CN108309244A - A kind of novel pressure sensor skin capilary scanning means and system and working method - Google Patents
A kind of novel pressure sensor skin capilary scanning means and system and working method Download PDFInfo
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- CN108309244A CN108309244A CN201810149927.XA CN201810149927A CN108309244A CN 108309244 A CN108309244 A CN 108309244A CN 201810149927 A CN201810149927 A CN 201810149927A CN 108309244 A CN108309244 A CN 108309244A
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- 238000000034 method Methods 0.000 title claims description 18
- 239000000523 sample Substances 0.000 claims abstract description 61
- 230000005540 biological transmission Effects 0.000 claims abstract description 54
- 230000002500 effect on skin Effects 0.000 claims abstract description 12
- 210000004088 microvessel Anatomy 0.000 claims abstract description 12
- 241001269238 Data Species 0.000 claims description 13
- 238000012545 processing Methods 0.000 claims description 13
- 230000003287 optical effect Effects 0.000 claims description 12
- 238000003384 imaging method Methods 0.000 claims description 11
- 239000012528 membrane Substances 0.000 claims description 5
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 238000005259 measurement Methods 0.000 claims description 2
- 238000001228 spectrum Methods 0.000 claims description 2
- 238000012014 optical coherence tomography Methods 0.000 description 35
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000002583 angiography Methods 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 238000011835 investigation Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0064—Body surface scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
Abstract
A kind of novel pressure sensor skin capilary scanning means, including probing shell, handle, galvanometer holder, galvanometer, collimator, lens mount, lens, holder, light transmission piece；The light transmission piece lower surface is and diaphragm pressure sensor is arranged on skin contact surface.System with novel pressure sensor skin capilary scanning means, it includes novel pressure sensor skin capilary scanning means i.e. sample arm, reference arm, 10/90 coupler, circulator, SLD light sources, red-light source, spectrometer and computer.The present invention can directly measure pressure of the probe to skin surface using the diaphragm pressure sensor for being affixed on probe light transmission piece, and it is come out by Computer display, pressure is beyond certain zone of reasonableness, then computer can send out alert song, by adjusting pressure, it is ensured that reasonability and consistency of the OCT systems to Dermal microvessel scan depths.
Description
Technical field
The present invention relates to the fields OCT, especially a kind of novel pressure sensor skin capilary scanning means and system and work
Make method.
Background technology
Optical coherent chromatographic imaging（Optical Coherence Tomography, OCT）Technology is a kind of micron of fraction
The imaging technique of resolution scatters the amplitude and echo time delay of light by measurement, to obtain chromatography structure letter inside biological sample
Breath.OCT inhibits ambient noise using the weak coherence of broadband light, can get 1 ~ 2 quantity higher than traditional ultrasonic imaging
The resolution ratio of grade（μm grade）, and very high signal-to-noise ratio（More than 100dB）.OCT, as light source, will not be given using near infrared light
Human body brings harm.It, can also be to the effectively imaging of nontransparent tissue also, in addition to can be imaged to hyaline tissue.OCT ophthalmology,
The multiple fields application such as dept. of dermatology, intracardiac, enteron aisle, alimentary canal is also increasingly extensive.
Medically, the technology for based on tissue blood flow detection diagnose certain diseases also functions to the work of ever more important
With.Laser speckle blood current imaging technology, Doppler's OCT blood flow detections technology, the angiographic imaging based on OCT.Wherein newly go out
The existing Angiography based on OCT is novel vascular imaging technique.Laser speckle is imaged, and resolution ratio is relatively low, Zhi Nengguan
Examine bigger blood vessel.Doppler flow inaging detects, and is limited by the influence of detection angles, close to the detection angle of skin in probe
Its effect is excessively poor when vertical.Angiography based on OCT then has the advantages of high resolution, imaging is not influenced by angle.
