CN102697475A - Doppler laser OCT (optical coherence tomography) ventriculoscope system - Google Patents
Doppler laser OCT (optical coherence tomography) ventriculoscope system Download PDFInfo
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- CN102697475A CN102697475A CN2012100174748A CN201210017474A CN102697475A CN 102697475 A CN102697475 A CN 102697475A CN 2012100174748 A CN2012100174748 A CN 2012100174748A CN 201210017474 A CN201210017474 A CN 201210017474A CN 102697475 A CN102697475 A CN 102697475A
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Abstract
The invention belongs to the field of medical instruments, and particularly discloses a Doppler laser OCT (optical coherence tomography) ventriculoscope system, which comprises a ventriculoscope, a cold light source main unit and a camera main unit, wherein the cold light source main unit and the camera main unit are connected with the ventriculoscope system. The ventriculoscope is provided with a Doppler laser data acquisition module and an OCT data acquisition module and is connected with a Doppler processing main unit used for analyzing data acquired by the Doppler laser data acquisition module and an OCT processing main unit used for analyzing data acquired by the OCT data acquisition module. Since the Doppler laser data acquisition module and the OCT data acquisition module are integrated on one telescopic head of a combined module and used with the Doppler processing main unit and the OCT processing main unit for processing, more accurate dynamic images and more precise sectional lesion images of blood vessels in cranial cavities and on surfaces of brain tissues can be acquired, and a more precise data support can be supplied for doctors to make diagnosis and treatment.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of laser doppler OCT ventricularendoscope system.
Background technology
Ventricularendoscope is diagnosing patients brain section pathological changes, assessment cerebral tissue function, the accuracy rate that improves operation and the important medical apparatus and instruments of success rate.
Doppler principle all is used widely in every field, utilizes the Doppler effect of laser beam in the industry, is used for the speed of Measuring Object, and its degree of accuracy is high; Medically utilize hyperacoustic Doppler effect, observation patient body situation.The laser doppler technology slowly also gets into medical domain at present; Utilize the Doppler effect of laser to measure the microcirculation blood flow of various tissues and organ with the mode of noinvasive or Wicresoft; In addition can also do series of analysis calculates; Comprise microcirculatory hemodynamics variation, and heart is beated synchronously even double pulse etc., accomplish the purpose of accurate monitoring.
Equally; OCT (Optical Coherence Tomography; Optical Coherence Tomography Imaging Technology) utilizes the weak coherent light principle of interference; Detect the backscatter signals of tested tissue different depth, and obtain organizing two dimension or three dimensional depth structural images, have characteristics such as radiationless, non-intruding, high-resolution and high detection sensitivity through scanning.
The OCT technology has obtained effective application in ophthalmologic examination, and gets involved in the human organ, the microminiaturization of OCT technology is applied to intraorganic disease detect, and is not still effectively carried out at present.
But at present, in ventricularendoscope, still there are not fine application laser doppler technology and OCT technology.If; Ventricularendoscope can be gathered the advantage of laser doppler technology and OCT technology; With accurate more dynamic image of the top layer blood vessel that obtains brainpan intracavity and cerebral tissue and meticulousr tomography pathological changes image, further improve the accuracy of diagnosis and the success rate of treatment.
Therefore, design is a kind of extremely urgent with laser doppler technology, ventricularendoscope system that OCT is technological to be used in combination with ventricularendoscope.
Summary of the invention
The object of the present invention is to provide a kind of laser doppler OCT ventricularendoscope system; The advantage of set laser doppler technology and OCT technology; With accurate more dynamic image of the top layer blood vessel that obtains brainpan intracavity and cerebral tissue and meticulousr tomography pathological changes image, further improve the accuracy of diagnosis and the success rate of treatment.
For realizing the foregoing invention purpose, technical scheme that the present invention adopts is following:
A kind of laser doppler OCT ventricularendoscope system; Comprise ventricularendoscope and the cold light source main frame that is connected with this ventricularendoscope and shooting main frame; Said ventricularendoscope is provided with laser doppler data acquisition module and OCT data acquisition module; On said ventricularendoscope, also be connected with the data that said laser doppler data acquisition module is collected and carry out Doppler's processing host of analyzing and processing, on said ventricularendoscope, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
In the described laser doppler OCT ventricularendoscope system, its laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
In the described laser doppler OCT ventricularendoscope system, its Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
In the described laser doppler OCT ventricularendoscope system, its ventricularendoscope includes a work end, cold light source joint, data connector, control module, instrument channel, intake tunnel and exhalant canal; Said laser doppler data acquisition module and OCT data acquisition module are arranged on the ventricularendoscope; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
In the described laser doppler OCT ventricularendoscope system, the diameter of its telescopic head is smaller or equal to 3 millimeters.
