CN102725022A - Device for infertility treatment - Google Patents
Device for infertility treatment Download PDFInfo
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- CN102725022A CN102725022A CN2010800431318A CN201080043131A CN102725022A CN 102725022 A CN102725022 A CN 102725022A CN 2010800431318 A CN2010800431318 A CN 2010800431318A CN 201080043131 A CN201080043131 A CN 201080043131A CN 102725022 A CN102725022 A CN 102725022A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0521—Genital electrodes
- A61N1/0524—Vaginal electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
Abstract
Provided is a device for infertility treatment includes a therapeutic electrode or a vagina probe (1) and a current generator (2), wherein the therapeutic electrode or the vagina probe (1) is placed in the corresponding female skin or female vagina in order to perform bionical electro stimulation to promote growth of endometrium. The current generator (2) is connected with the therapeutic electrode or the vagina probe (1) and exports current for bionical electro stimulation to the therapeutic electrode or the vagina probe (1). The invention reduces the vascular resistence through stimulating constriction and relaxation of vascular smooth muscles; it increases the blood circulation of the pelvis, endometrium and uterine muscles, and increases tissue nutrition; it stimulates the endometrium, and accelerates the tissue repair and the physiological functional recovery to promote growth of endometrium; endometrium thickness becomes greater, which facilitates the fertilized egg implantation. It is effective in infertility treatment, particularly effective to the infertility patients due to endometrium attenuation.
Description
A kind of equipment for infertile treatment
Technical field is the present invention relates to a kind of Medical Devices, more particularly, it relates to a kind of device and method for infertile treatment.The endometrium of background technology suitable thickness is one of the essential condition of gestation of succeeding during assisted reproduction.The endometrium of " thin " is also listed among the reason for implantation fails repeatedly.However, it is not good enough to endometrium thickness in practice the reason for and pathology be not yet fully apparent from, the cause of disease and pathology to endometrium " thin " still lack definite understanding so far.Because endometrial tissue the traumatic of research of drawing materials is limited to its research, the data studied on this respect is individual other to be related to experimental study mainly using the observation of Via vagina B ultrasound detection thickness.Most-often used thin endometrium standard is mainly the standard of B ultrasound detection in existing research：Ultrasonic measurement endometrium thickness 6-8 days or HCG days or HRT progestational hormone after late follicular phase or ovulation induction use day, and normal implantation inner film thickness need to be more than 8- 10mm.
The lower endometrium thickness measurement of ultrasound：On the maximum sagittal section image in uterus is freezed, measure and have a common boundary from the strong echo of side endometrium and sound Halo to the ultimate range between the strong echo of opposite side endometrium and sound Halo boundaries, i.e., two layers inner film thickness.
Have been reported：Estrogen level caused by a variety of causes and its effect it is not enough,
PC0S, endometrium wound such as A sheman ' s syndromes, Endometrial blood flow deficiency, blood vessels of endometrium growth defect etc. are related to endometrium " thin ".At present, for the known cause of disease thin endometrium person such as Asherman's syndrom, there is tuberculous foci etc., work as active treatment, dispel the cause of disease, adhesion release under feasible hysteroscope, and placement of intrauterine devices, while giving artificial cycle therapy to promote endometrial growth；There is tuberculosis infection to give antituberculosis therapy；Ovulation failure person can ovulation treatment；Thin endometrium for the indefinite cause of disease and the still thin person of above-mentioned cause of disease endometrium is removed, there has been proposed many treatment methods, including exogenous estrogen, low-dose aspirin, silaenafil, vitamin E, growth hormone, traditional Chinese medicine etc. are treated, attempt to supply by increasing internal estrogen, improving uterus, Ovarian Blood Flow, promote uterus body of gland and blood vessel hyperplasia, increase the approach such as endometrium Estrogen and progesterone receptors quantity to improve endometrium thickness and receptivity.But the clinical effectiveness of these current intervening measures still owes definite.The trial of these methods has certain curative effect to some cases but still has substantial portion of case reactionless to said medicine and treatment method.
