CN102695532B - 用于药物传输装置的驱动组件和药物传输装置 - Google Patents

用于药物传输装置的驱动组件和药物传输装置 Download PDF

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Publication number
CN102695532B
CN102695532B CN201080060957.5A CN201080060957A CN102695532B CN 102695532 B CN102695532 B CN 102695532B CN 201080060957 A CN201080060957 A CN 201080060957A CN 102695532 B CN102695532 B CN 102695532B
Authority
CN
China
Prior art keywords
drive element
housing
piston rod
guide
relative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080060957.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN102695532A (zh
Inventor
U.达斯巴赫
S.拉布
M.罗特勒夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CN102695532A publication Critical patent/CN102695532A/zh
Application granted granted Critical
Publication of CN102695532B publication Critical patent/CN102695532B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/482—Varying injection pressure, e.g. by varying speed of injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201080060957.5A 2009-12-07 2010-12-06 用于药物传输装置的驱动组件和药物传输装置 Expired - Fee Related CN102695532B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09178215 2009-12-07
EP09178215.1 2009-12-07
PCT/EP2010/068916 WO2011069936A1 (en) 2009-12-07 2010-12-06 Drive assembly for a drug delivery device and drug delivery device

Publications (2)

Publication Number Publication Date
CN102695532A CN102695532A (zh) 2012-09-26
CN102695532B true CN102695532B (zh) 2015-02-18

Family

ID=42455318

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080060957.5A Expired - Fee Related CN102695532B (zh) 2009-12-07 2010-12-06 用于药物传输装置的驱动组件和药物传输装置

Country Status (10)

Country Link
US (1) US9022993B2 (https=)
EP (1) EP2509663B1 (https=)
JP (1) JP5816191B2 (https=)
CN (1) CN102695532B (https=)
AU (1) AU2010330033B2 (https=)
BR (1) BR112012013767A2 (https=)
CA (1) CA2779389A1 (https=)
DK (1) DK2509663T3 (https=)
IL (1) IL220169A (https=)
WO (1) WO2011069936A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
CN102612381B (zh) 2009-03-20 2015-09-09 安塔瑞斯制药公司 危险试剂注入系统
US20120283652A1 (en) * 2009-09-30 2012-11-08 Sanofi-Aventis Deutschland Gmbh Assembly and Piston Rod for a Drug Delivery Device
EP2399635A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
WO2012050511A1 (en) * 2010-10-11 2012-04-19 Shl Group Ab Medicament delivery device
USRE48593E1 (en) 2010-12-21 2021-06-15 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2468333A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
JP6057991B2 (ja) * 2011-06-17 2017-01-11 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物送達デバイス用カートリッジ・ホルダ・アセンブリ
EP2606924A1 (en) 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector having a retracting syringe carrier
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
ES2969984T3 (es) 2013-02-11 2024-05-23 Antares Pharma Inc Dispositivo de inyección por chorro asistido por aguja que tiene fuerza de disparo reducida
JP6030803B2 (ja) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド ピニオンシステムを有する用量注射器
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
EP2823841A1 (en) 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
EP2923714A1 (en) 2014-03-28 2015-09-30 Sanofi-Aventis Deutschland GmbH Autoinjector triggered by skin contact
CN110913926B (zh) * 2017-06-08 2022-07-15 诺瓦提斯公司 注射装置及注射液输送系统
US20220168510A1 (en) * 2019-04-09 2022-06-02 Congruence Medical Solutions, Llc Injection Device
US11577028B2 (en) * 2021-01-20 2023-02-14 Becton, Dickinson And Company Syringe with a bidirectional plunger advancing mechanism for a micro-dosing syringe pump

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4475905A (en) * 1982-09-30 1984-10-09 Himmelstrup Anders B Injection device
WO2000062847A1 (en) * 1999-04-16 2000-10-26 Pharmacia Ab Injector device and method for its operation
US20060229570A1 (en) * 2002-09-11 2006-10-12 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
WO2009136209A1 (en) * 2008-05-09 2009-11-12 Owen Mumford Limited Electrically actuated injector

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256152A (en) * 1991-10-29 1993-10-26 Marks Lloyd A Safety needle and method of using same
GB9300567D0 (en) * 1993-01-12 1993-03-03 Owen Mumford Ltd Improvements relating to devices for generating intermittent motion
DE19822031C2 (de) 1998-05-15 2000-03-23 Disetronic Licensing Ag Autoinjektionsgerät
US8771237B2 (en) * 2007-12-20 2014-07-08 Novo Nordisk A/S Injection device for delivering a fixed dose of liquid drug

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4475905A (en) * 1982-09-30 1984-10-09 Himmelstrup Anders B Injection device
WO2000062847A1 (en) * 1999-04-16 2000-10-26 Pharmacia Ab Injector device and method for its operation
US20060229570A1 (en) * 2002-09-11 2006-10-12 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
WO2009136209A1 (en) * 2008-05-09 2009-11-12 Owen Mumford Limited Electrically actuated injector

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly

Also Published As

Publication number Publication date
IL220169A (en) 2014-06-30
US9022993B2 (en) 2015-05-05
DK2509663T3 (en) 2015-04-27
EP2509663B1 (en) 2015-01-21
CA2779389A1 (en) 2011-06-16
US20130018327A1 (en) 2013-01-17
HK1176898A1 (en) 2013-08-09
AU2010330033A1 (en) 2012-06-21
JP5816191B2 (ja) 2015-11-18
AU2010330033B2 (en) 2014-10-23
IL220169A0 (en) 2012-07-31
JP2013512744A (ja) 2013-04-18
CN102695532A (zh) 2012-09-26
WO2011069936A1 (en) 2011-06-16
EP2509663A1 (en) 2012-10-17
BR112012013767A2 (pt) 2016-04-26

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150218

Termination date: 20161206