CN102696034B - 基于基因拷贝数改变的模式的非小细胞肺癌的基因组分类 - Google Patents

基于基因拷贝数改变的模式的非小细胞肺癌的基因组分类 Download PDF

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CN102696034B
CN102696034B CN200980143555.9A CN200980143555A CN102696034B CN 102696034 B CN102696034 B CN 102696034B CN 200980143555 A CN200980143555 A CN 200980143555A CN 102696034 B CN102696034 B CN 102696034B
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nci
sample
subgroup
clone
algorithm
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CN102696034A (zh
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D·塞米扎洛夫
卢欣
K·张
R·R·列斯尼夫斯基
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AbbVie Inc
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/60—ICT specially adapted for the handling or processing of medical references relating to pathologies
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
CN200980143555.9A 2008-10-31 2009-10-28 基于基因拷贝数改变的模式的非小细胞肺癌的基因组分类 Expired - Fee Related CN102696034B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11031708P 2008-10-31 2008-10-31
US11028108P 2008-10-31 2008-10-31
US61/110,281 2008-10-31
US61/110281 2008-10-31
US61/110317 2008-10-31
US61/110,317 2008-10-31
PCT/US2009/062388 WO2010051314A2 (en) 2008-10-31 2009-10-28 Genomic classification of non-small cell lung carcinoma based on patterns of gene copy number alterations

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CN102696034A CN102696034A (zh) 2012-09-26
CN102696034B true CN102696034B (zh) 2016-01-20

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US (1) US8498820B2 (ja)
EP (1) EP2362958A2 (ja)
JP (1) JP5632382B2 (ja)
CN (1) CN102696034B (ja)
CA (1) CA2739457A1 (ja)
MX (1) MX2011004588A (ja)
WO (1) WO2010051314A2 (ja)

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EP2870479A1 (en) * 2012-07-05 2015-05-13 Biodesix, Inc. Method for predicting whether a cancer patient will not benefit from platinum-based chemotherapy agents
US9449143B2 (en) 2012-08-28 2016-09-20 Inova Health System Ancestral-specific reference genomes and uses thereof
JP6469033B2 (ja) * 2016-02-18 2019-02-13 日本電信電話株式会社 分布推定装置、分布推定方法、及び分布推定プログラム
CN106055923A (zh) * 2016-05-13 2016-10-26 万康源(天津)基因科技有限公司 一种基因拷贝数变异分析方法
WO2017205691A1 (en) 2016-05-26 2017-11-30 Cellular Research, Inc. Molecular label counting adjustment methods
CN109952612B (zh) * 2016-11-08 2023-12-01 贝克顿迪金森公司 用于表达谱分类的方法
JP7228510B2 (ja) 2016-11-08 2023-02-24 ベクトン・ディキンソン・アンド・カンパニー 細胞標識分類の方法
US20200224277A1 (en) * 2017-07-17 2020-07-16 Mao Ying Genetech Inc. Cell type identification method and system thereof
ES2711163B2 (es) * 2017-10-23 2021-04-14 Health In Code S L Sistema y método de detección de variantes genéticas estructurales.
CN109192246B (zh) * 2018-06-22 2020-10-16 深圳市达仁基因科技有限公司 检测染色体拷贝数异常的方法、装置和存储介质
CN109887544B (zh) * 2019-01-22 2022-07-05 广西大学 基于非负矩阵分解的rna序列并行分类方法
US20220341939A1 (en) * 2019-02-15 2022-10-27 Biodesix, Inc. Predictive test for identification of early stage nsclc stage patients at high risk of recurrence after surgery
CN111863159B (zh) * 2020-06-01 2022-02-25 中山大学孙逸仙纪念医院 一种肿瘤免疫治疗疗效预测的列线图模型的建立方法

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JP5632382B2 (ja) 2014-11-26
US20100145893A1 (en) 2010-06-10
JP2012513048A (ja) 2012-06-07
WO2010051314A3 (en) 2012-04-05
CA2739457A1 (en) 2010-05-06
CN102696034A (zh) 2012-09-26
WO2010051314A2 (en) 2010-05-06
MX2011004588A (es) 2011-08-03
EP2362958A2 (en) 2011-09-07
US8498820B2 (en) 2013-07-30

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