CN102697471A - Doppler laser optical coherence tomography (OCT) protoscope system - Google Patents
Doppler laser optical coherence tomography (OCT) protoscope system Download PDFInfo
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- CN102697471A CN102697471A CN2012100180698A CN201210018069A CN102697471A CN 102697471 A CN102697471 A CN 102697471A CN 2012100180698 A CN2012100180698 A CN 2012100180698A CN 201210018069 A CN201210018069 A CN 201210018069A CN 102697471 A CN102697471 A CN 102697471A
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Abstract
The invention belongs to the field of medical instruments, and specifically discloses a Doppler laser optical coherence tomography (OCT) protoscope system. The Doppler laser OCT protoscope system comprises a protoscope, and a cold light source host and a photographic host which are connected with the protoscope, wherein a Doppler laser data acquisition module and an OCT data acquisition module are arranged on the protoscope, and the protoscope is also connected with a Doppler processing host which analyzes and processes the data which is acquired by the Doppler laser data acquisition module, and is further connected with an OCT processing host which analyzes and processes the data which is acquired by the OCT data acquisition module. The Doppler laser data acquisition module and the OCT data acquisition module are integrated on a mixed module, namely a flexible head, through coordinating with a Doppler host and an OCT host to process, the more accurate dynamic images and more exquisite tomographic lesion images of surface vessels between procto tract walls are obtained, so precise and exact data support is provided for the diagnosis and treatment of doctors.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of laser doppler OCT enteroscope system.
Background technology
The anorectal mirror; It is the important medical apparatus and instruments of current diagnosis anorectal tract disease; It is through the electronic image pickup device that is installed on its front end image between the anus intestinal walls to be transmitted in the electronic computer processing center, after be shown on the monitor screen, can be observed the minor variations between the anus intestinal walls.
Doppler principle all is used widely in every field, utilizes the Doppler effect of laser beam in the industry, is used for the speed of Measuring Object, and its degree of accuracy is high; Medically utilize hyperacoustic Doppler effect, observation patient body situation.The laser doppler technology slowly also gets into medical domain at present; Utilize the Doppler effect of laser to measure the microcirculation blood flow of various tissues and organ with the mode of noinvasive or Wicresoft; In addition can also do series of analysis calculates; Comprise microcirculatory hemodynamics variation, and heart is beated synchronously even double pulse etc., accomplish the purpose of accurate monitoring.
Equally; OCT (Optical Coherence Tomography; Optical Coherence Tomography Imaging Technology) utilizes the weak coherent light principle of interference; Detect the backscatter signals of tested tissue different depth, and obtain organizing two dimension or three dimensional depth structural images, have characteristics such as radiationless, non-intruding, high-resolution and high detection sensitivity through scanning.
The OCT technology has obtained effective application in ophthalmologic examination, and gets involved in the human organ, the microminiaturization of OCT technology is applied to intraorganic disease detect, and is not still effectively carried out at present.
But at present, in the anorectal mirror, still there are not fine application laser doppler technology and OCT technology.If; The anorectal mirror can be gathered the advantage of laser doppler technology and OCT technology; Accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between the anus intestinal walls further improve the accuracy of diagnosis and the success rate of treatment.
Therefore, design is a kind of extremely urgent with the enteroscope system that laser doppler is technological, OCT is technological to be used in combination with the anorectal mirror.
Summary of the invention
The object of the present invention is to provide a kind of laser doppler OCT enteroscope system; The advantage of set laser doppler technology and OCT technology; Accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between the anus intestinal walls further improve the accuracy of diagnosis and the success rate of treatment.
For realizing the foregoing invention purpose, technical scheme that the present invention adopts is following:
A kind of laser doppler OCT enteroscope system; Comprise anorectal mirror and the cold light source main frame that is connected with this anorectal mirror and shooting main frame; Said anorectal mirror is provided with laser doppler data acquisition module and OCT data acquisition module; On said anorectal mirror, also be connected with Doppler's processing host that the data that said laser doppler data acquisition module is collected are carried out analyzing and processing, on said anorectal mirror, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
In the said laser doppler OCT enteroscope system, its laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
In the said laser doppler OCT enteroscope system, its Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
In the said laser doppler OCT enteroscope system, its anorectal mirror comprises work end, cold light source joint, data connector, control module and instrument channel; Said laser doppler data acquisition module and OCT data acquisition module are arranged on the anorectal mirror; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
In the said laser doppler OCT enteroscope system, the diameter of its telescopic head is smaller or equal to 3 millimeters.