But angiography needs probe to be affixed on skin surface in scanning process, in operation, if probe is to skin surface
Produced pressure is too small, and it will cause the shake increases between probe and skin surface；If probe produced by skin surface to pressing
Power is excessive, and it will cause the deformation of capilary under skin；And then collected vessel depth will be different strength difference,
Cause the inconsistency of diagnosis.So a kind of novel probe apparatus of urgent need can detect that probe is applied to the pressure of skin surface
Power.
A kind of novel pressure sensor skin capilary scanning means of present invention proposition and system, by probe and skin table
Diaphragm pressure sensor is installed in the light transmission piece of face contact, when pressure is more than certain zone of reasonableness（It is i.e. excessive or too small）Times
Alarm device can then sound, and pressure size of the probe to skin surface be adjusted manually, to reach the consistency and standard of OCT scan depth
True property.
Mentioned in patent document CN201310210400.0 a kind of skin area positioning device applied to blood sugar test,
Method and its system determine skin area to be measured using upper and lower plates windowed regions, to facilitate the detection of blood glucose.However it detected
Cheng Zhong then may result in system to pressure difference used in skin and change to the investigation depth of Dermal microvessel, and pressure
The deformation that conference causes capilary under skin is crossed, pressure is too small, and probe is easy to happen relative jitter with skin to be measured, to shadow
As picture quality.Woundless blood sugar acquisition, measuring device are mentioned in patent document CN203314969U, it being capable of automatic regulation of skin
The temperature of tested region, the scanning lens of the pressure being subject to and OCT measuring probes and skin tested region distance.However, should
Device can just adjust scanning lens and skin tested region distance after data acquisition, cause the operating time longer；The device
The cavity block vision used can not indicate light to position skin area to be measured by observation；The temperature control device that the device uses
The cost of probe has been significantly greatly increased with electricity driving displacement device；And the temperature control device that uses of the device and electricity driving displacement device are relatively
The big size for increasing probe.
Invention content
The purpose of the present invention is to provide a kind of novel pressure sensor skin capilary scanning means and system and work sides
Method, it can solve the deficiencies in the prior art, in OCT in the scanning process of Dermal microvessel, accurately showing OCT probe pair
The pressure of skin surface, when pressure is more than certain zone of reasonableness（It is i.e. excessive or too small）Times alarm device can then sound, manually
Probe is adjusted to the pressure of skin, ensure that OCT to the reasonability and consistency in skin scanning depth.
Technical scheme of the present invention：A kind of novel pressure sensor skin capilary scanning means, including probing shell,
Hand, galvanometer holder, galvanometer, collimator, lens mount, lens, holder, light transmission piece；The galvanometer holder is mounted in probing shell,
Galvanometer is mounted on galvanometer holder；The collimator is mounted on probing shell；The lens mount is mounted on probing shell, thoroughly
Mirror is mounted on lens mount；Holder is arranged in the side of the mounted lens of the probing shell, and light transmission piece, light path warp are installed on holder
Cross lens and light transmission piece；The handle is connect with probing shell；It is characterized in that the light transmission piece lower surface i.e. and skin contact
Diaphragm pressure sensor is set on face.
The light transmission piece lower surface is in lens focus position, diaphragm pressure sensor be in optical scanning less than, do not influence
The position of the transmission of light path.
The diaphragm pressure sensor is the circular membrane of a diameter of 8 ± 1mm, and thickness is 0.2~0.3mm.
The light transmission piece is the thin rounded flakes of a diameter of 4~5cm, and thickness is 1 ± 0.1mm.
A kind of system with novel pressure sensor skin capilary scanning means, it is characterised in that it includes novel pressure
Sensor skin capilary scanning means, that is, sample arm, reference arm, 10/90 coupler, circulator, SLD light sources, red-light source, light
Spectrometer and computer；SLD light sources send out ultra-wideband light and pass through circulator and 10/90 coupler, and 10% light enters reference arm,
90% light enters sample arm；The light returned from sample arm and reference arm interferes in coupler, by circulator by spectrum
Instrument acquisition conversion, then be transferred in computer and carry out processing imaging；The diaphragm pressure sensor of the sample arm is affixed on sample arm
Light transmission piece after be connected to computer, scanning Computer shows probe that diaphragm pressure sensor measures to skin surface
Pressure.