The content of the invention
Present invention solves the technical problem that being to provide a kind of equipment for infertile treatment, to accelerate pelvic floor tissue reparation and physiological function to recover, promote endometrial growth, effectively treat infertile.The equipment not only can for the indefinite cause of disease thin endometrium and removed the still thin person of above-mentioned cause of disease endometrium, it will be apparent that increase endometrium thickness and increase regional flow, effectively treat infertile；It is right
Thin endometrium person such as Asherman's syndrom in the known cause of disease, there is the still thin person of the endometriums such as tuberculous foci, also can significantly increase endometrium thickness and increase regional flow.To solve the above problems, the present invention is adopted the following technical scheme that：
A kind of equipment for infertile treatment, it includes：
Therapeutic electrode or transvaginal probe, are accordingly placed in female skin or vagina and carry out bionical thing electrical stimulation to promote endometrial growth；And
Current feedback circuit, is connected with the therapeutic electrode or transvaginal probe and exports bionical thing electrical stimulation electric current to the therapeutic electrode or transvaginal probe.
Wherein, the current feedback circuit may include：
Power supply, console, single-chip microcomputer, voltage stabilizing and constant-current circuit, variable connector, the amplifier powered by power supply, wherein described single-chip microcomputer be connected with the console and receive the console signal perform dependent instruction, the amplifier is connected with the variable connector, the variable connector is connected with the single-chip microcomputer, variable connector described in the MCU driving and the amplifier operation, power supply export above-mentioned bionical thing electrical stimulation electric current through the voltage stabilizing and constant-current circuit processing.
Wherein, the current feedback circuit can export bionical thing electrical stimulation electric current according to the two stage segmentation rotations of first stage and second stage.
Wherein, the first stage current parameters scope is：
Frequency is 1-450 hertz, and pulsewidth is the microseconds of 50- 1000, time delay 0- 120 seconds, rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, time of having a rest is 0-30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.
The second stage current parameters scope is：
Frequency is 1-450 hertz, and pulsewidth is 100-2000 microseconds, time delay 0- 120 seconds, rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, time of having a rest is 0-30 seconds, and current waveform is sail type or rectangle unidirectional pulse.
Preferably, the specific frequency of first stage electric current is 60/ 100/60 hertz, and pulsewidth is 340/300/340 microsecond, rise time is 2 seconds, and plateau time is 3 seconds, and fall time is 0 second, time of having a rest is 6 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.
Preferably, the specific frequency of second stage electric current is 2 hertz, and pulsewidth is 2000 microseconds, and the time is 20 seconds, and current waveform is rectangle unidirectional pulse.
Wherein, the current feedback circuit control exports described bionical thing electrical stimulation electric current in assigned work duration.
Wherein, the assigned work duration scope can be 10-60 minutes.The transvaginal probe is by sonde body, signal input output interface and the signal conductor being connected between sonde body and signal input output interface are constituted, the body of the sonde body is insulator, it is made up of head and afterbody, its head is isometrical round bar shape, the front end of pole is in smooth arc surface, its afterbody immediately downstream of which there, in rod, it is connected with head smooth transition, if being equipped with dry contact electrode in the head surface of described sonde body, each contact electrode is connected with the contact conductor in sonde body, each contact conductor comes together in the tail end of sonde body, drawn by signal conductor and be connected to the latch in signal input output interface；
The signal input output interface of the current output interface of the current feedback circuit and therapeutic electrode or transvaginal probe is connected with to the therapeutic electrode or the corresponding bionical thing electrical stimulation electric current of transvaginal probe output.
The invention further relates to a kind of infertile method of external treatment, using current feedback circuit, being connected respectively with therapeutic electrode or transvaginal probe and being exported to the therapeutic electrode or transvaginal probe carries out bionical thing electrical stimulation to promote endometrial growth in bionical thing electrical stimulation electric current to female skin or vagina.
During using this method, current feedback circuit can export bionical thing electrical stimulation electric current according to the two stage segmentation rotations of foregoing first stage and second stage.