In the said laser doppler OCT enteroscope system, on the first end of said work end, also be provided with optical fibers, optical lens and apparatus and import and export.
In the said laser doppler OCT enteroscope system, its work end is processed by hard material, and the first end of this hard work end is blunt type; The diameter of this hard work end is the 300-450 millimeter smaller or equal to 20 millimeters, length.
In the said laser doppler OCT enteroscope system; It is the CCD optical lens of 1.5-3.0 millimeter that its optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
Its principle of the present invention is at integrated laser doppler module of endoscopic technique and OCT module; Make the doctor can obtain the laser doppler image and the OCT image in patient affected part simultaneously through once performing the operation; Accomplish without any letup, reduce the diagnosis basis that damages and obtain enriching more.The laser doppler technology is to utilize the doppler principle of light wave; Utilize laser beam irradiation and write down the light of reflection, transmission, scattering and the data behind the reference light frequency modulation; Come accurately to survey the blood flow velocity and calculating blood flow flow of blood vessel, the laser doppler technology has than the more accurate certainty of measurement of doppler technique; The OCT module utilizes means of optical coherence tomography, carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.The vascular flow of blood vessel and tissue substance thereof is dynamically schemed between the anus intestinal walls, and the tomography pathological changes image between tachogram and anus intestinal walls etc. are for doctor's diagnosis provides more accurate accurate data support.
Compared with prior art, the invention has the beneficial effects as follows:
The laser doppler measuring technique has than the more accurate characteristics of doppler technique, can obtain blood vessel accurate more dynamic image in top layer between the anus intestinal walls; OCT techniques make use means of optical coherence tomography carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.Two images perhaps are simultaneously displayed in the display respectively, can improve the accuracy of diagnosis patient anorectal road pathological changes, assessment anorectal road function, further improve the accuracy rate and the success rate of operation.
Description of drawings
The picture that this description of drawings provided is used for auxiliary to further understanding of the present invention, constitutes the application's a part, does not constitute to improper qualification of the present invention, in the accompanying drawings:
Fig. 1 is a system structure sketch map of the present invention;
Fig. 2 is the structural representation of anorectal mirror of the present invention;
Fig. 3 is the local structure for amplifying sketch map of the first end of work of the present invention end.Diagram:
1, anorectal mirror 2, cold light source main frame
3, shooting main frame 4, laser doppler processing host
5, OCT processing host 6, operation keyboard or handheld device
7, Doppler and OCT monitor 8, endoscope's monitor
11, work end 12, cold light source joint
13, data connector 14, instrument channel
15, control module 111, first end
1111, optical fibers 1112, optical lens
1113, apparatus import and export 1114, telescopic head
11141, Laser emission end 11142, laser pick-off end
11143, OCT data acquisition module 11144, micromotor
The specific embodiment
To combine accompanying drawing and practical implementation method to specify the present invention below, be used for explaining the present invention in schematic enforcement of the present invention and explanation, but not as to qualification of the present invention.
As shown in Figure 1; Laser doppler OCT enteroscope system disclosed by the invention; Mainly comprise anorectal mirror 1 and the cold light source main frame 2 that is connected with this anorectal mirror 1, shooting main frame 3, laser doppler processing host 4, OCT processing host 5, also comprise operation keyboard or handheld device 6, Doppler and OCT monitor 7 and endoscope's monitor 8 these conventional input-output equipment certainly.
As shown in Figure 1, reduce cost in order to economize on resources, shared monitor-Doppler of laser doppler processing host and OCT processing host and OCT monitor 7 show through split screen in the present embodiment, can certainly use different monitors to be used for showing respectively.