The working method of the novel pressure sensor skin capilary scanning means, includes the following steps：
Step（1）, the skin site of feux rouges determination scanning：Skin area to be measured is selected, handle is held, will indicate light perpendicular alignmnet
Skin site to be measured；
Step（2）, light transmission piece is affixed on skin site to be measured：After indicating optical registration region to be measured, light transmission piece is slowly affixed on and is waited for
Survey skin；Hand-held handle, slight mobile probe make instruction optical scanning region be completely superposed with skin area to be measured；
Step（3）：Computer reads probe to skin pressure numerical value：After light transmission piece is affixed on skin position to be measured, pop one's head in skin
Surface applies certain pressure, while skin applies same pressure in light transmission piece surface, and the diaphragm pressure for being affixed on light transmission piece surface passes
Sensor reads pressure value under the premise of not influencing optic path by computer, and then display is normal in the reasonable scope for pressure,
Computer can send out prompt if pressure is excessive or too small；
Step（4）, by numerical value adjustment probe to skin pressing dynamics：During scan skin capilary, pass through number pressure
Value manually adjusts probe to the pressure of skin surface, makes pressure in the reasonable scope.
The working method of the system with novel pressure sensor skin capilary scanning means, includes the following steps：
Step（1）, scanning collection capilary image：The light that the light returned from sample arm is returned with reference arm occurs in coupler
Interference, by circulator by spectrometer collection, then is transferred in computer；Computer is for the analyzing processing three-dimensional OCT image；
When being scanned using sample arm, the scanning area of OCT within the scope of light transmission piece, and diaphragm pressure sensor be affixed on light transmission piece compared with
For edge optical scanning less than place, do not influence the transmission and scanning of light path；OCT three-dimensional datas will be transmitted to computer and analyze
Processing；
Step（2）, acquisition information is extracted, handled and is imaged：It is micro- that area skin to be measured is extracted from OCT three-dimensional datas
The OCT three-dimensional datas of blood vessel are further processed OCT three-dimensional datas using image processing techniques.
The superiority of the present invention：1, during scan skin capilary, the then micro- blood of skin excessive to skin pressure of popping one's head in
Pipe can deform upon；Pressure is too small, then probe and skin surface are easy to happen shake, it is difficult to ensure reasonable in scan depths
Property, and pressure size is different in scanning process, then the vessel depth measured can be varied from, it is difficult to ensure one in scan depths
Cause property.The present invention can directly measure pressure of the probe to skin surface using the diaphragm pressure sensor for being affixed on probe light transmission piece
Power, and being come out by Computer display, for pressure beyond certain zone of reasonableness, then computer can send out alert song, pass through adjusting
Pressure, it is ensured that reasonability and consistency of the OCT systems to Dermal microvessel scan depths.2, the present invention is made by increasing light transmission piece
Scanning lens and skin tested region distance are fixed, keep scanning more quick；Present invention is mainly applied to detect skin blood capillary
Pipe, at normal temperatures, temperature change influences it less, so being not necessarily to temperature control device；Present invention probe is hand-held, and operation is more
It is convenient.
Description of the drawings
Fig. 1 is a kind of novel pressure sensor skin capilary scanning means figure involved by the present invention；
Fig. 2 is a kind of novel pressure sensor skin capilary scanning system figure involved by the present invention；
Fig. 3 is that OCT systems extract flow chart to Dermal microvessel.