Compared with prior art, the invention has the advantages that：
The equipment of the present invention uses therapeutic electrode or transvaginal probe and current feedback circuit, bionical thing electrical stimulation electric current is exported to the therapeutic electrode or transvaginal probe by current feedback circuit, therapeutic electrode or transvaginal probe are placed in female skin or vagina and carry out bionical thing electrical stimulation to promote endometrial growth；Current feedback circuit exports bionical thing electrical stimulation to the therapeutic electrode or transvaginal probe.Due to exporting bionical thing electrical stimulation electric current by therapeutic electrode or transvaginal probe, vascular smooth muscle contraction and relaxation can be irritated, vascular resistence is reduced；Increase the blood circulation of pelvic cavity, endometrium and uterus muscle, increase histotrophic nutrition；Endometrium is irritated, acceleration of tissue repair and physiological function are recovered, it will be apparent that increase endometrium thickness and increase regional flow, be easy to egg implantation of being fertilized, can effectively treat infertile, especially to the thinning person of factor Endometrium, more effectively.
Using 26 patients of the therapy obtain promotion endometrial growth,
The obvious increased effect of thickness.Some cases successful pregnancies.
Brief description of the drawings
Fig. 1 is the principle schematic for the bionical thing electrical stimulation mode of smooth muscle that the present invention is used for the equipment of infertile treatment；
Fig. 2 is specific embodiment schematic block diagram of the present invention for the equipment of infertile treatment；
Fig. 3 is the present invention for preferred first stage current parameters and waveform diagram in the equipment of infertile treatment；
Fig. 4 is the present invention for preferred second stage current parameters and waveform diagram in the equipment of infertile treatment；
Fig. 5 is a kind of specific embodiment composition frame chart of the present invention for current feedback circuit in the equipment of infertile treatment；
Fig. 6 is a kind of specific embodiment circuit diagram of the present invention for realizing pressure-stabilizing constant flow circuit in the equipment of infertile treatment；Fig. 7 is a kind of specific embodiment circuit diagram of the present invention for realizing single-chip microcomputer and its peripheral circuit in the equipment of infertile treatment；
Fig. 8 is a kind of specific embodiment circuit diagram of the present invention for realizing drive amplification circuit in the equipment of infertile treatment；
Fig. 9 is one that the present invention pops one's head in for the equipment medial vagina of infertile treatment
Embodiment
The neururgic basic mode of body of apparatus embodiments people is neural reflex, the principle of bionical thing electrical stimulation treatment disease is to divide bad reflection process with benign irritate by the reflex arc in nervous system to correct partes corporis humani in the present invention, the tissue and organ that have occurred disease is set to recover normal function, disease is removed, with specific reference to Fig. 1, the present invention is to go to irritate vascular smooth muscle contraction and relaxation by the bionical thing electrical stimulation mode of smooth muscle, reduces vascular resistence；Increase the blood circulation of pelvic cavity, endometrium and uterus muscle, increase histotrophic nutrition；Endometrium is irritated, acceleration of tissue repair and physiological function are recovered, and promote endometrial growth, increase endometrium thickness and endometrium blood supply, can effectively treat infertile.
Specifically, with reference to Fig. 2, the present invention for infertile treatment equipment it include：Therapeutic electrode or transvaginal probe 1 and current feedback circuit 2, in specific treated, therapeutic electrode or corresponding be placed in female skin or vagina of transvaginal probe 1 carry out bionical thing electrical stimulation to promote endometrium to increase；
And current feedback circuit 2, it is connected with the therapeutic electrode or transvaginal probe 1 and exports bionical thing electrical stimulation electric current to the therapeutic electrode or transvaginal probe 1 in predetermined work duration.
Explanation is needed, the current feedback circuit can be defeated according to different phase transformations
Go out corresponding bionical thing electrical stimulation electric current, in addition, according to specific treatment situation, current feedback circuit also can be controlled in the described bionical thing electrical stimulation electric current of output in assigned work duration, and assigned work duration is adjusted according to actual therapeutic, for example, when implementing, assigned work duration may range from 10-60 minutes, and bionical thing electrical stimulation electric current can be divided into first stage electric current and second stage electric current rotation output.
In the present invention, following scope may be selected in the first stage current parameters scope：Frequency is 1-450 hertz, and pulsewidth is the microseconds of 50- 1000, time delay 0- 120 seconds, rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, time of having a rest is 0-30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.
And following scope may be selected in the second stage current parameters scope：
Frequency is 1-450 hertz, and pulsewidth is 100-2000 microseconds, time delay 0- 120 seconds, rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, time of having a rest is 0-30 seconds, and current waveform is sail type or rectangle unidirectional pulse.
