Technologies, Inc. | Apparatus for manipulation of ions and methods of making apparatus |
| US6838666B2 (en) | 2003-01-10 | 2005-01-04 | Purdue Research Foundation | Rectilinear ion trap and mass analyzer system and method |
| US7034293B2 (en) * | 2004-05-26 | 2006-04-25 | Varian, Inc. | Linear ion trap apparatus and method utilizing an asymmetrical trapping field |
| CN1326191C (en) * | 2004-06-04 | 2007-07-11 | 复旦大学 | Ion trap quality analyzer constructed with printed circuit board |
| EP1930937A4 (en) * | 2005-08-30 | 2010-10-06 | Fang Xiang | Ion trap, multiple-electrode-pole system and electrode pole for mass spectrometic analysis |
| RU2368980C1 (en) * | 2005-08-30 | 2009-09-27 | Сян ФАН | Ion trap, multipolar electrode system and electrode for mass-spectrometric analysis |
| CN1925102A (en) * | 2005-08-30 | 2007-03-07 | 方向 | Optimized field linear ion trap and its mass analyzer |
| US7351965B2 (en) * | 2006-01-30 | 2008-04-01 | Varian, Inc. | Rotating excitation field in linear ion processing apparatus |
| GB0703378D0 (en) * | 2007-02-21 | 2007-03-28 | Micromass Ltd | Mass spectrometer |
-
2010
- 2010-02-11 RU RU2010104792/07A patent/RU2466475C2/en not_active IP Right Cessation
- 2010-09-06 WO PCT/RU2010/000494 patent/WO2011099889A1/en active Application Filing
- 2010-09-06 EP EP10787587.4A patent/EP2534670B1/en active Active
- 2010-09-06 CN CN201080063426.1A patent/CN102754182B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1137046A2 (en) * | 2000-03-13 | 2001-09-26 | Agilent Technologies Inc. a Delaware Corporation | Manufacturing precision multipole guides and filters |
| CA2648879A1 (en) * | 2006-05-19 | 2008-07-31 | Thermo Finnigan Llc | System and method for implementing balanced rf fields in an ion trap device |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2466475C2 (en) | 2012-11-10 |
| EP2534670B1 (en) | 2018-07-25 |
| RU2010104792A (en) | 2011-08-20 |
| CN102754182A (en) | 2012-10-24 |
| EP2534670A1 (en) | 2012-12-19 |
| WO2011099889A1 (en) | 2011-08-18 |
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