Fig. 2 is the structural representation of anorectal mirror of the present invention, and as shown in the figure, it comprises that said anorectal mirror comprises work end 11, cold light source joint 12, data connector 13, control module 15 and instrument channel 14.Its work end 11 is processed by hard material, and this hard material is selected materials such as medical stainless steel for use.The diameter of this hard work end is the 300-450 millimeter smaller or equal to 20 millimeters, length; Elder generation end 111 is for fear of the needs of damage mucosal tissue; Need be designed to blunt type to first end; So-called blunt type is for there are stiff corner angle in head, such as circular, oval or other do not have the shape of stiff corner angle; It is the CCD optical lens of 1.5-3.0 millimeter that optical lens on the said work end adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
Fig. 3 is the local structure for amplifying sketch map of the first end 111 of work of the present invention end 11, and so-called first end promptly is the front end position, and its structure is specifically as shown in the figure:
This elder generation end 111 comprises optical fibers 1111 and is arranged at optical lens 1112, apparatus import and export 1113 and the telescopic head 1114 on this optical fibers 1111 that this telescopic head 1114 comprises transparent outer cover and is installed in Laser emission end 11141, laser pick-off end 11142, OCT data acquisition module 11143 and the micromotor 11144 in the transparent outer cover.Wherein, Laser emission end 11141 constitutes the laser doppler data acquisition module with laser pick-off end 11142; Wherein, OCT data acquisition module 11143 comprises the conventional structures such as prism, GRIN Lens and optical fiber tissue that comprise; Wherein, telescopic head 1114 can stretch out the end face with withdrawal work end 11 under the effect of its micromotor 11144, also can at the uniform velocity rotate by 360 degree, observes with convenient.Wherein, use for ease, the diameter of telescopic head 1114 is smaller or equal to 3 millimeters.
The present invention with laser doppler module (laser doppler data acquisition module) and OCT module (OCT data acquisition module) under not interferential situation each other; Design Treatment through microminiaturization; Be integrated on the telescopic head 1114 on the first end 111 that is positioned at work end 11; This telescopic head 1114 can be released the end face realization work in addition of work end 11 through the transmission of micromachine 11144, and the inoperative stage is through the transmission of micromachine 11144; In 11 end faces of withdrawal work end, to make the usefulness of protection.
Operation keyboard among the present invention or handheld device 6, its function are that laser doppler main frame and OCT processing host are controlled, and scan mode and display mode etc. such as are switched at effect.
Laser doppler data acquisition module among the present invention and the combined effect of laser doppler processing host; The laser doppler processing host is carried out analyzing and processing to the data that the doppler data acquisition module collects; Can measure the microcirculation blood flow of blood vessel between the anus intestinal walls; Whole microcirculatory perfusion amounts comprise that blood capillary, arteriole, venule and arteriovenous anastomosis prop up, and can monitor senior clinical datas such as microcirculatory hemodynamics variation through computational analysis.Described laser doppler processing host can carry powerful data base and powerful software test bag, to satisfy the different needs of the different purpose doctors of section.
OCT data acquisition module among the present invention and the combined effect of OCT processing host; Right anus intestinal walls phantom data that the OCT data acquisition module collected of OCT processing host and Treatment Analysis in addition; The faultage image that display resolution carries out with micron level, and output to the display demonstration.
Anorectal mirror among the present invention has possessed all optical observation functions of general anorectal mirror; Among normal observation carries out or after; Can be through opening laser doppler processing host 4, OCT processing host 5 respectively or simultaneously; The laser doppler data acquisition module and the OCT data acquisition module that start on the telescopic head carry out laser doppler scanning and the observation of OCT tomoscan, and the telescopic head duration of work does not disturb the application of the common function of anorectal mirror.
More than the technical scheme that the embodiment of the invention provided has been carried out detailed introduction; Used concrete example among this paper the principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment only is applicable to the principle that helps to understand the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, the part that on the specific embodiment and range of application, all can change, in sum, this description should not be construed as limitation of the present invention.