As preferred specific embodiment, with reference to Fig. 3, a kind of preferred first stage current parameters and waveform can be：Frequency is 60/ 100/60 hertz, and pulsewidth is 340/300/340 microsecond, and the rise time is 2 seconds, and plateau time is 3 seconds, and fall time is 0 second, and the time of having a rest is 6 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero（Average value is zero）.
With reference to Fig. 4, a kind of preferred second stage current parameters and waveform can be：Frequency is 2 hertz, and pulsewidth is 2000 microseconds, and the time is 20 seconds, current waveform
For rectangle unidirectional pulse.
Above-mentioned first stage electric current and second stage current parameters and waveform, it is the parameter and waveform for the bionical thing electrical stimulation for having more preferable curative effect to above-mentioned acceleration of tissue repair and physiological function recovery, by checking, it is effectively reliable in actual therapeutic treatment, it particularly can effectively strengthen endometrium thickness, it is easy to endometrium implantation, has preferable therapeutic treatment effect to infertile.
Need above-mentioned current feedback circuit in explanation, the present invention to export bionical thing electrical stimulation electric current, different phase can be divided into, which kind of current parameters and wave form used, can be adjusted, repeated no more here according to actual therapeutic situation for different phase.
In addition, above-mentioned current feedback circuit can be realized when implementing using various ways, for example, the special bionical thing electrical stimulation electric current of circuit control output of design, for example, according to actual therapeutic situation, by circuit control, rotation exports above-mentioned first stage electric current and second stage electric current in assigned work duration when implementing；
Specifically, as a preferred specific embodiment, with reference to Fig. 5, current feedback circuit of the invention may include：
Power supply 11, the console 12 powered by power supply 11, single-chip microcomputer 13, voltage stabilizing and constant-current circuit 14, variable connector 15, amplifier 16, wherein described single-chip microcomputer 13 be connected with the console 12 and receive the console 12 signal perform dependent instruction, the amplifier 16 is connected with the variable connector 15, the variable connector 15 is connected with the single-chip microcomputer 13, the single-chip microcomputer 13 drives the variable connector 15 and the amplifier 16 to work, it is perverse that power supply 11 handles the above-mentioned imitative biological electricity of rotation output in predetermined work duration through the voltage stabilizing and constant-current circuit 14
Sharp first stage electric current and second stage electric current, when physical circuit is realized, above-mentioned single-chip microcomputer can for example use P I C 16F876, in addition, it is used as a kind of optional specific embodiment, pressure-stabilizing constant flow circuit, single-chip microcomputer and its peripheral circuit and drive amplification circuit can use the physical circuit such as Fig. 6-Fig. 8.
And in the present invention, therapeutic electrode or transvaginal probe can use various existing myoelectricity components, it is used as a kind of specific embodiment, with reference to Fig. 9, the transvaginal probe can be by sonde body 21, signal input output interface 22 and the signal conductor 23 being connected between sonde body 21 and signal input output interface 21 are constituted, the body of the sonde body 21 is insulator, it is made up of head and afterbody, its head is isometrical round bar shape, the front end of pole is in smooth arc surface, its afterbody immediately downstream of which there, in rod, it is connected with head smooth transition, if being equipped with dry contact electrode 24 in the head surface of described sonde body 21, each contact electrode 24 is connected with the contact conductor 25 in sonde body, each contact conductor 25 comes together in the tail end of sonde body, drawn by signal conductor 23 and be connected to the latch 26 in signal input output interface 22.
And the signal input output interface of the current output interface of heretofore described current feedback circuit and therapeutic electrode or transvaginal probe is connected with to the therapeutic electrode or the corresponding bionical thing electrical stimulation electric current of transvaginal probe output.
Equipment application embodiment
26 obtain the obvious increased case of promotion endometrial growth, thickness and are described below:26 patient ages are between 25-39 Sui.Cause the cause of disease that endometrium is thin：4 Asherman's syndroms, 22 unknown causes.Diagnosis is：17 are Stein-Leventhal syndrome, and 1 cases of uterine dystopy, 8 fallopian tubal reasons cause infertile.