Specific implementation mode
Embodiment：To solve in previous OCT systems detect Dermal microvessel, then skin excessive to skin pressure of popping one's head in
Capilary can deform upon, and pressure is too small, then probe and skin surface are easy to happen shake, and pressure size is not in scanning process
Together, then the vessel depth measured can be varied from, it is difficult to ensure the problems such as consistency in scan depths, present embodiment provides
A kind of novel pressure sensor skin capilary scanning means and system, with reference to specific embodiment, to being applied to novel pressure
Dermal microvessel extraction flow chart is specifically described in power sensor skin capilary scanning means figure, system diagram and system.
Such as Fig. 1, present embodiment provides a kind of novel pressure sensor skin capilary scanning means, it includes probing shell
110, handle 111, galvanometer holder 112, galvanometer 113, collimator 114, lens mount 115, lens 116, holder 117, light transmission piece
118, diaphragm pressure sensor 119.The galvanometer holder 112 is mounted in probing shell 110, and galvanometer 113 is mounted on galvanometer branch
On frame 112；The collimator 114 is mounted on probing shell 110；The lens mount 115 is mounted on probing shell 110, thoroughly
Mirror 116 is mounted on lens mount 115；Holder 117, holder 117 is arranged in the side of the mounted lens 116 of the probing shell 110
Upper installation light transmission piece 118, light path pass through lens 116 and light transmission piece 118；The handle 111 is connect with probing shell 110；Light transmission
Piece 118 is fixed on screw on holder 117；Diaphragm pressure sensor 119 is with double faced adhesive tape in light transmission piece lower surface（That is, with
Skin surface contact surface）.When light transmission piece 118 is affixed on skin surface, skin surface generates pressure to diaphragm pressure sensor 119
Power can then measure pressure of the probe to skin surface to be measured；And diaphragm pressure sensor 119 is affixed on the scanning of light transmission piece light path not
The place arrived, does not influence optic path.
The diaphragm pressure sensor is the circular membrane of a diameter of 8mm, thickness 0.2mm.
The light transmission piece is the thin rounded flakes of a diameter of 4cm, thickness 1mm.
Such as Fig. 2, present embodiment provides a kind of novel pressure sensor skin capilary scanning system, it includes sample arm
120（That is, novel pressure sensor skin capilary scanning means）, reference arm 130, spectrometer 140,10/90 coupling/150, annular
Device 160, red-light source 170, SLD light sources 180 and computer 190.Wherein, reference arm 130 includes collimator 131, lens 132
With plane mirror 133；Spectrometer 140 includes collimator 141, lens 142, grating 143, lens 144 and CCD camera 145.It is thin
Membrane pressure sensor is directly connected in computer.SLD light sources 180 send out ultra-wideband light and pass through circulator 160 and 10/90 coupling
Clutch 150,10% light enter reference arm 130, and 90% light enters sample arm 120；It is returned from sample arm 120 and reference arm 130
Light interfered in coupler 150, acquired and convert by spectrometer 140 by circulator 160, then be transferred to computer 190
In carry out processing imaging；Diaphragm pressure sensor 119 is directly connected in computer 190.When skin surface passes diaphragm pressure
When sensor 119 generates pressure, computer can show the numerical value of pressure, and when numerical value is more than certain zone of reasonableness, then computer is sent out
Go out alarm song.Probe is adjusted manually to skin surface pressure, it is ensured that the consistency in OCT scan depth and reasonability.
In the following, we combine above-mentioned novel pressure sensor skin capilary scanning means and system to OCT systems to skin
Capilary extraction flow is described.
Flow is extracted to Dermal microvessel as shown in figure 3, present embodiments provide for OCT systems, is included the following steps：
S100, feux rouges determine the skin site of scanning.Skin area to be measured is selected, handle 111 is held, will indicate light perpendicular alignmnet
With skin site to be measured.
S200, light transmission piece is affixed on skin site to be measured.After indicating optical registration region to be measured, light transmission piece 118 is slowly pasted
In skin to be measured.Hand-held handle 111, slight mobile probe make instruction optical scanning region be completely superposed with skin area to be measured.This
Sample can be such that the relative jitter between sample arm 120 and skin region to be measured reduces, and improve the stability in detection process.