In the described laser doppler OCT ventricularendoscope system, on the first end of said work end, also be provided with optical fibers, optical lens, outlet, water inlet and apparatus and import and export.
In the described laser doppler OCT ventricularendoscope system, its apparatus is imported and exported diameter more than or equal to 3 millimeters, and said water inlet and outlet diameter are more than or equal to 1 millimeter.
In the described laser doppler OCT ventricularendoscope system; It is 1.5~3.0 millimeters CCD optical lens that its optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
In the described laser doppler OCT ventricularendoscope system, its work end is processed by hard material, and this hard material is selected hard materials such as medical stainless steel for use, and the first end of this hard work end is blunt type; The diameter of said work end is 180~250 millimeters smaller or equal to 10 millimeters, length.
Its principle of the present invention is at integrated laser doppler module of endoscopic technique and OCT module; Make the doctor can obtain the laser doppler image and the OCT image in patient affected part simultaneously through once performing the operation; Accomplish without any letup, reduce the diagnosis basis that damages and obtain enriching more.The laser doppler technology is to utilize the doppler principle of light wave; Utilize laser beam irradiation and write down the light of reflection, transmission, scattering and the data behind the reference light frequency modulation; Come accurately to survey the blood flow velocity and calculating blood flow flow of blood vessel, the laser doppler technology has than the more accurate certainty of measurement of doppler technique; The OCT module utilizes means of optical coherence tomography, carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.The vascular flow of brainpan intracavity and cerebral tissue blood vessel and tissue substance thereof is dynamically schemed, and the tomography pathological changes image of tachogram and brainpan intracavity and cerebral tissue etc. are for doctor's diagnosis provides more accurate accurate data support.
Compared with prior art, the invention has the beneficial effects as follows:
The laser doppler measuring technique has than the more accurate characteristics of doppler technique, can obtain the accurate more dynamic image of top layer blood vessel of brainpan intracavity and cerebral tissue; OCT techniques make use means of optical coherence tomography carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.Two images perhaps are simultaneously displayed in the display respectively, can improve the accuracy of diagnosis patient brain section pathological changes, assessment cerebral tissue function, further improve the accuracy rate and the success rate of operation.
Description of drawings
The picture that this description of drawings provided is used for auxiliary to further understanding of the present invention, constitutes the application's a part, does not constitute to improper qualification of the present invention, in the accompanying drawings:
Fig. 1 is a system structure sketch map of the present invention;
Fig. 2 is a ventricularendoscope structural representation of the present invention;
Fig. 3 is the local structure for amplifying sketch map of the first end of work of the present invention end.Diagram:
1, ventricularendoscope 2, cold light source main frame
3, shooting main frame 4, laser doppler processing host
5, OCT processing host 6, operation keyboard or handheld device
7, Doppler and OCT monitor 8, endoscope's monitor
11, work end 12, cold light source joint
13, data connector 14, instrument channel
15, intake tunnel 16, exhalant canal
17, control module 111, first end
1111, optical fibers 1112, optical lens
1113, apparatus import and export 1114, water inlet
1115, outlet 1116, telescopic head
11161, Laser emission end 11162, laser pick-off end
11163, OCT data acquisition module 11164, micromotor
The specific embodiment
To combine accompanying drawing and practical implementation method to specify the present invention below, be used for explaining the present invention in schematic enforcement of the present invention and explanation, but not as to qualification of the present invention.
As shown in Figure 1; Laser doppler OCT ventricularendoscope disclosed by the invention system; Mainly comprise ventricularendoscope 1 and the cold light source main frame 2 that is connected with this ventricularendoscope 1, shooting main frame 3, laser doppler processing host 4, OCT processing host 5, also comprise operation keyboard or handheld device 6, Doppler and OCT monitor 7 and endoscope's monitor 8 these conventional input-output equipment certainly.