For these patients, doctors have had taken up many treatment methods, including exogenous estrogen, low-dose aspirin, silaenafil, vitamin E, growth hormone, traditional Chinese medicine etc. are treated, attempt to supply by increasing internal estrogen, improving uterus, Ovarian Blood Flow, promote uterus body of gland and blood vessel hyperplasia, increase the approach such as endometrium Estrogen and progesterone receptors quantity to improve endometrium thickness and receptivity.But, by these treatments, these patients do not become pregnant.
It is as follows that 26 patients imitate Bioelectricity Treating parameter：
1st, the imitative Bioelectricity Treating parameter of case 2,6,8,9,20 is：First stage current parameters and waveform can be：Frequency is 60/ 100/60 hertz, and pulsewidth is 340/300/340 microsecond, and the rise time is 2 seconds, and parallel time is 3 seconds, and fall time is 0 second, and the time of having a rest is 6 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero（Average value is zero）.Second stage power frequency is 2 hertz, and pulsewidth is 2000 microseconds, and the time is 20 seconds, and current waveform is sail type or rectangle unidirectional pulse.
2nd, the imitative Bioelectricity Treating parameter of case 10,16,17,25 is：First stage power frequency is 1 hertz, and pulsewidth is 1000 microseconds, 1 second time delay, rise time is 10 seconds, and plateau time is 30 seconds, and fall time is 1 second, time of having a rest is 30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 450 hertz, and pulsewidth is 100 microseconds, and 1 second time delay, the rise time is 10 seconds, and plateau time is 30 seconds, and fall time is 10 seconds, and the time of having a rest is 30 seconds, and current waveform is sail type or rectangle unidirectional pulse.
, case 1,4,12 imitate Bioelectricity Treating parameter be：First stage power frequency is 450 hertz, and pulsewidth is 100 microseconds, 10 seconds time delays, rise time is 0 second, and plateau time is 20 seconds, and fall time is 10 seconds, time of having a rest is 30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 1 hertz, and pulsewidth is 2000 microseconds, and 120 seconds time delays, the rise time is 1 second, and plateau time is 10 seconds, and fall time is 1 second, and the time of having a rest is 10 seconds, and current waveform is sail type or rectangle unidirectional pulse.
, case 18,21,26 imitate Bioelectricity Treating parameter be：First stage power frequency is 1 hertz, and pulsewidth is 50 microseconds, and 0 second time delay, the rise time is 0 second, and plateau time is 30 seconds, and fall time is 0 second, and the time of having a rest is 0 second, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 450 hertz, and pulsewidth is 2000 microseconds, and 120 seconds time delays, the rise time is 10 seconds, and plateau time is 30 seconds, and fall time is 10 seconds, and the time of having a rest is 30 seconds, and current waveform is sail type or rectangle unidirectional pulse.
, case 3,7,11,15 imitate Bioelectricity Treating parameter be：First stage power frequency is 450 hertz, and pulsewidth is 1000 microseconds, 120 seconds time delays, rise time is 10 seconds, and plateau time is 30 seconds, and fall time is 10 seconds, time of having a rest is 30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 1 hertz, and pulsewidth is 100 microseconds, 0 second time delay, rise time
For 0 second, plateau time was 30 seconds, and fall time is 0 second, and the time of having a rest is 0 second, and current waveform is sail type or rectangle unidirectional pulse.
6th, the imitative Bioelectricity Treating parameter of case 5,19,22,24 is：First stage power frequency is 150 hertz, and pulsewidth is 450 microseconds, 30 seconds time delays, rise time is 3 seconds, and plateau time is 15 seconds, and fall time is 3 seconds, time of having a rest is 15 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 5 hertz, and pulsewidth is 2000 microseconds, and 0 second time delay, the rise time is 10 seconds, and plateau time is 20 seconds, and fall time is 5 seconds, and the time of having a rest is 15 seconds, and current waveform is sail type or rectangle unidirectional pulse.
7th, the imitative Bioelectricity Treating parameter of case 13,14,23 is：First stage power frequency is 200 hertz, and pulsewidth is 300 microseconds, 10 seconds time delays, rise time is 5 seconds, and plateau time is 30 seconds, and fall time is 5 seconds, time of having a rest is 30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.Second stage power frequency is 20 hertz, and pulsewidth is 2000 microseconds, and 0 second time delay, the rise time is 10 seconds, and plateau time is 30 seconds, and fall time is 10 seconds, and the time of having a rest is 0 second, and current waveform is sail type or rectangle unidirectional pulse.