S300, computer read probe to skin pressure numerical value.After light transmission piece 118 is affixed on skin position to be measured, probe pair
Skin surface applies certain pressure, while skin applies same pressure in 118 surface of light transmission piece, is affixed on 118 surface of light transmission piece
Diaphragm pressure sensor 119 can read pressure value under the premise of not influencing optic path by computer 190.Pressure is one
Determine then to show that normally computer can sound the alarm if pressure is excessive or too small in zone of reasonableness.
S400, it is popped one's head in skin pressing dynamics by numerical value adjustment.During scan skin capilary, pop one's head in skin
Pressure is excessive, and Dermal microvessel can deform upon；Pressure is too small, then probe and skin surface are easy to happen shake, it is difficult to ensure
Reasonability in scan depths.And pressure size is different in scanning process, then the vessel depth measured can be varied from, it is difficult to really
Protect the consistency in scan depths.During the test, pressure of the probe to skin surface is manually adjusted by pressure value,
Make pressure in the reasonable scope, it is ensured that OCT is to the reasonability and consistency in Dermal microvessel scan depths.
S500, scanning collection capilary image.Referring to FIG. 2, in the present embodiment, additionally providing novel pressure sensing
Dermal microvessel scanning system.The light that the light returned from sample arm 120 is returned with reference arm 130 occurs dry in coupler 150
It relates to, is acquired by spectrometer 140 by circulator 160, then be transferred in computer 190.Computer 190 for analyzing processing this three
Tie up OCT image.When being scanned using sample arm 120, need the scanning area for ensureing OCT within the scope of light transmission piece 118, and thin
Membrane pressure sensor 119 be affixed on light transmission piece more edge optical scanning less than place, do not influence the transmission and scanning of light path.These
OCT three-dimensional datas will be transmitted to computer 190 and carry out analyzing processing.
S600, acquisition information is extracted, handled and is imaged.Since the OCT three-dimensional datas of step S500 had both included waiting for
The OCT three-dimensional datas for surveying area skin capilary, further include the three-dimensional data of skin surface, it would therefore be desirable to from OCT tri-
The OCT three-dimensional datas of area skin capilary to be measured are extracted in dimension data.In addition, the OCT-A three-dimensional datas of step S500 are only
It is the data that initial acquisition arrives, we have carried out further processing using image processing techniques to it.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (7)
1. a kind of novel pressure sensor skin capilary scanning means, including probing shell, handle, galvanometer holder, galvanometer, collimation
Device, lens mount, lens, holder, light transmission piece；The galvanometer holder is mounted in probing shell, and galvanometer is mounted on galvanometer holder；
The collimator is mounted on probing shell；The lens mount is mounted on probing shell, and lens are mounted on lens mount；It is described
Holder is arranged in the side of the mounted lens of probing shell, and light transmission piece is installed on holder, and light path passes through lens and light transmission piece；Described
Hand is connect with probing shell；It is characterized in that the light transmission piece lower surface is sensed with setting diaphragm pressure on skin contact surface
Device.
2. a kind of novel pressure sensor skin capilary scanning means according to claim 1, it is characterised in that the light transmission
Piece lower surface is in lens focus position, diaphragm pressure sensor be in optical scanning less than, do not influence light path transmission position.
3. a kind of novel pressure sensor skin capilary scanning means according to claim 1, it is characterised in that the film
Pressure sensor is the circular membrane of a diameter of 8 ± 1mm, and thickness is 0.2~0.3mm.
4. a kind of novel pressure sensor skin capilary scanning means according to claim 1, it is characterised in that the light transmission
Piece is the thin rounded flakes of a diameter of 4~5cm, and thickness is 1 ± 0.1mm.