Claims (8)
1. a laser doppler OCT enteroscope system comprises anorectal mirror and the cold light source main frame that is connected with this anorectal mirror and shooting main frame, it is characterized in that:
Said anorectal mirror is provided with laser doppler data acquisition module and OCT data acquisition module;
On said anorectal mirror, also be connected with Doppler's processing host that the data that said laser doppler data acquisition module is collected are carried out analyzing and processing;
On said anorectal mirror, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
2. laser doppler OCT enteroscope system according to claim 1 is characterized in that:
Said laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
3. laser doppler OCT enteroscope system according to claim 1 is characterized in that:
Said Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
4. according to each described laser doppler OCT enteroscope system of claim 1 to 3, it is characterized in that:
Said anorectal mirror comprises work end, cold light source joint, data connector, control module and instrument channel;
Said laser doppler data acquisition module and OCT data acquisition module are arranged on the anorectal mirror; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
5. laser doppler OCT enteroscope system according to claim 4 is characterized in that:
The diameter of said telescopic head is smaller or equal to 3 millimeters.
6. laser doppler OCT enteroscope system according to claim 4 is characterized in that:
On the first end of said work end, also being provided with optical fibers, optical lens and apparatus imports and exports.
7. laser doppler OCT enteroscope system according to claim 6 is characterized in that:
Said work end is processed by hard material, and the first end of this hard work end is blunt type;
The diameter of this hard work end is the 300-450 millimeter smaller or equal to 20 millimeters, length.
8. laser doppler OCT enteroscope system according to claim 6 is characterized in that:
It is the CCD optical lens of 1.5-3.0 millimeter that said optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100180698A CN102697471A (en) | 2012-01-18 | 2012-01-18 | Doppler laser optical coherence tomography (OCT) protoscope system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100180698A CN102697471A (en) | 2012-01-18 | 2012-01-18 | Doppler laser optical coherence tomography (OCT) protoscope system |
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| CN102697471A true CN102697471A (en) | 2012-10-03 |
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| CN2012100180698A Pending CN102697471A (en) | 2012-01-18 | 2012-01-18 | Doppler laser optical coherence tomography (OCT) protoscope system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109394161A (en) * | 2018-10-18 | 2019-03-01 | 朱奎阳 | A kind of laser doppler OCT enteroscope system |
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| CN2537345Y (en) * | 2002-02-05 | 2003-02-26 | 南开大学 | Double light beam laser Doppler blood flow instrument |
| US20070066871A1 (en) * | 2004-03-23 | 2007-03-22 | California Institute Of Technology Office Of Technology Transfer | Paired angled rotation scanning probes and methods of use |
| CN101686827A (en) * | 2007-01-19 | 2010-03-31 | 桑尼布鲁克健康科学中心 | Imaging probe with ultrasonic and optical imaging device of combination |
| CN102008285A (en) * | 2010-12-30 | 2011-04-13 | 广州宝胆医疗器械科技有限公司 | Integrative color Doppler ultrasound anorectal endoscope system |
| CN202426504U (en) * | 2012-01-18 | 2012-09-12 | 广州宝胆医疗器械科技有限公司 | Doppler laser OCT (optical coherence tomography) anorectal endoscope system |
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2012
- 2012-01-18 CN CN2012100180698A patent/CN102697471A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2537345Y (en) * | 2002-02-05 | 2003-02-26 | 南开大学 | Double light beam laser Doppler blood flow instrument |
| US20070066871A1 (en) * | 2004-03-23 | 2007-03-22 | California Institute Of Technology Office Of Technology Transfer | Paired angled rotation scanning probes and methods of use |
| CN101686827A (en) * | 2007-01-19 | 2010-03-31 | 桑尼布鲁克健康科学中心 | Imaging probe with ultrasonic and optical imaging device of combination |
| CN102008285A (en) * | 2010-12-30 | 2011-04-13 | 广州宝胆医疗器械科技有限公司 | Integrative color Doppler ultrasound anorectal endoscope system |
| CN202426504U (en) * | 2012-01-18 | 2012-09-12 | 广州宝胆医疗器械科技有限公司 | Doppler laser OCT (optical coherence tomography) anorectal endoscope system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109394161A (en) * | 2018-10-18 | 2019-03-01 | 朱奎阳 | A kind of laser doppler OCT enteroscope system |
| CN109394161B (en) * | 2018-10-18 | 2021-06-15 | 朱奎阳 | Doppler laser OCT anorectal endoscope system |
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Application publication date: 20121003 |