The contrast of endometrium thickness and pregnancy outcome, see the table below before and after 26 patients are treated using the said equipment：
(my god）After being treated before treatment
1 11 79 without gestation
2 19 59 grow sign of being pregnent
3 14 48 without gestation
4 13 59 grow sign of being pregnent
5 11 47 without gestation
6 10 3 10 grow sign of being pregnent
7 14 59 without gestation
8 13 4 11 grow sign of being pregnent
9 8/12 6 11
^. cuns of long signs of being pregnent
10 9 50 07 without gestation
11 968 without gestation
12 979 grow sign of being pregnent
13 13 79 without gestation
14 11,/12 68 without gestation
15 11,/13 68 Endothelins are cancelled
16 10 5.5 8 without gestation
17 10 6 10 without gestation
18 13 6 11 without gestation
19 977 without gestation
20 11 5 10 grow sign of being pregnent
21 13 5 11 without gestation
22 956 without gestation
23 966 grow sign of being pregnent
24 22 6 7.4 grow sign of being pregnent
25 10 68 do not have temporarily
26 10 5 11 do not have temporarily
Average 8.75 scholars
Value 1. 55
To sum up, endometrium thickness is determined by B ultrasound and color Doppler determines the observation of blood flow under inner membrance, it is found that this treatment method has significant effect in above-mentioned two observation index：Significantly increase endometrium thickness and increase regional flow.The present invention goes to irritate vascular smooth muscle receipts by the bionical thing electrical stimulation mode of smooth muscle
Contracting and relaxation, reduce vascular resistence；Increase the blood circulation of pelvic cavity, endometrium and uterus muscle, increase histotrophic nutrition；Irritate endometrium, acceleration of tissue repair and physiological function are recovered, as a result of the parameter characteristic for recovering to have the bionical thing electrical stimulation of more preferable curative effect to acceleration of tissue repair and physiological function, promote endometrial growth, add endometrium thickness, it is easy to egg implantation of being fertilized, can effectively treats infertile.Described above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; some improvements and modifications can also be made, these improvements and modifications also should be regarded as protection scope of the present invention.
Claims (13)
- Claim1st, a kind of equipment for infertile treatment, it is characterised in that including：Therapeutic electrode or transvaginal probe, are accordingly placed in female skin or vagina and carry out bionical thing electrical stimulation to promote endometrial growth；AndCurrent feedback circuit, is connected with the therapeutic electrode or transvaginal probe and exports bionical thing electrical stimulation electric current to the therapeutic electrode or transvaginal probe.2nd, the equipment according to claim 1, it is characterised in that the current feedback circuit includes：Power supply, console, single-chip microcomputer, voltage stabilizing and constant-current circuit, variable connector, the amplifier powered by power supply, wherein described single-chip microcomputer be connected with the console and receive the console signal perform dependent instruction, the amplifier is connected with the variable connector, the variable connector is connected with the single-chip microcomputer, variable connector described in the MCU driving and the amplifier operation, power supply export above-mentioned bionical thing electrical stimulation electric current through the voltage stabilizing and constant-current circuit processing.3rd, the equipment according to claim 1, it is characterised in that the current feedback circuit exports bionical thing electrical stimulation electric current according to the two stage segmentation rotations of first stage and second stage.4th, the equipment according to claim 3, it is characterised in that described One stage current parameters scope is as follows：Frequency is 1-450 hertz, and pulsewidth is the microseconds of 50- 1000, and waveform is：Time delay 0- 120 seconds, the rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, and the time of having a rest is 0-30 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.5th, the equipment according to claim 3 or 4, it is characterised in that the second stage current parameters scope is as follows：Frequency is 1-450 hertz, and pulsewidth is 100-2000 microseconds, time delay 0- 120 seconds, rise time is 0- 10 seconds, and plateau time is 0-30 seconds, and fall time is 0- 10 seconds, time of having a rest is 0-30 seconds, and current waveform is sail type or rectangle unidirectional pulse.6th, the equipment according to claim 3, it is characterised in that the current feedback circuit control exports described bionical thing electrical stimulation electric current in assigned work duration.7th, the equipment according