5. a kind of system with novel pressure sensor skin capilary scanning means, it is characterised in that it includes that novel pressure passes
Feel Dermal microvessel scanning means, that is, sample arm, reference arm, 10/90 coupler, circulator, SLD light sources, red-light source, spectrum
Instrument and computer；SLD light sources send out ultra-wideband light and pass through circulator and 10/90 coupler, and 10% light enters reference arm, and 90%
Light enter sample arm；The light returned from sample arm and reference arm interferes in coupler, by circulator by spectrometer
Acquisition conversion, then be transferred in computer and carry out processing imaging；The diaphragm pressure sensor of the sample arm is affixed on sample arm
Computer is connected to after light transmission piece, scanning Computer shows pressure of the probe to skin surface of diaphragm pressure sensor measurement
Power.
6. the working method of novel pressure sensor skin capilary scanning means described in a kind of claim 1, it is characterised in that packet
Include following steps：
Step（1）, the skin site of feux rouges determination scanning：Skin area to be measured is selected, handle is held, will indicate light perpendicular alignmnet
Skin site to be measured；
Step（2）, light transmission piece is affixed on skin site to be measured：After indicating optical registration region to be measured, light transmission piece is slowly affixed on and is waited for
Survey skin；Hand-held handle, slight mobile probe make instruction optical scanning region be completely superposed with skin area to be measured；
Step（3）：Computer reads probe to skin pressure numerical value：After light transmission piece is affixed on skin position to be measured, pop one's head in skin
Surface applies certain pressure, while skin applies same pressure in light transmission piece surface, and the diaphragm pressure for being affixed on light transmission piece surface passes
Sensor reads pressure value under the premise of not influencing optic path by computer, and then display is normal in the reasonable scope for pressure,
Computer can send out prompt if pressure is excessive or too small；
Step（4）, by numerical value adjustment probe to skin pressing dynamics：During scan skin capilary, pass through number pressure
Value manually adjusts probe to the pressure of skin surface, makes pressure in the reasonable scope.
7. the working method of the system with novel pressure sensor skin capilary scanning means described in a kind of claim 5,
It is characterized in that including the following steps：
Step（1）, scanning collection capilary image：The light that the light returned from sample arm is returned with reference arm occurs in coupler
Interference, by circulator by spectrometer collection, then is transferred in computer；Computer is for the analyzing processing three-dimensional OCT image；
When being scanned using sample arm, the scanning area of OCT within the scope of light transmission piece, and diaphragm pressure sensor be affixed on light transmission piece compared with
For edge optical scanning less than place, do not influence the transmission and scanning of light path；OCT three-dimensional datas will be transmitted to computer and analyze
Processing；
Step（2）, acquisition information is extracted, handled and is imaged：It is micro- that area skin to be measured is extracted from OCT three-dimensional datas
The OCT three-dimensional datas of blood vessel are further processed OCT three-dimensional datas using image processing techniques.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222897A (en) * | 2018-08-01 | 2019-01-18 | 中日友好医院 | Skin Laser Scanning Confocal Microscope probe pressure measuring unit |
| CN111000532A (en) * | 2019-07-16 | 2020-04-14 | 南昌航空大学 | Oral cavity soft tissue detection device and method based on optical Doppler imaging |
| CN111248863A (en) * | 2020-01-19 | 2020-06-09 | 国家康复辅具研究中心 | Pressurizing device for inducing human skin hyperemia response |
| CN111493930A (en) * | 2020-04-24 | 2020-08-07 | 天津恒宇医疗科技有限公司 | Novel endoscopic blood flow imaging and blood flow parameter quantification method and system |
| CN111493853A (en) * | 2020-04-24 | 2020-08-07 | 天津恒宇医疗科技有限公司 | Blood vessel parameter evaluation method and system for angiodermic diseases |
| CN112773335A (en) * | 2021-02-07 | 2021-05-11 | 苏州大学 | Sensor, imaging system and imaging method applied to optical coherent elastography |
| CN114468991A (en) * | 2021-02-11 | 2022-05-13 | 先阳科技有限公司 | Method and device for inhibiting jitter influence and wearable equipment |
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