As shown in Figure 1; Reduce cost in order to economize on resources; Shared monitor-Doppler of laser doppler processing host and OCT processing host and OCT monitor 7 show through split screen in the present embodiment, can certainly use different monitors to be used for showing respectively.
As shown in Figure 2, ventricularendoscope 1 comprises work end 11, cold light source joint 12, data connector 13, control module 17, instrument channel 14, intake tunnel 15 and exhalant canal 16.Its work end 11 is processed by hard material, and this hard material is selected hard materials such as medical stainless steel for use.The diameter of this work end 11 is 180~250 millimeters smaller or equal to 10 millimeters, length; In order to prevent to damage mucosal tissue, the first end of this hard work end is blunt type, and so-called blunt type is for there are stiff corner angle in head, such as circular, oval or other do not have the shape of stiff corner angle.
Fig. 3 is the local structure for amplifying sketch map of the first end 111 of work of the present invention end 11, and so-called first end promptly is the front end position, and its structure is specifically as shown in the figure:
This elder generation end 111 comprises optical fibers 1111 and is arranged at optical lens 1112, apparatus import and export 1113, water inlet 1114, outlet 1115 and the telescopic head 1116 on this optical fibers 1111 that this telescopic head 1116 comprises transparent outer cover and is installed in Laser emission end 11161, laser pick-off end 11162, OCT data acquisition module 11163 and the micromotor 11164 in the transparent outer cover.Wherein, Laser emission end 11161 constitutes the laser doppler data acquisition module with laser pick-off end 11162; Wherein, OCT data acquisition module 11163 comprises the conventional structures such as prism, GRIN Lens and optical fiber tissue that comprise; Wherein, telescopic head 1116 can stretch out the end face with withdrawal work end 11 under the effect of its micromotor 11164, also can at the uniform velocity rotate by 360 degree, observes with convenient.Wherein, use for ease, the diameter of telescopic head 1116 is smaller or equal to 3 millimeters, and apparatus is imported and exported 1113 diameters more than or equal to 3 millimeters, and water inlet 1114 and outlet 1115 diameters are more than or equal to 1 millimeter.Wherein, it is 1.5~3.0 millimeters CCD optical lens that optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
The present invention with laser doppler module (laser doppler data acquisition module) and OCT module (OCT data acquisition module) under not interferential situation each other; Design Treatment through microminiaturization; Be integrated on the telescopic head 1116 on the first end 111 that is positioned at work end 11; This telescopic head 1116 can be released the end face realization work in addition of work end 11 through the transmission of micromachine 11164, and the inoperative stage is through the transmission of micromachine 11164; In 11 end faces of withdrawal work end, to make the usefulness of protection.
Operation keyboard among the present invention or handheld device 6, its function are that laser doppler main frame and OCT processing host are controlled, and scan mode and display mode etc. such as are switched at effect.
Laser doppler data acquisition module among the present invention and the combined effect of laser doppler processing host; The laser doppler processing host is carried out analyzing and processing to the data that the doppler data acquisition module collects; In can the measure cerebral cranial cavity and the microcirculation blood flow of the blood vessel of cerebral tissue; Whole microcirculatory perfusion amounts comprise that blood capillary, arteriole, venule and arteriovenous anastomosis prop up, and can monitor senior clinical datas such as microcirculatory hemodynamics variation through computational analysis.Described laser doppler processing host can carry powerful data base and powerful software test bag, to satisfy the different needs of the different purpose doctors of section.
OCT data acquisition module among the present invention and the combined effect of OCT processing host; The brainpan intracavity that the OCT data acquisition module collected that the OCT processing host is right and the layer data of cerebral tissue and Treatment Analysis in addition; The faultage image that display resolution carries out with micron level, and output to the display demonstration.
Ventricularendoscope among the present invention has possessed all optical observation functions of general ventricularendoscope; Among normal observation carries out or after; Can be through opening laser doppler processing host 4, OCT processing host 5 respectively or simultaneously; The laser doppler data acquisition module and the OCT data acquisition module that start on the telescopic head carry out laser doppler scanning and the observation of OCT tomoscan, and the telescopic head duration of work does not disturb the application of the common function of ventricularendoscope.
More than the technical scheme that the embodiment of the invention provided has been carried out detailed introduction; Used concrete example among this paper the principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment only is applicable to the principle that helps to understand the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, the part that on the specific embodiment and range of application, all can change, in sum, this description should not be construed as limitation of the present invention.