to claim 6, it is characterised in that the assigned work duration scope is 10-60 minutes.8th, the equipment according to claim 1, it is characterised in that the transvaginal probe is made up of sonde body, signal input output interface and the signal conductor being connected between sonde body and signal input output interface, the body of the sonde body is exhausted Edge body, it is made up of head and afterbody, its head is isometrical round bar shape, and the front end of pole is in smooth arc surface, its afterbody immediately downstream of which there, in rod, it is connected with head smooth transition, if the head surface in described sonde body is equipped with dry contact electrode, each contact electrode is connected with the contact conductor in sonde body, each contact conductor comes together in the tail end of sonde body, is drawn by signal conductor and is connected to the latch in signal input output interface；The signal input output interface of the current output interface of the current feedback circuit and therapeutic electrode or transvaginal probe is connected with to the therapeutic electrode or the corresponding bionical thing electrical stimulation electric current of transvaginal probe output.9th, the equipment according to claim 4, it is characterized in that, the specific frequency of first stage electric current is 60/ 100/60 hertz, pulsewidth is 340/300/340 microsecond, rise time is 2 seconds, and plateau time is 3 seconds, and fall time is 0 second, time of having a rest is 6 seconds, and current waveform is the rectangle bidirectional pulse that average value is zero.10th, equipment according to claim 5, it is characterised in that the specific frequency of second stage electric current is 2 hertz, pulsewidth is 2000 microseconds, and the time is 20 seconds, and current waveform is rectangle unidirectional pulse.11, a kind of infertile method of external treatment, using current feedback circuit, is connected with therapeutic electrode or transvaginal probe and is carried out into the therapeutic electrode or the bionical thing electrical stimulation electric current of transvaginal probe output to female skin or vagina bionical Thing electro photoluminescence is to promote endometrial growth.12nd, the infertile method of external treatment according to claim 11, it is characterised in that current feedback circuit exports bionical thing electrical stimulation currents according to the two stages segmentation rotations of first stage and second stage.13rd, the bionical thing electrical stimulation current feedback circuit described in claim 1 is infertile for external treatment.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2010/073570 WO2011150576A1 (en) | 2010-06-04 | 2010-06-04 | Device for infertility treatment |
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| CN102725022A true CN102725022A (en) | 2012-10-10 |
| CN102725022B CN102725022B (en) | 2014-12-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201080043131.8A Active CN102725022B (en) | 2010-06-04 | 2010-06-04 | Device for infertility treatment |
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| CN (1) | CN102725022B (en) |
| WO (1) | WO2011150576A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108096704A (en) * | 2017-12-07 | 2018-06-01 | 南京麦澜德医疗科技有限公司 | For treating infertile device, system and carrying out Humoral immunity, the method that neural channels and collaterals are adjusted |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301567B (en) * | 2012-03-16 | 2016-04-06 | 女康乐公司 | A kind of therapeutic apparatus repairing vagina tissue |
| CN113082516A (en) * | 2021-04-01 | 2021-07-09 | 悦一美(广州)科技有限公司 | Pelvic floor muscle repair probe, equipment and control method of equipment |
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| CN2848126Y (en) * | 2005-12-15 | 2006-12-20 | 广州市杉山医疗器械实业有限公司 | Vagina and anus probe |
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| CN1065599A (en) * | 1992-04-10 | 1992-10-28 | 孔斌 | Multifunction medical instrument |
| CN1118578A (en) * | 1993-01-11 | 1996-03-13 | 布伦特·卡曼 | Method of varying appropriate muscle strength of a person to alleviate urinary or fecalurgency or incontinence or vaginal or bladder spasms |
| CN1079915A (en) * | 1993-05-06 | 1993-12-29 | 查方刚 | Bioelectro modulating charge therapeutical instrument |
| CN1193539A (en) * | 1998-03-03 | 1998-09-23 | 李永忠 | Method and apparatus for preventing and curing sterility and sexual disorder |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108096704A (en) * | 2017-12-07 | 2018-06-01 | 南京麦澜德医疗科技有限公司 | For treating infertile device, system and carrying out Humoral immunity, the method that neural channels and collaterals are adjusted |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011150576A1 (en) | 2011-12-08 |
| CN102725022B (en) | 2014-12-31 |
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