Claims (9)
1. a laser doppler OCT ventricularendoscope system comprises ventricularendoscope and the cold light source main frame that is connected with this ventricularendoscope and shooting main frame, it is characterized in that:
Said ventricularendoscope is provided with laser doppler data acquisition module and OCT data acquisition module;
On said ventricularendoscope, also be connected with the data that said laser doppler data acquisition module is collected and carry out Doppler's processing host of analyzing and processing;
On said ventricularendoscope, also be connected with the data that said OCT data acquisition module is collected and carry out the OCT processing host of analyzing and processing.
2. laser doppler OCT ventricularendoscope according to claim 1 system is characterized in that:
Said laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
3. laser doppler OCT ventricularendoscope according to claim 1 system is characterized in that:
Said Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
4. according to each described laser doppler OCT ventricularendoscope system of claim 1 to 3, it is characterized in that:
Said ventricularendoscope includes work end, cold light source joint, data connector, control module, instrument channel, intake tunnel and exhalant canal;
Said laser doppler data acquisition module and OCT data acquisition module are arranged on the ventricularendoscope; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
5. laser doppler OCT ventricularendoscope according to claim 4 system is characterized in that:
The diameter of said telescopic head is smaller or equal to 3 millimeters.
6. laser doppler OCT ventricularendoscope according to claim 4 system is characterized in that:
On the first end of said work end, also being provided with optical fibers, optical lens, outlet, water inlet and apparatus imports and exports.
7. laser doppler OCT ventricularendoscope according to claim 6 system is characterized in that:
Said apparatus is imported and exported diameter more than or equal to 3 millimeters, and said water inlet and outlet diameter are more than or equal to 1 millimeter.
8. laser doppler OCT ventricularendoscope according to claim 6 system is characterized in that:
It is 1.5~3.0 millimeters CCD optical lens that said optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
9. laser doppler OCT ventricularendoscope according to claim 6 system is characterized in that:
Said work end is processed by hard material, and the first end of this hard work end is blunt type;
The diameter of said work end is the 180-250 millimeter smaller or equal to 10 millimeters, length.
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CN2012100174748A CN102697475A (en) | 2012-01-18 | 2012-01-18 | Doppler laser OCT (optical coherence tomography) ventriculoscope system |
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CN2012100174748A CN102697475A (en) | 2012-01-18 | 2012-01-18 | Doppler laser OCT (optical coherence tomography) ventriculoscope system |
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CN101662980A (en) * | 2007-01-19 | 2010-03-03 | 桑尼布鲁克健康科学中心 | The sweep mechanism that is used for imaging probe |
CN201675918U (en) * | 2010-03-24 | 2010-12-22 | 广州市番禺区胆囊病研究所 | Hard electronic cerebral ventricle lens |
CN202426509U (en) * | 2012-01-18 | 2012-09-12 | 广州宝胆医疗器械科技有限公司 | Doppler laser OCT (optical coherence tomography) ventriculoscope system |
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2012
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Patent Citations (10)
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CN85205102U (en) * | 1985-11-26 | 1986-12-17 | 薛络 | Z-formed, hard colonoscope composed of annularly distributed optical fibre and cold light source |
US4920967A (en) * | 1986-07-18 | 1990-05-01 | Pfizer Hospital Products Group, Inc. | Doppler tip wire guide |
CN87216008U (en) * | 1987-12-02 | 1988-12-07 | 支道钤 | Hard tube tracheal mirror |
US4945896A (en) * | 1989-01-24 | 1990-08-07 | Gade George F | Surgical retractor assembly having tissue viability sensor embedded therein |
CN2049518U (en) * | 1989-04-06 | 1989-12-20 | 山东省肿瘤防治研究院 | Hard cold-light illuminator of endoscope |
CN1149821A (en) * | 1994-05-31 | 1997-05-14 | 阿弗拉汉姆·马耶父斯基 | Tissue monitor |
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CN101662980A (en) * | 2007-01-19 | 2010-03-03 | 桑尼布鲁克健康科学中心 | The sweep mechanism that is used for imaging probe |
CN201675918U (en) * | 2010-03-24 | 2010-12-22 | 广州市番禺区胆囊病研究所 | Hard electronic cerebral ventricle lens |
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Application publication date: 20121003 |